The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform
Iis P Tussyadiah - One of the best experts on this subject based on the ideXlab platform.
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a review of research into automation in tourism launching the annals of tourism research curated collection on artificial intelligence and robotics in tourism
Annals of Tourism Research, 2020Co-Authors: Iis P TussyadiahAbstract:Driven by the advancements in artificial intelligence (AI) and its related technologies, the application of intelligent automation in travel and tourism is expected to increase in the future. This paper unpacks the need to shape an automated future of tourism as a social phenomenon and an economic activity, hence contributes to theory and practice by providing directions for future research in this area. Four research priorities are suggested: designing beneficial AI, facilitating adoption, assessing the impacts of intelligent automation, and creating a sustainable future with artificial intelligence. Research in these areas will allow for a Systematic Knowledge production that reflects a concerted effort from the scientific community to ensuring the beneficial applications of intelligent automation in tourism.
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a review of research into automation in tourism launching the annals of tourism research curated collection on artificial intelligence and robotics in tourism
Annals of Tourism Research, 2020Co-Authors: Iis P TussyadiahAbstract:Abstract Driven by the advancements in artificial intelligence (AI) and its related technologies, the application of intelligent automation in travel and tourism is expected to increase in the future. This paper unpacks the need to shape an automated future of tourism as a social phenomenon and an economic activity, hence contributes to theory and practice by providing directions for future research in this area. Four research priorities are suggested: designing beneficial AI, facilitating adoption, assessing the impacts of intelligent automation, and creating a sustainable future with artificial intelligence. Research in these areas will allow for a Systematic Knowledge production that reflects a concerted effort from the scientific community to ensuring the beneficial applications of intelligent automation in tourism. The article also launches the Annals of Tourism Research Curated Collection on Artificial Intelligence and Robotics. The Collection contains all past articles published in Annals of Tourism Research on the topic, and continues to grow as new articles are added.
Dimitris Kardassis - One of the best experts on this subject based on the ideXlab platform.
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regulatory gene mutations affecting apolipoprotein gene expression functions and regulatory behavior of known genes may guide future pharmacogenomic approaches to therapy
Clinical Chemistry and Laboratory Medicine, 2003Co-Authors: Vassilis I Zannis, Tong Liu, Markella V Zanni, Horngyuan Kan, Dimitris KardassisAbstract:A pharmacogenomic approach to therapy requires Systematic Knowledge of the regulatory regions of the genes, as well as basic understanding of transcriptional regulatory mechanisms of genes. Using the apolipoprotein (apo) A-I/CIII gene cluster as a model system, we have identified by in vitro and in vivo studies the regulatory elements and the factors which control its transcription. Studies in transgenic mice established that the hepatocyte nuclear factor (HNF-4) binding site of the apoCIII enhancer, which controls transcription of both genes, is required for the intestinal expression of apoA-I and apoCIII genes, and enhances synergistically their hepatic transcription in vivo. The three Sp1 sites of the enhancer are also required for the intestinal expression of apoA-land apoC-III genes in vivo, and for the enhancement of the hepatic transcription. The regulation of the apoE/apoCl/ apoCIV/apoCII cluster is also cited. It is expected that identification of the regulatory regions of genes will be soon accelerated by the sequencing of several mammalian genomes. The functional analyses of the regulatory domains of genes involved in lipid homeostasis, combined with cross-species sequence comparisons in the near future, may identify natural regulatory gene polymorphisms in the general population that will permit rational pharmacogenomic approaches for treatment of dyslipidemias.
James Wyckoff - One of the best experts on this subject based on the ideXlab platform.
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measure for measure the relationship between measures of instructional practice in middle school english language arts and teachers value added scores
American Journal of Education, 2013Co-Authors: Pam Grossman, Susanna Loeb, Julia Cohen, James WyckoffAbstract:Over the past 2 years, educational policy makers have focused much of their attention on issues related to teacher effectiveness. The Obama administration has made teacher evaluation and teacher quality a central feature of many of its educational policies, including Race to the Top (RTTT), Investing in Innovation (i3), and the Teacher Incentive Fund (TIF) grants. In response, many states and school districts are developing measures of teacher effectiveness to reward, tenure, support, and fire teachers. In response to these policies, many observers are raising questions and concerns about the measures of teacher effectiveness that inform high-stakes personnel decisions. Unfortunately, we have little Systematic Knowledge regarding the properties of most of these measures. This article has two goals: to explore elements of instruction that may be associated with improved student achievement and to examine the domains of teaching skills that are identified in the literature as important to high-quality teach...
Kuohung Tseng - One of the best experts on this subject based on the ideXlab platform.
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the impact of problem based learning strategies on stem Knowledge integration and attitudes an exploratory study among female taiwanese senior high school students
International Journal of Technology and Design Education, 2011Co-Authors: Shijer Lou, Ruchu Shih, Ray C Diez, Kuohung TsengAbstract:This study was designed to explore the effects of problem-based learning (PBL) strategies on the attitudes of female senior high school students toward integrated Knowledge learning in science, technology, engineering, and mathematics (STEM). Content analysis and focus group methods were adopted as the research processes. Data and information about the STEM internet platform, an attitude scale and the contents of interviews were also collected for analysis. The subjects were 10th grade students at a girls’ senior high school who volunteered to organize teams for a Solar Electric Trolley Contest. A total of 40 students were grouped into 18 teams. The results of the study indicate: (1) that PBL strategies can be helpful in enhancing students’ attitudes toward STEM learning and the exploration of future career choices; (2) that the PBL teaching strategy helped to lead students step by step toward completing the contest’s mission and to experience the meaning of integrated STEM Knowledge; (3) that not only that students can actively apply engineering and science Knowledge, but also that students tend to gain more solid science and mathematics Knowledge through STEM learning in PBL; and (4) that PBL can enhance students’ abilities and provide them experiences related to Knowledge integration and application. Therefore, it is recommended that the curriculum at the girls’ senior high school include more content related to specialty subjects to enhance their technological capabilities. In addition, a learning mechanism should be offered to aid advisers or teachers in strengthening students’ integrated and Systematic Knowledge about STEM.
Sergey V. Popov - One of the best experts on this subject based on the ideXlab platform.
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Interdisciplinary approach to compensation of hypoglycemia in diabetic patients with chronic heart failure
Heart Failure Reviews, 2017Co-Authors: Yana Anfinogenova, Elena V. Grakova, Maria Shvedova, Kristina V. Kopieva, Alexander T. Teplyakov, Sergey V. PopovAbstract:Diabetes mellitus is a chronic disease requiring lifelong control with hypoglycemic agents that must demonstrate excellent efficacy and safety profiles. In patients taking glucose-lowering drugs, hypoglycemia is a common cause of death associated with arrhythmias, increased thrombus formation, and specific effects of catecholamines due to sympathoadrenal activation. Focus is now shifting from merely glycemic control to multifactorial approach. In the context of individual drugs and classes, this article reviews interdisciplinary strategies evaluating metabolic effects of drugs for treatment of chronic heart failure (CHF) which can mask characteristic hypoglycemia symptoms. Hypoglycemia unawareness and cardiac autonomic neuropathy are discussed. Data suggesting that hypoglycemia modulates immune response are reviewed. The potential role of gut microbiota in improving health of patients with diabetes and CHF is emphasized. Reports stating that nondiabetic CHF patients can have life-threatening hypoglycemia associated with imbalance of thyroid hormones are discussed. Regular glycemic control based on HbA1c measurements and adequate pharmacotherapy remain the priorities in diabetes management. New antihyperglycemic drugs with safer profiles should be preferred in vulnerable CHF patients. Multidrug interactions must be considered. Emerging therapies with reduced hypoglycemia risk, telemedicine, sensor technologies, and genetic testing predicting hypoglycemia risk may help solving the challenges of hypoglycemia in CHF patients with diabetes. Interdisciplinary work may involve cardiologists, diabetologists/endocrinologists, immunologists, gastroenterologists, microbiologists, nutritionists, imaging specialists, geneticists, telemedicine experts, and other relevant specialists. This review emphasizes that Systematic Knowledge on pathophysiology of hypoglycemia in diabetic patients with CHF is largely lacking and the gaps in our understanding require further discoveries.
