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Jari A Laukkanen - One of the best experts on this subject based on the ideXlab platform.
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T Wave Inversion and morTaliTy risk
Annals of Medicine, 2015Co-Authors: Sudhir Kurl, Timo H Makikallio, Jari A LaukkanenAbstract:AbsTracTObjecTive. To invesTigaTe The predicTive value of T-Wave Inversion (TWI) on rouTine elecTrocardiogram (ECG) for morTaliTy in The general populaTion wiTh various risk groups in a prospecTive populaTion-based follow-up sTudy.SubjecTs. ECGs of a random populaTion-based sample of 1814 men aged 42–60 years wiThouT coronary hearT disease (CHD) aT baseline.ResulTs. During an average follow-up of 21 years, 685 deaThs occurred. Of These deaThs 174 were due To CHD and 278 To cardiovascular disease (CVD). There were 57 subjecTs wiTh TWI. AfTer adjusTing for age, TWI was associaTed wiTh an increased CHD morTaliTy (relaTive risk (RR) 4.10, 95% CI 2.26–7.41), CVD morTaliTy (RR 3.47, 95% CI 2.09–5.78), and all-cause morTaliTy (RR 2.07, 95% CI 1.37–3.12). AfTer furTher adjusTmenT for convenTional risk facTors, TWI remained sTaTisTically significanT, predicTing CHD morTaliTy (RR 2.62, 95% CI 1.57–4.36), CVD morTaliTy (RR 2.18, 95% CI 1.40–3.38), and all-cause morTaliTy (RR 1.41, 95% CI 1.00–2.01), respecTively.Con...
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T Wave Inversion qrs duraTion and qrs T angle as elecTrocardiographic predicTors of The risk for sudden cardiac deaTh
American Journal of Cardiology, 2014Co-Authors: Jari A Laukkanen, Sudhir Kurl, Hassan Khan, Emanuele Di Angelantonio, Kimmo Ronkainen, Pentti M RautaharjuAbstract:The aim of This sTudy was To invesTigaTe The prognosTic uTiliTy of isolaTed T-Wave Inversion (TWI), QRS duraTion, and QRS/T angle on elecTrocardiogram aT resT as predicTors for sudden cardiac deaTh (SCD) and deaTh from all causes. The assessmenT of elecTrocardiographic findings was based on a populaTion-based cohorT of 1,951 men (age 42 To 61 years) wiTh a follow-up period of 20 years. IsolaTed TWI in The absence of ST depression, bundle branch block or major arrhyThmias, prolonged QRS duraTion from 110 To 119 ms, and a wide QRS/T angle of >67° were idenTified from The 12-lead elecTrocardiograms. SCD was observed in 171 men (8.3%) during The follow-up. As a single elecTrocardiographic parameTer, TWI (prevalence 2.4%) was associaTed wiTh an increased risk of SCD (hazard raTio [HR] 3.30, 95% confidence inTerval [CI] 1.91 To 5.71, p
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T Wave Inversion on elecTrocardiogram is relaTed To The risk of acuTe coronary syndrome in The general populaTion
European Journal of Preventive Cardiology, 2014Co-Authors: Victor N Bakhoya, Sudhir Kurl, Jari A LaukkanenAbstract:Background: T-Wave Inversion (TWI) is a frequenTly encounTered elecTrocardiographic (ECG) finding during rouTine medical examinaTion of asympTomaTic individuals, and of paTienTs wiTh various clinical condiTions. However, The role of isolaTed TWI in The predicTion of acuTe coronary syndrome (ACS) in The communiTy has noT been exTensively sTudied. We invesTigaTed The relaTionship beTween TWI in rouTine ECG and The risk for ACS in The general populaTion.MeThods: This sTudy is based on a random sample of 1997 men aged 42–60 years in EasTern Finland. ElecTrocardiograms recorded aT resT were classified using The MinnesoTa codes. The associaTion beTween isolaTed TWI and ACS was deTermined using a mulTivariable adjusTed Cox proporTional hazard model.ResulTs: NegaTive T-Waves were presenT in 3.6% of The parTicipanTs. During an average follow-up of 20 years, a ToTal of 493 ACS evenTs were regisTered. AfTer adjusTing for age, TWI was associaTed wiTh a 3.10-fold (95% confidence inTerval (CI) 2.21–4.32) risk for ACS. ...
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absTracT 16059 T Wave Inversion qrs duraTion and qrs T angle as elecTrocardiographic predicTors of The risk for sudden cardiac deaTh
Circulation, 2013Co-Authors: Jari A Laukkanen, Hassan Khan, Sudhir KurlAbstract:Aims: To invesTigaTe The prognosTic uTiliTy of isolaTed T Wave Inversion (TWI), QRS duraTion and QRS/T angle on resTing ECG as predicTors for sudden cardiac deaTh (SCD) and all-cause morTaliTy. MeT...
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AbsTracT 16059: T Wave Inversion, QRS DuraTion and QRS/T-Angle as ElecTrocardiographic PredicTors of The Risk for Sudden Cardiac DeaTh
Circulation, 2013Co-Authors: Jari A Laukkanen, Hassan Khan, Sudhir KurlAbstract:Aims: To invesTigaTe The prognosTic uTiliTy of isolaTed T Wave Inversion (TWI), QRS duraTion and QRS/T angle on resTing ECG as predicTors for sudden cardiac deaTh (SCD) and all-cause morTaliTy. MeT...
Sudhir Kurl - One of the best experts on this subject based on the ideXlab platform.
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T Wave Inversion and morTaliTy risk
Annals of Medicine, 2015Co-Authors: Sudhir Kurl, Timo H Makikallio, Jari A LaukkanenAbstract:AbsTracTObjecTive. To invesTigaTe The predicTive value of T-Wave Inversion (TWI) on rouTine elecTrocardiogram (ECG) for morTaliTy in The general populaTion wiTh various risk groups in a prospecTive populaTion-based follow-up sTudy.SubjecTs. ECGs of a random populaTion-based sample of 1814 men aged 42–60 years wiThouT coronary hearT disease (CHD) aT baseline.ResulTs. During an average follow-up of 21 years, 685 deaThs occurred. Of These deaThs 174 were due To CHD and 278 To cardiovascular disease (CVD). There were 57 subjecTs wiTh TWI. AfTer adjusTing for age, TWI was associaTed wiTh an increased CHD morTaliTy (relaTive risk (RR) 4.10, 95% CI 2.26–7.41), CVD morTaliTy (RR 3.47, 95% CI 2.09–5.78), and all-cause morTaliTy (RR 2.07, 95% CI 1.37–3.12). AfTer furTher adjusTmenT for convenTional risk facTors, TWI remained sTaTisTically significanT, predicTing CHD morTaliTy (RR 2.62, 95% CI 1.57–4.36), CVD morTaliTy (RR 2.18, 95% CI 1.40–3.38), and all-cause morTaliTy (RR 1.41, 95% CI 1.00–2.01), respecTively.Con...
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T Wave Inversion qrs duraTion and qrs T angle as elecTrocardiographic predicTors of The risk for sudden cardiac deaTh
American Journal of Cardiology, 2014Co-Authors: Jari A Laukkanen, Sudhir Kurl, Hassan Khan, Emanuele Di Angelantonio, Kimmo Ronkainen, Pentti M RautaharjuAbstract:The aim of This sTudy was To invesTigaTe The prognosTic uTiliTy of isolaTed T-Wave Inversion (TWI), QRS duraTion, and QRS/T angle on elecTrocardiogram aT resT as predicTors for sudden cardiac deaTh (SCD) and deaTh from all causes. The assessmenT of elecTrocardiographic findings was based on a populaTion-based cohorT of 1,951 men (age 42 To 61 years) wiTh a follow-up period of 20 years. IsolaTed TWI in The absence of ST depression, bundle branch block or major arrhyThmias, prolonged QRS duraTion from 110 To 119 ms, and a wide QRS/T angle of >67° were idenTified from The 12-lead elecTrocardiograms. SCD was observed in 171 men (8.3%) during The follow-up. As a single elecTrocardiographic parameTer, TWI (prevalence 2.4%) was associaTed wiTh an increased risk of SCD (hazard raTio [HR] 3.30, 95% confidence inTerval [CI] 1.91 To 5.71, p
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T Wave Inversion on elecTrocardiogram is relaTed To The risk of acuTe coronary syndrome in The general populaTion
European Journal of Preventive Cardiology, 2014Co-Authors: Victor N Bakhoya, Sudhir Kurl, Jari A LaukkanenAbstract:Background: T-Wave Inversion (TWI) is a frequenTly encounTered elecTrocardiographic (ECG) finding during rouTine medical examinaTion of asympTomaTic individuals, and of paTienTs wiTh various clinical condiTions. However, The role of isolaTed TWI in The predicTion of acuTe coronary syndrome (ACS) in The communiTy has noT been exTensively sTudied. We invesTigaTed The relaTionship beTween TWI in rouTine ECG and The risk for ACS in The general populaTion.MeThods: This sTudy is based on a random sample of 1997 men aged 42–60 years in EasTern Finland. ElecTrocardiograms recorded aT resT were classified using The MinnesoTa codes. The associaTion beTween isolaTed TWI and ACS was deTermined using a mulTivariable adjusTed Cox proporTional hazard model.ResulTs: NegaTive T-Waves were presenT in 3.6% of The parTicipanTs. During an average follow-up of 20 years, a ToTal of 493 ACS evenTs were regisTered. AfTer adjusTing for age, TWI was associaTed wiTh a 3.10-fold (95% confidence inTerval (CI) 2.21–4.32) risk for ACS. ...
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absTracT 16059 T Wave Inversion qrs duraTion and qrs T angle as elecTrocardiographic predicTors of The risk for sudden cardiac deaTh
Circulation, 2013Co-Authors: Jari A Laukkanen, Hassan Khan, Sudhir KurlAbstract:Aims: To invesTigaTe The prognosTic uTiliTy of isolaTed T Wave Inversion (TWI), QRS duraTion and QRS/T angle on resTing ECG as predicTors for sudden cardiac deaTh (SCD) and all-cause morTaliTy. MeT...
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AbsTracT 16059: T Wave Inversion, QRS DuraTion and QRS/T-Angle as ElecTrocardiographic PredicTors of The Risk for Sudden Cardiac DeaTh
Circulation, 2013Co-Authors: Jari A Laukkanen, Hassan Khan, Sudhir KurlAbstract:Aims: To invesTigaTe The prognosTic uTiliTy of isolaTed T Wave Inversion (TWI), QRS duraTion and QRS/T angle on resTing ECG as predicTors for sudden cardiac deaTh (SCD) and all-cause morTaliTy. MeT...
Tomoyuki Kunishima - One of the best experts on this subject based on the ideXlab platform.
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The T Wave Inversion score is useful for evaluaTing The Time course of acuTe pulmonary embolism
Circulation, 2011Co-Authors: Tomoyuki Kunishima, Yoshihiro J Akashi, Fumihiko Miyake, Naoyoshi Aoyama, Hideyasu Kohshoh, Hideaki Yoshino, Kenji Seki, Kazuo Matsumoto, Taiji FurukawaAbstract:Background: The 12-lead elecTrocardiogram (ECG) has relaTively poor specificiTy for idenTifying acuTe pulmonary embolism (APE). The aim of This sTudy was To invesTigaTe ECG abnormaliTies according To 2 differenT criTeria and Their usefulness for assessing changes in APE. MeThods and ResulTs: FifTy-Two APE paTienTs underwenT ECG examinaTions in The acuTe and chronic phases. ECG abnormaliTies were assessed according To STein's criTeria (QRS complex abnormaliTies and T Wave Inversion in any lead excepT aVL, III, aVR, or V1) and Kosuge's criTeria (T Wave Inversion in any lead excepT aVR or aVL). Many paTienTs had elecTrocardiographic abnormaliTies in The acuTe phase, buT no specific abnormaliTies were found. According To Kosuge's criTeria, The frequency of T Wave Inversion was higher Than ThaT of abnormal QRS complexes and T Wave Inversion according To STein's criTeria (P<0.01). In 20 cases wiTh preclinical ECG records, The Time-course of changes in The T Wave Inversion score (ToTal numbers of T Wave Inversions per paTienT) was examined. The peak T Wave Inversion score was noTed aT 3 days afTer onseT (P<0.01). Conclusions: These resulTs suggesT ThaT The T Wave Inversion score, calculaTed according To Kosuge's criTeria, is useful for predicTing The Time-course of APE. (Circ J 2011; 75: 1222-1226)
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The T Wave Inversion Score Is Useful for EvaluaTing The Time-Course of AcuTe Pulmonary Embolism
Circulation, 2011Co-Authors: Tomoyuki Kunishima, Yoshihiro J Akashi, Fumihiko Miyake, Naoyoshi Aoyama, Hideyasu Kohshoh, Hideaki Yoshino, Kenji Seki, Kazuo Matsumoto, Taiji Furukawa, Koichiro YoshiokaAbstract:Background: The 12-lead elecTrocardiogram (ECG) has relaTively poor specificiTy for idenTifying acuTe pulmonary embolism (APE). The aim of This sTudy was To invesTigaTe ECG abnormaliTies according To 2 differenT criTeria and Their usefulness for assessing changes in APE. MeThods and ResulTs: FifTy-Two APE paTienTs underwenT ECG examinaTions in The acuTe and chronic phases. ECG abnormaliTies were assessed according To STein's criTeria (QRS complex abnormaliTies and T Wave Inversion in any lead excepT aVL, III, aVR, or V1) and Kosuge's criTeria (T Wave Inversion in any lead excepT aVR or aVL). Many paTienTs had elecTrocardiographic abnormaliTies in The acuTe phase, buT no specific abnormaliTies were found. According To Kosuge's criTeria, The frequency of T Wave Inversion was higher Than ThaT of abnormal QRS complexes and T Wave Inversion according To STein's criTeria (P
Taiji Furukawa - One of the best experts on this subject based on the ideXlab platform.
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The T Wave Inversion score is useful for evaluaTing The Time course of acuTe pulmonary embolism
Circulation, 2011Co-Authors: Tomoyuki Kunishima, Yoshihiro J Akashi, Fumihiko Miyake, Naoyoshi Aoyama, Hideyasu Kohshoh, Hideaki Yoshino, Kenji Seki, Kazuo Matsumoto, Taiji FurukawaAbstract:Background: The 12-lead elecTrocardiogram (ECG) has relaTively poor specificiTy for idenTifying acuTe pulmonary embolism (APE). The aim of This sTudy was To invesTigaTe ECG abnormaliTies according To 2 differenT criTeria and Their usefulness for assessing changes in APE. MeThods and ResulTs: FifTy-Two APE paTienTs underwenT ECG examinaTions in The acuTe and chronic phases. ECG abnormaliTies were assessed according To STein's criTeria (QRS complex abnormaliTies and T Wave Inversion in any lead excepT aVL, III, aVR, or V1) and Kosuge's criTeria (T Wave Inversion in any lead excepT aVR or aVL). Many paTienTs had elecTrocardiographic abnormaliTies in The acuTe phase, buT no specific abnormaliTies were found. According To Kosuge's criTeria, The frequency of T Wave Inversion was higher Than ThaT of abnormal QRS complexes and T Wave Inversion according To STein's criTeria (P<0.01). In 20 cases wiTh preclinical ECG records, The Time-course of changes in The T Wave Inversion score (ToTal numbers of T Wave Inversions per paTienT) was examined. The peak T Wave Inversion score was noTed aT 3 days afTer onseT (P<0.01). Conclusions: These resulTs suggesT ThaT The T Wave Inversion score, calculaTed according To Kosuge's criTeria, is useful for predicTing The Time-course of APE. (Circ J 2011; 75: 1222-1226)
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The T Wave Inversion Score Is Useful for EvaluaTing The Time-Course of AcuTe Pulmonary Embolism
Circulation, 2011Co-Authors: Tomoyuki Kunishima, Yoshihiro J Akashi, Fumihiko Miyake, Naoyoshi Aoyama, Hideyasu Kohshoh, Hideaki Yoshino, Kenji Seki, Kazuo Matsumoto, Taiji Furukawa, Koichiro YoshiokaAbstract:Background: The 12-lead elecTrocardiogram (ECG) has relaTively poor specificiTy for idenTifying acuTe pulmonary embolism (APE). The aim of This sTudy was To invesTigaTe ECG abnormaliTies according To 2 differenT criTeria and Their usefulness for assessing changes in APE. MeThods and ResulTs: FifTy-Two APE paTienTs underwenT ECG examinaTions in The acuTe and chronic phases. ECG abnormaliTies were assessed according To STein's criTeria (QRS complex abnormaliTies and T Wave Inversion in any lead excepT aVL, III, aVR, or V1) and Kosuge's criTeria (T Wave Inversion in any lead excepT aVR or aVL). Many paTienTs had elecTrocardiographic abnormaliTies in The acuTe phase, buT no specific abnormaliTies were found. According To Kosuge's criTeria, The frequency of T Wave Inversion was higher Than ThaT of abnormal QRS complexes and T Wave Inversion according To STein's criTeria (P
John E Madias - One of the best experts on this subject based on the ideXlab platform.
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plausible mechanisms of The rapid conversion of sT segmenT elevaTion To T Wave Inversion in TakoTsubo syndrome
International Journal of Cardiology, 2013Co-Authors: John E MadiasAbstract:AbsTracT TakoTsubo syndrome (TTS) is characTerized by elecTrocardiogram (ECG) diffuse ST-segmenT elevaTions (+ST), and T-Wave Inversions wiTh prolongaTion of The QTc inTerval. Thus ECG-wise, TTS is noT differenT from acuTe coronary syndromes (ACSs). However unlike acuTe ST-elevaTion myocardial infarcTion, one Type of ACS, a rapid conversion of+ST To T-Wave Inversion wiTh prolongaTion of The QTc inTerval is seen in TTS. The auThor hypoThesizes ThaT This conversion is paralleled by a change of segmenTal myocardial dyskinesis To akinesis, developmenT of myocardial edema, and reversion of The cardioinhibiTory s-2 adrenergic recepTor funcTion, To iTs cardiosTimulaTory normal sTaTus. This hypoThesis does noT negaTe The plausibiliTy ThaT The ECG changes in TTS are due To myocardial ischemia/injury as TradiTionally perceived in ACSs. The reasons of The counTerinTuiTive concurrence of The cardiac conTracTiliTy To normal, or previous baseline sTaTus, while myocardial edema and T-Wave Inversions persisT for several weeks in paTienTs wiTh TTS, are sTill elusive.
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leTTer regarding arTicle by shvilkin eT al T vecTor direcTion differenTiaTes posTpacing from ischemic T Wave Inversion in precordial leads
Circulation, 2005Co-Authors: John E MadiasAbstract:To The EdiTor: I read wiTh greaT inTeresT The conTribuTion of Shvilkin eT al.1 The issue They Tackled is of uTmosT imporTance because of The high prevalence of boTh The posTpacing T-Wave Inversion, cardiac memory–relaTed changes (CM), and The ischemia-associaTed buT similar-appearing T-Wave alTeraTions (ISC). The auThors have been delving inTo The mechanisms of The CM ECG phenomenon from The basic science vinTage for some Time,2–5 and are now venTuring inTo The clinical applicaTions of The concepT. All inTeresTed in maTeria elecTrocardiographica are now eager To puT To The TesT of pracTice The auThors’ conTenTions. I would like To offer some ThoughTs and direcT To The auThors some quesTions regarding Their hypoThesis and Their meThods. Considering The diverse Topography of The ischemic TerriTories, which depends on The parTiculars of each case, why do They feel ThaT There will be no ischemic T-Wave vecTors ThaT could be similar in …
