The Experts below are selected from a list of 54 Experts worldwide ranked by ideXlab platform
Duan Guangcai - One of the best experts on this subject based on the ideXlab platform.
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study on fibrinogen related budd chiari syndrome and Takayasus Arteritis
Journal of Henan Medical College for Staff and Workers, 2007Co-Authors: Duan GuangcaiAbstract:Objective To understand the relationship between Budd-Chiari Syndrome(BCS) and inflammatory by analyzing Fibrinogen(Fib) of patients with BCS and Takayasus Arteritis(TA).Methods Examinated Fib of 34 patients with BCS and 16 patients with TA hospitalizing in the department of interventional radiology, collected laboratory reports to run statistical comparing analysis.Results The sample means of Fib of BCS and TA was 2.72 and 4.80,with-4.517 of T value and 0.0003 of P value,having statistical significance.Conclusion The main etiopathogenesis of BCS in China may result from non-inflammatory.
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leucocyte count related budd chiari syndrome and Takayasus Arteritis of a case control study
Central Plains Medical Journal, 2007Co-Authors: Han Xinwei, Chen Chengshi, Duan GuangcaiAbstract:目的 通过对布卡综合征(Budd-Chiari syndrome,BCS)患者和多发性大动脉炎(Takayasus Arteritis,TA)患者白细胞(White Blood Cell,WBC)计数的分析来了解我国BCS与炎症间的关系.方法 对34例BCS患者和16例TA患者计数WBC,收集资料,进行统计学分析.结果 BCS患者的WBC计数和TA患者WBC计数的平均值分别为3.60和9.04,t值为-7.151,P值为0.0001.结论 我国的BCS主要病因可能不是炎症.
Oezer H. - One of the best experts on this subject based on the ideXlab platform.
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Ptpn22 Gene Polymorphism in Takayasus Arteritis
'Oxford University Press (OUP)', 2008Co-Authors: Sahin N., Aksu K., Kamali S., Bicakcigil M., Oezbalkan Z., Oezer H., Akar S., Onat A. M.Abstract:Objective. Takayasus Arteritis (TA) is a chronic, rare granulomatous panArteritis of unknown aetiology involving mainly the aorta and its major branches. In this study, genetic susceptibility to TA has been investigated by screening the functional single nucleotide polymorphism (SNP) of PTPN22 gene encoding the lymphoid-specific protein tyrosine phosphatase. Methods. Totally, 181 patients with TA and 177 healthy controls are genotyped by PCR-RFLP method for the SNP rs2476601 (A/G) of PTPN22 gene. Polymorphic region was amplified by PCR and digested with Xcm I enzyme. Results. Detected frequencies of heterozygous genotype (AG) were 5.1 (9/177) in control group and 3.8 (7/181) in TA group (P = 0.61, odds ratio: 0.75, 95 CI: 0.3, 2.0). No association with angiographic type, vascular involvement or prognosis of TA was observed either. Conclusion. The distribution of PTPN22 polymorphism did not reveal any association with TA in Turkey
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PTPN22 gene polymorphism in Takayasus Arteritis
'Oxford University Press (OUP)', 2008Co-Authors: Sahin N., Aksu K., Kamali S., Bicakcigil M., Oezbalkan Z., Oezer H.Abstract:WOS: 000255315700015PubMed ID: 18375974Objective. Takayasus Arteritis (TA) is a chronic, rare granulomatous panArteritis of unknown aetiology involving mainly the aorta and its major branches. In this study, genetic susceptibility to TA has been investigated by screening the functional single nucleotide polymorphism (SNP) of PTPN22 gene encoding the lymphoid-specific protein tyrosine phosphatase. Methods. Totally, 181 patients with TA and 177 healthy controls are genotyped by PCR-RFLP method for the SNP rs2476601 (A/G) of PTPN22 gene. Polymorphic region was amplified by PCR and digested with Xcm I enzyme. Results. Detected frequencies of heterozygous genotype (AG) were 5.1 (9/177) in control group and 3.8 (7/181) in TA group (P = 0.61, odds ratio: 0.75, 95 CI: 0.3, 2.0). No association with angiographic type, vascular involvement or prognosis of TA was observed either. Conclusion. The distribution of PTPN22 polymorphism did not reveal any association with TA in Turkey
Sahin N. - One of the best experts on this subject based on the ideXlab platform.
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Ptpn22 Gene Polymorphism in Takayasus Arteritis
'Oxford University Press (OUP)', 2008Co-Authors: Sahin N., Aksu K., Kamali S., Bicakcigil M., Oezbalkan Z., Oezer H., Akar S., Onat A. M.Abstract:Objective. Takayasus Arteritis (TA) is a chronic, rare granulomatous panArteritis of unknown aetiology involving mainly the aorta and its major branches. In this study, genetic susceptibility to TA has been investigated by screening the functional single nucleotide polymorphism (SNP) of PTPN22 gene encoding the lymphoid-specific protein tyrosine phosphatase. Methods. Totally, 181 patients with TA and 177 healthy controls are genotyped by PCR-RFLP method for the SNP rs2476601 (A/G) of PTPN22 gene. Polymorphic region was amplified by PCR and digested with Xcm I enzyme. Results. Detected frequencies of heterozygous genotype (AG) were 5.1 (9/177) in control group and 3.8 (7/181) in TA group (P = 0.61, odds ratio: 0.75, 95 CI: 0.3, 2.0). No association with angiographic type, vascular involvement or prognosis of TA was observed either. Conclusion. The distribution of PTPN22 polymorphism did not reveal any association with TA in Turkey
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PTPN22 gene polymorphism in Takayasus Arteritis
'Oxford University Press (OUP)', 2008Co-Authors: Sahin N., Aksu K., Kamali S., Bicakcigil M., Oezbalkan Z., Oezer H.Abstract:WOS: 000255315700015PubMed ID: 18375974Objective. Takayasus Arteritis (TA) is a chronic, rare granulomatous panArteritis of unknown aetiology involving mainly the aorta and its major branches. In this study, genetic susceptibility to TA has been investigated by screening the functional single nucleotide polymorphism (SNP) of PTPN22 gene encoding the lymphoid-specific protein tyrosine phosphatase. Methods. Totally, 181 patients with TA and 177 healthy controls are genotyped by PCR-RFLP method for the SNP rs2476601 (A/G) of PTPN22 gene. Polymorphic region was amplified by PCR and digested with Xcm I enzyme. Results. Detected frequencies of heterozygous genotype (AG) were 5.1 (9/177) in control group and 3.8 (7/181) in TA group (P = 0.61, odds ratio: 0.75, 95 CI: 0.3, 2.0). No association with angiographic type, vascular involvement or prognosis of TA was observed either. Conclusion. The distribution of PTPN22 polymorphism did not reveal any association with TA in Turkey
Onat A. M. - One of the best experts on this subject based on the ideXlab platform.
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Ptpn22 Gene Polymorphism in Takayasus Arteritis
'Oxford University Press (OUP)', 2008Co-Authors: Sahin N., Aksu K., Kamali S., Bicakcigil M., Oezbalkan Z., Oezer H., Akar S., Onat A. M.Abstract:Objective. Takayasus Arteritis (TA) is a chronic, rare granulomatous panArteritis of unknown aetiology involving mainly the aorta and its major branches. In this study, genetic susceptibility to TA has been investigated by screening the functional single nucleotide polymorphism (SNP) of PTPN22 gene encoding the lymphoid-specific protein tyrosine phosphatase. Methods. Totally, 181 patients with TA and 177 healthy controls are genotyped by PCR-RFLP method for the SNP rs2476601 (A/G) of PTPN22 gene. Polymorphic region was amplified by PCR and digested with Xcm I enzyme. Results. Detected frequencies of heterozygous genotype (AG) were 5.1 (9/177) in control group and 3.8 (7/181) in TA group (P = 0.61, odds ratio: 0.75, 95 CI: 0.3, 2.0). No association with angiographic type, vascular involvement or prognosis of TA was observed either. Conclusion. The distribution of PTPN22 polymorphism did not reveal any association with TA in Turkey
Aksu K. - One of the best experts on this subject based on the ideXlab platform.
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Ptpn22 Gene Polymorphism in Takayasus Arteritis
'Oxford University Press (OUP)', 2008Co-Authors: Sahin N., Aksu K., Kamali S., Bicakcigil M., Oezbalkan Z., Oezer H., Akar S., Onat A. M.Abstract:Objective. Takayasus Arteritis (TA) is a chronic, rare granulomatous panArteritis of unknown aetiology involving mainly the aorta and its major branches. In this study, genetic susceptibility to TA has been investigated by screening the functional single nucleotide polymorphism (SNP) of PTPN22 gene encoding the lymphoid-specific protein tyrosine phosphatase. Methods. Totally, 181 patients with TA and 177 healthy controls are genotyped by PCR-RFLP method for the SNP rs2476601 (A/G) of PTPN22 gene. Polymorphic region was amplified by PCR and digested with Xcm I enzyme. Results. Detected frequencies of heterozygous genotype (AG) were 5.1 (9/177) in control group and 3.8 (7/181) in TA group (P = 0.61, odds ratio: 0.75, 95 CI: 0.3, 2.0). No association with angiographic type, vascular involvement or prognosis of TA was observed either. Conclusion. The distribution of PTPN22 polymorphism did not reveal any association with TA in Turkey
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PTPN22 gene polymorphism in Takayasus Arteritis
'Oxford University Press (OUP)', 2008Co-Authors: Sahin N., Aksu K., Kamali S., Bicakcigil M., Oezbalkan Z., Oezer H.Abstract:WOS: 000255315700015PubMed ID: 18375974Objective. Takayasus Arteritis (TA) is a chronic, rare granulomatous panArteritis of unknown aetiology involving mainly the aorta and its major branches. In this study, genetic susceptibility to TA has been investigated by screening the functional single nucleotide polymorphism (SNP) of PTPN22 gene encoding the lymphoid-specific protein tyrosine phosphatase. Methods. Totally, 181 patients with TA and 177 healthy controls are genotyped by PCR-RFLP method for the SNP rs2476601 (A/G) of PTPN22 gene. Polymorphic region was amplified by PCR and digested with Xcm I enzyme. Results. Detected frequencies of heterozygous genotype (AG) were 5.1 (9/177) in control group and 3.8 (7/181) in TA group (P = 0.61, odds ratio: 0.75, 95 CI: 0.3, 2.0). No association with angiographic type, vascular involvement or prognosis of TA was observed either. Conclusion. The distribution of PTPN22 polymorphism did not reveal any association with TA in Turkey