The Experts below are selected from a list of 1812 Experts worldwide ranked by ideXlab platform
Xiaodong Jia - One of the best experts on this subject based on the ideXlab platform.
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Tunable Functionalization of Saturated C-C and C-H Bonds of N,N'-Diarylpiperazines Enabled by tert-Butyl Nitrite (TBN) and NaNO2 Systems.
Organic letters, 2019Co-Authors: Ting Zhang, Shuwei Zhang, Zheng Sun, Yuxian Zhang, Yu Yuan, Xiaodong JiaAbstract:A tunable functionalization of saturated C–C and C–H bonds of N,N′-diarylpiperazine derivatives was realized by tert-butyl nitrite (TBN) and NaNO2 systems, respectively. When TBN was employed as th...
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TBN as a metal free reagent initiated sp3 c h functionalization of glycine esters synthesis of quinoline 2 carboxylate esters
Tetrahedron Letters, 2018Co-Authors: Xiaofei Liu, Xiaodong Jia, Yu Yuan, Yu ShaoAbstract:Abstract As a metal-free reagent, tert-butylnitrite (TBN) initiated aerobic sp3 C–H bond oxidation of glycine esters was achieved, providing a series of quinoline-2-carboxylates in good yields. The mechanistic investigation revealed that in the presence of molecular oxygen, TBN derived radicals were involved in the C–H bond oxidation and the terminal aromatization.
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tert-Butyl Nitrite (TBN) as a Versatile Reagent in Organic Synthesis
Synthesis, 2017Co-Authors: Xiaodong JiaAbstract:tert -Butyl nitrite (TBN) is an important metal-free reagent that is widely applied in various organic transformations. Besides its traditional applications in nitrosation and diazotization, its ability to activate molecular oxygen to enable the initiation of radical reactions, including nitration, oximation, oxidation, and so on, has attracted extensively attention in the past decade. This review highlights recent advances in this field to promote further exploration of this versatile compound. 1 Introduction 2 Reactions Involving TBN 2.1 Nitrosation 2.2 Oximation 2.3 Diazotization 2.4 Nitration 2.5 Oxidation 2.6 Other Reactions 3 Conclusion and Perspective
Bhalchandra M. Bhanage - One of the best experts on this subject based on the ideXlab platform.
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tert-Butyl Nitrite-Mediated Synthesis of N-Nitrosoamides, Carboxylic Acids, Benzocoumarins, and Isocoumarins from Amides
The Journal of organic chemistry, 2017Co-Authors: Subhash L. Yedage, Bhalchandra M. BhanageAbstract:This work reports tert-butyl nitrite (TBN) as a multitask reagent for (1) the controlled synthesis of N-nitrosoamide from N-alkyl amides, (2) hydrolysis of N-methoxyamides to carboxylic acids, (3) metal- and oxidant-free benzocoumarin synthesis from ortho-aryl-N-methoxyamides via N-H, C-N, and C-H bond activation, and (4) isocoumarin synthesis using Ru(II)/PEG as a recyclable catalytic system via ortho-C-H activation and TBN as an oxygen source. The sequential functional group interconversion of amide to acid has also been examined using IR spectroscopic analysis. Additionally, this methodology is highly advantageous due to short reaction time, gram scale synthesis, and broad substrate scope.
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tert-Butyl Nitrite-Mediated Synthesis of N‑Nitrosoamides, Carboxylic Acids, Benzocoumarins, and Isocoumarins from Amides
2017Co-Authors: Subhash L. Yedage, Bhalchandra M. BhanageAbstract:This work reports tert-butyl nitrite (TBN) as a multitask reagent for (1) the controlled synthesis of N-nitrosoamide from N-alkyl amides, (2) hydrolysis of N-methoxyamides to carboxylic acids, (3) metal- and oxidant-free benzocoumarin synthesis from ortho-aryl-N-methoxyamides via N–H, C–N, and C–H bond activation, and (4) isocoumarin synthesis using Ru(II)/PEG as a recyclable catalytic system via ortho-C–H activation and TBN as an oxygen source. The sequential functional group interconversion of amide to acid has also been examined using IR spectroscopic analysis. Additionally, this methodology is highly advantageous due to short reaction time, gram scale synthesis, and broad substrate scope
Yuliyanto Dwi - One of the best experts on this subject based on the ideXlab platform.
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PENGARUH JENIS BAHAN BAKAR TERHADAP VISKOSITAS DAN TBN PELUMAS SAE10W-30 PADA MOTOR BAKAR 125CC
2018Co-Authors: Yuliyanto DwiAbstract:Seiring bertambah majunya pengembangan jenis bahan bakar bensin memunculkan banyak jenis bahan bakar bensin yang dijual di Indonesia untuk memenuhi permintaan konsumen yang dibutuhkan untuk energi bahan bakar motor bakar. Meliputi jenis bahan bakar Premium, Pertalite, Pertamax, Pertamax Turbo, dan Pertamax Racing. Oleh karena itu dengan banyaknya pilihan tersebut dilakukanlah penelitian terhadap penggunaan 3 jenis bahan bakar yang berbeda yaitu: Premium, Pertalite, dan Pertamax yang diuji pada mesin motor bakar 125cc selama 7 jam nonstop pada kecepatan 4000 Rpm untuk diketahui pengaruhnya terhadap perbedaan penurunan nilai Viskositas dan TBN minyak pelumas SAE 10W-30 yang digunakan pada mesin motor bakar tersebut, Mengingat fungsi Minyak pelumas juga sangat penting dalam menjaga keawetan dan kinerja mesin. Hasil penelitian menunjukkan penggunaan bahan bakar Pertamax memiliki penurunan nilai Viskositas dan TBN tertinggi dibanding dengan bahan bakar Pertalite dan Premium. Dimana masing-masing nilai Viskositas dan TBN pada sampel minyak pelumas Pertamax 9,7 cSt dan 6,9 mg KOH/g. Pertalite 9,8 cSt dan 7,1 mg KOH/g. Premium 7,2 cSt dan 10 mg KOH/g
Subhash L. Yedage - One of the best experts on this subject based on the ideXlab platform.
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tert-Butyl Nitrite-Mediated Synthesis of N-Nitrosoamides, Carboxylic Acids, Benzocoumarins, and Isocoumarins from Amides
The Journal of organic chemistry, 2017Co-Authors: Subhash L. Yedage, Bhalchandra M. BhanageAbstract:This work reports tert-butyl nitrite (TBN) as a multitask reagent for (1) the controlled synthesis of N-nitrosoamide from N-alkyl amides, (2) hydrolysis of N-methoxyamides to carboxylic acids, (3) metal- and oxidant-free benzocoumarin synthesis from ortho-aryl-N-methoxyamides via N-H, C-N, and C-H bond activation, and (4) isocoumarin synthesis using Ru(II)/PEG as a recyclable catalytic system via ortho-C-H activation and TBN as an oxygen source. The sequential functional group interconversion of amide to acid has also been examined using IR spectroscopic analysis. Additionally, this methodology is highly advantageous due to short reaction time, gram scale synthesis, and broad substrate scope.
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tert-Butyl Nitrite-Mediated Synthesis of N‑Nitrosoamides, Carboxylic Acids, Benzocoumarins, and Isocoumarins from Amides
2017Co-Authors: Subhash L. Yedage, Bhalchandra M. BhanageAbstract:This work reports tert-butyl nitrite (TBN) as a multitask reagent for (1) the controlled synthesis of N-nitrosoamide from N-alkyl amides, (2) hydrolysis of N-methoxyamides to carboxylic acids, (3) metal- and oxidant-free benzocoumarin synthesis from ortho-aryl-N-methoxyamides via N–H, C–N, and C–H bond activation, and (4) isocoumarin synthesis using Ru(II)/PEG as a recyclable catalytic system via ortho-C–H activation and TBN as an oxygen source. The sequential functional group interconversion of amide to acid has also been examined using IR spectroscopic analysis. Additionally, this methodology is highly advantageous due to short reaction time, gram scale synthesis, and broad substrate scope
Jeyakumar Kandasamy - One of the best experts on this subject based on the ideXlab platform.
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an efficient synthesis of n nitrosamines under solvent metal and acid free conditions using tert butyl nitrite
Green Chemistry, 2016Co-Authors: Priyanka Chaudhary, Shahulhameed Sabiah, Nalluchamy Muniyappan, Surabhi Gupta, Jeyakumar KandasamyAbstract:Synthesis of various N-nitroso compounds from secondary amines is reported using tert-butyl nitrite (TBN) under solvent free conditions. Broad substrate scope, metal and acid free conditions, easy isolation procedure and excellent yields are few important features of this methodology. The acid labile protecting groups such as tert-butyldimethylsilyl (TBDMS) and tert-butyloxycarbonyl (Boc) as well as sensitive functional groups such as phenols, olefins and alkynes are found to be stable under the standard reaction conditions. Besides N-nitrosation, TBN is also found to be an efficient reagent in few other transformations including aryl hydrazines to aryl azides and primary amides to carboxylic acids under mild conditions.
