The Experts below are selected from a list of 183 Experts worldwide ranked by ideXlab platform
John Turnbull - One of the best experts on this subject based on the ideXlab platform.
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Temporal Arteritis and polymyalgia rheumatica: Nosographic and nosologic considerations
Neurology, 1996Co-Authors: John TurnbullAbstract:Original reports on Temporal Arteritis and polymyalgia rheumatica were reviewed before and after the introduction of steroid therapy to prevent blindness in Temporal Arteritis.In some cases, the original data were reworked. There is evidence that both diseases have become more benign. As a result, the perceived risk of blindness is presently overestimated, as is the perceived benefit of steroids in reducing this risk, and neither should be used as support for an essential difference between Temporal Arteritis and polymyalgia rheumatica. Indeed, no qualitative differences otherwise exist and both are best viewed as facets of a common disease spectrum with variable risk of adverse outcome. Some of the difficulties in dealing with diseases characterized by variable risk within present dichotomous classifications are discussed. It is likely that in many patients benign disease is presently undiagnosed. It is likely that certain classifications of Temporal Arteritis and polymyalgia rheumatica now in use lead to an overtreatment of some patients with relatively benign disease. NEUROLOGY 1996;46: 901-906
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Temporal Arteritis and polymyalgia rheumatica: Nosographic and nosologic considerations
Neurology, 1996Co-Authors: John TurnbullAbstract:Original reports on Temporal Arteritis and polymyalgia rheumatica were reviewed before and after the introduction of steroid therapy to prevent blindness in Temporal Arteritis.In some cases, the original data were reworked. There is evidence that both diseases have become more benign. As a result, the perceived risk of blindness is presently overestimated, as is the perceived benefit of steroids in reducing this risk, and neither should be used as support for an essential difference between Temporal Arteritis and polymyalgia rheumatica. Indeed, no qualitative differences otherwise exist and both are best viewed as facets of a common disease spectrum with variable risk of adverse outcome. Some of the difficulties in dealing with diseases characterized by variable risk within present dichotomous classifications are discussed. It is likely that in many patients benign disease is presently undiagnosed. It is likely that certain classifications of Temporal Arteritis and polymyalgia rheumatica now in use lead to an overtreatment of some patients with relatively benign disease. NEUROLOGY 1996;46: 901-906
James D. Harrover - One of the best experts on this subject based on the ideXlab platform.
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Polymyalgia Rheumatica and Temporal Arteritis
American Family Physician, 2000Co-Authors: Ted Epperly, Kevin E. Moore, James D. HarroverAbstract:Polymyalgia rheumatica and Temporal Arteritis are closely related inflammatory conditions that affect different cellular targets in genetically predisposed persons. Compared with Temporal Arteritis, polymyalgla rheumatica is much more common, affecting one in 200 persons older than 50 years. Temporal Arteritis, however, is more dangerous and can lead to sudden blindness. The diagnosis of polymyalgia rheumatica is based on the presence of a clinical syndrome consisting of fever, nonspecific somatic complaints, pain and stiffness in the shoulder and pelvic girdles, and an elevated erythrocyte sedimentation rate. Temporal Arteritis typically presents with many of the same findings as polymyalgia rheumatica, but patients also have headaches and tenderness to palpation over the involved artery. Arterial biopsy usually confirms the diagnosis of Temporal Arteritis. Early diagnosis and treatment of polymyalgia rheumatica or Temporal Arteritis can dramatically improve patients' lives and return them to previous functional status. Corticosteroid therapy provides rapid and dramatic improvement of the clinical features of both conditions. Therapy is generally continued for six to 24 months. Throughout treatment, clinical condition is assessed periodically. Patients are instructed to see their physician immediately if symptoms recur or they develop new headache, jaw claudication or visual problems.
Theodore G. Ganiats - One of the best experts on this subject based on the ideXlab platform.
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Temporal Arteritis with normal erythrocyte sedimentation rate.
The Journal of the American Board of Family Practice, 1991Co-Authors: Theodore G. GaniatsAbstract:The erythrocyte sedimentation rate (ESR) is used to differentiate Temporal Arteritis from other forms of headache in the elderly. Though Temporal Arteritis can occur with a normal ESR, this is not generally appreciated in primary care. The case reported here is a 74-year-old woman with biopsy-proven Temporal Arteritis; her ESR was 22 mm/hr. Of note, her hematocrit was more than 40 percent, a condition previously reported to be associated with Temporal Arteritis and a normal ESR. This discussion focuses on the diagnosis of Temporal Arteritis and its associated symptoms.
Kevin M Mcknight - One of the best experts on this subject based on the ideXlab platform.
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Temporal Arteritis with low erythrocyte sedimentation rate a review of five cases
Arthritis & Rheumatism, 2010Co-Authors: Christopher M Wise, Carlos A Agudelo, Walter L Chmelewski, Kevin M McknightAbstract:We compared 5 patients who had biopsy-proven Temporal Arteritis and erythrocyte sedimentation rates (ESR) less than 50 mm/hour with 25 patients who had Temporal Arteritis and high ESR and with 10 patients who had negative Temporal artery biopsy results and low ESR. Patients with low-ESR Temporal Arteritis were similar to the other groups, except that they had a higher mean hemoglobin level than the high-ESR group and a significant increase in the percentage of patients (4 of 5) who had a previous diagnosis of polymyalgia rheumatica or had received steroid therapy compared with either of the other groups. The latter finding suggests that even low-dose steroid therapy can lower the ESR in patients with Temporal Arteritis. We conclude that the ESR is low in only a small percentage of patients with Temporal Arteritis, and that most of these patients have a history of polymyalgia rheumatica or steroid therapy.
Ted Epperly - One of the best experts on this subject based on the ideXlab platform.
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Polymyalgia Rheumatica and Temporal Arteritis
American Family Physician, 2000Co-Authors: Ted Epperly, Kevin E. Moore, James D. HarroverAbstract:Polymyalgia rheumatica and Temporal Arteritis are closely related inflammatory conditions that affect different cellular targets in genetically predisposed persons. Compared with Temporal Arteritis, polymyalgla rheumatica is much more common, affecting one in 200 persons older than 50 years. Temporal Arteritis, however, is more dangerous and can lead to sudden blindness. The diagnosis of polymyalgia rheumatica is based on the presence of a clinical syndrome consisting of fever, nonspecific somatic complaints, pain and stiffness in the shoulder and pelvic girdles, and an elevated erythrocyte sedimentation rate. Temporal Arteritis typically presents with many of the same findings as polymyalgia rheumatica, but patients also have headaches and tenderness to palpation over the involved artery. Arterial biopsy usually confirms the diagnosis of Temporal Arteritis. Early diagnosis and treatment of polymyalgia rheumatica or Temporal Arteritis can dramatically improve patients' lives and return them to previous functional status. Corticosteroid therapy provides rapid and dramatic improvement of the clinical features of both conditions. Therapy is generally continued for six to 24 months. Throughout treatment, clinical condition is assessed periodically. Patients are instructed to see their physician immediately if symptoms recur or they develop new headache, jaw claudication or visual problems.
