The Experts below are selected from a list of 810 Experts worldwide ranked by ideXlab platform
Soiderer, Emily E. - One of the best experts on this subject based on the ideXlab platform.
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Bilateral flexor Tendon Contracture following onychectomy in 2 cats
2005Co-Authors: Cooper, Maureen A., Laverty, Peter H., Soiderer, Emily E.Abstract:Two cats presented with bilateral flexor Tendon Contracture following onychectomy. This previously unreported complication proved to be painful and debilitating. Deep digital flexor tenectomy successfully resolved the problem. Twelve months after surgery, the first cat remains free of complications. The second cat recovered full limb function, but died of unrelated causes
Cooper, Maureen A. - One of the best experts on this subject based on the ideXlab platform.
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Bilateral flexor Tendon Contracture following onychectomy in 2 cats
2005Co-Authors: Cooper, Maureen A., Laverty, Peter H., Soiderer, Emily E.Abstract:Two cats presented with bilateral flexor Tendon Contracture following onychectomy. This previously unreported complication proved to be painful and debilitating. Deep digital flexor tenectomy successfully resolved the problem. Twelve months after surgery, the first cat remains free of complications. The second cat recovered full limb function, but died of unrelated causes
Laverty, Peter H. - One of the best experts on this subject based on the ideXlab platform.
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Bilateral flexor Tendon Contracture following onychectomy in 2 cats
2005Co-Authors: Cooper, Maureen A., Laverty, Peter H., Soiderer, Emily E.Abstract:Two cats presented with bilateral flexor Tendon Contracture following onychectomy. This previously unreported complication proved to be painful and debilitating. Deep digital flexor tenectomy successfully resolved the problem. Twelve months after surgery, the first cat remains free of complications. The second cat recovered full limb function, but died of unrelated causes
Boris Matev - One of the best experts on this subject based on the ideXlab platform.
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myogenic fibrosis of the flexor Tendons after amphetamine drug abuse
2019Co-Authors: Stefan Tserovski, Simona Georgieva, Desislava Bogdanova, Boris MatevAbstract:Myogenic fibrosis of the flexor Tendons in a 23-year-old patient was caused by intense drug abuse. He was presented in the clinic with spastic flexor Tendon Contracture of his right hand. The patient was treated by Tendon elongation with a satisfactory result. The treatment of flexor Tendon Contracture in those cases is very difficult and needs to be done in a complex way.
Nonhlanhla P Khumalo - One of the best experts on this subject based on the ideXlab platform.
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mutations in fam111b cause hereditary fibrosing poikiloderma with Tendon Contracture myopathy and pulmonary fibrosis
2013Co-Authors: Sandra Mercier, N. Bodak, Sebastien Kury, Gasnat Shaboodien, Darren T Houniet, Nonhlanhla P Khumalo, Chantal Bouhanna, Valerie Cormierdaire, Albert David, Laurence FaivreAbstract:Congenital poikiloderma is characterized by a combination of mottled pigmentation, telangiectasia, and epidermal atrophy in the first few months of life. We have previously described a South African European-descent family affected by a rare autosomal-dominant form of hereditary fibrosing poikiloderma accompanied by Tendon Contracture, myopathy, and pulmonary fibrosis. Here, we report the identification of causative mutations in FAM111B by whole-exome sequencing. In total, three FAM111B missense mutations were identified in five kindreds of different ethnic backgrounds. The mutation segregated with the disease in one large pedigree, and mutations were de novo in two other pedigrees. All three mutations were absent from public databases and were not observed on Sanger sequencing of 388 ethnically matched control subjects. The three single-nucleotide mutations code for amino acid changes that are clustered within a putative trypsin-like cysteine/serine peptidase domain of FAM111B. These findings provide evidence of the involvement of FAM111B in congenital poikiloderma and multisystem fibrosis.
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Poikiloderma, Tendon Contracture and pulmonary fibrosis: a new autosomal dominant syndrome?
2006Co-Authors: Nonhlanhla P Khumalo, Bongani M. Mayosi, Komala Pillay, Peter Beighton, H C Wainwright, B. Walker, N. Saxe, E.d. BatemanAbstract:Summary Members of two generations of a South African family have a unique syndrome comprising poikiloderma, Tendon Contractures and progressive pulmonary fibrosis. The condition is clinically important as the skin changes, which involve the face, have considerable cosmetic impact, while lung involvement is potentially lethal in adulthood. Skin manifestations which facilitate diagnosis include facial telangiectasia, mottled hypo- and hyperpigmentation, papules and epidermal atrophy. The scalp, facial and body hair are fine and scanty. The Tendon Contractures lead to progressive digital flexion deformities and abnormalities of the ankles and feet, with disturbance of gait. Pulmonary involvement manifests as progressive dyspnoea. Pedigree data are compatible with an autosomal dominant mode of transmission. Poikiloderma of Weary is characterized by linear sclerotic and fibrous bands and not Tendon Contractures and is not associated with potentially lethal pulmonary fibrosis. Rather than name this disorder a variant of Weary syndrome, it might be prudent to use as an umbrella title one composed by Weary himself: ‘hereditary sclerosing poikiloderma’ (HSP), under which variants such as HSP Weary type, HSP with cardiac involvement (aortic stenosis described as inconsistently associated with Weary syndrome) and HSP with Tendon/pulmonary involvement (current family) may be classified. The manifestations in this family differ from other poikilodermata and, to the best of our knowledge, have not been previously documented.
