The Experts below are selected from a list of 207 Experts worldwide ranked by ideXlab platform

Anton D??berl - One of the best experts on this subject based on the ideXlab platform.

  • Recurrent Tension Headache in Adolescents Treated with Self???Help Relaxation Training and a Muscle Relaxant Drug
    Headache: The Journal of Head and Face Pain, 1990
    Co-Authors: Bo Larsson, Lennart Melin, Anton D??berl
    Abstract:

    Forty-eight adolescents suffering from recurrent Tension Headache participated in a controlled trial conducted in a high school setting. During the first treatment phase self-help relaxation training was compared with a waiting-list group. Following this phase a pharmacological regimen consisting of a muscle relaxant (chlormezanone) and placebo was superimposed on relaxation therapy in a double-blind crossover design. Each treatment phase encompassed a 5-week period. In addition to the evaluation of Headache complaints, psychological distress among students was measured with respect to their experience of somatic complaints, depressive, anxiety and stress symptoms. Although self-help relaxation training significantly decreased the severity and annoyance of adolescents' Headache besides their somatic complaints, the clinical improvement of Headache was modest. The addition of chlormezanone did not help those who were nonresponders to self-help relaxation training. Finally, a set of pretreatment variables consisting of baseline Headache severity and annoyance, experience of anxiety and daily life stress among adolescents could predict outcome of self-help relaxation therapy.

Ottar Sjaastad - One of the best experts on this subject based on the ideXlab platform.

  • Tension Headache botulinum toxin paralysis of temporal muscles
    Headache, 1994
    Co-Authors: Johnanker Zwart, Gunnar Bovim, Trond Sand, Ottar Sjaastad
    Abstract:

    SYNOPSIS The pathogenetic mechanism of Tension Headache (TH) is still unknown. The role of pericranial muscle Tension in TH is also enigmatic. To evaluate this factor in chronic TH, pericranial muscles were paralysed in 6 chronic TH patients, using botulinum toxin. All patients fulfilled the IHS criteria of chronic TH associated with involvement of the pericranial muscles, but not the current criteria for cervicogenic Headache. The patients were followed-up regularly with evaluation of the paralysis, changes in pain intensity, and pressure pain threshold measurements. We primarily only injected the temporal muscle on the one side, using the other side as a control. Contralateral muscles were in some cases injected at a later stage. In our study, we did not find any significant reduction in pain intensity, as measured by the visual analogue scale, nor any changes in pressure pain threshold, as measured by an algometer. On the basis of our observations, we conclude that muscle Tension in these muscles possibly plays a minor role in the genesis of chronic TH. In our study, however, we have only treated a limited number of patients, and only one pericranial muscle has been injected systematically. Further studies of various neck/posterior head muscles ought to be performed in order to further evaluate a possible effect of Tension in the pericranial musculature in producing this type of pain.

Bo Larsson - One of the best experts on this subject based on the ideXlab platform.

  • Recurrent Tension Headache in Adolescents Treated with Self???Help Relaxation Training and a Muscle Relaxant Drug
    Headache: The Journal of Head and Face Pain, 1990
    Co-Authors: Bo Larsson, Lennart Melin, Anton D??berl
    Abstract:

    Forty-eight adolescents suffering from recurrent Tension Headache participated in a controlled trial conducted in a high school setting. During the first treatment phase self-help relaxation training was compared with a waiting-list group. Following this phase a pharmacological regimen consisting of a muscle relaxant (chlormezanone) and placebo was superimposed on relaxation therapy in a double-blind crossover design. Each treatment phase encompassed a 5-week period. In addition to the evaluation of Headache complaints, psychological distress among students was measured with respect to their experience of somatic complaints, depressive, anxiety and stress symptoms. Although self-help relaxation training significantly decreased the severity and annoyance of adolescents' Headache besides their somatic complaints, the clinical improvement of Headache was modest. The addition of chlormezanone did not help those who were nonresponders to self-help relaxation training. Finally, a set of pretreatment variables consisting of baseline Headache severity and annoyance, experience of anxiety and daily life stress among adolescents could predict outcome of self-help relaxation therapy.

Johnanker Zwart - One of the best experts on this subject based on the ideXlab platform.

  • Tension Headache botulinum toxin paralysis of temporal muscles
    Headache, 1994
    Co-Authors: Johnanker Zwart, Gunnar Bovim, Trond Sand, Ottar Sjaastad
    Abstract:

    SYNOPSIS The pathogenetic mechanism of Tension Headache (TH) is still unknown. The role of pericranial muscle Tension in TH is also enigmatic. To evaluate this factor in chronic TH, pericranial muscles were paralysed in 6 chronic TH patients, using botulinum toxin. All patients fulfilled the IHS criteria of chronic TH associated with involvement of the pericranial muscles, but not the current criteria for cervicogenic Headache. The patients were followed-up regularly with evaluation of the paralysis, changes in pain intensity, and pressure pain threshold measurements. We primarily only injected the temporal muscle on the one side, using the other side as a control. Contralateral muscles were in some cases injected at a later stage. In our study, we did not find any significant reduction in pain intensity, as measured by the visual analogue scale, nor any changes in pressure pain threshold, as measured by an algometer. On the basis of our observations, we conclude that muscle Tension in these muscles possibly plays a minor role in the genesis of chronic TH. In our study, however, we have only treated a limited number of patients, and only one pericranial muscle has been injected systematically. Further studies of various neck/posterior head muscles ought to be performed in order to further evaluate a possible effect of Tension in the pericranial musculature in producing this type of pain.

Catherine C Turkel - One of the best experts on this subject based on the ideXlab platform.

  • botulinum toxin type a in the prophylactic treatment of chronic Tension type Headache a multicentre double blind randomized placebo controlled parallel group study
    Cephalalgia, 2006
    Co-Authors: Stephen D Silberstein, H Gobel, R Jensen, Arthur H Elkind, Ronald E Degryse, J M C M Walcott, Catherine C Turkel
    Abstract:

    We studied the safety and efficacy of 0 U, 50 U, 100 U, 150 U (five sites), 86 Usub and 100 Usub (three sites) botulinum toxin type A (BoNTA; BOTOX®; Allergan, Inc., Irvine, CA, USA) for the prophylaxis of chronic Tension-type Headache (CTTH). Three hundred patients (62.3± female; mean age 42.6 years) enrolled. For the primary endpoint, the mean change from baseline in the number of TTH-free days per month, there was no statistically significant difference between placebo and four BoNTA groups, but a significant difference favouring placebo vs. BoNTA 150 was observed (4.5 vs. 2.8 Tension Headache-free days/month; P = 0.007). All treatment groups improved at day 60. Although efficacy was not demonstrated for the primary endpoint, at day 90, more patients in three BoNTA groups had ≥50± decrease in Tension Headache days than did placebo (P ≤ 0.024). Most treatment-related adverse events were mild or moderate, and transient. BoNTA was safe and well-tolerated in the study.