The Experts below are selected from a list of 1197906 Experts worldwide ranked by ideXlab platform
T. Shimizu - One of the best experts on this subject based on the ideXlab platform.
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Short and long Term Analysis of heart rate variations in spontaneously hypertensive rats: effects of DSP-4 administration.
Biomedicine & Pharmacotherapy, 2005Co-Authors: H. Kawamura, H. Mitsubayashi, T. Miao, T. ShimizuAbstract:The purpose of this study was to investigate whether or not central noradrenergic neurons were involved in the time structure of circadian variation of heart rate (HR) in hypertension. We used spontaneously hypertensive rats (SHR Izm ) and normotensive controls (Wistar Kyoto rats, WKY Izm ). We selectively destroyed the noradrenergic neurons in the central nervous system (CNS) by administering noradrenergic neurotoxin, N-(2-chloroethy)-N-ethyl-2-bromobenzylamine (DSP4). Frequency domain measures of variation of HR (VHR) were obtained using the maximum entropy method. The 24-h time frame in VHR is usually dominant in both SHR Izm and WKY Izm . Fourteen days after the administering of DSP4, the mean 24-h systolic arterial pressure (SAP) remained higher in SHR Izm than in WKY Izm . After chemical lesion, ultradian rhythms (12-, 8-, 6-, and 4-h periods) in VHR became more remarkable in both SHR Izm and WKY Izm than before chemical lesion. Before chemical lesion, an inverse relationship existed between frequency and power spectral density in VHR, demonstrating 1/fβ characteristics. The slope of 1/f β in VHR did not differ between SHR Izm and WKY Izm . After the chemical lesion it did not also differ from that of each strain in control period (before lesion). Therefore, the noradrenergic neurons may not affect the time structure of HR in SHR Izm and WKY Izm for short-Term time Analysis. However, the intact noradrenergic neurons in CNS may be important to keep normal cardiac autonomic function in SHR Izm for long-Term Analysis.
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Short and long Term Analysis of heart rate variations in spontaneously hypertensive rats: effects of DSP-4 administration.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2005Co-Authors: H. Kawamura, H. Mitsubayashi, T. Miao, T. ShimizuAbstract:The purpose of this study was to investigate whether or not central noradrenergic neurons were involved in the time structure of circadian variation of heart rate (HR) in hypertension. We used spontaneously hypertensive rats (SHR(Izm)) and normotensive controls (Wistar Kyoto rats, WKY(Izm)). We selectively destroyed the noradrenergic neurons in the central nervous system (CNS) by administering noradrenergic neurotoxin, N-(2-chloroethy)-N-ethyl-2-bromobenzylamine (DSP4). Frequency domain measures of variation of HR (VHR) were obtained using the maximum entropy method. The 24-h time frame in VHR is usually dominant in both SHR(Izm) and WKY(Izm). Fourteen days after the administering of DSP4, the mean 24-h systolic arterial pressure (SAP) remained higher in SHR(Izm) than in WKY(Izm). After chemical lesion, ultradian rhythms (12-, 8-, 6-, and 4-h periods) in VHR became more remarkable in both SHR(Izm) and WKY(Izm) than before chemical lesion. Before chemical lesion, an inverse relationship existed between frequency and power spectral density in VHR, demonstrating 1/f(beta) characteristics. The slope of 1/f(beta) in VHR did not differ between SHR(Izm) and WKY(Izm). After the chemical lesion it did not also differ from that of each strain in control period (before lesion). Therefore, the noradrenergic neurons may not affect the time structure of HR in SHR(Izm) and WKY(Izm) for short-Term time Analysis. However, the intact noradrenergic neurons in CNS may be important to keep normal cardiac autonomic function in SHR(Izm) for long-Term Analysis.
H. Kawamura - One of the best experts on this subject based on the ideXlab platform.
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Short and long Term Analysis of heart rate variations in spontaneously hypertensive rats: effects of DSP-4 administration.
Biomedicine & Pharmacotherapy, 2005Co-Authors: H. Kawamura, H. Mitsubayashi, T. Miao, T. ShimizuAbstract:The purpose of this study was to investigate whether or not central noradrenergic neurons were involved in the time structure of circadian variation of heart rate (HR) in hypertension. We used spontaneously hypertensive rats (SHR Izm ) and normotensive controls (Wistar Kyoto rats, WKY Izm ). We selectively destroyed the noradrenergic neurons in the central nervous system (CNS) by administering noradrenergic neurotoxin, N-(2-chloroethy)-N-ethyl-2-bromobenzylamine (DSP4). Frequency domain measures of variation of HR (VHR) were obtained using the maximum entropy method. The 24-h time frame in VHR is usually dominant in both SHR Izm and WKY Izm . Fourteen days after the administering of DSP4, the mean 24-h systolic arterial pressure (SAP) remained higher in SHR Izm than in WKY Izm . After chemical lesion, ultradian rhythms (12-, 8-, 6-, and 4-h periods) in VHR became more remarkable in both SHR Izm and WKY Izm than before chemical lesion. Before chemical lesion, an inverse relationship existed between frequency and power spectral density in VHR, demonstrating 1/fβ characteristics. The slope of 1/f β in VHR did not differ between SHR Izm and WKY Izm . After the chemical lesion it did not also differ from that of each strain in control period (before lesion). Therefore, the noradrenergic neurons may not affect the time structure of HR in SHR Izm and WKY Izm for short-Term time Analysis. However, the intact noradrenergic neurons in CNS may be important to keep normal cardiac autonomic function in SHR Izm for long-Term Analysis.
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Short and long Term Analysis of heart rate variations in spontaneously hypertensive rats: effects of DSP-4 administration.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2005Co-Authors: H. Kawamura, H. Mitsubayashi, T. Miao, T. ShimizuAbstract:The purpose of this study was to investigate whether or not central noradrenergic neurons were involved in the time structure of circadian variation of heart rate (HR) in hypertension. We used spontaneously hypertensive rats (SHR(Izm)) and normotensive controls (Wistar Kyoto rats, WKY(Izm)). We selectively destroyed the noradrenergic neurons in the central nervous system (CNS) by administering noradrenergic neurotoxin, N-(2-chloroethy)-N-ethyl-2-bromobenzylamine (DSP4). Frequency domain measures of variation of HR (VHR) were obtained using the maximum entropy method. The 24-h time frame in VHR is usually dominant in both SHR(Izm) and WKY(Izm). Fourteen days after the administering of DSP4, the mean 24-h systolic arterial pressure (SAP) remained higher in SHR(Izm) than in WKY(Izm). After chemical lesion, ultradian rhythms (12-, 8-, 6-, and 4-h periods) in VHR became more remarkable in both SHR(Izm) and WKY(Izm) than before chemical lesion. Before chemical lesion, an inverse relationship existed between frequency and power spectral density in VHR, demonstrating 1/f(beta) characteristics. The slope of 1/f(beta) in VHR did not differ between SHR(Izm) and WKY(Izm). After the chemical lesion it did not also differ from that of each strain in control period (before lesion). Therefore, the noradrenergic neurons may not affect the time structure of HR in SHR(Izm) and WKY(Izm) for short-Term time Analysis. However, the intact noradrenergic neurons in CNS may be important to keep normal cardiac autonomic function in SHR(Izm) for long-Term Analysis.
Carmen Sánchez - One of the best experts on this subject based on the ideXlab platform.
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Research involving women and health in the Medline database, 1965–2005: co-Term Analysis and visualization of main lines of research
Scientometrics, 2011Co-Authors: M. Angeles Zulueta, Gisela Cantos-mateos, Benjamín Vargas-quesada, Carmen SánchezAbstract:This paper shows the main lines of research concerning health and women, as registered in the Medline database, broken down into four 10-year periods: 1965–1974, 1975–1984, 1985–1994, and 1995–2005. The units of Analysis used were the Medline “MeSH” major Terms, processed by means of co-Term Analysis. For graphic representation, the social network approach was used, with pruning performed by Pathfinder Networks (PFNET), so as to concentrate the displays. Factor Analysis was used to group the descriptors and identify the main lines of research involving health and women. The results show that research on Health and Women has increased and undergone significant changes over the past 40 years, yet such studies are not given due importance.
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Research involving women and health in the Medline database, 1965---2005: co-Term Analysis and visualization of main lines of research
Scientometrics, 2011Co-Authors: M. Angeles Zulueta, Gisela Cantos-mateos, Benjamín Vargas-quesada, Carmen SánchezAbstract:This paper shows the main lines of research concerning health and women, as registered in the Medline database, broken down into four 10-year periods: 1965---1974, 1975---1984, 1985---1994, and 1995---2005. The units of Analysis used were the Medline "MeSH" major Terms, processed by means of co-Term Analysis. For graphic representation, the social network approach was used, with pruning performed by Pathfinder Networks (PFNET), so as to concentrate the displays. Factor Analysis was used to group the descriptors and identify the main lines of research involving health and women. The results show that research on Health and Women has increased and undergone significant changes over the past 40 years, yet such studies are not given due importance.
Mehmet Keskin - One of the best experts on this subject based on the ideXlab platform.
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The use of short-Term Analysis of heart rate variability to assess autonomic function in obese children and its relationship with metabolic syndrome.
Cardiology journal, 2012Co-Authors: Mehmet Erkan Altuncu, Osman Baspinar, Mehmet KeskinAbstract:Background: The cardiovascular autonomic nervous system in obese children is one of the main initiators of coronary heart disease and hypertension and may have a close relationship with insulin resistance. Heart rate variability is one non-invasive method to assess the cardiovascular autonomic system. In this method, low frequency parameters reflect sympathovagal activity, high frequency parameters reflect vagal activity and the ratio of these parameters reflects sympathovagal balance. Methods: In this study, a short-Term Analysis of heart rate variability was conducted in 66 obese children and 40 healthy controls. Results: While high frequency parameter values are lower in the obese group compared to the controls (16.02 ± 12.9 nu vs. 21.45 ± 13.6 nu, p = 0.046), the low frequency/high frequency ratio is found significantly higher (3.79 ± 2.34 vs. 2.25 ± 0.93, p Conclusions: We found that vagal activity was decreased in the obese group and the autonomic nervous system balance was impaired in favor of sympathetic activity in the short-Term heart rate Analysis. (Cardiol J 2012; 19, 5: 501-506)
T. Miao - One of the best experts on this subject based on the ideXlab platform.
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Short and long Term Analysis of heart rate variations in spontaneously hypertensive rats: effects of DSP-4 administration.
Biomedicine & Pharmacotherapy, 2005Co-Authors: H. Kawamura, H. Mitsubayashi, T. Miao, T. ShimizuAbstract:The purpose of this study was to investigate whether or not central noradrenergic neurons were involved in the time structure of circadian variation of heart rate (HR) in hypertension. We used spontaneously hypertensive rats (SHR Izm ) and normotensive controls (Wistar Kyoto rats, WKY Izm ). We selectively destroyed the noradrenergic neurons in the central nervous system (CNS) by administering noradrenergic neurotoxin, N-(2-chloroethy)-N-ethyl-2-bromobenzylamine (DSP4). Frequency domain measures of variation of HR (VHR) were obtained using the maximum entropy method. The 24-h time frame in VHR is usually dominant in both SHR Izm and WKY Izm . Fourteen days after the administering of DSP4, the mean 24-h systolic arterial pressure (SAP) remained higher in SHR Izm than in WKY Izm . After chemical lesion, ultradian rhythms (12-, 8-, 6-, and 4-h periods) in VHR became more remarkable in both SHR Izm and WKY Izm than before chemical lesion. Before chemical lesion, an inverse relationship existed between frequency and power spectral density in VHR, demonstrating 1/fβ characteristics. The slope of 1/f β in VHR did not differ between SHR Izm and WKY Izm . After the chemical lesion it did not also differ from that of each strain in control period (before lesion). Therefore, the noradrenergic neurons may not affect the time structure of HR in SHR Izm and WKY Izm for short-Term time Analysis. However, the intact noradrenergic neurons in CNS may be important to keep normal cardiac autonomic function in SHR Izm for long-Term Analysis.
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Short and long Term Analysis of heart rate variations in spontaneously hypertensive rats: effects of DSP-4 administration.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2005Co-Authors: H. Kawamura, H. Mitsubayashi, T. Miao, T. ShimizuAbstract:The purpose of this study was to investigate whether or not central noradrenergic neurons were involved in the time structure of circadian variation of heart rate (HR) in hypertension. We used spontaneously hypertensive rats (SHR(Izm)) and normotensive controls (Wistar Kyoto rats, WKY(Izm)). We selectively destroyed the noradrenergic neurons in the central nervous system (CNS) by administering noradrenergic neurotoxin, N-(2-chloroethy)-N-ethyl-2-bromobenzylamine (DSP4). Frequency domain measures of variation of HR (VHR) were obtained using the maximum entropy method. The 24-h time frame in VHR is usually dominant in both SHR(Izm) and WKY(Izm). Fourteen days after the administering of DSP4, the mean 24-h systolic arterial pressure (SAP) remained higher in SHR(Izm) than in WKY(Izm). After chemical lesion, ultradian rhythms (12-, 8-, 6-, and 4-h periods) in VHR became more remarkable in both SHR(Izm) and WKY(Izm) than before chemical lesion. Before chemical lesion, an inverse relationship existed between frequency and power spectral density in VHR, demonstrating 1/f(beta) characteristics. The slope of 1/f(beta) in VHR did not differ between SHR(Izm) and WKY(Izm). After the chemical lesion it did not also differ from that of each strain in control period (before lesion). Therefore, the noradrenergic neurons may not affect the time structure of HR in SHR(Izm) and WKY(Izm) for short-Term time Analysis. However, the intact noradrenergic neurons in CNS may be important to keep normal cardiac autonomic function in SHR(Izm) for long-Term Analysis.
