The Experts below are selected from a list of 1485 Experts worldwide ranked by ideXlab platform

Zhonghua Ling - One of the best experts on this subject based on the ideXlab platform.

  • covalently antibacterial alginate chitosan hydrogel dressing integrated gelatin microspheres containing Tetracycline Hydrochloride for wound healing
    Materials Science and Engineering: C, 2017
    Co-Authors: Huinan Chen, Xiaodong Xing, Tianle Zhou, Yong Chen, Zhonghua Ling, Xiaohong Hu
    Abstract:

    Abstract An antibacterial and biodegradable composite hydrogel dressing integrated with microspheres is developed for drug delivery and wound healing. The mechanism of gelation is attributed to the Schiff-base reaction between aldehyde and amino groups of oxidized alginate (OAlg) and carboxymethyl chitosan (CMCS). To enhance antibacterial and mechanical properties, Tetracycline Hydrochloride (TH) loaded gelatin microspheres (GMs) were fabricated by an emulsion cross-linking method, followed by integrating into the OAlg-CMCS hydrogel to produce a composite gel dressing. In vitro gelation time, swelling, degradation, compressive modulus and rheological properties of the gel dressing were investigated as the function of microsphere ratios. With increasing ratios of microspheres from 10 to 40 mg/mL, the composite dressing manifested shorter gelation time and lower swelling ratios, as well as higher mechanical strength. Comparing to other formulations, the gel dressing with 30 mg/mL microspheres showed more suitable stabilities and mechanical properties for wound healing. Also, in vitro drug release results showed that the loaded TH could be sustained release from the composite gel dressing by contrast with pure hydrogels and microspheres. Furthermore, powerful bacteria growth inhibition effects against Escherichia coli and Staphylococcus aureus suggested that the composite gel dressing, especially the one with 30 mg/mL GMs containing TH, has a promising future in treatment of bacterial infection.

  • Covalently antibacterial alginate-chitosan hydrogel dressing integrated gelatin microspheres containing Tetracycline Hydrochloride for wound healing.
    Materials science & engineering. C Materials for biological applications, 2016
    Co-Authors: Huinan Chen, Xiaodong Xing, Tianle Zhou, Yong Chen, Huaping Tan, Yang Jia, Zhonghua Ling
    Abstract:

    Abstract An antibacterial and biodegradable composite hydrogel dressing integrated with microspheres is developed for drug delivery and wound healing. The mechanism of gelation is attributed to the Schiff-base reaction between aldehyde and amino groups of oxidized alginate (OAlg) and carboxymethyl chitosan (CMCS). To enhance antibacterial and mechanical properties, Tetracycline Hydrochloride (TH) loaded gelatin microspheres (GMs) were fabricated by an emulsion cross-linking method, followed by integrating into the OAlg-CMCS hydrogel to produce a composite gel dressing. In vitro gelation time, swelling, degradation, compressive modulus and rheological properties of the gel dressing were investigated as the function of microsphere ratios. With increasing ratios of microspheres from 10 to 40 mg/mL, the composite dressing manifested shorter gelation time and lower swelling ratios, as well as higher mechanical strength. Comparing to other formulations, the gel dressing with 30 mg/mL microspheres showed more suitable stabilities and mechanical properties for wound healing. Also, in vitro drug release results showed that the loaded TH could be sustained release from the composite gel dressing by contrast with pure hydrogels and microspheres. Furthermore, powerful bacteria growth inhibition effects against Escherichia coli and Staphylococcus aureus suggested that the composite gel dressing, especially the one with 30 mg/mL GMs containing TH, has a promising future in treatment of bacterial infection.

Huinan Chen - One of the best experts on this subject based on the ideXlab platform.

  • covalently antibacterial alginate chitosan hydrogel dressing integrated gelatin microspheres containing Tetracycline Hydrochloride for wound healing
    Materials Science and Engineering: C, 2017
    Co-Authors: Huinan Chen, Xiaodong Xing, Tianle Zhou, Yong Chen, Zhonghua Ling, Xiaohong Hu
    Abstract:

    Abstract An antibacterial and biodegradable composite hydrogel dressing integrated with microspheres is developed for drug delivery and wound healing. The mechanism of gelation is attributed to the Schiff-base reaction between aldehyde and amino groups of oxidized alginate (OAlg) and carboxymethyl chitosan (CMCS). To enhance antibacterial and mechanical properties, Tetracycline Hydrochloride (TH) loaded gelatin microspheres (GMs) were fabricated by an emulsion cross-linking method, followed by integrating into the OAlg-CMCS hydrogel to produce a composite gel dressing. In vitro gelation time, swelling, degradation, compressive modulus and rheological properties of the gel dressing were investigated as the function of microsphere ratios. With increasing ratios of microspheres from 10 to 40 mg/mL, the composite dressing manifested shorter gelation time and lower swelling ratios, as well as higher mechanical strength. Comparing to other formulations, the gel dressing with 30 mg/mL microspheres showed more suitable stabilities and mechanical properties for wound healing. Also, in vitro drug release results showed that the loaded TH could be sustained release from the composite gel dressing by contrast with pure hydrogels and microspheres. Furthermore, powerful bacteria growth inhibition effects against Escherichia coli and Staphylococcus aureus suggested that the composite gel dressing, especially the one with 30 mg/mL GMs containing TH, has a promising future in treatment of bacterial infection.

  • Covalently antibacterial alginate-chitosan hydrogel dressing integrated gelatin microspheres containing Tetracycline Hydrochloride for wound healing.
    Materials science & engineering. C Materials for biological applications, 2016
    Co-Authors: Huinan Chen, Xiaodong Xing, Tianle Zhou, Yong Chen, Huaping Tan, Yang Jia, Zhonghua Ling
    Abstract:

    Abstract An antibacterial and biodegradable composite hydrogel dressing integrated with microspheres is developed for drug delivery and wound healing. The mechanism of gelation is attributed to the Schiff-base reaction between aldehyde and amino groups of oxidized alginate (OAlg) and carboxymethyl chitosan (CMCS). To enhance antibacterial and mechanical properties, Tetracycline Hydrochloride (TH) loaded gelatin microspheres (GMs) were fabricated by an emulsion cross-linking method, followed by integrating into the OAlg-CMCS hydrogel to produce a composite gel dressing. In vitro gelation time, swelling, degradation, compressive modulus and rheological properties of the gel dressing were investigated as the function of microsphere ratios. With increasing ratios of microspheres from 10 to 40 mg/mL, the composite dressing manifested shorter gelation time and lower swelling ratios, as well as higher mechanical strength. Comparing to other formulations, the gel dressing with 30 mg/mL microspheres showed more suitable stabilities and mechanical properties for wound healing. Also, in vitro drug release results showed that the loaded TH could be sustained release from the composite gel dressing by contrast with pure hydrogels and microspheres. Furthermore, powerful bacteria growth inhibition effects against Escherichia coli and Staphylococcus aureus suggested that the composite gel dressing, especially the one with 30 mg/mL GMs containing TH, has a promising future in treatment of bacterial infection.

Xin Xiao - One of the best experts on this subject based on the ideXlab platform.

  • efficient adsorption and visible light photocatalytic degradation of Tetracycline Hydrochloride using mesoporous bioi microspheres
    Journal of Hazardous Materials, 2012
    Co-Authors: Rong Hao, Xin Xiao, Xiaoxi Zuo, Junmin Nan, Weide Zhang
    Abstract:

    A novel microsphere-like BiOI hierarchical material was successfully synthesized by a one-step solution method at room temperature using polyvinylpyrrolidone (PVP) as structure directing reagent, its morphology, structure, surface area, photoabsorption were characterized, and the removal of Tetracycline Hydrochloride (TC) was evaluated under dark adsorption and visible light irradiation. It was shown that the BiOI microspheres formed in the precursor solution with PVP exhibit a mesoporous surface layer, 28.1m(2)g(-1) surface area, 1.91 eV band gap energy (E(g) value), and twofold removal ability to Tetracycline Hydrochloride (TC), i.e. adsorptive separation and visible light photocatalytic degradation. The adsorption process of TC on BiOI microspheres can be described by pseudo-second-order kinetics model and both Freundlich and Langmuir equations well described the adsorption isotherm but the former is better. More importantly, the BiOI microspheres exhibit an excellent photocatalytic degradation and mineralization capability to TC under visible light irradiation, which comes from its electronic band structure, high surface area and high surface-to-volume ratio. In addition, the BiOI microspheres are stable during the reaction and can be used repeatedly, showing promising prospect for the treatment of TCs in future industrial application.

  • efficient adsorption and visible light photocatalytic degradation of Tetracycline Hydrochloride using mesoporous bioi microspheres
    Journal of Hazardous Materials, 2012
    Co-Authors: Xin Xiao, Weide Zhang
    Abstract:

    Abstract A novel microsphere-like BiOI hierarchical material was successfully synthesized by a one-step solution method at room temperature using polyvinylpyrrolidone (PVP) as structure directing reagent, its morphology, structure, surface area, photoabsorption were characterized, and the removal of Tetracycline Hydrochloride (TC) was evaluated under dark adsorption and visible light irradiation. It was shown that the BiOI microspheres formed in the precursor solution with PVP exhibit a mesoporous surface layer, 28.1 m2 g−1 surface area, 1.91 eV band gap energy (Eg value), and twofold removal ability to Tetracycline Hydrochloride (TC), i.e. adsorptive separation and visible light photocatalytic degradation. The adsorption process of TC on BiOI microspheres can be described by pseudo-second-order kinetics model and both Freundlich and Langmuir equations well described the adsorption isotherm but the former is better. More importantly, the BiOI microspheres exhibit an excellent photocatalytic degradation and mineralization capability to TC under visible light irradiation, which comes from its electronic band structure, high surface area and high surface-to-volume ratio. In addition, the BiOI microspheres are stable during the reaction and can be used repeatedly, showing promising prospect for the treatment of TCs in future industrial application.

Xiaohong Hu - One of the best experts on this subject based on the ideXlab platform.

  • covalently antibacterial alginate chitosan hydrogel dressing integrated gelatin microspheres containing Tetracycline Hydrochloride for wound healing
    Materials Science and Engineering: C, 2017
    Co-Authors: Huinan Chen, Xiaodong Xing, Tianle Zhou, Yong Chen, Zhonghua Ling, Xiaohong Hu
    Abstract:

    Abstract An antibacterial and biodegradable composite hydrogel dressing integrated with microspheres is developed for drug delivery and wound healing. The mechanism of gelation is attributed to the Schiff-base reaction between aldehyde and amino groups of oxidized alginate (OAlg) and carboxymethyl chitosan (CMCS). To enhance antibacterial and mechanical properties, Tetracycline Hydrochloride (TH) loaded gelatin microspheres (GMs) were fabricated by an emulsion cross-linking method, followed by integrating into the OAlg-CMCS hydrogel to produce a composite gel dressing. In vitro gelation time, swelling, degradation, compressive modulus and rheological properties of the gel dressing were investigated as the function of microsphere ratios. With increasing ratios of microspheres from 10 to 40 mg/mL, the composite dressing manifested shorter gelation time and lower swelling ratios, as well as higher mechanical strength. Comparing to other formulations, the gel dressing with 30 mg/mL microspheres showed more suitable stabilities and mechanical properties for wound healing. Also, in vitro drug release results showed that the loaded TH could be sustained release from the composite gel dressing by contrast with pure hydrogels and microspheres. Furthermore, powerful bacteria growth inhibition effects against Escherichia coli and Staphylococcus aureus suggested that the composite gel dressing, especially the one with 30 mg/mL GMs containing TH, has a promising future in treatment of bacterial infection.

Weide Zhang - One of the best experts on this subject based on the ideXlab platform.

  • efficient adsorption and visible light photocatalytic degradation of Tetracycline Hydrochloride using mesoporous bioi microspheres
    Journal of Hazardous Materials, 2012
    Co-Authors: Rong Hao, Xin Xiao, Xiaoxi Zuo, Junmin Nan, Weide Zhang
    Abstract:

    A novel microsphere-like BiOI hierarchical material was successfully synthesized by a one-step solution method at room temperature using polyvinylpyrrolidone (PVP) as structure directing reagent, its morphology, structure, surface area, photoabsorption were characterized, and the removal of Tetracycline Hydrochloride (TC) was evaluated under dark adsorption and visible light irradiation. It was shown that the BiOI microspheres formed in the precursor solution with PVP exhibit a mesoporous surface layer, 28.1m(2)g(-1) surface area, 1.91 eV band gap energy (E(g) value), and twofold removal ability to Tetracycline Hydrochloride (TC), i.e. adsorptive separation and visible light photocatalytic degradation. The adsorption process of TC on BiOI microspheres can be described by pseudo-second-order kinetics model and both Freundlich and Langmuir equations well described the adsorption isotherm but the former is better. More importantly, the BiOI microspheres exhibit an excellent photocatalytic degradation and mineralization capability to TC under visible light irradiation, which comes from its electronic band structure, high surface area and high surface-to-volume ratio. In addition, the BiOI microspheres are stable during the reaction and can be used repeatedly, showing promising prospect for the treatment of TCs in future industrial application.

  • efficient adsorption and visible light photocatalytic degradation of Tetracycline Hydrochloride using mesoporous bioi microspheres
    Journal of Hazardous Materials, 2012
    Co-Authors: Xin Xiao, Weide Zhang
    Abstract:

    Abstract A novel microsphere-like BiOI hierarchical material was successfully synthesized by a one-step solution method at room temperature using polyvinylpyrrolidone (PVP) as structure directing reagent, its morphology, structure, surface area, photoabsorption were characterized, and the removal of Tetracycline Hydrochloride (TC) was evaluated under dark adsorption and visible light irradiation. It was shown that the BiOI microspheres formed in the precursor solution with PVP exhibit a mesoporous surface layer, 28.1 m2 g−1 surface area, 1.91 eV band gap energy (Eg value), and twofold removal ability to Tetracycline Hydrochloride (TC), i.e. adsorptive separation and visible light photocatalytic degradation. The adsorption process of TC on BiOI microspheres can be described by pseudo-second-order kinetics model and both Freundlich and Langmuir equations well described the adsorption isotherm but the former is better. More importantly, the BiOI microspheres exhibit an excellent photocatalytic degradation and mineralization capability to TC under visible light irradiation, which comes from its electronic band structure, high surface area and high surface-to-volume ratio. In addition, the BiOI microspheres are stable during the reaction and can be used repeatedly, showing promising prospect for the treatment of TCs in future industrial application.