The Experts below are selected from a list of 10419 Experts worldwide ranked by ideXlab platform
Jerry R. Nelson - One of the best experts on this subject based on the ideXlab platform.
-
Permeability of latex and Thermoplastic Elastomer gloves to the bacteriophage φX174
American Journal of Infection Control, 1993Co-Authors: Curtis P. Hamann, Jerry R. NelsonAbstract:BACKGROUND: Most studies challenging the integrity of the glove barrier have compared the permeability of vinyl and latex gloves. However, no studies of a new nonlatex, nonvinyl Thermoplastic Elastomer have been reported. This pilot study therefore compared the protective barriers provided by latex and Thermoplastic Elastomer surgical gloves against penetration of the bacteriophage phi X174. METHODS: Twenty Thermoplastic Elastomer gloves and 25 commercially available latex gloves (20 brand 1, 5 brand 2) were filled with a sterile serum surrogate and exposed to the phi X174 virus in a flask, with shaking for 180 minutes at 37 degrees C. Aliquots of 5 ml were withdrawn at baseline, 30, 60, 120, and 180 minutes and assayed by a standard plaque assay. The remaining contents of the gloves were then tested by an extremely sensitive qualitative assay (plaque assay without dilution of the sample). RESULTS: With the standard plaque assay, virus was detected in 30% of the brand 1 latex gloves, in 80% of the brand 2 latex gloves, but in none of the Thermoplastic Elastomer gloves. The qualitative assay, which can detect even a single virus in the entire glove contents, had positive results for 30% of the Thermoplastic Elastomer gloves, 70% of the brand 1 gloves, and 100% of the brand 2 gloves. CONCLUSIONS: Despite the small sample, the results of this stringent assay suggest that the mechanical barrier offered by Thermoplastic Elastomer gloves is equal to or better than that provided by the latex gloves tested. Clinical studies are needed to evaluate Thermoplastic Elastomer gloves, which may withstand mechanical stress better than latex or vinyl. Thermoplastic Elastomer gloves may therefore be a desirable alternative for health care workers in high-risk settings or for individuals with latex allergies.
-
Permeability of latex and Thermoplastic Elastomer gloves to the bacteriophage φX174
AJIC: American Journal of Infection Control, 1993Co-Authors: Curtis P. Hamann, Jerry R. NelsonAbstract:Background: Most studies challenging the integrity of the glove barrier have compared the permeability of vinyl and latex gloves. However, no studies of a new nonlatex, nonvinyl Thermoplastic Elastomer have been reported. This pilot study therefore compared the protective barriers provided by latex and Thermoplastic Elastomer surgical gloves against penetration of the bacteriophage φX174. Methods: Twenty Thermoplastic Elastomer gloves and 25 commercially available latex gloves (20. brand 1, 5 brand 2) were filled with a sterile serum surrogate and exposed to the φX174 virus in a flask, with shaking for 180 minutes at 37° C. Aliquots of 5 ml were withdrawn at baseline, 30, 60, 120, and 180 minutes and assayed by a standard plaque assay. The remaining contents of the gloves were then tested by an extremely sensitive qualitative assay (plaque assay without dilution of the sample). Results: With the standard plaque assay, virus was detected in 30% of the brand 1 latex gloves, in 80% of the brand 2 latex gloves, but in none of the Thermoplastic Elastomer gloves. The qualitative assay, which can detect even a single virus in the entire glove contents, had positive results for 30% of the Thermoplastic Elastomer gloves, 70% of the brand 1 gloves, and 100% of the brand 2 gloves. Conclusions: Despite the small sample, the results of this stringent assay suggest that the mechanical barrier offered by Thermoplastic Elastomer gloves is equal to or better than that provided by the latex gloves tested. Clinical studies are needed to evaluate Thermoplastic Elastomer gloves, which may withstand mechanical stress better than latex or vinyl. Thermoplastic Elastomer gloves may therefore be a desirable alternative for health care workers in high-risk settings or for individuals with latex allergies. © 1993.
Krystal Lovejoy - One of the best experts on this subject based on the ideXlab platform.
-
A nanostructured carbon-reinforced polyisobutylene-based Thermoplastic Elastomer
Biomaterials, 2010Co-Authors: Judit E. Puskas, Elizabeth A. Foreman-orlowski, Sara E. Porosky, Michelle M. Evancho-chapman, Mirosława El Fray, Marta Piatek, Goy Teck Lim, Piotr Prowans, Steven P Schmidt, Krystal LovejoyAbstract:This paper presents the synthesis and characterization of a polyisobutylene (PIB)-based nanostructured carbon-reinforced Thermoplastic Elastomer. This Thermoplastic Elastomer is based on a self-assembling block copolymer having a branched PIB core carrying -OH functional groups at each branch point, flanked by blocks of poly(isobutylene-co-para-methylstyrene). The block copolymer has thermolabile physical crosslinks and can be processed as a plastic, yet retains its rubbery properties at room temperature. The carbon-reinforced Thermoplastic Elastomer had more than twice the tensile strength of the neat polymer, exceeding the strength of medical grade silicone rubber, while remaining significantly softer. The carbon-reinforced Thermoplastic Elastomer displayed a high Tg of 126 °C, rendering the material steam-sterilizable. The carbon also acted as a free radical trap, increasing the onset temperature of thermal decomposition in the neat polymer from 256.6 °C to 327.7 °C. The carbon-reinforced Thermoplastic Elastomer had the lowest water contact angle at 82° and surface nano-topography. After 180 days of implantation into rabbit soft tissues, the carbon-reinforced Thermoplastic Elastomer had the thinnest tissue capsule around the microdumbbell specimens, with no eosinophiles present. The material also showed excellent integration into bones. © 2009 Elsevier Ltd. All rights reserved.
-
A nanostructured carbon-reinforced polyisobutylene-based Thermoplastic Elastomer.
Biomaterials, 2009Co-Authors: Judit E. Puskas, Elizabeth A. Foreman-orlowski, Sara E. Porosky, Michelle M. Evancho-chapman, Mirosława El Fray, Piotr Prowans, Steven P Schmidt, Marta Piątek, Krystal LovejoyAbstract:Abstract This paper presents the synthesis and characterization of a polyisobutylene (PIB)-based nanostructured carbon-reinforced Thermoplastic Elastomer. This Thermoplastic Elastomer is based on a self-assembling block copolymer having a branched PIB core carrying –OH functional groups at each branch point, flanked by blocks of poly(isobutylene-co-para-methylstyrene). The block copolymer has thermolabile physical crosslinks and can be processed as a plastic, yet retains its rubbery properties at room temperature. The carbon-reinforced Thermoplastic Elastomer had more than twice the tensile strength of the neat polymer, exceeding the strength of medical grade silicone rubber, while remaining significantly softer. The carbon-reinforced Thermoplastic Elastomer displayed a high Tg of 126 °C, rendering the material steam-sterilizable. The carbon also acted as a free radical trap, increasing the onset temperature of thermal decomposition in the neat polymer from 256.6 °C to 327.7 °C. The carbon-reinforced Thermoplastic Elastomer had the lowest water contact angle at 82° and surface nano-topography. After 180 days of implantation into rabbit soft tissues, the carbon-reinforced Thermoplastic Elastomer had the thinnest tissue capsule around the microdumbbell specimens, with no eosinophiles present. The material also showed excellent integration into bones.
Curtis P. Hamann - One of the best experts on this subject based on the ideXlab platform.
-
Permeability of latex and Thermoplastic Elastomer gloves to the bacteriophage φX174
American Journal of Infection Control, 1993Co-Authors: Curtis P. Hamann, Jerry R. NelsonAbstract:BACKGROUND: Most studies challenging the integrity of the glove barrier have compared the permeability of vinyl and latex gloves. However, no studies of a new nonlatex, nonvinyl Thermoplastic Elastomer have been reported. This pilot study therefore compared the protective barriers provided by latex and Thermoplastic Elastomer surgical gloves against penetration of the bacteriophage phi X174. METHODS: Twenty Thermoplastic Elastomer gloves and 25 commercially available latex gloves (20 brand 1, 5 brand 2) were filled with a sterile serum surrogate and exposed to the phi X174 virus in a flask, with shaking for 180 minutes at 37 degrees C. Aliquots of 5 ml were withdrawn at baseline, 30, 60, 120, and 180 minutes and assayed by a standard plaque assay. The remaining contents of the gloves were then tested by an extremely sensitive qualitative assay (plaque assay without dilution of the sample). RESULTS: With the standard plaque assay, virus was detected in 30% of the brand 1 latex gloves, in 80% of the brand 2 latex gloves, but in none of the Thermoplastic Elastomer gloves. The qualitative assay, which can detect even a single virus in the entire glove contents, had positive results for 30% of the Thermoplastic Elastomer gloves, 70% of the brand 1 gloves, and 100% of the brand 2 gloves. CONCLUSIONS: Despite the small sample, the results of this stringent assay suggest that the mechanical barrier offered by Thermoplastic Elastomer gloves is equal to or better than that provided by the latex gloves tested. Clinical studies are needed to evaluate Thermoplastic Elastomer gloves, which may withstand mechanical stress better than latex or vinyl. Thermoplastic Elastomer gloves may therefore be a desirable alternative for health care workers in high-risk settings or for individuals with latex allergies.
-
Permeability of latex and Thermoplastic Elastomer gloves to the bacteriophage φX174
AJIC: American Journal of Infection Control, 1993Co-Authors: Curtis P. Hamann, Jerry R. NelsonAbstract:Background: Most studies challenging the integrity of the glove barrier have compared the permeability of vinyl and latex gloves. However, no studies of a new nonlatex, nonvinyl Thermoplastic Elastomer have been reported. This pilot study therefore compared the protective barriers provided by latex and Thermoplastic Elastomer surgical gloves against penetration of the bacteriophage φX174. Methods: Twenty Thermoplastic Elastomer gloves and 25 commercially available latex gloves (20. brand 1, 5 brand 2) were filled with a sterile serum surrogate and exposed to the φX174 virus in a flask, with shaking for 180 minutes at 37° C. Aliquots of 5 ml were withdrawn at baseline, 30, 60, 120, and 180 minutes and assayed by a standard plaque assay. The remaining contents of the gloves were then tested by an extremely sensitive qualitative assay (plaque assay without dilution of the sample). Results: With the standard plaque assay, virus was detected in 30% of the brand 1 latex gloves, in 80% of the brand 2 latex gloves, but in none of the Thermoplastic Elastomer gloves. The qualitative assay, which can detect even a single virus in the entire glove contents, had positive results for 30% of the Thermoplastic Elastomer gloves, 70% of the brand 1 gloves, and 100% of the brand 2 gloves. Conclusions: Despite the small sample, the results of this stringent assay suggest that the mechanical barrier offered by Thermoplastic Elastomer gloves is equal to or better than that provided by the latex gloves tested. Clinical studies are needed to evaluate Thermoplastic Elastomer gloves, which may withstand mechanical stress better than latex or vinyl. Thermoplastic Elastomer gloves may therefore be a desirable alternative for health care workers in high-risk settings or for individuals with latex allergies. © 1993.
Judit E. Puskas - One of the best experts on this subject based on the ideXlab platform.
-
A nanostructured carbon-reinforced polyisobutylene-based Thermoplastic Elastomer
Biomaterials, 2010Co-Authors: Judit E. Puskas, Elizabeth A. Foreman-orlowski, Sara E. Porosky, Michelle M. Evancho-chapman, Mirosława El Fray, Marta Piatek, Goy Teck Lim, Piotr Prowans, Steven P Schmidt, Krystal LovejoyAbstract:This paper presents the synthesis and characterization of a polyisobutylene (PIB)-based nanostructured carbon-reinforced Thermoplastic Elastomer. This Thermoplastic Elastomer is based on a self-assembling block copolymer having a branched PIB core carrying -OH functional groups at each branch point, flanked by blocks of poly(isobutylene-co-para-methylstyrene). The block copolymer has thermolabile physical crosslinks and can be processed as a plastic, yet retains its rubbery properties at room temperature. The carbon-reinforced Thermoplastic Elastomer had more than twice the tensile strength of the neat polymer, exceeding the strength of medical grade silicone rubber, while remaining significantly softer. The carbon-reinforced Thermoplastic Elastomer displayed a high Tg of 126 °C, rendering the material steam-sterilizable. The carbon also acted as a free radical trap, increasing the onset temperature of thermal decomposition in the neat polymer from 256.6 °C to 327.7 °C. The carbon-reinforced Thermoplastic Elastomer had the lowest water contact angle at 82° and surface nano-topography. After 180 days of implantation into rabbit soft tissues, the carbon-reinforced Thermoplastic Elastomer had the thinnest tissue capsule around the microdumbbell specimens, with no eosinophiles present. The material also showed excellent integration into bones. © 2009 Elsevier Ltd. All rights reserved.
-
A nanostructured carbon-reinforced polyisobutylene-based Thermoplastic Elastomer.
Biomaterials, 2009Co-Authors: Judit E. Puskas, Elizabeth A. Foreman-orlowski, Sara E. Porosky, Michelle M. Evancho-chapman, Mirosława El Fray, Piotr Prowans, Steven P Schmidt, Marta Piątek, Krystal LovejoyAbstract:Abstract This paper presents the synthesis and characterization of a polyisobutylene (PIB)-based nanostructured carbon-reinforced Thermoplastic Elastomer. This Thermoplastic Elastomer is based on a self-assembling block copolymer having a branched PIB core carrying –OH functional groups at each branch point, flanked by blocks of poly(isobutylene-co-para-methylstyrene). The block copolymer has thermolabile physical crosslinks and can be processed as a plastic, yet retains its rubbery properties at room temperature. The carbon-reinforced Thermoplastic Elastomer had more than twice the tensile strength of the neat polymer, exceeding the strength of medical grade silicone rubber, while remaining significantly softer. The carbon-reinforced Thermoplastic Elastomer displayed a high Tg of 126 °C, rendering the material steam-sterilizable. The carbon also acted as a free radical trap, increasing the onset temperature of thermal decomposition in the neat polymer from 256.6 °C to 327.7 °C. The carbon-reinforced Thermoplastic Elastomer had the lowest water contact angle at 82° and surface nano-topography. After 180 days of implantation into rabbit soft tissues, the carbon-reinforced Thermoplastic Elastomer had the thinnest tissue capsule around the microdumbbell specimens, with no eosinophiles present. The material also showed excellent integration into bones.
Gilles Lubineau - One of the best experts on this subject based on the ideXlab platform.
-
Coaxial Thermoplastic Elastomer-Wrapped Carbon Nanotube Fibers for Deformable and Wearable Strain Sensors
Advanced Functional Materials, 2018Co-Authors: Jian Zhou, Xuezhu Xu, Yangyang Xin, Gilles LubineauAbstract:Highly conductive and stretchable fibers are crucial components of wearable electronics systems. Excellent electrical conductivity, stretchability, and wearability are required from such fibers. Existing technologies still display limited performances in these design requirements. Here, achieving highly stretchable and sensitive strain sensors by using a coaxial structure, prepared via coaxial wet spinning of Thermoplastic Elastomer-wrapped carbon nanotube fibers, is proposed. The sensors attain high sensitivity (with a gauge factor of 425 at 100% strain), high stretchability, and high linearity. They are also reproducible and durable. Their use as safe sensing components on deformable cable, expandable surfaces, and wearable textiles is demonstrated.
