The Experts below are selected from a list of 186 Experts worldwide ranked by ideXlab platform
Rubens Belfort - One of the best experts on this subject based on the ideXlab platform.
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Antihelminthic drugs in diffuse unilateral subacute neuroretinitis.
American journal of ophthalmology, 1998Co-Authors: Antonio Marcelo Barbante Casella, Michel Eid Farah, Rubens BelfortAbstract:To evaluate the efficacy of ivermectin and Thiabendazole in confirmed cases of diffuse unilateral subacute neuroretinitis. Two patients with diffuse unilateral subacute neuroretinitis were treated with anthelminthic drugs. The first patient was treated with ivermectin and the second, with Thiabendazole. The worms were still mobile after treatment with ivermectin or Thiabendazole. With the application of photocoagulation, the organisms were destroyed, and the patients' vision improved. In these two patients, ivermectin and Thiabendazole were not effective in treating confirmed diffuse unilateral subacute neuroretinitis.
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antihelminthic drugs in diffuse unilateral subacute neuroretinitis
American Journal of Ophthalmology, 1998Co-Authors: Antonio Marcelo Barbante Casella, Michel Eid Farah, Rubens BelfortAbstract:Purpose: To evaluate the efficacy of ivermectin and Thiabendazole in confirmed cases of diffuse unilateral subacute neuroretinitis. Method: Two patients with diffuse unilateral subacute neuroretinitis were treated with anthelminthic drugs. The first patient was treated with ivermectin and the second, with Thiabendazole. Results: The worms were still mobile after treatment with ivermectin or Thiabendazole. With the application of photocoagulation, the organisms were destroyed, and the patients' vision improved. Conclusion: In these two patients, ivermectin and Thiabendazole were not effective in treating confirmed diffuse unilateral subacute neuroretinitis.
Antonio Marcelo Barbante Casella - One of the best experts on this subject based on the ideXlab platform.
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Antihelminthic drugs in diffuse unilateral subacute neuroretinitis.
American journal of ophthalmology, 1998Co-Authors: Antonio Marcelo Barbante Casella, Michel Eid Farah, Rubens BelfortAbstract:To evaluate the efficacy of ivermectin and Thiabendazole in confirmed cases of diffuse unilateral subacute neuroretinitis. Two patients with diffuse unilateral subacute neuroretinitis were treated with anthelminthic drugs. The first patient was treated with ivermectin and the second, with Thiabendazole. The worms were still mobile after treatment with ivermectin or Thiabendazole. With the application of photocoagulation, the organisms were destroyed, and the patients' vision improved. In these two patients, ivermectin and Thiabendazole were not effective in treating confirmed diffuse unilateral subacute neuroretinitis.
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antihelminthic drugs in diffuse unilateral subacute neuroretinitis
American Journal of Ophthalmology, 1998Co-Authors: Antonio Marcelo Barbante Casella, Michel Eid Farah, Rubens BelfortAbstract:Purpose: To evaluate the efficacy of ivermectin and Thiabendazole in confirmed cases of diffuse unilateral subacute neuroretinitis. Method: Two patients with diffuse unilateral subacute neuroretinitis were treated with anthelminthic drugs. The first patient was treated with ivermectin and the second, with Thiabendazole. Results: The worms were still mobile after treatment with ivermectin or Thiabendazole. With the application of photocoagulation, the organisms were destroyed, and the patients' vision improved. Conclusion: In these two patients, ivermectin and Thiabendazole were not effective in treating confirmed diffuse unilateral subacute neuroretinitis.
Michel Eid Farah - One of the best experts on this subject based on the ideXlab platform.
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Antihelminthic drugs in diffuse unilateral subacute neuroretinitis.
American journal of ophthalmology, 1998Co-Authors: Antonio Marcelo Barbante Casella, Michel Eid Farah, Rubens BelfortAbstract:To evaluate the efficacy of ivermectin and Thiabendazole in confirmed cases of diffuse unilateral subacute neuroretinitis. Two patients with diffuse unilateral subacute neuroretinitis were treated with anthelminthic drugs. The first patient was treated with ivermectin and the second, with Thiabendazole. The worms were still mobile after treatment with ivermectin or Thiabendazole. With the application of photocoagulation, the organisms were destroyed, and the patients' vision improved. In these two patients, ivermectin and Thiabendazole were not effective in treating confirmed diffuse unilateral subacute neuroretinitis.
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antihelminthic drugs in diffuse unilateral subacute neuroretinitis
American Journal of Ophthalmology, 1998Co-Authors: Antonio Marcelo Barbante Casella, Michel Eid Farah, Rubens BelfortAbstract:Purpose: To evaluate the efficacy of ivermectin and Thiabendazole in confirmed cases of diffuse unilateral subacute neuroretinitis. Method: Two patients with diffuse unilateral subacute neuroretinitis were treated with anthelminthic drugs. The first patient was treated with ivermectin and the second, with Thiabendazole. Results: The worms were still mobile after treatment with ivermectin or Thiabendazole. With the application of photocoagulation, the organisms were destroyed, and the patients' vision improved. Conclusion: In these two patients, ivermectin and Thiabendazole were not effective in treating confirmed diffuse unilateral subacute neuroretinitis.
Massimiliano Delpero - One of the best experts on this subject based on the ideXlab platform.
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in vitro aneugenic effects of the fungicide Thiabendazole evaluated in human lymphocytes by the micronucleus assay
Archives of Toxicology, 2011Co-Authors: Alfredo Santovito, Piero Cervella, Massimiliano DelperoAbstract:Thiabendazole is a benzimidazole-derived compound widely employed in agriculture as anthelmintic and fungicide. It is also used as a post-harvest fungicide for imported citrus fruits during transport and storage, and thus, it was found at high concentration in fruits and vegetables. Several studies have analyzed the potential genotoxic effect of Thiabendazole on different prokaryotic and eukaryotic systems, but in many cases, results were contradictory. In the present study, the genotoxic potential of Thiabendazole have been evaluated, by micronucleus assay in freshly isolated human peripheral lymphocytes. The cells were incubated with 0.5, 5 and 50 μg/ml concentrations of the tested substance for 48 h at 37°C. Mitomycin C at final concentration of 0.01 μg/ml culture was used as a positive control. The results indicated that the Thiabendazole significantly (P < 0.05) increased the micronucleus frequency compared with the negative control in all treatment concentrations, indicating a potential aneugenic hazard of Thiabendazole in cultured human peripheral lymphocytes. The cytokinesis-block proliferation index value, however, was not decreased significantly compared with the negative control. Significant (P < 0.05) differences in the micronuclei frequency were also found between the lower dose (0.5 μg/ml) and the other two analyzed doses of Thiabendazole. In contrast, no differences were found between 5 and 50 μg/ml of Thiabendazole and between DMSO and negative control. Finally, control cultures treated with the known mutagen MMC showed a very consistent increase in MN with respect to the negative controls.
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In vitro aneugenic effects of the fungicide Thiabendazole evaluated in human lymphocytes by the micronucleus assay
Archives of toxicology, 2010Co-Authors: Alfredo Santovito, Piero Cervella, Massimiliano DelperoAbstract:Thiabendazole is a benzimidazole-derived compound widely employed in agriculture as anthelmintic and fungicide. It is also used as a post-harvest fungicide for imported citrus fruits during transport and storage, and thus, it was found at high concentration in fruits and vegetables. Several studies have analyzed the potential genotoxic effect of Thiabendazole on different prokaryotic and eukaryotic systems, but in many cases, results were contradictory. In the present study, the genotoxic potential of Thiabendazole have been evaluated, by micronucleus assay in freshly isolated human peripheral lymphocytes. The cells were incubated with 0.5, 5 and 50 μg/ml concentrations of the tested substance for 48 h at 37°C. Mitomycin C at final concentration of 0.01 μg/ml culture was used as a positive control. The results indicated that the Thiabendazole significantly (P
Luca Rastrelli - One of the best experts on this subject based on the ideXlab platform.
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determination of carbendazim Thiabendazole and thiophanate methyl in banana musa acuminata samples imported to italy
Food Chemistry, 2004Co-Authors: Attilio Veneziano, Swizly Arana, Francesco De Simone, Giovanni Vacca, Luca RastrelliAbstract:Abstract The occurrence of benzimidazole fungicides (benomyl and its metabolites carbendazim, Thiabendazole and thiophanate-methyl) in 50 banana samples imported to Italy from Ecuador, Panama and Costa Rica during 2002–2003 was investigated. In 11 samples, Thiabendazole was found at concentrations ranging from 0.050 to 2.510 mg/kg. In five samples, carbendazim was found at concentrations ranging from 0.140 to 1.100 mg/kg, whereas thiophanate-methyl was not detected in any sample. Analysis was carried out using HPLC-DAD and positive samples were confirmed by GC–MS. Recoveries of carbendazim, Thiabendazole and thiophanate-methyl at four fortification levels (0.5, 1.0, 2.5 and 4.0 mg/kg) were in the range 81–96% for carbendazim and Thiabendazole and 63.2–69.8% for thiophanate-methyl. Only two samples contained carbendazim that exceeded the FAO/WHO Codex Alimentarius and the Italian Department of Health maximum residue limits.
