The Experts below are selected from a list of 2703 Experts worldwide ranked by ideXlab platform
Yongping Gao - One of the best experts on this subject based on the ideXlab platform.
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detection of ag ions via an anti aggregation mechanism using unmodified gold nanoparticles in the presence of Thiamazole
Talanta, 2021Co-Authors: Lihui Mao, Qianqian Wang, Yuhao Luo, Yongping GaoAbstract:Abstract: The present study proposed a novel and highly selective and sensitive method for Ag+ ion detection based on gold nanoparticles (AuNPs) anti-aggregation. Thiamazole can induce AuNPs aggregation due to electrostatic interactions, which result in color transitions in the AuNPs solution from red to blue. However, the presence of Ag+ ions results in the preferential combination of the pyridinic nitrogen of Thiamazole with the Ag+ ions. In addition, the Ag+ ions oxidize the sulfhydryl groups(-SH), which inhibit AuNPs aggregation and prompt a color change from blue to red. As a result, the present study established a method for Ag+ ion determination by AuNPs-Thiamazole colorimetric probe based on the aforementioned anti-aggregation mechanism. The probe dynamic range was easily tuned via adjustments of the Thiamazole amount. The relationship between the Ag+ concentration and AuNPs aggregation was monitored by ultraviolet-visible light (UV-Vis) spectroscopy at a dynamic range of 0.1 nM to 9 μM and at a detection limit of 0.042 nM. The river water and tap water recovery analysis validated the successful operation of this colorimetric sensor in environmental monitoring.
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Detection of Ag+ ions via an anti-aggregation mechanism using unmodified gold nanoparticles in the presence of Thiamazole.
Talanta, 2020Co-Authors: Lihui Mao, Wang Qianqian, Luo Yuhao, Yongping GaoAbstract:Abstract: The present study proposed a novel and highly selective and sensitive method for Ag+ ion detection based on gold nanoparticles (AuNPs) anti-aggregation. Thiamazole can induce AuNPs aggregation due to electrostatic interactions, which result in color transitions in the AuNPs solution from red to blue. However, the presence of Ag+ ions results in the preferential combination of the pyridinic nitrogen of Thiamazole with the Ag+ ions. In addition, the Ag+ ions oxidize the sulfhydryl groups(-SH), which inhibit AuNPs aggregation and prompt a color change from blue to red. As a result, the present study established a method for Ag+ ion determination by AuNPs-Thiamazole colorimetric probe based on the aforementioned anti-aggregation mechanism. The probe dynamic range was easily tuned via adjustments of the Thiamazole amount. The relationship between the Ag+ concentration and AuNPs aggregation was monitored by ultraviolet-visible light (UV-Vis) spectroscopy at a dynamic range of 0.1 nM to 9 μM and at a detection limit of 0.042 nM. The river water and tap water recovery analysis validated the successful operation of this colorimetric sensor in environmental monitoring.
R Tummersde Lind F Van Wijngaarden - One of the best experts on this subject based on the ideXlab platform.
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an uncommon side effect of Thiamazole treatment in graves disease
Netherlands Journal of Medicine, 2020Co-Authors: D Van Moorsel, R Tummersde Lind F Van WijngaardenAbstract:Thionamides (such as Thiamazole/methimazole) are a common first line treatment for Graves' disease. Common side effects include rash, urticaria, and arthralgia. However, thionamide treatment has also been associated with a variety of auto-immune syndromes. Here, we describe a patient presenting with mild arthritis after starting Thiamazole. Although severe presentation warrants acute withdrawal of the causative agent, our case suggests that milder forms can be successfully treated with anti-inflammatory drugs alone. Recognition of the syndrome is key to warrant timely and effective treatment.
Lihui Mao - One of the best experts on this subject based on the ideXlab platform.
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detection of ag ions via an anti aggregation mechanism using unmodified gold nanoparticles in the presence of Thiamazole
Talanta, 2021Co-Authors: Lihui Mao, Qianqian Wang, Yuhao Luo, Yongping GaoAbstract:Abstract: The present study proposed a novel and highly selective and sensitive method for Ag+ ion detection based on gold nanoparticles (AuNPs) anti-aggregation. Thiamazole can induce AuNPs aggregation due to electrostatic interactions, which result in color transitions in the AuNPs solution from red to blue. However, the presence of Ag+ ions results in the preferential combination of the pyridinic nitrogen of Thiamazole with the Ag+ ions. In addition, the Ag+ ions oxidize the sulfhydryl groups(-SH), which inhibit AuNPs aggregation and prompt a color change from blue to red. As a result, the present study established a method for Ag+ ion determination by AuNPs-Thiamazole colorimetric probe based on the aforementioned anti-aggregation mechanism. The probe dynamic range was easily tuned via adjustments of the Thiamazole amount. The relationship between the Ag+ concentration and AuNPs aggregation was monitored by ultraviolet-visible light (UV-Vis) spectroscopy at a dynamic range of 0.1 nM to 9 μM and at a detection limit of 0.042 nM. The river water and tap water recovery analysis validated the successful operation of this colorimetric sensor in environmental monitoring.
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Detection of Ag+ ions via an anti-aggregation mechanism using unmodified gold nanoparticles in the presence of Thiamazole.
Talanta, 2020Co-Authors: Lihui Mao, Wang Qianqian, Luo Yuhao, Yongping GaoAbstract:Abstract: The present study proposed a novel and highly selective and sensitive method for Ag+ ion detection based on gold nanoparticles (AuNPs) anti-aggregation. Thiamazole can induce AuNPs aggregation due to electrostatic interactions, which result in color transitions in the AuNPs solution from red to blue. However, the presence of Ag+ ions results in the preferential combination of the pyridinic nitrogen of Thiamazole with the Ag+ ions. In addition, the Ag+ ions oxidize the sulfhydryl groups(-SH), which inhibit AuNPs aggregation and prompt a color change from blue to red. As a result, the present study established a method for Ag+ ion determination by AuNPs-Thiamazole colorimetric probe based on the aforementioned anti-aggregation mechanism. The probe dynamic range was easily tuned via adjustments of the Thiamazole amount. The relationship between the Ag+ concentration and AuNPs aggregation was monitored by ultraviolet-visible light (UV-Vis) spectroscopy at a dynamic range of 0.1 nM to 9 μM and at a detection limit of 0.042 nM. The river water and tap water recovery analysis validated the successful operation of this colorimetric sensor in environmental monitoring.
D Van Moorsel - One of the best experts on this subject based on the ideXlab platform.
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an uncommon side effect of Thiamazole treatment in graves disease
Netherlands Journal of Medicine, 2020Co-Authors: D Van Moorsel, R Tummersde Lind F Van WijngaardenAbstract:Thionamides (such as Thiamazole/methimazole) are a common first line treatment for Graves' disease. Common side effects include rash, urticaria, and arthralgia. However, thionamide treatment has also been associated with a variety of auto-immune syndromes. Here, we describe a patient presenting with mild arthritis after starting Thiamazole. Although severe presentation warrants acute withdrawal of the causative agent, our case suggests that milder forms can be successfully treated with anti-inflammatory drugs alone. Recognition of the syndrome is key to warrant timely and effective treatment.
Ikuo Inoue - One of the best experts on this subject based on the ideXlab platform.
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Administration of Thiamazole for Graves' disease might trigger the onset of type 1 diabetes.
Journal of diabetes investigation, 2018Co-Authors: Mizutani, Yusuke Hikima, Atsushi Satomura, Takujiro Iuchi, Ritsuko Nakajima, Yumi Miyashita, Shigemitsu Yasuda, Yoichi Oikawa, Masashi Isshiki, Ikuo InoueAbstract:Thiamazole might trigger the onset of type 1 diabetes.
