The Experts below are selected from a list of 369 Experts worldwide ranked by ideXlab platform
B A Trofimov - One of the best experts on this subject based on the ideXlab platform.
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structural reorganization of allyl benzyl and propargylsulfanyl substituted 2 aza 1 3 5 trienes in t buok thf dmso access to rare functionalized 2 Thiazolines
ChemInform, 2014Co-Authors: N. A. Nedolya, O A Tarasova, A I Albanov, B A TrofimovAbstract:Different rare functionalized Thiazolines along with azepine derivatives are obtained by treatment of substrates (I), (IV), and (VII) with KOtBu.
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structural reorganization of allyl benzyl and propargylsulfanyl substituted 2 aza 1 3 5 trienes in t buok thf dmso access to rare functionalized 2 Thiazolines
Tetrahedron Letters, 2014Co-Authors: N. A. Nedolya, O A Tarasova, A I Albanov, B A TrofimovAbstract:Abstract Treatment of (allyl-, benzyl-, and propargylsulfanyl)-substituted 2-aza-1,3,5-trienes, which are readily accessible from lithiated methoxyallene, isopropyl isothiocyanate, and allyl, benzyl, or propargyl bromide, respectively, with t-BuOK in THF/DMSO resulted in the unexpected formation of 2-thiazoline derivatives along with seven-membered azaheterocycles [in the case of (allyl- and benzylsulfanyl)-substituted 2-aza-1,3,5-trienes]. An unprecedented structural reorganization of the azatrienes into 2-Thiazolines presumably occurs via α-deprotonation of the substituents at the sulfur atom followed by intramolecular [1,5]-cyclization. Deprotonation of the ketimine fragment of the same molecule followed by [1,7]-electrocyclization resulted in azepine ring formation.
Dennis Bigg - One of the best experts on this subject based on the ideXlab platform.
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preparation of 2 β oxo 2 oxazolines and Thiazolines by reaction of enamines with 2 chloroethyl iso thio cyanates
Synthesis, 1993Co-Authors: Florence Castan, Frederic Denonne, Dennis BiggAbstract:Pyrrolidino enamines react with 2-chloroethyl iso(thio)cyanate to give, after hydrolysis, 2-(beta-oxo)-2-oxazolines and Thiazolines in fair to good overall yield.
N. A. Nedolya - One of the best experts on this subject based on the ideXlab platform.
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structural reorganization of allyl benzyl and propargylsulfanyl substituted 2 aza 1 3 5 trienes in t buok thf dmso access to rare functionalized 2 Thiazolines
ChemInform, 2014Co-Authors: N. A. Nedolya, O A Tarasova, A I Albanov, B A TrofimovAbstract:Different rare functionalized Thiazolines along with azepine derivatives are obtained by treatment of substrates (I), (IV), and (VII) with KOtBu.
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structural reorganization of allyl benzyl and propargylsulfanyl substituted 2 aza 1 3 5 trienes in t buok thf dmso access to rare functionalized 2 Thiazolines
Tetrahedron Letters, 2014Co-Authors: N. A. Nedolya, O A Tarasova, A I Albanov, B A TrofimovAbstract:Abstract Treatment of (allyl-, benzyl-, and propargylsulfanyl)-substituted 2-aza-1,3,5-trienes, which are readily accessible from lithiated methoxyallene, isopropyl isothiocyanate, and allyl, benzyl, or propargyl bromide, respectively, with t-BuOK in THF/DMSO resulted in the unexpected formation of 2-thiazoline derivatives along with seven-membered azaheterocycles [in the case of (allyl- and benzylsulfanyl)-substituted 2-aza-1,3,5-trienes]. An unprecedented structural reorganization of the azatrienes into 2-Thiazolines presumably occurs via α-deprotonation of the substituents at the sulfur atom followed by intramolecular [1,5]-cyclization. Deprotonation of the ketimine fragment of the same molecule followed by [1,7]-electrocyclization resulted in azepine ring formation.
Florence Castan - One of the best experts on this subject based on the ideXlab platform.
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preparation of 2 β oxo 2 oxazolines and Thiazolines by reaction of enamines with 2 chloroethyl iso thio cyanates
Synthesis, 1993Co-Authors: Florence Castan, Frederic Denonne, Dennis BiggAbstract:Pyrrolidino enamines react with 2-chloroethyl iso(thio)cyanate to give, after hydrolysis, 2-(beta-oxo)-2-oxazolines and Thiazolines in fair to good overall yield.
Jun Liu - One of the best experts on this subject based on the ideXlab platform.
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concise synthesis of 2 4 disubstituted thiazoles from β azido disulfides and carboxylic acids or anhydrides asymmetric synthesis of cystothiazole c
ChemInform, 2015Co-Authors: Yi Liu, Xue Sun, Xing Zhang, Jun LiuAbstract:A novel and efficient method for the synthesis of a series of 2,4-disubstituted thiazoles (III) and (V) by reaction of β-azido disulfides (I) with anhydrides or carboxylic acids and subsequent oxidative dehydrogenation of intermediate Thiazolines is developed.
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one pot synthesis of 2 4 disubstituted thiazoline from β azido disulfide and carboxylic acid
ChemInform, 2012Co-Authors: Yi Liu, Jun LiuAbstract:It provides a facile and efficient method to prepare disubstituted Thiazolines which are of biological interest.
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one pot synthesis of 2 4 disubstituted thiazoline from β azido disulfide and carboxylic acid
Journal of Organic Chemistry, 2012Co-Authors: Yi Liu, Jun LiuAbstract:A concise and efficient one-pot four-step synthesis of 2,4-disubstituted thiazoline via a cascade disulfide bond cleavage/thiocarbonylation/Staudinger reduction/aza-Wittig reaction is established. Treatment of various carboxylic acids with β-azido disulfides under this one-pot procedure obtained the desired Thiazolines in good to excellent isolated yields.
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One-Pot Synthesis of 2,4-Disubstituted Thiazoline from β‑Azido Disulfide and Carboxylic Acid
2012Co-Authors: Yi Liu, Jun LiuAbstract:A concise and efficient one-pot four-step synthesis of 2,4-disubstituted thiazoline via a cascade disulfide bond cleavage/thiocarbonylation/Staudinger reduction/aza-Wittig reaction is established. Treatment of various carboxylic acids with β-azido disulfides under this one-pot procedure obtained the desired Thiazolines in good to excellent isolated yields