The Experts below are selected from a list of 42 Experts worldwide ranked by ideXlab platform
Carmen Quintana - One of the best experts on this subject based on the ideXlab platform.
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a 2d tungsten disulphide diamond nanoparticles hybrid for an electrochemical sensor development towards the simultaneous determination of sunset yellow and quinoline yellow
Sensors and Actuators B-chemical, 2020Co-Authors: Elías Blanco, Lina Hristova, Luis Vázquez, Gary Ellis, L. Sánchez, María Del Pozo, Elena Casero, Rut Martinezmoro, Maria Dolores Petitdominguez, Carmen QuintanaAbstract:Abstract We present the development of an electrochemical sensor towards the simultaneous analysis of a mixture of food additives: sunset yellow (SY) and quinoline yellow (QY) dyes. The sensor is based on the synergetic effect observed between diamond nanoparticles (DNPs) and WS2 nanosheets obtained by liquid exfoliation. The prepared TMDs were characterized using Raman spectroscopy, X-Ray Diffraction (XRD) and Atomic Force Microscopy (AFM). The AFM characterization showed isolated WS2 flakes with different lateral dimensions scattered over the flat background. The combination of WS2 and DNPs allows resolution of the oxidation signals of the analytes, which overlap working with the bare glassy carbon (GC) electrode. The best electroanalytical response was obtained with a sensor containing both nanomaterials deposited employing the drop-casting method in a sequential manner, a first layer of WS2 and a second layer of DNPs (GC/WS2/DNPs). Electrochemical impedance spectroscopy experiments showed that for the GC/WS2/DNPs system the charge transfer is clearly improved. Under optimized differential pulse voltammetry conditions, the GC/WS2/DNPs sensor allows the determination of SY at +100 mV and QY at +850 mV with detection limits of 0.086 and 3.4 μM respectively, with relative errors ≤ 8.40 % and a relative standard deviation ≤ 12.6 %. The proposed methodology was applied to the determination of SY and QY in commercial Throat Lozenge samples with very good recoveries on average: 93 %, for QY and 106 % for SY.
Elías Blanco - One of the best experts on this subject based on the ideXlab platform.
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a 2d tungsten disulphide diamond nanoparticles hybrid for an electrochemical sensor development towards the simultaneous determination of sunset yellow and quinoline yellow
Sensors and Actuators B-chemical, 2020Co-Authors: Elías Blanco, Lina Hristova, Luis Vázquez, Gary Ellis, L. Sánchez, María Del Pozo, Elena Casero, Rut Martinezmoro, Maria Dolores Petitdominguez, Carmen QuintanaAbstract:Abstract We present the development of an electrochemical sensor towards the simultaneous analysis of a mixture of food additives: sunset yellow (SY) and quinoline yellow (QY) dyes. The sensor is based on the synergetic effect observed between diamond nanoparticles (DNPs) and WS2 nanosheets obtained by liquid exfoliation. The prepared TMDs were characterized using Raman spectroscopy, X-Ray Diffraction (XRD) and Atomic Force Microscopy (AFM). The AFM characterization showed isolated WS2 flakes with different lateral dimensions scattered over the flat background. The combination of WS2 and DNPs allows resolution of the oxidation signals of the analytes, which overlap working with the bare glassy carbon (GC) electrode. The best electroanalytical response was obtained with a sensor containing both nanomaterials deposited employing the drop-casting method in a sequential manner, a first layer of WS2 and a second layer of DNPs (GC/WS2/DNPs). Electrochemical impedance spectroscopy experiments showed that for the GC/WS2/DNPs system the charge transfer is clearly improved. Under optimized differential pulse voltammetry conditions, the GC/WS2/DNPs sensor allows the determination of SY at +100 mV and QY at +850 mV with detection limits of 0.086 and 3.4 μM respectively, with relative errors ≤ 8.40 % and a relative standard deviation ≤ 12.6 %. The proposed methodology was applied to the determination of SY and QY in commercial Throat Lozenge samples with very good recoveries on average: 93 %, for QY and 106 % for SY.
Adrian Shephard - One of the best experts on this subject based on the ideXlab platform.
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inhibition of viral and bacterial trigger stimulated prostaglandin e2 by a Throat Lozenge containing flurbiprofen an in vitro study using a human respiratory epithelial cell line
Sage Open Medicine, 2020Co-Authors: Rob Lambkinwilliams, Alex Mann, Adrian ShephardAbstract:Objectives:Symptoms of sore Throat result from oropharyngeal inflammation, for which prostaglandin E2 is a key mediator. Flurbiprofen is a non-steroidal anti-inflammatory that provides sore Throat ...
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a multicentre randomised double blind single dose study assessing the efficacy of amc dcba warm Lozenge or amc dcba cool Lozenge in the relief of acute sore Throat
BMC Family Practice, 2011Co-Authors: Alan G Wade, Christopher Morris, Adrian Shephard, Gordon M Crawford, Michael GoulderAbstract:Background Clinically proven over-the-counter (OTC) treatment options are becoming increasingly important in the self-management of acute sore Throat. The aim of this study was to determine the analgesic and sensorial benefits of two different amylmetacresol/2,4-dichlorobenzyl alcohol (AMC/DCBA) Throat Lozenge formulation variants, AMC/DCBA Warm Lozenge and AMC/DCBA Cool Lozenge, compared with an unflavoured, non-medicated placebo Lozenge in the relief of acute sore Throat due to upper respiratory tract infections.
Rut Martinezmoro - One of the best experts on this subject based on the ideXlab platform.
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a 2d tungsten disulphide diamond nanoparticles hybrid for an electrochemical sensor development towards the simultaneous determination of sunset yellow and quinoline yellow
Sensors and Actuators B-chemical, 2020Co-Authors: Elías Blanco, Lina Hristova, Luis Vázquez, Gary Ellis, L. Sánchez, María Del Pozo, Elena Casero, Rut Martinezmoro, Maria Dolores Petitdominguez, Carmen QuintanaAbstract:Abstract We present the development of an electrochemical sensor towards the simultaneous analysis of a mixture of food additives: sunset yellow (SY) and quinoline yellow (QY) dyes. The sensor is based on the synergetic effect observed between diamond nanoparticles (DNPs) and WS2 nanosheets obtained by liquid exfoliation. The prepared TMDs were characterized using Raman spectroscopy, X-Ray Diffraction (XRD) and Atomic Force Microscopy (AFM). The AFM characterization showed isolated WS2 flakes with different lateral dimensions scattered over the flat background. The combination of WS2 and DNPs allows resolution of the oxidation signals of the analytes, which overlap working with the bare glassy carbon (GC) electrode. The best electroanalytical response was obtained with a sensor containing both nanomaterials deposited employing the drop-casting method in a sequential manner, a first layer of WS2 and a second layer of DNPs (GC/WS2/DNPs). Electrochemical impedance spectroscopy experiments showed that for the GC/WS2/DNPs system the charge transfer is clearly improved. Under optimized differential pulse voltammetry conditions, the GC/WS2/DNPs sensor allows the determination of SY at +100 mV and QY at +850 mV with detection limits of 0.086 and 3.4 μM respectively, with relative errors ≤ 8.40 % and a relative standard deviation ≤ 12.6 %. The proposed methodology was applied to the determination of SY and QY in commercial Throat Lozenge samples with very good recoveries on average: 93 %, for QY and 106 % for SY.
Lina Hristova - One of the best experts on this subject based on the ideXlab platform.
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a 2d tungsten disulphide diamond nanoparticles hybrid for an electrochemical sensor development towards the simultaneous determination of sunset yellow and quinoline yellow
Sensors and Actuators B-chemical, 2020Co-Authors: Elías Blanco, Lina Hristova, Luis Vázquez, Gary Ellis, L. Sánchez, María Del Pozo, Elena Casero, Rut Martinezmoro, Maria Dolores Petitdominguez, Carmen QuintanaAbstract:Abstract We present the development of an electrochemical sensor towards the simultaneous analysis of a mixture of food additives: sunset yellow (SY) and quinoline yellow (QY) dyes. The sensor is based on the synergetic effect observed between diamond nanoparticles (DNPs) and WS2 nanosheets obtained by liquid exfoliation. The prepared TMDs were characterized using Raman spectroscopy, X-Ray Diffraction (XRD) and Atomic Force Microscopy (AFM). The AFM characterization showed isolated WS2 flakes with different lateral dimensions scattered over the flat background. The combination of WS2 and DNPs allows resolution of the oxidation signals of the analytes, which overlap working with the bare glassy carbon (GC) electrode. The best electroanalytical response was obtained with a sensor containing both nanomaterials deposited employing the drop-casting method in a sequential manner, a first layer of WS2 and a second layer of DNPs (GC/WS2/DNPs). Electrochemical impedance spectroscopy experiments showed that for the GC/WS2/DNPs system the charge transfer is clearly improved. Under optimized differential pulse voltammetry conditions, the GC/WS2/DNPs sensor allows the determination of SY at +100 mV and QY at +850 mV with detection limits of 0.086 and 3.4 μM respectively, with relative errors ≤ 8.40 % and a relative standard deviation ≤ 12.6 %. The proposed methodology was applied to the determination of SY and QY in commercial Throat Lozenge samples with very good recoveries on average: 93 %, for QY and 106 % for SY.