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R. A. Hill - One of the best experts on this subject based on the ideXlab platform.

  • SLIPPED UPPER Tibial Epiphysis CAUSING TIBIA VARA: A STUDY OF THREE CASES FROM THREE CENTRES
    2018
    Co-Authors: A. P. Sanghrajka, C. F. Murnaghan, Bellemore M, H Simpson, R. A. Hill
    Abstract:

    IntroductionWe report 3 cases from different centres of infantile tibia vara in which the deformity was due to slippage of the proximal Tibial Epiphysis on the metaphysis; the aim of this study was to define the features of this previously unreported condition, and their implications for management.MethodThree cases of tibia vara secondary to atraumatic slippage of the upper Tibial Epiphysis on the metaphysis were identified from three different centres. The case notes and imaging studies were retrospectively reviewed to distinguish common clinical and radiographic features.ResultsThere were one male and two females, all of non-Caucasian origin, (age 3–7 years). All patients' weights were above the 97th centile for age. In all cases there was an infero-medial subluxation of the Tibial Epiphysis over a dome shaped proximal Tibial metaphysis, with disruption of continuity between their lateral borders. The height of the medial Tibial plateau was preserved in all cases.New bone formation suggests this is a c...

  • SLIPPED UPPER Tibial Epiphysis CAUSING TIBIA VARA: A STUDY OF THREE CASES FROM THREE CENTRES
    Journal of Bone and Joint Surgery-british Volume, 2013
    Co-Authors: A. P. Sanghrajka, C. F. Murnaghan, Bellemore M, H Simpson, R. A. Hill
    Abstract:

    Introduction We report 3 cases from different centres of infantile tibia vara in which the deformity was due to slippage of the proximal Tibial Epiphysis on the metaphysis; the aim of this study was to define the features of this previously unreported condition, and their implications for management. Method Three cases of tibia vara secondary to atraumatic slippage of the upper Tibial Epiphysis on the metaphysis were identified from three different centres. The case notes and imaging studies were retrospectively reviewed to distinguish common clinical and radiographic features. Results There were one male and two females, all of non-Caucasian origin, (age 3–7 years). All patients9 weights were above the 97th centile for age. In all cases there was an infero-medial subluxation of the Tibial Epiphysis over a dome shaped proximal Tibial metaphysis, with disruption of continuity between their lateral borders. The height of the medial Tibial plateau was preserved in all cases. New bone formation suggests this is a chronic process. The evolution of one case indicates that pathogenesis is shared with infantile Blount9s disease. A gradual deformity correction was performed in all cases using circular external fixation, with the proximal ring secured to both the proximal Epiphysis and metaphysis. Conclusion Slipped upper Tibial Epiphysis is an uncommon but distinct cause of tibia vara. The radiological features are completely different from those previously described for infantile tibia vara and not encompassed by the existing classification. The unusual morphology has consequences for treatment. Management is analogous to a slipped upper femoral Epiphysis – the physis has to be stabilized to the metaphysis and an osteotomy performed to restore the mechanical axis. We believe this is best achieved with a circular external fixator because this permits multiaxial correction including translation and rotation.

  • Slipped upper Tibial Epiphysis in infantile tibia vara: Three cases
    The Journal of bone and joint surgery. British volume, 2012
    Co-Authors: A. P. Sanghrajka, R. A. Hill, C. F. Murnaghan, A. H. R. W. Simpson, Bellemore M
    Abstract:

    We describe three cases of infantile tibia vara resulting from an atraumatic slip of the proximal Tibial Epiphysis upon the metaphysis. There appears to be an association between this condition and severe obesity. Radiologically, the condition is characterised by a dome-shaped metaphysis, an open growth plate and disruption of the continuity between the lateral borders of the Epiphysis and metaphysis, with inferomedial translation of the proximal Tibial Epiphysis. All patients were treated by realignment of the proximal tibia by distraction osteogenesis with an external circulator fixator, and it is suggested that this is the optimal method for correction of this complex deformity. There are differences in the radiological features and management between conventional infantile Blount’s disease and this ‘slipped upper Tibial Epiphysis’ variant.

Cemal Kazimoglu - One of the best experts on this subject based on the ideXlab platform.

  • forensic age estimation via 3 t magnetic resonance imaging of ossification of the proximal Tibial and distal femoral epiphyses use of a t2 weighted fast spin echo technique
    Forensic Science International, 2016
    Co-Authors: Oguzhan Ekizoglu, Elif Hocaoglu, Ercan Inci, Ismail Ozgur Can, Sema Aksoy, Cemal Kazimoglu
    Abstract:

    Abstract Radiation exposure during forensic age estimation is associated with ethical implications. It is important to prevent repetitive radiation exposure when conducting advanced ultrasonography (USG) and magnetic resonance imaging (MRI). The purpose of this study was to investigate the utility of 3.0-T MRI in determining the degree of ossification of the distal femoral and proximal Tibial epiphyses in a group of Turkish population. We retrospectively evaluated coronal T2-weighted and turbo spin-echo sequences taken upon MRI of 503 patients (305 males, 198 females; age 10–30 years) using a five-stage method. Intra- and interobserver variations were very low. (Intraobserver reliability was κ  = 0.919 for the distal femoral Epiphysis and κ  = 0.961 for the proximal Tibial Epiphysis, and interobserver reliability was κ  = 0.836 for the distal femoral Epiphysis and κ  = 0.885 for the proximal Tibial Epiphysis.) Spearman's rank correlation analysis indicated a significant positive relationship between age and the extent of ossification of the distal femoral and proximal Tibial epiphyses ( p p MRI of the distal femoral and proximal Tibial epiphyses is an alternative, noninvasive, and reliable technique to estimate age.

  • Forensic age estimation via 3-T magnetic resonance imaging of ossification of the proximal Tibial and distal femoral epiphyses: Use of a T2-weighted fast spin-echo technique.
    Forensic science international, 2015
    Co-Authors: Oguzhan Ekizoglu, Elif Hocaoglu, Ercan Inci, Ismail Ozgur Can, Sema Aksoy, Cemal Kazimoglu
    Abstract:

    Radiation exposure during forensic age estimation is associated with ethical implications. It is important to prevent repetitive radiation exposure when conducting advanced ultrasonography (USG) and magnetic resonance imaging (MRI). The purpose of this study was to investigate the utility of 3.0-T MRI in determining the degree of ossification of the distal femoral and proximal Tibial epiphyses in a group of Turkish population. We retrospectively evaluated coronal T2-weighted and turbo spin-echo sequences taken upon MRI of 503 patients (305 males, 198 females; age 10-30 years) using a five-stage method. Intra- and interobserver variations were very low. (Intraobserver reliability was κ=0.919 for the distal femoral Epiphysis and κ=0.961 for the proximal Tibial Epiphysis, and interobserver reliability was κ=0.836 for the distal femoral Epiphysis and κ=0.885 for the proximal Tibial Epiphysis.) Spearman's rank correlation analysis indicated a significant positive relationship between age and the extent of ossification of the distal femoral and proximal Tibial epiphyses (p

Bellemore M - One of the best experts on this subject based on the ideXlab platform.

  • SLIPPED UPPER Tibial Epiphysis CAUSING TIBIA VARA: A STUDY OF THREE CASES FROM THREE CENTRES
    2018
    Co-Authors: A. P. Sanghrajka, C. F. Murnaghan, Bellemore M, H Simpson, R. A. Hill
    Abstract:

    IntroductionWe report 3 cases from different centres of infantile tibia vara in which the deformity was due to slippage of the proximal Tibial Epiphysis on the metaphysis; the aim of this study was to define the features of this previously unreported condition, and their implications for management.MethodThree cases of tibia vara secondary to atraumatic slippage of the upper Tibial Epiphysis on the metaphysis were identified from three different centres. The case notes and imaging studies were retrospectively reviewed to distinguish common clinical and radiographic features.ResultsThere were one male and two females, all of non-Caucasian origin, (age 3–7 years). All patients' weights were above the 97th centile for age. In all cases there was an infero-medial subluxation of the Tibial Epiphysis over a dome shaped proximal Tibial metaphysis, with disruption of continuity between their lateral borders. The height of the medial Tibial plateau was preserved in all cases.New bone formation suggests this is a c...

  • SLIPPED UPPER Tibial Epiphysis CAUSING TIBIA VARA: A STUDY OF THREE CASES FROM THREE CENTRES
    Journal of Bone and Joint Surgery-british Volume, 2013
    Co-Authors: A. P. Sanghrajka, C. F. Murnaghan, Bellemore M, H Simpson, R. A. Hill
    Abstract:

    Introduction We report 3 cases from different centres of infantile tibia vara in which the deformity was due to slippage of the proximal Tibial Epiphysis on the metaphysis; the aim of this study was to define the features of this previously unreported condition, and their implications for management. Method Three cases of tibia vara secondary to atraumatic slippage of the upper Tibial Epiphysis on the metaphysis were identified from three different centres. The case notes and imaging studies were retrospectively reviewed to distinguish common clinical and radiographic features. Results There were one male and two females, all of non-Caucasian origin, (age 3–7 years). All patients9 weights were above the 97th centile for age. In all cases there was an infero-medial subluxation of the Tibial Epiphysis over a dome shaped proximal Tibial metaphysis, with disruption of continuity between their lateral borders. The height of the medial Tibial plateau was preserved in all cases. New bone formation suggests this is a chronic process. The evolution of one case indicates that pathogenesis is shared with infantile Blount9s disease. A gradual deformity correction was performed in all cases using circular external fixation, with the proximal ring secured to both the proximal Epiphysis and metaphysis. Conclusion Slipped upper Tibial Epiphysis is an uncommon but distinct cause of tibia vara. The radiological features are completely different from those previously described for infantile tibia vara and not encompassed by the existing classification. The unusual morphology has consequences for treatment. Management is analogous to a slipped upper femoral Epiphysis – the physis has to be stabilized to the metaphysis and an osteotomy performed to restore the mechanical axis. We believe this is best achieved with a circular external fixator because this permits multiaxial correction including translation and rotation.

  • Slipped upper Tibial Epiphysis in infantile tibia vara: Three cases
    The Journal of bone and joint surgery. British volume, 2012
    Co-Authors: A. P. Sanghrajka, R. A. Hill, C. F. Murnaghan, A. H. R. W. Simpson, Bellemore M
    Abstract:

    We describe three cases of infantile tibia vara resulting from an atraumatic slip of the proximal Tibial Epiphysis upon the metaphysis. There appears to be an association between this condition and severe obesity. Radiologically, the condition is characterised by a dome-shaped metaphysis, an open growth plate and disruption of the continuity between the lateral borders of the Epiphysis and metaphysis, with inferomedial translation of the proximal Tibial Epiphysis. All patients were treated by realignment of the proximal tibia by distraction osteogenesis with an external circulator fixator, and it is suggested that this is the optimal method for correction of this complex deformity. There are differences in the radiological features and management between conventional infantile Blount’s disease and this ‘slipped upper Tibial Epiphysis’ variant.

A. P. Sanghrajka - One of the best experts on this subject based on the ideXlab platform.

  • SLIPPED UPPER Tibial Epiphysis CAUSING TIBIA VARA: A STUDY OF THREE CASES FROM THREE CENTRES
    2018
    Co-Authors: A. P. Sanghrajka, C. F. Murnaghan, Bellemore M, H Simpson, R. A. Hill
    Abstract:

    IntroductionWe report 3 cases from different centres of infantile tibia vara in which the deformity was due to slippage of the proximal Tibial Epiphysis on the metaphysis; the aim of this study was to define the features of this previously unreported condition, and their implications for management.MethodThree cases of tibia vara secondary to atraumatic slippage of the upper Tibial Epiphysis on the metaphysis were identified from three different centres. The case notes and imaging studies were retrospectively reviewed to distinguish common clinical and radiographic features.ResultsThere were one male and two females, all of non-Caucasian origin, (age 3–7 years). All patients' weights were above the 97th centile for age. In all cases there was an infero-medial subluxation of the Tibial Epiphysis over a dome shaped proximal Tibial metaphysis, with disruption of continuity between their lateral borders. The height of the medial Tibial plateau was preserved in all cases.New bone formation suggests this is a c...

  • SLIPPED UPPER Tibial Epiphysis CAUSING TIBIA VARA: A STUDY OF THREE CASES FROM THREE CENTRES
    Journal of Bone and Joint Surgery-british Volume, 2013
    Co-Authors: A. P. Sanghrajka, C. F. Murnaghan, Bellemore M, H Simpson, R. A. Hill
    Abstract:

    Introduction We report 3 cases from different centres of infantile tibia vara in which the deformity was due to slippage of the proximal Tibial Epiphysis on the metaphysis; the aim of this study was to define the features of this previously unreported condition, and their implications for management. Method Three cases of tibia vara secondary to atraumatic slippage of the upper Tibial Epiphysis on the metaphysis were identified from three different centres. The case notes and imaging studies were retrospectively reviewed to distinguish common clinical and radiographic features. Results There were one male and two females, all of non-Caucasian origin, (age 3–7 years). All patients9 weights were above the 97th centile for age. In all cases there was an infero-medial subluxation of the Tibial Epiphysis over a dome shaped proximal Tibial metaphysis, with disruption of continuity between their lateral borders. The height of the medial Tibial plateau was preserved in all cases. New bone formation suggests this is a chronic process. The evolution of one case indicates that pathogenesis is shared with infantile Blount9s disease. A gradual deformity correction was performed in all cases using circular external fixation, with the proximal ring secured to both the proximal Epiphysis and metaphysis. Conclusion Slipped upper Tibial Epiphysis is an uncommon but distinct cause of tibia vara. The radiological features are completely different from those previously described for infantile tibia vara and not encompassed by the existing classification. The unusual morphology has consequences for treatment. Management is analogous to a slipped upper femoral Epiphysis – the physis has to be stabilized to the metaphysis and an osteotomy performed to restore the mechanical axis. We believe this is best achieved with a circular external fixator because this permits multiaxial correction including translation and rotation.

  • Slipped upper Tibial Epiphysis in infantile tibia vara: Three cases
    The Journal of bone and joint surgery. British volume, 2012
    Co-Authors: A. P. Sanghrajka, R. A. Hill, C. F. Murnaghan, A. H. R. W. Simpson, Bellemore M
    Abstract:

    We describe three cases of infantile tibia vara resulting from an atraumatic slip of the proximal Tibial Epiphysis upon the metaphysis. There appears to be an association between this condition and severe obesity. Radiologically, the condition is characterised by a dome-shaped metaphysis, an open growth plate and disruption of the continuity between the lateral borders of the Epiphysis and metaphysis, with inferomedial translation of the proximal Tibial Epiphysis. All patients were treated by realignment of the proximal tibia by distraction osteogenesis with an external circulator fixator, and it is suggested that this is the optimal method for correction of this complex deformity. There are differences in the radiological features and management between conventional infantile Blount’s disease and this ‘slipped upper Tibial Epiphysis’ variant.

Dohyung Lim - One of the best experts on this subject based on the ideXlab platform.

  • Longitudinal Tracking of Alteration Pattern on Trabecular Bone Microarchitecture at Tibial Epiphysis Induced by Post Traumatic Osteoarthritis Over Time
    Transactions of the Korean Society of Mechanical Engineers B, 2012
    Co-Authors: Joo Hyung Lee, Keyoung Jin Chun, Han Sung Kim, Dae Jun Kim, Kwon-young Lee, Dohyung Lim
    Abstract:

    This study aims to track the longitudinal alteration pattern on the trabecular bone microarchitecture at Tibial Epiphysis induced by T-OA over time using in vivo micro computed tomography (). Ten SD rats were divided into control (n = 5) and T-OA (n = 5) groups. Anterior cruciate ligament transaction was performed for the T-OA group. The results showed that the alteration pattern on the trabecular bone microarchitecture at Tibial Epiphysis in the T.OA group was definitely different compared with that in the CON group from 0 to 8 weeks (approximately 4-16%, P > 0.05). In particular, a difference was observed in the bone formation and density distributions over time (from 0 or 4 to 8 weeks; approximately 5.15%, P

  • Changes in microarchitectural characteristics at the Tibial Epiphysis induced by collagen-induced rheumatoid arthritis over time
    Clinical interventions in aging, 2012
    Co-Authors: Joo Hyung Lee, Keyoung Jin Chun, Han Sung Kim, Sangho Kim, Kwon-yong Lee, Dae Jun Kim, Dohyung Lim
    Abstract:

    BACKGROUND Little is known about the time course of changes in the microarchitecture of the Tibial Epiphysis with rheumatoid arthritis (RA), although such information would be valuable in predicting risk of fracture. Therefore, we used in vivo microcomputed tomography (μ-CT) to assess patterns of microarchitectural alterations in the Tibial Epiphysis using collagen-induced RA in an animal model. METHODS Bovine type II collagen was injected intradermally into the tails of rats for induction of RA. The Tibial joints were scanned by in vivo μ-CT at 0, 4, and 8 weeks following injection. Microarchitectural parameters were measured to evaluate alteration patterns of bone microarchitecture at the Tibial Epiphysis. RESULTS The microarchitectural alterations in an RA group were significantly different from those in a control group from 0 to 4 weeks and from 4 to 8 weeks following injection (P < 0.05). The distribution of trabecular bone thickness and trabecular bone separation from 0 weeks to 8 weeks differed significantly (P < 0.05). CONCLUSION These results indicate that the patterns of microarchitectural alterations at the Tibial Epiphysis are strongly affected by collagen-induced progression of RA and entail a severe risk of fracture at the Tibial Epiphysis. This study represents a valuable first approach to tracking periodic and continuous changes in the microarchitectural characteristics of the Tibial Epiphysis with collagen-induced RA.

  • alteration of trabecular bone microarchitecure at Tibial Epiphysis due to knee joint instability by anterior cruciate ligament rupture difference between medial and lateral part
    Journal of Biomedical Engineering Research, 2012
    Co-Authors: Joo Hyung Lee, Keyoung Jin Chun, Han Sung Kim, Dohyung Lim
    Abstract:

    Knee joint instability by anterior cruciate ligament(ACL) rupture is allowing the abnormal loading condition at the Tibial Epiphysis locally, resulting in producing locally different bone bruise. The study examined difference between local alteration patterns of trabecular bone microarchitecture at medial and lateral parts of the Tibial Epiphysis by ACL rupture. Fourteen SD rats were divided into Control(CON; n