Tick-Borne Diseases

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Sylvia García-belenguer - One of the best experts on this subject based on the ideXlab platform.

  • The current status of major tick borne Diseases in Zambia
    Veterinary Research, 2003
    Co-Authors: Levi Hakwale Makala, Peter Mangani, María Pilar Pérez, Jorge Palacio, María Pilar Santolaria, María Del Carmen Aceña, Gema Chacón, Jorge Hugo Calvo, María Pilar Zaragoza, M Teresa Verde, Kozo Fujisaki, Manuel Gascón, Hideyuki Nagasawa, Sylvia García-belenguer
    Abstract:

    Tick-Borne Diseases occurring in Zambia are assuming more importance as they continue to be a major economic problem not only in Zambia, but in many parts of Eastern, Southern and Central Africa. The current control methods, which include the use of toxic acaricides to kill ticks, and the virulent sporozoite infection and treatment method have limitations. Recombinant vaccines, currently in their experimental stages, offer hope for the future. The use of acaricides is hampered by the development of acaricide resistance and live vaccines are dependent on cold chain facilities, which are a formidable obstacle in the poorly developed infrastructure in parts of Zambia where the vaccine is most needed. Amidst these drawbacks are the results of the recent research on parasites and vector recombinant vaccines which promise to circumvent these problems. The history, current status and attitudes regarding the control of these Diseases, taking into account their complexity, are reviewed. The establishment of the well-designed Central Veterinary Research Institute (CVRI) and Japanese International Cooperation Agency (JICA) sponsored veterinary school, both have a potential for high quality research, with access to a wealth of specimens a veritable goldmine of research material. It is thus hoped that this review will stimulate the desire to maximize the value of the tick and Tick-Borne disease research in both Zambia and the international research community.

Lidia Chițimia-dobler - One of the best experts on this subject based on the ideXlab platform.

  • Canine Tick-Borne Diseases in pet dogs from Romania.
    Parasites & vectors, 2017
    Co-Authors: Martin O. Andersson, Jonas Waldenström, Conny Tolf, Paula Tamba, Mircea Stefanache, Gerhard Dobler, Lidia Chițimia-dobler
    Abstract:

    Background Tick-Borne Diseases are of substantial concern worldwide for animals as well as humans. Dogs have been a human companion for millennia, and their significant impact on human life renders disease in dogs to be of great concern. Tick-Borne Diseases in dogs represent a substantial diagnostic challenge for veterinarians in that clinical signs are often diffuse and overlapping. In addition, co-infections with two or more pathogens enhance this problem further. Molecular methods are useful to disentangle co-infections and to accurately describe prevalence and geographical distribution of Tick-Borne Diseases. At this point, this information is lacking in many areas worldwide. Romania is one such area, where prevalence and distribution of several important pathogens need to be further investigated. To address this, we screened blood samples from 96 sick dogs with molecular methods for eight different pathogens including Babesia spp., Theileria spp., Hepatozoon spp., Anaplasma spp., Ehrlichia spp., “Candidatus Neoehrlichia mikurensis”, Mycoplasma spp., and Borrelia spp.

  • Canine Tick-Borne Diseases in pet dogs from Romania
    Parasites & Vectors, 2017
    Co-Authors: Martin O. Andersson, Jonas Waldenström, Conny Tolf, Paula Tamba, Mircea Stefanache, Gerhard Dobler, Lidia Chițimia-dobler
    Abstract:

    Background Tick-Borne Diseases are of substantial concern worldwide for animals as well as humans. Dogs have been a human companion for millennia, and their significant impact on human life renders disease in dogs to be of great concern. Tick-Borne Diseases in dogs represent a substantial diagnostic challenge for veterinarians in that clinical signs are often diffuse and overlapping. In addition, co-infections with two or more pathogens enhance this problem further. Molecular methods are useful to disentangle co-infections and to accurately describe prevalence and geographical distribution of Tick-Borne Diseases. At this point, this information is lacking in many areas worldwide. Romania is one such area, where prevalence and distribution of several important pathogens need to be further investigated. To address this, we screened blood samples from 96 sick dogs with molecular methods for eight different pathogens including Babesia spp., Theileria spp., Hepatozoon spp., Anaplasma spp., Ehrlichia spp., “ Candidatus Neoehrlichia mikurensis”, Mycoplasma spp., and Borrelia spp. Results As many as 45% (43/96) of the dogs in the study were infected with protozoan parasites. Babesia canis was the most frequent of these (28 infected dogs), whereas Hepatozoon canis was detected in 15% (14/96) and Babesia gibsoni was found in a single sample. Bacterial infection with Mycoplasma spp. occurred in 18% (17/96) of the sampled dogs. Obtained bacterial sequences revealed the occurrence of two species: Mycoplasma canis and “ Candidatus Mycoplasma haematoparvum”. In several cases co-infection with protozoan parasites and Mycoplasma sp. were detected. All dogs were negative for Anaplasma spp., Ehrlichia spp., “ Ca. Neoehrlichia mikurensis”, and for Borrelia spp . Conclusions The results from the present study reinforce the notion that Babesia canis is an important pathogen in the Romanian dog population. However, more surprisingly, another protozoan species, H. canis , seems to be infecting dogs to a larger extent than previously recognized in Romania. Well-known Tick-Borne bacterial disease agents such as Anaplasma spp. and Borrelia spp. were not detected. In contrast, less well-studied bacteria such as hemotropic Mycoplasma spp. were detected frequently. Moreover, co-infection might aggravate disease and complicate diagnosis and should be further studied in dogs.

Levi Hakwale Makala - One of the best experts on this subject based on the ideXlab platform.

  • The current status of major tick borne Diseases in Zambia
    Veterinary Research, 2003
    Co-Authors: Levi Hakwale Makala, Peter Mangani, María Pilar Pérez, Jorge Palacio, María Pilar Santolaria, María Del Carmen Aceña, Gema Chacón, Jorge Hugo Calvo, María Pilar Zaragoza, M Teresa Verde, Kozo Fujisaki, Manuel Gascón, Hideyuki Nagasawa, Sylvia García-belenguer
    Abstract:

    Tick-Borne Diseases occurring in Zambia are assuming more importance as they continue to be a major economic problem not only in Zambia, but in many parts of Eastern, Southern and Central Africa. The current control methods, which include the use of toxic acaricides to kill ticks, and the virulent sporozoite infection and treatment method have limitations. Recombinant vaccines, currently in their experimental stages, offer hope for the future. The use of acaricides is hampered by the development of acaricide resistance and live vaccines are dependent on cold chain facilities, which are a formidable obstacle in the poorly developed infrastructure in parts of Zambia where the vaccine is most needed. Amidst these drawbacks are the results of the recent research on parasites and vector recombinant vaccines which promise to circumvent these problems. The history, current status and attitudes regarding the control of these Diseases, taking into account their complexity, are reviewed. The establishment of the well-designed Central Veterinary Research Institute (CVRI) and Japanese International Cooperation Agency (JICA) sponsored veterinary school, both have a potential for high quality research, with access to a wealth of specimens a veritable goldmine of research material. It is thus hoped that this review will stimulate the desire to maximize the value of the tick and Tick-Borne disease research in both Zambia and the international research community.

Thomas R. Fritsche - One of the best experts on this subject based on the ideXlab platform.

  • Tick-Borne Diseases in the United States.
    The New England journal of medicine, 1993
    Co-Authors: David H. Spach, Thomas R. Fritsche
    Abstract:

    In the United States, more vector-borne Diseases are transmitted by ticks than by any other agent1. During the past 20 years, Tick-Borne Diseases have taken on increased importance as humans have moved into rural areas and increased their recreational outdoor activity. Tick-Borne Diseases can result from infection with pathogens that include bacteria, rickettsia, viruses, and protozoa (Table 1). In this article, we review recent advances in the understanding of these Diseases, particularly the microbiology, epidemiology, diagnosis, and treatment of the major Tick-Borne Diseases that occur in the United States. Biology of Ticks Ticks are obligate blood-sucking members of the . . .

Martin O. Andersson - One of the best experts on this subject based on the ideXlab platform.

  • Canine Tick-Borne Diseases in pet dogs from Romania.
    Parasites & vectors, 2017
    Co-Authors: Martin O. Andersson, Jonas Waldenström, Conny Tolf, Paula Tamba, Mircea Stefanache, Gerhard Dobler, Lidia Chițimia-dobler
    Abstract:

    Background Tick-Borne Diseases are of substantial concern worldwide for animals as well as humans. Dogs have been a human companion for millennia, and their significant impact on human life renders disease in dogs to be of great concern. Tick-Borne Diseases in dogs represent a substantial diagnostic challenge for veterinarians in that clinical signs are often diffuse and overlapping. In addition, co-infections with two or more pathogens enhance this problem further. Molecular methods are useful to disentangle co-infections and to accurately describe prevalence and geographical distribution of Tick-Borne Diseases. At this point, this information is lacking in many areas worldwide. Romania is one such area, where prevalence and distribution of several important pathogens need to be further investigated. To address this, we screened blood samples from 96 sick dogs with molecular methods for eight different pathogens including Babesia spp., Theileria spp., Hepatozoon spp., Anaplasma spp., Ehrlichia spp., “Candidatus Neoehrlichia mikurensis”, Mycoplasma spp., and Borrelia spp.

  • Canine Tick-Borne Diseases in pet dogs from Romania
    Parasites & Vectors, 2017
    Co-Authors: Martin O. Andersson, Jonas Waldenström, Conny Tolf, Paula Tamba, Mircea Stefanache, Gerhard Dobler, Lidia Chițimia-dobler
    Abstract:

    Background Tick-Borne Diseases are of substantial concern worldwide for animals as well as humans. Dogs have been a human companion for millennia, and their significant impact on human life renders disease in dogs to be of great concern. Tick-Borne Diseases in dogs represent a substantial diagnostic challenge for veterinarians in that clinical signs are often diffuse and overlapping. In addition, co-infections with two or more pathogens enhance this problem further. Molecular methods are useful to disentangle co-infections and to accurately describe prevalence and geographical distribution of Tick-Borne Diseases. At this point, this information is lacking in many areas worldwide. Romania is one such area, where prevalence and distribution of several important pathogens need to be further investigated. To address this, we screened blood samples from 96 sick dogs with molecular methods for eight different pathogens including Babesia spp., Theileria spp., Hepatozoon spp., Anaplasma spp., Ehrlichia spp., “ Candidatus Neoehrlichia mikurensis”, Mycoplasma spp., and Borrelia spp. Results As many as 45% (43/96) of the dogs in the study were infected with protozoan parasites. Babesia canis was the most frequent of these (28 infected dogs), whereas Hepatozoon canis was detected in 15% (14/96) and Babesia gibsoni was found in a single sample. Bacterial infection with Mycoplasma spp. occurred in 18% (17/96) of the sampled dogs. Obtained bacterial sequences revealed the occurrence of two species: Mycoplasma canis and “ Candidatus Mycoplasma haematoparvum”. In several cases co-infection with protozoan parasites and Mycoplasma sp. were detected. All dogs were negative for Anaplasma spp., Ehrlichia spp., “ Ca. Neoehrlichia mikurensis”, and for Borrelia spp . Conclusions The results from the present study reinforce the notion that Babesia canis is an important pathogen in the Romanian dog population. However, more surprisingly, another protozoan species, H. canis , seems to be infecting dogs to a larger extent than previously recognized in Romania. Well-known Tick-Borne bacterial disease agents such as Anaplasma spp. and Borrelia spp. were not detected. In contrast, less well-studied bacteria such as hemotropic Mycoplasma spp. were detected frequently. Moreover, co-infection might aggravate disease and complicate diagnosis and should be further studied in dogs.