The Experts below are selected from a list of 14376 Experts worldwide ranked by ideXlab platform
John E Sanderson - One of the best experts on this subject based on the ideXlab platform.
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Tissue Doppler Imaging - A new prognosticator for cardiovascular diseases
Journal of the American College of Cardiology, 2007Co-Authors: John E Sanderson, Thomas H. MarwickAbstract:Tissue Doppler Imaging (TDI) is evolving as a useful echocardiographic tool for quantitative assessment of left ventricular (LV) systolic and diastolic function. Recent studies have explored the prognostic role of TDI-derived parameters in major cardiac diseases, such as heart failure, acute myocardial infarction, and hypertension. In these conditions, myocardial mitral annular or basal segmental (Sm) systolic and early diastolic (Ea or Em) velocities have been shown to predict mortality or cardiovascular events. In particular, those with reduced Sm or Em values of
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Tissue Doppler Imaging provides incremental prognostic value in patients with systemic hypertension and left ventricular hypertrophy
Journal of Hypertension, 2005Co-Authors: Mei Wang, Angela Yeemoon Wang, Pik Yuk Ho, Yan Zhang, Cheukman Yu, John E SandersonAbstract:ObjectivesWe sought to determine the prognostic value of left ventricular (LV) mitral annular velocities measured by Tissue Doppler Imaging (TDI) in hypertensive patients with echocardiographic evidence of LV hypertrophy.BackgroundEcho LV hypertrophy and LV geometry provide additional predictive val
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Tissue Doppler Imaging for predicting outcome in patients with cardiovascular disease.
Current opinion in cardiology, 2004Co-Authors: John E Sanderson, Mei WangAbstract:PURPOSE OF REVIEW: Tissue Doppler Imaging is being increasingly used for assessing global ventricular function in systole and diastole, and for quantifying regional wall motion abnormalities both in systolic heart failure with mechanical dyssynchrony and ischemic heart disease. Its use as a predictive tool is recent and the authors review publications relating to this aspect. RECENT FINDINGS: Peak early diastolic mitral annular velocity is a powerful predictor of outcome in a variety of cardiovascular conditions and adds incremental value to clinical parameters and standard mitral Doppler inflow velocities. Tissue Doppler Imaging can also predict the development of hypertrophic cardiomyopathy in asymptomatic individuals carrying the genetic mutation even before the onset of overt left ventricular hypertrophy. In addition, the standard deviation of the time to peak systolic velocity is a good marker of mechanical asynchrony and can predict reverse remodeling. It may also be useful in identifying individuals with ischemic heart disease and regional wall motion abnormalities who have an adverse outcome. SUMMARY: Tissue Doppler Imaging is a powerful new echocardiographic tool that is now becoming the standard for assessing ventricular function in a variety of situations and diseases.
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peak early diastolic mitral annulus velocity by Tissue Doppler Imaging adds independent and incremental prognostic value
Journal of the American College of Cardiology, 2003Co-Authors: Mei Wang, Angela Yeemoon Wang, Pik Yuk Ho, Yan Zhang, John E SandersonAbstract:Abstract Objectives The aim of this study was to ascertain if left ventricular mitral annulus velocities measured by Tissue Doppler Imaging (TDI) are more powerful predictors of outcome compared with clinical data and standard Doppler-echocardiographic parameters. Background Tissue Doppler Imaging of basal or mitral annulus velocities provides rapid assessment of ventricular long axis function. But it is not known if TDI-derived velocities in systole and diastole add incremental value and are superior to the standard Doppler-echocardiographic measurements as a predictor of outcome. Methods The study population consisted of 518 subjects, 353 with cardiac disease and 165 normal subjects who had full Doppler two-dimensional–echocardiographic studies with measurement of mitral inflow velocities in early and late diastole, E-wave deceleration time (DT), peak systolic mitral annular velocity (Sm) early and late diastolic mitral annular velocity (Em and Am) by TDI, early diastolic flow propagation velocity, and standard chamber dimensions. All subjects were followed up for two years. The end point was cardiac death. Results Tissue Doppler Imaging mitral annulus systolic and diastolic velocities were all significantly lower in the non-survivors (all p Conclusions Mitral annulus velocity measured by TDI in early diastole gives incremental predictive power for cardiac mortality compared to clinical data and standard echocardiographic measurements. This easily available measurement adds significant value in the clinical management of cardiac patients.
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peak early diastolic mitral annulus velocity by Tissue Doppler Imaging adds independent and incremental prognostic value
Journal of the American College of Cardiology, 2003Co-Authors: Mei Wang, Angela Yeemoon Wang, Yan Zhang, Gabriel W K Yip, Mui Kiu Tse, Peggo K W Lam, John E SandersonAbstract:OBJECTIVES The aim of this study was to ascertain if left ventricular mitral annulus velocities measured by Tissue Doppler Imaging (TDI) are more powerful predictors of outcome compared with clinical data and standard Doppler-echocardiographic parameters. BACKGROUND Tissue Doppler Imaging of basal or mitral annulus velocities provides rapid assessment of ventricular long axis function. But it is not known if TDI-derived velocities in systole and diastole add incremental value and are superior to the standard Doppler-echocardiographic measurements as a predictor of outcome. METHODS The study population consisted of 518 subjects, 353 with cardiac disease and 165 normal subjects who had full Doppler two-dimensional-echocardiographic studies with measurement of mitral inflow velocities in early and late diastole, E-wave deceleration time (DT), peak systolic mitral annular velocity (Sm) early and late diastolic mitral annular velocity (Em and Am) by TDI, early diastolic flow propagation velocity, and standard chamber dimensions. All subjects were followed up for two years. The end point was cardiac death. RESULTS Tissue Doppler Imaging mitral annulus systolic and diastolic velocities were all significantly lower in the non-survivors (all p < 0.05) as was DT (p = 0.024). In the Cox model the best predictors of mortality were Em, Sm, Am, left ventricular ejection fraction, left ventricular mass, and left atrial diameter in systole (LADs). By backward stepwise analysis Em and LADs were the strongest predictors. After forcing the TDI measurements into the covariate model with clinical and mitral DT <0.16 s, Em provided significant incremental value for predicting cardiac mortality (p = 0.004). CONCLUSIONS Mitral annulus velocity measured by TDI in early diastole gives incremental predictive power for cardiac mortality compared to clinical data and standard echocardiographic measurements. This easily available measurement adds significant value in the clinical management of cardiac patients.
Mei Wang - One of the best experts on this subject based on the ideXlab platform.
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Tissue Doppler Imaging provides incremental prognostic value in patients with systemic hypertension and left ventricular hypertrophy
Journal of Hypertension, 2005Co-Authors: Mei Wang, Angela Yeemoon Wang, Pik Yuk Ho, Yan Zhang, Cheukman Yu, John E SandersonAbstract:ObjectivesWe sought to determine the prognostic value of left ventricular (LV) mitral annular velocities measured by Tissue Doppler Imaging (TDI) in hypertensive patients with echocardiographic evidence of LV hypertrophy.BackgroundEcho LV hypertrophy and LV geometry provide additional predictive val
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Tissue Doppler Imaging for predicting outcome in patients with cardiovascular disease.
Current opinion in cardiology, 2004Co-Authors: John E Sanderson, Mei WangAbstract:PURPOSE OF REVIEW: Tissue Doppler Imaging is being increasingly used for assessing global ventricular function in systole and diastole, and for quantifying regional wall motion abnormalities both in systolic heart failure with mechanical dyssynchrony and ischemic heart disease. Its use as a predictive tool is recent and the authors review publications relating to this aspect. RECENT FINDINGS: Peak early diastolic mitral annular velocity is a powerful predictor of outcome in a variety of cardiovascular conditions and adds incremental value to clinical parameters and standard mitral Doppler inflow velocities. Tissue Doppler Imaging can also predict the development of hypertrophic cardiomyopathy in asymptomatic individuals carrying the genetic mutation even before the onset of overt left ventricular hypertrophy. In addition, the standard deviation of the time to peak systolic velocity is a good marker of mechanical asynchrony and can predict reverse remodeling. It may also be useful in identifying individuals with ischemic heart disease and regional wall motion abnormalities who have an adverse outcome. SUMMARY: Tissue Doppler Imaging is a powerful new echocardiographic tool that is now becoming the standard for assessing ventricular function in a variety of situations and diseases.
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peak early diastolic mitral annulus velocity by Tissue Doppler Imaging adds independent and incremental prognostic value
Journal of the American College of Cardiology, 2003Co-Authors: Mei Wang, Angela Yeemoon Wang, Pik Yuk Ho, Yan Zhang, John E SandersonAbstract:Abstract Objectives The aim of this study was to ascertain if left ventricular mitral annulus velocities measured by Tissue Doppler Imaging (TDI) are more powerful predictors of outcome compared with clinical data and standard Doppler-echocardiographic parameters. Background Tissue Doppler Imaging of basal or mitral annulus velocities provides rapid assessment of ventricular long axis function. But it is not known if TDI-derived velocities in systole and diastole add incremental value and are superior to the standard Doppler-echocardiographic measurements as a predictor of outcome. Methods The study population consisted of 518 subjects, 353 with cardiac disease and 165 normal subjects who had full Doppler two-dimensional–echocardiographic studies with measurement of mitral inflow velocities in early and late diastole, E-wave deceleration time (DT), peak systolic mitral annular velocity (Sm) early and late diastolic mitral annular velocity (Em and Am) by TDI, early diastolic flow propagation velocity, and standard chamber dimensions. All subjects were followed up for two years. The end point was cardiac death. Results Tissue Doppler Imaging mitral annulus systolic and diastolic velocities were all significantly lower in the non-survivors (all p Conclusions Mitral annulus velocity measured by TDI in early diastole gives incremental predictive power for cardiac mortality compared to clinical data and standard echocardiographic measurements. This easily available measurement adds significant value in the clinical management of cardiac patients.
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peak early diastolic mitral annulus velocity by Tissue Doppler Imaging adds independent and incremental prognostic value
Journal of the American College of Cardiology, 2003Co-Authors: Mei Wang, Angela Yeemoon Wang, Yan Zhang, Gabriel W K Yip, Mui Kiu Tse, Peggo K W Lam, John E SandersonAbstract:OBJECTIVES The aim of this study was to ascertain if left ventricular mitral annulus velocities measured by Tissue Doppler Imaging (TDI) are more powerful predictors of outcome compared with clinical data and standard Doppler-echocardiographic parameters. BACKGROUND Tissue Doppler Imaging of basal or mitral annulus velocities provides rapid assessment of ventricular long axis function. But it is not known if TDI-derived velocities in systole and diastole add incremental value and are superior to the standard Doppler-echocardiographic measurements as a predictor of outcome. METHODS The study population consisted of 518 subjects, 353 with cardiac disease and 165 normal subjects who had full Doppler two-dimensional-echocardiographic studies with measurement of mitral inflow velocities in early and late diastole, E-wave deceleration time (DT), peak systolic mitral annular velocity (Sm) early and late diastolic mitral annular velocity (Em and Am) by TDI, early diastolic flow propagation velocity, and standard chamber dimensions. All subjects were followed up for two years. The end point was cardiac death. RESULTS Tissue Doppler Imaging mitral annulus systolic and diastolic velocities were all significantly lower in the non-survivors (all p < 0.05) as was DT (p = 0.024). In the Cox model the best predictors of mortality were Em, Sm, Am, left ventricular ejection fraction, left ventricular mass, and left atrial diameter in systole (LADs). By backward stepwise analysis Em and LADs were the strongest predictors. After forcing the TDI measurements into the covariate model with clinical and mitral DT <0.16 s, Em provided significant incremental value for predicting cardiac mortality (p = 0.004). CONCLUSIONS Mitral annulus velocity measured by TDI in early diastole gives incremental predictive power for cardiac mortality compared to clinical data and standard echocardiographic measurements. This easily available measurement adds significant value in the clinical management of cardiac patients.
Jos R.t.c. Roelandt - One of the best experts on this subject based on the ideXlab platform.
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Technological advances in Tissue Doppler Imaging echocardiography
Heart, 2008Co-Authors: N. Van De Veire, J. De Sutter, Jos R.t.c. RoelandtAbstract:Tissue Doppler Imaging is a recently introduced echocardiographic tool for measuring myocardial velocities. In this article the physical principles and different myocardial velocity Imaging modalities are discussed. Examples of practical applications and clinical use of this non-invasive Imaging technique are provided.
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Technological advances in Tissue Doppler Imaging echocardiography
Heart, 2008Co-Authors: N. Van De Veire, J. De Sutter, Jos R.t.c. RoelandtAbstract:Tissue Doppler Imaging is a recently introduced echocardiographic tool for measuring myocardial velocities. In this article the physical principles and different myocardial velocity Imaging modalities are discussed. Examples of practical applications and clinical use of this non-invasive Imaging technique are provided.
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Pulsed wave Tissue Doppler Imaging for the quantification of contractile reserve in stunned, hibernating, and scarred myocardium.
Heart (British Cardiac Society), 2004Co-Authors: M. Bountioukos, Jos R.t.c. Roelandt, Arend F.l. Schinkel, J.j. Bax, Vittoria Rizzello, Roelf Valkema, Boudewijn J. Krenning, Elena Biagini, Eleni C. Vourvouri, D PoldermansAbstract:Objectives: To assess whether quantification of myocardial systolic velocities by pulsed wave Tissue Doppler Imaging can differentiate between stunned, hibernating, and scarred myocardium. Design: Observational study. Setting: Tertiary referral centre. Patients: 70 patients with reduced left ventricular function caused by chronic coronary artery disease. Methods: Pulsed wave Tissue Doppler Imaging was done close to the mitral annulus at rest and during low dose dobutamine; systolic ejection velocity (Vs) and the difference in Vs between low dose dobutamine and the resting value (ΔVs) were assessed using a six segment model. Assessment of perfusion (with Tc-99m-tetrofosmin SPECT) and glucose utilisation (by 18 F-fluorodeoxyglucose SPECT) was used to classify dysfunctional regions (by resting cross sectional echocardiography) as stunned, hibernating, or scarred. Results: 253 of 420 regions (60%) were dysfunctional. Of these, 132 (52%) were classified as stunned, 25 (10%) as hibernating, and 96 (38%) as scarred. At rest, Vs in stunned, hibernating, and scar Tissue was, respectively, 6.3 (1.8), 6.6 (2.2), and 5.5 (1.5) cm/s (p = 0.001 by ANOVA). There was a gradual decline in Vs during low dose dobutamine infusion between stunned, hibernating, and scar Tissue (8.3 (2.6) v 7.8 (1.5) v 6.8 (1.9) cm/s, p Conclusions: Quantitative Tissue Doppler Imaging showed a gradual reduction in regional velocities between stunned, hibernating, and scarred myocardium. Dobutamine induced contractile reserve was higher in stunned regions than in hibernating and scarred myocardium, reflecting different severities of myocardial damage.
Thomas H. Marwick - One of the best experts on this subject based on the ideXlab platform.
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Tissue Doppler Imaging - A new prognosticator for cardiovascular diseases
Journal of the American College of Cardiology, 2007Co-Authors: John E Sanderson, Thomas H. MarwickAbstract:Tissue Doppler Imaging (TDI) is evolving as a useful echocardiographic tool for quantitative assessment of left ventricular (LV) systolic and diastolic function. Recent studies have explored the prognostic role of TDI-derived parameters in major cardiac diseases, such as heart failure, acute myocardial infarction, and hypertension. In these conditions, myocardial mitral annular or basal segmental (Sm) systolic and early diastolic (Ea or Em) velocities have been shown to predict mortality or cardiovascular events. In particular, those with reduced Sm or Em values of
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Tissue Doppler Imaging for evaluation of myocardial function in patients with diabetes mellitus.
Current opinion in cardiology, 2004Co-Authors: Thomas H. MarwickAbstract:Purpose of review Heart failure and diabetes mellitus are frequently associated, and diabetes appears to potentiate the clinical presentation of heart failure related to other causes. The purpose of this review is to examine recent advances in the application of Tissue Doppler Imaging for the assessment of diabetic heart disease. Recent findings Recent studies have documented that both myocardial systolic and diastolic abnormalities can be identified in apparently healthy patients with diabetes and no overt cardiac dysfunction. Interestingly, these are disturbances of longitudinal function, with compensatory increases of radial function-suggesting primary involvement of the subendocardium, which is a hallmark of myocardial ischemia. Despite this, there is limited evidence that diabetic microangiopathy is responsible-with reduced myocardial blood volume rather than reduced resting flow, and at least some evidence suggesting a normal increment of Tissue velocity with stress. Finally, a few correlative studies have shown association of diabetic myocardial disease with poor glycemic control, while angiotensin converting enzyme inhibition may be protective. Summary Tissue Doppler Imaging (and the related technique of strain rate Imaging) appears to be extremely effective for the identification of subclinical LV dysfunction in diabetic patients It is hoped that the recognition of this condition will prompt specific therapy to prevent the development of overt LV dysfunction.
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Clinical applications of Tissue Doppler Imaging: a promise fulfilled.
Heart (British Cardiac Society), 2003Co-Authors: Thomas H. MarwickAbstract:The clinical applications of Tissue Doppler Imaging in the assessment of left ventricular diastolic function have moved from the experimental lab to clinical practice
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Evaluation of resynchronization of contractile function following biventricular pacing using colour Tissue Doppler Imaging
Journal of the American College of Cardiology, 2002Co-Authors: Jeroen J. Bax, Thomas H. Marwick, L. Van Erven, Sander G. Molhoek, C. Adriaansche, R. De Melker, Paul J. Voogd, E. E. Van Der Wall, Martin J SchalijAbstract:Biventdcular (BV) pacing is evaluated as an alternative treatment for patients with dilated cardiomyppathy (both ischemic and non-ischemic) and end-stage heart failure. Colour Tissue Doppler Imaging using echocardiography allows noninvasive, quantitative assessment of radial motion in the long-axis with measurement of peak systolic velocity timing. The aim of the present study was to evaluate quantitatively, the systolic performance of the left ventricle and the resynchrenization of contraction (before vs after implantation). Patients and methods: 25 patients with dilated cardiomyopathy (11 ischemic), NYHA class III or IV, QRS duration >120 ms received a biventricular pacemaker. Routine 2D echo and colour Tissue Doppler Imaging were performed before and within 1 week following implantation. LVEF was assessed using the biplane Sampson's method.Peak systolic velocity (PSV) and time to PSV (TPV) were assessed in 4 regions (basal anterior, inferior, lateral and septal). By averaging the TPV from all 4 regions, a synchronization index was dedved from these measurements. Reaults: LVEF improved by 9±9% following pacing; 17 patients improved LVEF 5% or more. The change in PSV in the septal and lateral regions related significantly to the change in LVEF (r=0.74, r=0.62).The change in synchronization index before vs after pacing (as a measurement of REsynchronization) was related to the change in LVEF (y=120x+5.6, r=0.79, P
Nese Cam - One of the best experts on this subject based on the ideXlab platform.
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Occult cardiac dysfunction in patients with obstructive sleep apnea syndrome revealed by Tissue Doppler Imaging
International journal of cardiology, 2006Co-Authors: Hulya Kasikcioglu, Levent Karasulu, Zeynep Tartan, Erdem Kasikcioglu, Caglar Cuhadaroglu, Nese CamAbstract:Obstructive sleep apnea syndrome has been linked to cardiovascular complications. The diagnosis of effects of sleep apnea on heart may be difficult before apparent examination findings. The aim of the present study was to evaluate changes of myocardial contractile properties in patients affected by sleep apnea showing Tissue Doppler Imaging, in the face of quite normal myocardial contractility on standard echocardiography. Shortly, Tissue Doppler Imaging may represent an early stage of myocardial abnormality despite a preserved global function.
