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Andrew Carr - One of the best experts on this subject based on the ideXlab platform.
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In vivo measurement of Tissue Metabolism in tendons of the rotator cuff - Reply
The Journal of bone and joint surgery. British volume, 2008Co-Authors: Matthews Tjw., Andrew CarrAbstract:We have undertaken an in vivo assessment of the Tissue Metabolism and cellular activity in torn tendons of the rotator cuff. Cellular oxygen consumption was measured in 13 patients undergoing mini-open repair of small, medium, large and massive full-thickness tears. Measurements were also taken from three control patients who were undergoing open stabilisation of the shoulder with grossly normal tendons. The level of oxygen and nitrous oxide was measured amperometrically using silver needle microelectrodes at the apex of the tear and 1.5 cm from its edge. With nitrous oxide indicating the degree of perfusion, oxygen consumption was calculated at each location to reflect cellular activity. All of the torn tendons had lower levels of cellular activity than the control group. This activity was lower still in the Tissue nearest to the edge of the tear with the larger tears showing the lowest activity. This indicated reduced levels of Tissue Metabolism and infers a reduction in tendon viability. Our findings suggest that surgical repair of torn tendons of the rotator-cuff should include the more proximal, viable Tissue, and may help to explain the high rate of re-rupture seen in larger tears.
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In vivo measurement of Tissue Metabolism in tendons of the rotator cuff: implications for surgical management.
The Journal of bone and joint surgery. British volume, 2007Co-Authors: T. Matthews, S R Smith, Jill P. G. Urban, J. L. Rees, Chris Peach, Andrew CarrAbstract:We have undertaken an in vivo assessment of the Tissue Metabolism and cellular activity in torn tendons of the rotator cuff. Cellular oxygen consumption was measured in 13 patients undergoing mini-open repair of small, medium, large and massive full-thickness tears. Measurements were also taken from three control patients who were undergoing open stabilisation of the shoulder with grossly normal tendons. The level of oxygen and nitrous oxide was measured amperometrically using silver needle microelectrodes at the apex of the tear and 1.5 cm from its edge. With nitrous oxide indicating the degree of perfusion, oxygen consumption was calculated at each location to reflect cellular activity. All of the torn tendons had lower levels of cellular activity than the control group. This activity was lower still in the Tissue nearest to the edge of the tear with the larger tears showing the lowest activity. This indicated reduced levels of Tissue Metabolism and infers a reduction in tendon viability. Our findings suggest that surgical repair of torn tendons of the rotator-cuff should include the more proximal, viable Tissue, and may help to explain the high rate of re-rupture seen in larger tears.
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IN VIVO MEASUREMENT OF Tissue Metabolism IN ROTATOR CUFF TENDONS: IMPLICATIONS FOR SURGICAL MANAGEMENT
Journal of Bone and Joint Surgery-british Volume, 2005Co-Authors: T.j.w. Matthews, S R Smith, Jill P. G. Urban, Andrew CarrAbstract:Aim To determine if Tissue Metabolism varies in supraspinatus tendons with distance from the edge of the rotator cuff tendon tear and also with differing size of tear. Background Tissue Metabolism can be assessed by measuring oxygen and nitrous oxide concentrations within the Tissue. Viable tendon Tissue consumes oxygen and contains nitrous oxide (used in the general anaesthetic) from the blood stream. Non-viable tendon Tissue will not consume oxygen but will contain nitrous oxide. Methods Oxygen and Nitrous Oxide concentrations were measured amperometrically using silver needle microelectrodes. The needle was inserted into the supraspinatus tendon of patients with massive, large, medium and small full thickness rotator cuff tears and patients with partial thickness and no tears. Patients undergoing open stabilisation were used as controls. Measurements were made at a number of quantifiable points from the tendon edge to allow the creation of a topographical map of Tissue Metabolism. Oxygen consumption was calculated using measured oxygen and nitrous oxide levels at each point. Results In patients with rotator cuff tears oxygen consumption was significantly lower near to the edge of the tear. Patients with impingement syndrome but no evidence of a rotator cuff tear also showed a decreased level of oxygen consumption in the anterior part of supraspinatus, but this was significantly higher than the levels seen in the torn tendon. The control group showed no significant alteration in oxygen levels Conclusion Patients with rotator cuff tendon tear demonstrate significantly reduced levels of Tissue Metabolism. This reduction in Tissue viability is significantly greater at the edge of the tear and in larger tears. Patients with intact tendons and impingement syndrome also demonstrate minor reduction in Tissue tendon viability compared with controls.
S R Smith - One of the best experts on this subject based on the ideXlab platform.
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IN VIVO MEASUREMENT OF Tissue Metabolism IN ROTATOR CUFF TENDONS: IMPLICATIONS FOR SURGICAL MANAGEMENT
2018Co-Authors: Matthews T.j.w., S R Smith, Urban J.p.g., A J CarrAbstract:Aim To determine if Tissue Metabolism varies in supraspinatus tendons with distance from the edge of the rotator cuff tendon tear and also with differing size of tear.Background Tissue Metabolism can be assessed by measuring oxygen and nitrous oxide concentrations within the Tissue. Viable tendon Tissue consumes oxygen and contains nitrous oxide (used in the general anaesthetic) from the blood stream. Non-viable tendon Tissue will not consume oxygen but will contain nitrous oxide.Methods Oxygen and Nitrous Oxide concentrations were measured amperometrically using silver needle microelectrodes.The needle was inserted into the supraspinatus tendon of patients with massive, large, medium and small full thickness rotator cuff tears and patients with partial thickness and no tears. Patients undergoing open stabilisation were used as controls. Measurements were made at a number of quantifiable points from the tendon edge to allow the creation of a topographical map of Tissue Metabolism. Oxygen consumption was c...
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In vivo measurement of Tissue Metabolism in tendons of the rotator cuff
The Journal of Bone and Joint Surgery. British volume, 2007Co-Authors: T.j.w. Matthews, S R Smith, Jill P. G. Urban, C. A. Peach, J. L. Rees, A J CarrAbstract:We have undertaken an in vivo assessment of the Tissue Metabolism and cellular activity in torn tendons of the rotator cuff. Cellular oxygen consumption was measured in 13 patients undergoing mini-open repair of small, medium, large and massive full-thickness tears. Measurements were also taken from three control patients who were undergoing open stabilisation of the shoulder with grossly normal tendons. The level of oxygen and nitrous oxide was measured amperometrically using silver needle microelectrodes at the apex of the tear and 1.5 cm from its edge. With nitrous oxide indicating the degree of perfusion, oxygen consumption was calculated at each location to reflect cellular activity. All of the torn tendons had lower levels of cellular activity than the control group. This activity was lower still in the Tissue nearest to the edge of the tear with the larger tears showing the lowest activity. This indicated reduced levels of Tissue Metabolism and infers a reduction in tendon viability. Our findings suggest that surgical repair of torn tendons of the rotator-cuff should include the more proximal, viable Tissue, and may help to explain the high rate of re-rupture seen in larger tears
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In vivo measurement of Tissue Metabolism in tendons of the rotator cuff: implications for surgical management.
The Journal of bone and joint surgery. British volume, 2007Co-Authors: T. Matthews, S R Smith, Jill P. G. Urban, J. L. Rees, Chris Peach, Andrew CarrAbstract:We have undertaken an in vivo assessment of the Tissue Metabolism and cellular activity in torn tendons of the rotator cuff. Cellular oxygen consumption was measured in 13 patients undergoing mini-open repair of small, medium, large and massive full-thickness tears. Measurements were also taken from three control patients who were undergoing open stabilisation of the shoulder with grossly normal tendons. The level of oxygen and nitrous oxide was measured amperometrically using silver needle microelectrodes at the apex of the tear and 1.5 cm from its edge. With nitrous oxide indicating the degree of perfusion, oxygen consumption was calculated at each location to reflect cellular activity. All of the torn tendons had lower levels of cellular activity than the control group. This activity was lower still in the Tissue nearest to the edge of the tear with the larger tears showing the lowest activity. This indicated reduced levels of Tissue Metabolism and infers a reduction in tendon viability. Our findings suggest that surgical repair of torn tendons of the rotator-cuff should include the more proximal, viable Tissue, and may help to explain the high rate of re-rupture seen in larger tears.
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IN VIVO MEASUREMENT OF Tissue Metabolism IN ROTATOR CUFF TENDONS: IMPLICATIONS FOR SURGICAL MANAGEMENT
Journal of Bone and Joint Surgery-british Volume, 2005Co-Authors: T.j.w. Matthews, S R Smith, Jill P. G. Urban, Andrew CarrAbstract:Aim To determine if Tissue Metabolism varies in supraspinatus tendons with distance from the edge of the rotator cuff tendon tear and also with differing size of tear. Background Tissue Metabolism can be assessed by measuring oxygen and nitrous oxide concentrations within the Tissue. Viable tendon Tissue consumes oxygen and contains nitrous oxide (used in the general anaesthetic) from the blood stream. Non-viable tendon Tissue will not consume oxygen but will contain nitrous oxide. Methods Oxygen and Nitrous Oxide concentrations were measured amperometrically using silver needle microelectrodes. The needle was inserted into the supraspinatus tendon of patients with massive, large, medium and small full thickness rotator cuff tears and patients with partial thickness and no tears. Patients undergoing open stabilisation were used as controls. Measurements were made at a number of quantifiable points from the tendon edge to allow the creation of a topographical map of Tissue Metabolism. Oxygen consumption was calculated using measured oxygen and nitrous oxide levels at each point. Results In patients with rotator cuff tears oxygen consumption was significantly lower near to the edge of the tear. Patients with impingement syndrome but no evidence of a rotator cuff tear also showed a decreased level of oxygen consumption in the anterior part of supraspinatus, but this was significantly higher than the levels seen in the torn tendon. The control group showed no significant alteration in oxygen levels Conclusion Patients with rotator cuff tendon tear demonstrate significantly reduced levels of Tissue Metabolism. This reduction in Tissue viability is significantly greater at the edge of the tear and in larger tears. Patients with intact tendons and impingement syndrome also demonstrate minor reduction in Tissue tendon viability compared with controls.
Jill P. G. Urban - One of the best experts on this subject based on the ideXlab platform.
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In vivo measurement of Tissue Metabolism in tendons of the rotator cuff: implications for surgical management.
The Journal of bone and joint surgery. British volume, 2007Co-Authors: T. Matthews, S R Smith, Jill P. G. Urban, J. L. Rees, Chris Peach, Andrew CarrAbstract:We have undertaken an in vivo assessment of the Tissue Metabolism and cellular activity in torn tendons of the rotator cuff. Cellular oxygen consumption was measured in 13 patients undergoing mini-open repair of small, medium, large and massive full-thickness tears. Measurements were also taken from three control patients who were undergoing open stabilisation of the shoulder with grossly normal tendons. The level of oxygen and nitrous oxide was measured amperometrically using silver needle microelectrodes at the apex of the tear and 1.5 cm from its edge. With nitrous oxide indicating the degree of perfusion, oxygen consumption was calculated at each location to reflect cellular activity. All of the torn tendons had lower levels of cellular activity than the control group. This activity was lower still in the Tissue nearest to the edge of the tear with the larger tears showing the lowest activity. This indicated reduced levels of Tissue Metabolism and infers a reduction in tendon viability. Our findings suggest that surgical repair of torn tendons of the rotator-cuff should include the more proximal, viable Tissue, and may help to explain the high rate of re-rupture seen in larger tears.
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In vivo measurement of Tissue Metabolism in tendons of the rotator cuff
The Journal of Bone and Joint Surgery. British volume, 2007Co-Authors: T.j.w. Matthews, S R Smith, Jill P. G. Urban, C. A. Peach, J. L. Rees, A J CarrAbstract:We have undertaken an in vivo assessment of the Tissue Metabolism and cellular activity in torn tendons of the rotator cuff. Cellular oxygen consumption was measured in 13 patients undergoing mini-open repair of small, medium, large and massive full-thickness tears. Measurements were also taken from three control patients who were undergoing open stabilisation of the shoulder with grossly normal tendons. The level of oxygen and nitrous oxide was measured amperometrically using silver needle microelectrodes at the apex of the tear and 1.5 cm from its edge. With nitrous oxide indicating the degree of perfusion, oxygen consumption was calculated at each location to reflect cellular activity. All of the torn tendons had lower levels of cellular activity than the control group. This activity was lower still in the Tissue nearest to the edge of the tear with the larger tears showing the lowest activity. This indicated reduced levels of Tissue Metabolism and infers a reduction in tendon viability. Our findings suggest that surgical repair of torn tendons of the rotator-cuff should include the more proximal, viable Tissue, and may help to explain the high rate of re-rupture seen in larger tears
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IN VIVO MEASUREMENT OF Tissue Metabolism IN ROTATOR CUFF TENDONS: IMPLICATIONS FOR SURGICAL MANAGEMENT
Journal of Bone and Joint Surgery-british Volume, 2005Co-Authors: T.j.w. Matthews, S R Smith, Jill P. G. Urban, Andrew CarrAbstract:Aim To determine if Tissue Metabolism varies in supraspinatus tendons with distance from the edge of the rotator cuff tendon tear and also with differing size of tear. Background Tissue Metabolism can be assessed by measuring oxygen and nitrous oxide concentrations within the Tissue. Viable tendon Tissue consumes oxygen and contains nitrous oxide (used in the general anaesthetic) from the blood stream. Non-viable tendon Tissue will not consume oxygen but will contain nitrous oxide. Methods Oxygen and Nitrous Oxide concentrations were measured amperometrically using silver needle microelectrodes. The needle was inserted into the supraspinatus tendon of patients with massive, large, medium and small full thickness rotator cuff tears and patients with partial thickness and no tears. Patients undergoing open stabilisation were used as controls. Measurements were made at a number of quantifiable points from the tendon edge to allow the creation of a topographical map of Tissue Metabolism. Oxygen consumption was calculated using measured oxygen and nitrous oxide levels at each point. Results In patients with rotator cuff tears oxygen consumption was significantly lower near to the edge of the tear. Patients with impingement syndrome but no evidence of a rotator cuff tear also showed a decreased level of oxygen consumption in the anterior part of supraspinatus, but this was significantly higher than the levels seen in the torn tendon. The control group showed no significant alteration in oxygen levels Conclusion Patients with rotator cuff tendon tear demonstrate significantly reduced levels of Tissue Metabolism. This reduction in Tissue viability is significantly greater at the edge of the tear and in larger tears. Patients with intact tendons and impingement syndrome also demonstrate minor reduction in Tissue tendon viability compared with controls.
T.j.w. Matthews - One of the best experts on this subject based on the ideXlab platform.
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In vivo measurement of Tissue Metabolism in tendons of the rotator cuff
The Journal of Bone and Joint Surgery. British volume, 2007Co-Authors: T.j.w. Matthews, S R Smith, Jill P. G. Urban, C. A. Peach, J. L. Rees, A J CarrAbstract:We have undertaken an in vivo assessment of the Tissue Metabolism and cellular activity in torn tendons of the rotator cuff. Cellular oxygen consumption was measured in 13 patients undergoing mini-open repair of small, medium, large and massive full-thickness tears. Measurements were also taken from three control patients who were undergoing open stabilisation of the shoulder with grossly normal tendons. The level of oxygen and nitrous oxide was measured amperometrically using silver needle microelectrodes at the apex of the tear and 1.5 cm from its edge. With nitrous oxide indicating the degree of perfusion, oxygen consumption was calculated at each location to reflect cellular activity. All of the torn tendons had lower levels of cellular activity than the control group. This activity was lower still in the Tissue nearest to the edge of the tear with the larger tears showing the lowest activity. This indicated reduced levels of Tissue Metabolism and infers a reduction in tendon viability. Our findings suggest that surgical repair of torn tendons of the rotator-cuff should include the more proximal, viable Tissue, and may help to explain the high rate of re-rupture seen in larger tears
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IN VIVO MEASUREMENT OF Tissue Metabolism IN ROTATOR CUFF TENDONS: IMPLICATIONS FOR SURGICAL MANAGEMENT
Journal of Bone and Joint Surgery-british Volume, 2005Co-Authors: T.j.w. Matthews, S R Smith, Jill P. G. Urban, Andrew CarrAbstract:Aim To determine if Tissue Metabolism varies in supraspinatus tendons with distance from the edge of the rotator cuff tendon tear and also with differing size of tear. Background Tissue Metabolism can be assessed by measuring oxygen and nitrous oxide concentrations within the Tissue. Viable tendon Tissue consumes oxygen and contains nitrous oxide (used in the general anaesthetic) from the blood stream. Non-viable tendon Tissue will not consume oxygen but will contain nitrous oxide. Methods Oxygen and Nitrous Oxide concentrations were measured amperometrically using silver needle microelectrodes. The needle was inserted into the supraspinatus tendon of patients with massive, large, medium and small full thickness rotator cuff tears and patients with partial thickness and no tears. Patients undergoing open stabilisation were used as controls. Measurements were made at a number of quantifiable points from the tendon edge to allow the creation of a topographical map of Tissue Metabolism. Oxygen consumption was calculated using measured oxygen and nitrous oxide levels at each point. Results In patients with rotator cuff tears oxygen consumption was significantly lower near to the edge of the tear. Patients with impingement syndrome but no evidence of a rotator cuff tear also showed a decreased level of oxygen consumption in the anterior part of supraspinatus, but this was significantly higher than the levels seen in the torn tendon. The control group showed no significant alteration in oxygen levels Conclusion Patients with rotator cuff tendon tear demonstrate significantly reduced levels of Tissue Metabolism. This reduction in Tissue viability is significantly greater at the edge of the tear and in larger tears. Patients with intact tendons and impingement syndrome also demonstrate minor reduction in Tissue tendon viability compared with controls.
A J Carr - One of the best experts on this subject based on the ideXlab platform.
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IN VIVO MEASUREMENT OF Tissue Metabolism IN ROTATOR CUFF TENDONS: IMPLICATIONS FOR SURGICAL MANAGEMENT
2018Co-Authors: Matthews T.j.w., S R Smith, Urban J.p.g., A J CarrAbstract:Aim To determine if Tissue Metabolism varies in supraspinatus tendons with distance from the edge of the rotator cuff tendon tear and also with differing size of tear.Background Tissue Metabolism can be assessed by measuring oxygen and nitrous oxide concentrations within the Tissue. Viable tendon Tissue consumes oxygen and contains nitrous oxide (used in the general anaesthetic) from the blood stream. Non-viable tendon Tissue will not consume oxygen but will contain nitrous oxide.Methods Oxygen and Nitrous Oxide concentrations were measured amperometrically using silver needle microelectrodes.The needle was inserted into the supraspinatus tendon of patients with massive, large, medium and small full thickness rotator cuff tears and patients with partial thickness and no tears. Patients undergoing open stabilisation were used as controls. Measurements were made at a number of quantifiable points from the tendon edge to allow the creation of a topographical map of Tissue Metabolism. Oxygen consumption was c...
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In vivo measurement of Tissue Metabolism in tendons of the rotator cuff
The Journal of Bone and Joint Surgery. British volume, 2007Co-Authors: T.j.w. Matthews, S R Smith, Jill P. G. Urban, C. A. Peach, J. L. Rees, A J CarrAbstract:We have undertaken an in vivo assessment of the Tissue Metabolism and cellular activity in torn tendons of the rotator cuff. Cellular oxygen consumption was measured in 13 patients undergoing mini-open repair of small, medium, large and massive full-thickness tears. Measurements were also taken from three control patients who were undergoing open stabilisation of the shoulder with grossly normal tendons. The level of oxygen and nitrous oxide was measured amperometrically using silver needle microelectrodes at the apex of the tear and 1.5 cm from its edge. With nitrous oxide indicating the degree of perfusion, oxygen consumption was calculated at each location to reflect cellular activity. All of the torn tendons had lower levels of cellular activity than the control group. This activity was lower still in the Tissue nearest to the edge of the tear with the larger tears showing the lowest activity. This indicated reduced levels of Tissue Metabolism and infers a reduction in tendon viability. Our findings suggest that surgical repair of torn tendons of the rotator-cuff should include the more proximal, viable Tissue, and may help to explain the high rate of re-rupture seen in larger tears
