The Experts below are selected from a list of 35733 Experts worldwide ranked by ideXlab platform
Peter A Willis - One of the best experts on this subject based on the ideXlab platform.
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identification of primary amines in Titan tholins using microchip nonaqueous capillary electrophoresis
Earth and Planetary Science Letters, 2014Co-Authors: Morgan L Cable, Amanda M Stockton, Maria F Mora, Sarah M Horst, Mark A Smith, Margaret A Tolbert, Peter A WillisAbstract:Abstract Titan, the moon of Saturn with a thick atmosphere and an active hydrocarbon-based weather cycle, is considered the best target in the solar system for the study of organic chemistry on a planetary scale. Microfluidic devices that employ liquid phase techniques such as capillary electrophoresis with ultrasensitive laser-induced fluorescence detection offer a unique solution for in situ analysis of complex organics on Titan. We previously reported a protocol for nonaqueous microfluidic analysis of primary aliphatic amines in ethanol, and demonstrated separations of short- and long-chain amines down to −20 °C. We have optimized this protocol further, and used it to analyze Titan aerosol analogues (tholins) generated in two separate laboratories under a variety of different conditions. Ethylamine was a major product in all samples, though significant differences in amine content were observed, in particular for long-chain amines (C12–C27). This work validates microfluidic chemical analysis of complex organics with relevance to Titan, and represents a significant first step in understanding tholin composition via targeted functional group analysis.
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low temperature microchip nonaqueous capillary electrophoresis of aliphatic primary amines applications to Titan chemistry
Analytical Chemistry, 2013Co-Authors: Morgan L Cable, Amanda M Stockton, Maria F Mora, Peter A WillisAbstract:We demonstrate microchip nonaqueous capillary electrophoresis (μNACE) analysis of primary aliphatic amines (C1–C18) in ethanol down to −20 °C as a first step in adapting microfluidic protocols for in situ analysis on Titan. To our knowledge, this is the first report of a nonaqueous separation at −20 °C on-chip. Limits of detection (LODs) ranged from 1.0 nM to 2.6 nM, and we identified several primary amines ranging in length from C2 to C16 in Titan aerosol analogue (tholin) samples; new amines were also detected in a tholin sample exposed to oxygen and liquid water. This preliminary work validates the sensitivity and efficacy of microfluidic chemical analysis of complex organics with relevance to Titan aerosols and surface deposits.
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Low-Temperature Microchip Nonaqueous Capillary Electrophoresis of Aliphatic Primary Amines: Applications to Titan Chemistry
2013Co-Authors: Morgan L. Cable, Amanda M Stockton, Maria F Mora, Peter A WillisAbstract:We demonstrate microchip nonaqueous capillary electrophoresis (μNACE) analysis of primary aliphatic amines (C1–C18) in ethanol down to −20 °C as a first step in adapting microfluidic protocols for in situ analysis on Titan. To our knowledge, this is the first report of a nonaqueous separation at −20 °C on-chip. Limits of detection (LODs) ranged from 1.0 nM to 2.6 nM, and we identified several primary amines ranging in length from C2 to C16 in Titan aerosol analogue (tholin) samples; new amines were also detected in a tholin sample exposed to oxygen and liquid water. This preliminary work validates the sensitivity and efficacy of microfluidic chemical analysis of complex organics with relevance to Titan aerosols and surface deposits
Morgan L Cable - One of the best experts on this subject based on the ideXlab platform.
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identification of primary amines in Titan tholins using microchip nonaqueous capillary electrophoresis
Earth and Planetary Science Letters, 2014Co-Authors: Morgan L Cable, Amanda M Stockton, Maria F Mora, Sarah M Horst, Mark A Smith, Margaret A Tolbert, Peter A WillisAbstract:Abstract Titan, the moon of Saturn with a thick atmosphere and an active hydrocarbon-based weather cycle, is considered the best target in the solar system for the study of organic chemistry on a planetary scale. Microfluidic devices that employ liquid phase techniques such as capillary electrophoresis with ultrasensitive laser-induced fluorescence detection offer a unique solution for in situ analysis of complex organics on Titan. We previously reported a protocol for nonaqueous microfluidic analysis of primary aliphatic amines in ethanol, and demonstrated separations of short- and long-chain amines down to −20 °C. We have optimized this protocol further, and used it to analyze Titan aerosol analogues (tholins) generated in two separate laboratories under a variety of different conditions. Ethylamine was a major product in all samples, though significant differences in amine content were observed, in particular for long-chain amines (C12–C27). This work validates microfluidic chemical analysis of complex organics with relevance to Titan, and represents a significant first step in understanding tholin composition via targeted functional group analysis.
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low temperature microchip nonaqueous capillary electrophoresis of aliphatic primary amines applications to Titan chemistry
Analytical Chemistry, 2013Co-Authors: Morgan L Cable, Amanda M Stockton, Maria F Mora, Peter A WillisAbstract:We demonstrate microchip nonaqueous capillary electrophoresis (μNACE) analysis of primary aliphatic amines (C1–C18) in ethanol down to −20 °C as a first step in adapting microfluidic protocols for in situ analysis on Titan. To our knowledge, this is the first report of a nonaqueous separation at −20 °C on-chip. Limits of detection (LODs) ranged from 1.0 nM to 2.6 nM, and we identified several primary amines ranging in length from C2 to C16 in Titan aerosol analogue (tholin) samples; new amines were also detected in a tholin sample exposed to oxygen and liquid water. This preliminary work validates the sensitivity and efficacy of microfluidic chemical analysis of complex organics with relevance to Titan aerosols and surface deposits.
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Titan tholins simulating Titan organic chemistry in the cassini huygens era
Chemical Reviews, 2012Co-Authors: Morgan L Cable, Sarah M Horst, Mark A Smith, Robert Hodyss, Patricia Beauchamp, Peter WillisAbstract:Titan Tholins: Simulating Titan Organic Chemistry in the Cassini-Huygens Era Morgan L. Cable, Sarah M. H€orst, Robert Hodyss, Patricia M. Beauchamp, Mark A. Smith, and Peter A. Willis* NASA Jet Propulsion Laboratory, California Institute of Technology, Pasadena, California 91109, United States Cooperative Institute for Research in Environmental Sciences, University of Colorado, Boulder, Colorado 80309, United States Department of Chemistry, University of Arizona, Tucson, Arizona 85721, United States College of Natural Sciences and Mathematics, University of Houston, Houston, Texas 77004, United States
Amanda M Stockton - One of the best experts on this subject based on the ideXlab platform.
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identification of primary amines in Titan tholins using microchip nonaqueous capillary electrophoresis
Earth and Planetary Science Letters, 2014Co-Authors: Morgan L Cable, Amanda M Stockton, Maria F Mora, Sarah M Horst, Mark A Smith, Margaret A Tolbert, Peter A WillisAbstract:Abstract Titan, the moon of Saturn with a thick atmosphere and an active hydrocarbon-based weather cycle, is considered the best target in the solar system for the study of organic chemistry on a planetary scale. Microfluidic devices that employ liquid phase techniques such as capillary electrophoresis with ultrasensitive laser-induced fluorescence detection offer a unique solution for in situ analysis of complex organics on Titan. We previously reported a protocol for nonaqueous microfluidic analysis of primary aliphatic amines in ethanol, and demonstrated separations of short- and long-chain amines down to −20 °C. We have optimized this protocol further, and used it to analyze Titan aerosol analogues (tholins) generated in two separate laboratories under a variety of different conditions. Ethylamine was a major product in all samples, though significant differences in amine content were observed, in particular for long-chain amines (C12–C27). This work validates microfluidic chemical analysis of complex organics with relevance to Titan, and represents a significant first step in understanding tholin composition via targeted functional group analysis.
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low temperature microchip nonaqueous capillary electrophoresis of aliphatic primary amines applications to Titan chemistry
Analytical Chemistry, 2013Co-Authors: Morgan L Cable, Amanda M Stockton, Maria F Mora, Peter A WillisAbstract:We demonstrate microchip nonaqueous capillary electrophoresis (μNACE) analysis of primary aliphatic amines (C1–C18) in ethanol down to −20 °C as a first step in adapting microfluidic protocols for in situ analysis on Titan. To our knowledge, this is the first report of a nonaqueous separation at −20 °C on-chip. Limits of detection (LODs) ranged from 1.0 nM to 2.6 nM, and we identified several primary amines ranging in length from C2 to C16 in Titan aerosol analogue (tholin) samples; new amines were also detected in a tholin sample exposed to oxygen and liquid water. This preliminary work validates the sensitivity and efficacy of microfluidic chemical analysis of complex organics with relevance to Titan aerosols and surface deposits.
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Low-Temperature Microchip Nonaqueous Capillary Electrophoresis of Aliphatic Primary Amines: Applications to Titan Chemistry
2013Co-Authors: Morgan L. Cable, Amanda M Stockton, Maria F Mora, Peter A WillisAbstract:We demonstrate microchip nonaqueous capillary electrophoresis (μNACE) analysis of primary aliphatic amines (C1–C18) in ethanol down to −20 °C as a first step in adapting microfluidic protocols for in situ analysis on Titan. To our knowledge, this is the first report of a nonaqueous separation at −20 °C on-chip. Limits of detection (LODs) ranged from 1.0 nM to 2.6 nM, and we identified several primary amines ranging in length from C2 to C16 in Titan aerosol analogue (tholin) samples; new amines were also detected in a tholin sample exposed to oxygen and liquid water. This preliminary work validates the sensitivity and efficacy of microfluidic chemical analysis of complex organics with relevance to Titan aerosols and surface deposits
Maria F Mora - One of the best experts on this subject based on the ideXlab platform.
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identification of primary amines in Titan tholins using microchip nonaqueous capillary electrophoresis
Earth and Planetary Science Letters, 2014Co-Authors: Morgan L Cable, Amanda M Stockton, Maria F Mora, Sarah M Horst, Mark A Smith, Margaret A Tolbert, Peter A WillisAbstract:Abstract Titan, the moon of Saturn with a thick atmosphere and an active hydrocarbon-based weather cycle, is considered the best target in the solar system for the study of organic chemistry on a planetary scale. Microfluidic devices that employ liquid phase techniques such as capillary electrophoresis with ultrasensitive laser-induced fluorescence detection offer a unique solution for in situ analysis of complex organics on Titan. We previously reported a protocol for nonaqueous microfluidic analysis of primary aliphatic amines in ethanol, and demonstrated separations of short- and long-chain amines down to −20 °C. We have optimized this protocol further, and used it to analyze Titan aerosol analogues (tholins) generated in two separate laboratories under a variety of different conditions. Ethylamine was a major product in all samples, though significant differences in amine content were observed, in particular for long-chain amines (C12–C27). This work validates microfluidic chemical analysis of complex organics with relevance to Titan, and represents a significant first step in understanding tholin composition via targeted functional group analysis.
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low temperature microchip nonaqueous capillary electrophoresis of aliphatic primary amines applications to Titan chemistry
Analytical Chemistry, 2013Co-Authors: Morgan L Cable, Amanda M Stockton, Maria F Mora, Peter A WillisAbstract:We demonstrate microchip nonaqueous capillary electrophoresis (μNACE) analysis of primary aliphatic amines (C1–C18) in ethanol down to −20 °C as a first step in adapting microfluidic protocols for in situ analysis on Titan. To our knowledge, this is the first report of a nonaqueous separation at −20 °C on-chip. Limits of detection (LODs) ranged from 1.0 nM to 2.6 nM, and we identified several primary amines ranging in length from C2 to C16 in Titan aerosol analogue (tholin) samples; new amines were also detected in a tholin sample exposed to oxygen and liquid water. This preliminary work validates the sensitivity and efficacy of microfluidic chemical analysis of complex organics with relevance to Titan aerosols and surface deposits.
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Low-Temperature Microchip Nonaqueous Capillary Electrophoresis of Aliphatic Primary Amines: Applications to Titan Chemistry
2013Co-Authors: Morgan L. Cable, Amanda M Stockton, Maria F Mora, Peter A WillisAbstract:We demonstrate microchip nonaqueous capillary electrophoresis (μNACE) analysis of primary aliphatic amines (C1–C18) in ethanol down to −20 °C as a first step in adapting microfluidic protocols for in situ analysis on Titan. To our knowledge, this is the first report of a nonaqueous separation at −20 °C on-chip. Limits of detection (LODs) ranged from 1.0 nM to 2.6 nM, and we identified several primary amines ranging in length from C2 to C16 in Titan aerosol analogue (tholin) samples; new amines were also detected in a tholin sample exposed to oxygen and liquid water. This preliminary work validates the sensitivity and efficacy of microfluidic chemical analysis of complex organics with relevance to Titan aerosols and surface deposits
Mark A Smith - One of the best experts on this subject based on the ideXlab platform.
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identification of primary amines in Titan tholins using microchip nonaqueous capillary electrophoresis
Earth and Planetary Science Letters, 2014Co-Authors: Morgan L Cable, Amanda M Stockton, Maria F Mora, Sarah M Horst, Mark A Smith, Margaret A Tolbert, Peter A WillisAbstract:Abstract Titan, the moon of Saturn with a thick atmosphere and an active hydrocarbon-based weather cycle, is considered the best target in the solar system for the study of organic chemistry on a planetary scale. Microfluidic devices that employ liquid phase techniques such as capillary electrophoresis with ultrasensitive laser-induced fluorescence detection offer a unique solution for in situ analysis of complex organics on Titan. We previously reported a protocol for nonaqueous microfluidic analysis of primary aliphatic amines in ethanol, and demonstrated separations of short- and long-chain amines down to −20 °C. We have optimized this protocol further, and used it to analyze Titan aerosol analogues (tholins) generated in two separate laboratories under a variety of different conditions. Ethylamine was a major product in all samples, though significant differences in amine content were observed, in particular for long-chain amines (C12–C27). This work validates microfluidic chemical analysis of complex organics with relevance to Titan, and represents a significant first step in understanding tholin composition via targeted functional group analysis.
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nmr identification of hexamethylenetetramine and its precursor in Titan tholins implications for Titan prebiotic chemistry
Icarus, 2012Co-Authors: Guangxin Lin, Mark A SmithAbstract:Abstract The reddish brown organic haze surrounding Titan has been investigated using methods including remote observation, direct exploration (the Cassini mission) and laboratory simulations, but its formation mechanism and the contributing chemical structures and prebiotic potential are still not well understood. We report here the structural investigation of the 13 C and 15 N labeled, simulated Titan haze aerosol (tholin) using solution-state NMR. These spectra demonstrate a material composed of a mixture of moderate polymer and small molecules. Hexamethylenetetramine (HMT) is identified as the major small molecule component in the Titan tholin and its precursor (1,3,5-hexahydrotriazine) is also detected. We discuss the formation mechanism of HMT and its implications for Titan and early Earth prebiotic chemistry.
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Titan tholins simulating Titan organic chemistry in the cassini huygens era
Chemical Reviews, 2012Co-Authors: Morgan L Cable, Sarah M Horst, Mark A Smith, Robert Hodyss, Patricia Beauchamp, Peter WillisAbstract:Titan Tholins: Simulating Titan Organic Chemistry in the Cassini-Huygens Era Morgan L. Cable, Sarah M. H€orst, Robert Hodyss, Patricia M. Beauchamp, Mark A. Smith, and Peter A. Willis* NASA Jet Propulsion Laboratory, California Institute of Technology, Pasadena, California 91109, United States Cooperative Institute for Research in Environmental Sciences, University of Colorado, Boulder, Colorado 80309, United States Department of Chemistry, University of Arizona, Tucson, Arizona 85721, United States College of Natural Sciences and Mathematics, University of Houston, Houston, Texas 77004, United States
