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Campos, Karinny Ferreira - One of the best experts on this subject based on the ideXlab platform.
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Eastern equine encephalitis on Marajó Island, Pará state, Brazil
'FapUNIFESP (SciELO)', 2013Co-Authors: Campos, Karinny Ferreira, Cairo Henrique Sousa De ,oliveira, Reis, Alessandra Dos Santos Belo, Yamasaki, Elise Miyuki, Brito, Marilene De Farias, Stefano Juliano Tavares De ,andrade, Duarte, Marcos Dutra, Barbosa Neto, José DiomedesAbstract:Nine cases of equine encephalomyelitis on Marajó Island, state of Pará, Brazil, were studied. The affected horses had difficulty to stand, walked in circles, with marked depression, closed eyelids, Tongue Paralysis, muscle tremors, bruxism, anorexia and dehydration. Some had their ear and eyelid reflexes diminished, decreased Tongue tone and tachycardia; laid down frequently they kept their head on the chest. Often they were seen resting their head on tree trunks or fences. At necropsy, hemorrhages of the meninges and spinal cord, and in some animals also adhesion of the meninges were found. Histologically there was diffuse encephalitis affecting mainly the gray matter, with meningitis and choroiditis. Presence of perivascular cuffs consisting of mononuclear inflammatory cells was observed. From two horses the Eastern equine encephalitis virus was identified by semi-nested reverse transcription polymerase chain reaction (semi-nested RT-PCR).Nove casos de encefalomielite equina foram estudados na Ilha de Marajó, estado do Pará, Brasil. Os equinos apresentavam dificuldade em se manter em estação, andavam em círculo, tinham acentuada depressão, pálpebras cerradas, paralisia da língua, tremores musculares, bruxismo, anorexia e desidratação. Alguns apresentavam diminuição dos reflexos auricular, palpebral, de ameaça, diminuição do tônus da língua e taquicardia. Posição de auto-auscultação foi observada com frequência. Os animais muitas vezes eram encontrados apoiados em troncos e cercas para se manterem em estação. À necropsia verificou-se hemorragia das leptomeninges e da medula, alguns apresentaram ainda aderência das leptomeninges. À histopatologia verificou-se encefalite difusa que afetava principalmente a substância cinzenta, com meningite e coroidite. Foi observada perivasculite mononuclear. Em dois equinos identificou-se o vírus da encefalomielite equina Leste pela reação de Semi-Nested transcrição reversa de polimerase em cadeia (Semi-Nested RT-PCR)
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Encefalomielite equina Leste na Ilha de Marajó, Pará
Programa de Pós-Graduação em Ciência Animal, 2012Co-Authors: Campos, Karinny FerreiraAbstract:Nine cases of equine encephalomyelitis were studied in the Marajó Island, State of Pará, Brazil. The animals had difficulty in maintaining a station, walk in a circle, marked depression, eyelids closed, Tongue Paralysis, muscle tremors, bruxism, anorexia and dehydration. Some had their ear and eyelid reflexes diminished, decreased Tongue tone and tachycardia. Position of self-hearing was observed frequently. The animals were often found leaning on tree trunks and fences to keep themselves on station. At necropsy, they showed hemorrhage of the meninges and spinal cord, and some animals also showed adhesion of the meninges. Histologically there was diffuse encephalitis affecting mainly the gray matter, with meningitis and choroiditis. It was observed the presence of perivascular cuffs consisting of mononuclear inflammatory cells. In two animals it was possible to identificate the Eastern equine encephalitis virus by semi-nested reverse transcription polymerase chain reaction (semi-nested RT-PCR).Nove casos de encefalomielite equina foram estudados na Ilha de Marajó, estado do Pará, Brasil. Os animais apresentavam dificuldade em se manter em estação, andar em círculo, acentuada depressão, pálpebras cerradas, paralisia da língua, tremores musculares, bruxismo, anorexia e desidratação. Alguns apresentavam diminuição dos reflexos auricular, palpebral, de ameaça, diminuição do tônus da língua e taquicardia. Posição de auto-auscultação foi observada com frequência. Os animais muitas vezes eram encontrados apoiados em troncos e cercas para se manterem em estação. À necropsia verificou-se hemorragia das leptomeninges e medula, alguns animais apresentaram ainda aderencia das leptomeninges. Na histopatologia verificou-se encefalite difusa afetando principalmente a substância cinzenta, com meningite e coroidite. Foi observada presença de manguitos perivasculares constituídos por células inflamatórias mononucleadas. Em dois animais identificou-se o Eastern equine encephalitis virus por semi nested transcrição reversa reação de polimerase em cadeia (Semi-Nested RT-PCR)
M S Mouradian - One of the best experts on this subject based on the ideXlab platform.
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LESSON OF THE MONTH Transient
2016Co-Authors: M S MouradianAbstract:total Tongue Paralysis from simultaneous central and peripheral lesion
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transient total Tongue Paralysis from simultaneous central and peripheral lesions
Journal of Neurology Neurosurgery and Psychiatry, 2001Co-Authors: M S Mouradian, K M Chan, T Jeerakathil, Ashfaq ShuaibAbstract:Lower cranial nerve palsies in various combinations involving the hypoglossal, glossopharyngeal, vagal, and the accessory nerves occur in internal carotid artery (ICA) dissection.1-8 17 The hypoglossal nerve (cn-XII) is most often affected. It is suggested that the close proximity of these nerves to the cervical ICA may subject them to mechanical injury either by the expansion of the dissected artery or by aneurysm formation.1 3 9 10 Dissection of the ICA may cause transient or permanent disruption of the blood supply to these cranial nerves.6 11 Therefore, cranial nerve injuries may result from “mechanical, embolic, or haemodynamic” processes caused by ICA dissection.6 This hypothesis is supported by anatomical and clinical findings.2 6 12Each half of the genioglossus muscle that protrudes the Tongue is innervated by contralateral corticobulbar (crossed) fibres whereas all other intrinsic and extrinsic Tongue muscles that move the Tongue within the mouth in all directions have bilateral cortical innervation.13 14 Unilateral cortical lesion in the topography representing the Tongue may therefore cause contralateral genioglossus muscle weakness, resulting in deviation of the protruded Tongue away from the side of the cortical lesion. By contrast, cn-XII injury causes ipsilateral genioglossus muscle weakness; hence the protruded Tongue deviates to the side of the injured nerve. When clinical history is unrevealing and lower cranial nerves are involved, diagnosing ICA dissection becomes challenging. We present a patient with complete Tongue Paralysis that resulted from a frontal lobe stroke and a cn-XII injury, both caused by an ipsilateral ICA dissection. In the absence of binuclear cn-XII lesion or a pseudobulbar syndrome, localisation of the lesions responsible for the complete Tongue Paralysis can be difficult. This patient illustrates that in the presence of bilateral acute Tongue Paralysis …
Ashfaq Shuaib - One of the best experts on this subject based on the ideXlab platform.
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transient total Tongue Paralysis from simultaneous central and peripheral lesions
Journal of Neurology Neurosurgery and Psychiatry, 2001Co-Authors: M S Mouradian, K M Chan, T Jeerakathil, Ashfaq ShuaibAbstract:Lower cranial nerve palsies in various combinations involving the hypoglossal, glossopharyngeal, vagal, and the accessory nerves occur in internal carotid artery (ICA) dissection.1-8 17 The hypoglossal nerve (cn-XII) is most often affected. It is suggested that the close proximity of these nerves to the cervical ICA may subject them to mechanical injury either by the expansion of the dissected artery or by aneurysm formation.1 3 9 10 Dissection of the ICA may cause transient or permanent disruption of the blood supply to these cranial nerves.6 11 Therefore, cranial nerve injuries may result from “mechanical, embolic, or haemodynamic” processes caused by ICA dissection.6 This hypothesis is supported by anatomical and clinical findings.2 6 12Each half of the genioglossus muscle that protrudes the Tongue is innervated by contralateral corticobulbar (crossed) fibres whereas all other intrinsic and extrinsic Tongue muscles that move the Tongue within the mouth in all directions have bilateral cortical innervation.13 14 Unilateral cortical lesion in the topography representing the Tongue may therefore cause contralateral genioglossus muscle weakness, resulting in deviation of the protruded Tongue away from the side of the cortical lesion. By contrast, cn-XII injury causes ipsilateral genioglossus muscle weakness; hence the protruded Tongue deviates to the side of the injured nerve. When clinical history is unrevealing and lower cranial nerves are involved, diagnosing ICA dissection becomes challenging. We present a patient with complete Tongue Paralysis that resulted from a frontal lobe stroke and a cn-XII injury, both caused by an ipsilateral ICA dissection. In the absence of binuclear cn-XII lesion or a pseudobulbar syndrome, localisation of the lesions responsible for the complete Tongue Paralysis can be difficult. This patient illustrates that in the presence of bilateral acute Tongue Paralysis …
J C Alvarez-cermeño - One of the best experts on this subject based on the ideXlab platform.
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Isolated total Tongue Paralysis as a manifestation of bilateral medullary infarction
Journal of neurology neurosurgery and psychiatry, 2003Co-Authors: J Benito-león, J C Alvarez-cermeñoAbstract:Isolated acute bilateral hypoglossal nerve (CXII) Paralysis is a very rare clinical condition which has been described in the context of traumatic mechanical injuries to the nerves.1 The two nuclei of CXII, located at the tegmentum of the medulla oblongata, are in close proximity and may be damaged at the same time.2 However, isolated bilateral CXII Paralysis has not been described in cases of medullary infarction. We report a patient presenting with isolated complete Tongue Paralysis and a small ischaemic area in the medulla affecting both CXII nuclei exclusively. A 49 year old woman with a history of primary biliary cirrhosis presented to the emergency room with acute dysarthria, swallowing difficulty, and inability to protrude her Tongue. She was unable to eat, drink, or handle saliva. She denied vertigo, dizziness, nausea, unsteady gait, numbness, or weakness. Examination showed that she was alert and responsive but was dysarthric and unable to initiate a swallow. Pupils were 3 mm in diameter, equal, and reactive to light and accommodation Extraocular movements were full. There was no ptosis and the corneal reflex was present bilaterally. Sensation was intact to light touch and pin prick. There was no spontaneous or gaze nystagmus, saccadic pursuit, or ocular dysmetria. Facial …
Ingho Chen - One of the best experts on this subject based on the ideXlab platform.
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atlantoaxial rotatory dislocation with hypoglossal nerve palsy in a patient with ankylosing spondylitis a case report
Journal of Bone and Joint Surgery American Volume, 2005Co-Authors: Juiteng Chien, Ingho ChenAbstract:A tlantoaxial subluxation is a rare but well-recognized complication of ankylosing spondylitis1-7. Anterior subluxation is most common, but vertical subluxation of the dens may also occur and may result in cervical myelopathy, lower cranial nerve palsy, or even sudden death due to cervicomedullary compression8-10. Tongue Paralysis due to isolated hypoglossal nerve palsy is also rare11-13. In addition to occurring in patients with rheumatoid arthritis14,15, hypoglossal nerve palsy has been noted in association with a number of pathological conditions such as occipital condylar fracture, metastatic tumor in the skull base, and infection16. We report on a patient with ankylosing spondylitis who presented with life-threatening atlantoaxial rotatory dislocation and bilateral hypoglossal nerve palsy and was successfully treated with halo-dependent traction followed by occipitocervical arthrodesis. To the best of our knowledge, bilateral hypoglossal nerve palsy with Tongue Paralysis arising from atlantoaxial rotatory dislocation has never been reported in a patient with ankylosing spondylitis. The patient consented to have the data concerning the case submitted for publication. I n October 2001, a forty-nine-year-old man with a thirty-year history of ankylosing spondylitis presented with severe torticollis, a chin-on-chest deformity, and a protruded Tongue. These conditions had developed three months before admission and had progressed rapidly over the preceding four weeks. The patient reported no history of trauma to the head or neck in the preceding months. Neurological examination revealed generalized hyper-reflexia, sustained ankle clonus, and positive Babinski signs. Muscle power was decreased (grade 3 of 5) throughout both the upper and lower extremities. The …