The Experts below are selected from a list of 1629 Experts worldwide ranked by ideXlab platform
Suresh Kotagal - One of the best experts on this subject based on the ideXlab platform.
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massive Tongue Swelling in refractory status epilepticus treated with high dose pentobarbital
Neurocritical Care, 2009Co-Authors: Teng Ji, Alexander Y Zubkov, Eelco F M Wijdicks, Edward M Manno, Alejandro A Rabinstein, Suresh KotagalAbstract:Introduction The potential causes of acquired macroglossia are extensive. The authors report two cases of subacute marked Tongue Swelling resulting in airway compromise in patients with refractory status epilepticus requiring prolonged pentobarbital coma.
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massive Tongue Swelling in refractory status epilepticus treated with high dose pentobarbital
Neurocritical Care, 2009Co-Authors: Alexander Y Zubkov, Eelco F M Wijdicks, Edward M Manno, Alejandro A Rabinstein, Suresh KotagalAbstract:The potential causes of acquired macroglossia are extensive. The authors report two cases of subacute marked Tongue Swelling resulting in airway compromise in patients with refractory status epilepticus requiring prolonged pentobarbital coma. The hospitalization histories of the reported patients were retrospectively reviewed. The Tongue Swelling completely resolved in one case and significantly improved in the other after discontinuation of pentobarbital infusion or switching to phenobarbital. The authors speculate that the causes were multifarious, likely a combination of localized angioedema due to barbiturate vehicle and triggered by an initial Tongue bite. Progressive Tongue Swelling causing airway obstruction can occur well beyond the acute phase of status epilepticus and may potentially cause problems with extubation in nontracheotomized patients.
S Minota - One of the best experts on this subject based on the ideXlab platform.
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Repeated Massive Tongue Swelling Due to the Combined Use of Estramustine Phosphate and Angiotensin-Converting Enzyme Inhibitor
2015Co-Authors: T Morita, S MinotaAbstract:Abstract. A 70-year-old man presenting with a chief complaint of Tongue Swelling had been diagnosed with prostate cancer 1 year earlier. He had been on an oral angiotensin-converting enzyme inhibitor (ACE) inhibitor for hypertension for 20 years. Two months before the fi rst of 4 episodes of Tongue Swelling within a period of 40 days, he had been prescribed oral estramustine phosphate (EMP) for the prostate cancer. He was admitted to our hospital for the evaluation after massive Swelling of the Tongue and epiglottis which necessitated tracheotomy. Food allergies, allergic reactions to environmental factors, and hereditary angioneurotic edema were excluded. Massive Swelling of the Tongue and epiglottis disappeared completely after EMP was discontinued. We concluded that angioedema was induced by EMP used concurrently with the ACE inhibitor. Key Words: Estramustine phosphate. Angiotensin-converting enzyme inhibitor. Angioedema. Tracheotomy. Prostate cancer. Resumen. A un paciente de 70 años de edad con edema lingual como motivo principal de consulta, le había sido diagnosticado un cáncer de próstata un año antes. Había estado tomando un inhibidor oral de la enzima convertidora de la angiotensina (IECA) para el tratamiento de la hipertensión durante 20 años. Dos meses antes del primero de los cuatro episodios de edema de la lengua, se le había prescrito fosfato de estramustina oral para el cáncer de próstata. Fue ingresado en nuestro hospital para su observación tras el edema lingual masivo y la epigloti
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repeated massive Tongue Swelling due to the combined use of estramustine phosphate and angiotensin converting enzyme inhibitor
Journal of Investigational Allergology and Clinical Immunology, 2006Co-Authors: Yasuyuki Kamata, T Morita, Masahiro Iwamoto, Takeshi Kamimura, E Kanashiki, Taku Yoshio, Hitoaki Okazaki, S MinotaAbstract:A 70-year-old man presenting with a chief complaint of Tongue Swelling had been diagnosed with prostate cancer 1 year earlier. He had been on an oral angiotensin-converting enzyme inhibitor (ACE) inhibitor for hypertension for 20 years. Two months before the fi rst of 4 episodes of Tongue Swelling within a period of 40 days, he had been prescribed oral estramustine phosphate (EMP) for the prostate cancer. He was admitted to our hospital for the evaluation after massive Swelling of the Tongue and epiglottis which necessitated tracheotomy. Food allergies, allergic reactions to environmental factors, and hereditary angioneurotic edema were excluded. Massive Swelling of the Tongue and epiglottis disappeared completely after EMP was discontinued. We concluded that angioedema was induced by EMP used concurrently with the ACE inhibitor.
David E Eibling - One of the best experts on this subject based on the ideXlab platform.
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supraglottic Swelling may not correlate with Tongue Swelling in angiotensin converting enzyme inhibitor induced angioedema
Laryngoscope, 2009Co-Authors: Shashank Saxena, Brian T Gierl, David E EiblingAbstract:Angioneurotic edema of upper airway tissues due to angiotensin converting enzyme inhibitor (ACEI) usage is a known perioperative complication of this class of medications. Swelling can begin rapidly, and typically involves the Tongue and oral cavity. We have recently encountered four cases in which supraglottic edema developed after onset of Tongue Swelling and progressed despite resolving Tongue edema. We present a representative case. This observation suggests that all patients with ACEI-induced angioedema should undergo laryngeal fiberoptic examination and appropriate airway management.
Carlos A Camargo - One of the best experts on this subject based on the ideXlab platform.
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multicenter study of patients with angiotensin converting enzyme inhibitor induced angioedema who present to the emergency department
Annals of Allergy Asthma & Immunology, 2008Co-Authors: Aleena Banerji, Michelle Blanda, Frank Lovecchio, Brian D Snyder, Sunday Clark, Carlos A CamargoAbstract:Background Recent data are lacking about the number of patients with angiotensin-converting enzyme inhibitor (ACEI)-induced angioedema who present to the emergency department (ED). Current management of the condition and clinical outcomes also are not known. Objective To describe the clinical epidemiology of ACEI-induced angioedema in patients who present to the ED. Methods We performed a medical record review of ACEI-induced angioedema in patients who presented to 5 EDs in the Emergency Medicine Network. A structured data abstraction form was used to collect each patient's demographic factors, medical history, and details about the angioedema that prompted the ED visit. The medical record review also focused on treatment provided in the ED and subsequent need for hospitalization. Results We identified a total of 220 patients with ACEI-induced angioedema. The frequency of ACEI-induced angioedema among all patients with angioedema who presented to the ED was 30% (95% confidence interval, 26%-34%). The annual rate of visits for ACEI-induced angioedema was 0.7 per 10,000 ED visits. The most frequent presenting signs were shortness of breath, lip and Tongue Swelling, and laryngeal edema. Most patients (58%) were sent home directly from the ED, whereas 12% were regular inpatient admissions, 11% were admitted to the intensive care unit, and 18% were admitted under observation status ( Conclusion ACEI-induced angioedema accounted for almost one-third of angioedema treated in the ED, although it remains a rare ED presentation. A subgroup of these patients still needs inpatient hospitalization for management of upper airway angioedema.
Alexander Y Zubkov - One of the best experts on this subject based on the ideXlab platform.
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massive Tongue Swelling in refractory status epilepticus treated with high dose pentobarbital
Neurocritical Care, 2009Co-Authors: Teng Ji, Alexander Y Zubkov, Eelco F M Wijdicks, Edward M Manno, Alejandro A Rabinstein, Suresh KotagalAbstract:Introduction The potential causes of acquired macroglossia are extensive. The authors report two cases of subacute marked Tongue Swelling resulting in airway compromise in patients with refractory status epilepticus requiring prolonged pentobarbital coma.
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massive Tongue Swelling in refractory status epilepticus treated with high dose pentobarbital
Neurocritical Care, 2009Co-Authors: Alexander Y Zubkov, Eelco F M Wijdicks, Edward M Manno, Alejandro A Rabinstein, Suresh KotagalAbstract:The potential causes of acquired macroglossia are extensive. The authors report two cases of subacute marked Tongue Swelling resulting in airway compromise in patients with refractory status epilepticus requiring prolonged pentobarbital coma. The hospitalization histories of the reported patients were retrospectively reviewed. The Tongue Swelling completely resolved in one case and significantly improved in the other after discontinuation of pentobarbital infusion or switching to phenobarbital. The authors speculate that the causes were multifarious, likely a combination of localized angioedema due to barbiturate vehicle and triggered by an initial Tongue bite. Progressive Tongue Swelling causing airway obstruction can occur well beyond the acute phase of status epilepticus and may potentially cause problems with extubation in nontracheotomized patients.