The Experts below are selected from a list of 17922 Experts worldwide ranked by ideXlab platform
Mainul Haque - One of the best experts on this subject based on the ideXlab platform.
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Chronic Tonsillitis and biofilms: a brief overview of treatment modalities
Journal of inflammation research, 2018Co-Authors: Muhamad Abu Bakar, Judy Mckimm, Seraj Zohurul Haque, Anwarul Azim Majumder, Mainul HaqueAbstract:Recurrent Tonsillitis is described as when an individual suffers from several attacks of Tonsillitis per year. Chronic and recurrent Tonsillitis both cause repeated occurrences of inflamed tonsils which have a significant impact on a patient's quality of life. Numerous children suffer from recurrent Tonsillitis and sore throats, and these illnesses become part of their life. Antimicrobials can provide temporary relief, but in many cases, Tonsillitis recurs. The cause of such recurrent infections have been identified as microorganisms which often create biofilms and a repository of infection in the wet and warm folds of the tonsils. This review discusses different treatment modalities, their advantages and disadvantages, and new treatment options focusing on biofilms. All treatment options should be selected based on evidence and individual need.
Per Magnus - One of the best experts on this subject based on the ideXlab platform.
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Recurrent Tonsillitis Among Twins
2017Co-Authors: Ellen Kvestad, Kristian Tambs, Jennifer R Harris, Kari Jorunn, Per MagnusAbstract:Results: The lifetime prevalence of recurrent Tonsillitis was 11.7% (95% confidence interval, 11.0%-12.3%), with a significant predominance of female cases. The tetrachoric correlations for monozygotic twins were 0.71 for males and 0.60 for females. For dizygotic twins, the correlations were 0.12 for males, 0.14 for females, and 0.24 for dizygotic pairs of opposite sex. Structural equation modeling indicated that genetic effects explained 62% of the variation in the liability of recurrent Tonsillitis. The remaining variance was attributed to individual environmental effects. There was no evidence of sex-specific genetic effects on the liability of recurrent Tonsillitis. Conclusion: There is evidence for a substantial genetic predisposition for recurrent Tonsillitis.
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Recurrent otitis media and Tonsillitis: common disease predisposition
International Journal of Pediatric Otorhinolaryngology, 2006Co-Authors: Ellen Kvestad, Kristian Tambs, Espen Røysamb, Kari J. Kværner, Jennifer R Harris, Per MagnusAbstract:Summary Objective To estimate the relative contribution of genetic and environmental effects to the association between recurrent otitis media and recurrent Tonsillitis. Methods Self-report questionnaire data from a population-based cohort of 9479 Norwegian twins born from 1967 to 1979. Recurrent otitis media and recurrent Tonsillitis were main outcome measures. Structural equation modelling was used to fit alternative biometric models to the twin data and to estimate the relative contribution of genetic and environmental effects to the association between otitis media and Tonsillitis. Results The lifetime prevalence was 11.7% (95% CI: 11.0–12.3) for recurrent Tonsillitis and 11.2% (95% CI 10.5–11.9) for recurrent otitis media. Tetrachoric correlations were greater in monozygotic than in dizygotic twins in both males and females. A model specifying additive genetic effects and individual environmental effects for otitis media and Tonsillitis and non-additive genetic effects for Tonsillitis yielded the best fit. There was no evidence for sex differences in the genetic source or magnitude of the genetic effects. There was a substantial overlap in genetic factors influencing variation in liability to otitis media and Tonsillitis. Conclusion Common genetic factors contribute substantially to comorbidity between recurrent otitis media and recurrent Tonsillitis.
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Heritability of Recurrent Tonsillitis
Archives of Otolaryngology-head & Neck Surgery, 2005Co-Authors: Ellen Kvestad, Kristian Tambs, Espen Røysamb, Kari J. Kværner, Jennifer R Harris, Per MagnusAbstract:Objective To estimate the relative contribution of genetic and environmental effects on the variance in the liability of recurrent Tonsillitis. Design Retrospective questionnaire data from a population-based cohort. Setting Population-based data from Norway. Participants A total of 9479 Norwegian twins born between January 1, 1967, and December 31, 1979, identified through the Medical Birth Registry of Norway. Main Outcome Measure Recurrent Tonsillitis. Results The lifetime prevalence of recurrent Tonsillitis was 11.7% (95% confidence interval, 11.0%-12.3%), with a significant predominance of female cases. The tetrachoric correlations for monozygotic twins were 0.71 for males and 0.60 for females. For dizygotic twins, the correlations were 0.12 for males, 0.14 for females, and 0.24 for dizygotic pairs of opposite sex. Structural equation modeling indicated that genetic effects explained 62% of the variation in the liability of recurrent Tonsillitis. The remaining variance was attributed to individual environmental effects. There was no evidence of sex-specific genetic effects on the liability of recurrent Tonsillitis. Conclusion There is evidence for a substantial genetic predisposition for recurrent Tonsillitis.
Pesus Chou - One of the best experts on this subject based on the ideXlab platform.
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the impact of prior Tonsillitis and treatment modality on the recurrence of peritonsillar abscess a nationwide cohort study
PLOS ONE, 2014Co-Authors: Yingpiao Wang, Maoche Wang, Hungching Lin, Pesus ChouAbstract:Background Studies suggest an increased risk of peritonsillar abscess (PTA) recurrence in patients with prior Tonsillitis. However, this association is inconsistent and could be confounded by different treatment modalities. This study aimed to assess the risk of recurrence among PTA patients with different degrees of prior Tonsillitis and treatment modalities, and the role of tonsillectomy in current practice. Methods All in-patients with peritonsillar abscess between January 2001 and December 2009 were identified in a nationwide, retrospective cohort study. Recurrence was defined as the first occurrence of PTA ≧30 days from the initial PTA. Factors independently associated with recurrence were analyzed using Cox proportional hazard model after adjusting for demographic and clinical data. Results There were 28,837 patients, with a 5.15% recurrence rate and 4.74 years of follow-up. The recurrence rates were significantly higher among subjects with more than five prior Tonsillitis or 1–4 prior Tonsillitis compared to those without prior Tonsillitis (adjusted hazard ratio, 2.82 [95% confidence interval, 2.39–3.33] and 1.59 [95% CI: 1.38–1.82]). The adjusted HR in patients treated with needle aspiration was 1.08 compared to those treated with incision & drainage (95% CI: 0.85–1.38). After age stratification, the adjusted HRs of more than five prior Tonsillitis increased to 2.92 and 3.50 in patients aged ≦18 and 19–29 years respectively. The adjusted HR ofneedle aspiration only increased in patients ≦18 years old (aHR: 1.98 [95% CI: 0.99–3.97]). The overall tonsillectomy rate was 1.48% during our study period. Conclusions The risk of PTA recurrence increases with higher degrees of prior Tonsillitis in all age groups and management by needle aspiration only in the pediatric population. Patients younger than 30 years old with PTA and more than five prior Tonsillitis have the greatest risk of recurrence.
Muhamad Abu Bakar - One of the best experts on this subject based on the ideXlab platform.
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Chronic Tonsillitis and biofilms: a brief overview of treatment modalities
Journal of inflammation research, 2018Co-Authors: Muhamad Abu Bakar, Judy Mckimm, Seraj Zohurul Haque, Anwarul Azim Majumder, Mainul HaqueAbstract:Recurrent Tonsillitis is described as when an individual suffers from several attacks of Tonsillitis per year. Chronic and recurrent Tonsillitis both cause repeated occurrences of inflamed tonsils which have a significant impact on a patient's quality of life. Numerous children suffer from recurrent Tonsillitis and sore throats, and these illnesses become part of their life. Antimicrobials can provide temporary relief, but in many cases, Tonsillitis recurs. The cause of such recurrent infections have been identified as microorganisms which often create biofilms and a repository of infection in the wet and warm folds of the tonsils. This review discusses different treatment modalities, their advantages and disadvantages, and new treatment options focusing on biofilms. All treatment options should be selected based on evidence and individual need.
Ellen Kvestad - One of the best experts on this subject based on the ideXlab platform.
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Recurrent Tonsillitis Among Twins
2017Co-Authors: Ellen Kvestad, Kristian Tambs, Jennifer R Harris, Kari Jorunn, Per MagnusAbstract:Results: The lifetime prevalence of recurrent Tonsillitis was 11.7% (95% confidence interval, 11.0%-12.3%), with a significant predominance of female cases. The tetrachoric correlations for monozygotic twins were 0.71 for males and 0.60 for females. For dizygotic twins, the correlations were 0.12 for males, 0.14 for females, and 0.24 for dizygotic pairs of opposite sex. Structural equation modeling indicated that genetic effects explained 62% of the variation in the liability of recurrent Tonsillitis. The remaining variance was attributed to individual environmental effects. There was no evidence of sex-specific genetic effects on the liability of recurrent Tonsillitis. Conclusion: There is evidence for a substantial genetic predisposition for recurrent Tonsillitis.
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Recurrent otitis media and Tonsillitis: common disease predisposition
International Journal of Pediatric Otorhinolaryngology, 2006Co-Authors: Ellen Kvestad, Kristian Tambs, Espen Røysamb, Kari J. Kværner, Jennifer R Harris, Per MagnusAbstract:Summary Objective To estimate the relative contribution of genetic and environmental effects to the association between recurrent otitis media and recurrent Tonsillitis. Methods Self-report questionnaire data from a population-based cohort of 9479 Norwegian twins born from 1967 to 1979. Recurrent otitis media and recurrent Tonsillitis were main outcome measures. Structural equation modelling was used to fit alternative biometric models to the twin data and to estimate the relative contribution of genetic and environmental effects to the association between otitis media and Tonsillitis. Results The lifetime prevalence was 11.7% (95% CI: 11.0–12.3) for recurrent Tonsillitis and 11.2% (95% CI 10.5–11.9) for recurrent otitis media. Tetrachoric correlations were greater in monozygotic than in dizygotic twins in both males and females. A model specifying additive genetic effects and individual environmental effects for otitis media and Tonsillitis and non-additive genetic effects for Tonsillitis yielded the best fit. There was no evidence for sex differences in the genetic source or magnitude of the genetic effects. There was a substantial overlap in genetic factors influencing variation in liability to otitis media and Tonsillitis. Conclusion Common genetic factors contribute substantially to comorbidity between recurrent otitis media and recurrent Tonsillitis.
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Heritability of Recurrent Tonsillitis
Archives of Otolaryngology-head & Neck Surgery, 2005Co-Authors: Ellen Kvestad, Kristian Tambs, Espen Røysamb, Kari J. Kværner, Jennifer R Harris, Per MagnusAbstract:Objective To estimate the relative contribution of genetic and environmental effects on the variance in the liability of recurrent Tonsillitis. Design Retrospective questionnaire data from a population-based cohort. Setting Population-based data from Norway. Participants A total of 9479 Norwegian twins born between January 1, 1967, and December 31, 1979, identified through the Medical Birth Registry of Norway. Main Outcome Measure Recurrent Tonsillitis. Results The lifetime prevalence of recurrent Tonsillitis was 11.7% (95% confidence interval, 11.0%-12.3%), with a significant predominance of female cases. The tetrachoric correlations for monozygotic twins were 0.71 for males and 0.60 for females. For dizygotic twins, the correlations were 0.12 for males, 0.14 for females, and 0.24 for dizygotic pairs of opposite sex. Structural equation modeling indicated that genetic effects explained 62% of the variation in the liability of recurrent Tonsillitis. The remaining variance was attributed to individual environmental effects. There was no evidence of sex-specific genetic effects on the liability of recurrent Tonsillitis. Conclusion There is evidence for a substantial genetic predisposition for recurrent Tonsillitis.
