The Experts below are selected from a list of 435 Experts worldwide ranked by ideXlab platform
Jason M. Konter - One of the best experts on this subject based on the ideXlab platform.
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A case of Tracheobronchomegaly
European journal of internal medicine, 2017Co-Authors: Jirat Chenbhanich, Juan Villa-camacho, Jason M. KonterAbstract:Tracheobronchomegaly (Mounier-Kuhn syndrome) is a rare condition characterized by an abnormally enlarged trachea and main bronchi. Herein, we present a case of 79-year-old male with idiopathic pulmonary fibrosis and acute hypoxemic respiratory failure due to multilobar pneumonia. Computed tomography of the chest demonstrated a markedly dilated trachea, with the transverse diameter of 31mm and the sagittal diameter of 30mm. The clinical manifestations as well as its diagnosis, classification, and treatment are discussed.
Anna Lehman - One of the best experts on this subject based on the ideXlab platform.
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A Clinical Classification Scheme for Tracheobronchomegaly (Mounier-Kuhn Syndrome)
Lung, 2015Co-Authors: Jennifer Payandeh, Barbara Mcgillivray, Graeme Mccauley, John R. Swiston, Pearce Wilcox, Anna LehmanAbstract:Introduction Tracheobronchomegaly (Mounier-Kuhn Syndrome) is a rare disease characterized by tracheal enlargement and associated loss of elastic fibers in the trachea and main bronchi. Materials MEDLINE, Index Medicus, and other databases were searched with pre-defined criteria to identify cases of Tracheobronchomegaly (TBM). Two new cases of TBM were also identified from the Provincial Medical Genetics Program of British Columbia. Results We identified 166 publications describing 365 occurrences of TBM. We observed that affected individuals could be grouped into subgroups according to clinical features. Type 1A (105 individuals) consists of infants who developed TBM after having undergone fetoscopic tracheal occlusion, and Type 1B patients (24 individuals) are infants and children who developed TBM after prolonged intubation. Type 2 individuals developed TBM following recurrent pulmonary infections (2A) (14 individuals) or pulmonary fibrosis (2B) (10 individuals). Type 3 represents TBM with evidence of extra-pulmonary elastolysis (18 individuals), and Type 4 denotes the development of TBM with no clear predisposing factors (196 individuals). Both of our patients had TBM and evidence of extra-pulmonary elastolysis. As well, one patient had a mildly dilated aortic root, which is a previously unreported co-occurrence. Conclusion We introduce a novel classification scheme, which may sort patients into etiologically distinct groups, furthering our understanding of its pathogenesis and potentially, prevention or therapy. We also hypothesize that TBM and generalized elastolysis may have etiological commonalities, suggesting a need for further study.
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A Clinical Classification Scheme for Tracheobronchomegaly (Mounier-Kuhn Syndrome)
Lung, 2015Co-Authors: Jennifer Payandeh, Barbara Mcgillivray, Graeme Mccauley, Pearce G. Wilcox, John R. Swiston, Anna LehmanAbstract:Introduction Tracheobronchomegaly (Mounier-Kuhn Syndrome) is a rare disease characterized by tracheal enlargement and associated loss of elastic fibers in the trachea and main bronchi.
Jirat Chenbhanich - One of the best experts on this subject based on the ideXlab platform.
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A case of Tracheobronchomegaly
European journal of internal medicine, 2017Co-Authors: Jirat Chenbhanich, Juan Villa-camacho, Jason M. KonterAbstract:Tracheobronchomegaly (Mounier-Kuhn syndrome) is a rare condition characterized by an abnormally enlarged trachea and main bronchi. Herein, we present a case of 79-year-old male with idiopathic pulmonary fibrosis and acute hypoxemic respiratory failure due to multilobar pneumonia. Computed tomography of the chest demonstrated a markedly dilated trachea, with the transverse diameter of 31mm and the sagittal diameter of 30mm. The clinical manifestations as well as its diagnosis, classification, and treatment are discussed.
Jennifer Payandeh - One of the best experts on this subject based on the ideXlab platform.
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A Clinical Classification Scheme for Tracheobronchomegaly (Mounier-Kuhn Syndrome)
Lung, 2015Co-Authors: Jennifer Payandeh, Barbara Mcgillivray, Graeme Mccauley, John R. Swiston, Pearce Wilcox, Anna LehmanAbstract:Introduction Tracheobronchomegaly (Mounier-Kuhn Syndrome) is a rare disease characterized by tracheal enlargement and associated loss of elastic fibers in the trachea and main bronchi. Materials MEDLINE, Index Medicus, and other databases were searched with pre-defined criteria to identify cases of Tracheobronchomegaly (TBM). Two new cases of TBM were also identified from the Provincial Medical Genetics Program of British Columbia. Results We identified 166 publications describing 365 occurrences of TBM. We observed that affected individuals could be grouped into subgroups according to clinical features. Type 1A (105 individuals) consists of infants who developed TBM after having undergone fetoscopic tracheal occlusion, and Type 1B patients (24 individuals) are infants and children who developed TBM after prolonged intubation. Type 2 individuals developed TBM following recurrent pulmonary infections (2A) (14 individuals) or pulmonary fibrosis (2B) (10 individuals). Type 3 represents TBM with evidence of extra-pulmonary elastolysis (18 individuals), and Type 4 denotes the development of TBM with no clear predisposing factors (196 individuals). Both of our patients had TBM and evidence of extra-pulmonary elastolysis. As well, one patient had a mildly dilated aortic root, which is a previously unreported co-occurrence. Conclusion We introduce a novel classification scheme, which may sort patients into etiologically distinct groups, furthering our understanding of its pathogenesis and potentially, prevention or therapy. We also hypothesize that TBM and generalized elastolysis may have etiological commonalities, suggesting a need for further study.
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A Clinical Classification Scheme for Tracheobronchomegaly (Mounier-Kuhn Syndrome)
Lung, 2015Co-Authors: Jennifer Payandeh, Barbara Mcgillivray, Graeme Mccauley, Pearce G. Wilcox, John R. Swiston, Anna LehmanAbstract:Introduction Tracheobronchomegaly (Mounier-Kuhn Syndrome) is a rare disease characterized by tracheal enlargement and associated loss of elastic fibers in the trachea and main bronchi.
L Rossoff - One of the best experts on this subject based on the ideXlab platform.
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Tracheobronchomegaly.
Chest, 1994Co-Authors: M Schwartz, L RossoffAbstract:We report two cases of Tracheobronchomegaly with differing presentations. The radiologic, fiberoptic bronchoscopic, and clinical findings as well as management of this rare condition are reviewed.