The Experts below are selected from a list of 216 Experts worldwide ranked by ideXlab platform

Morton E Smith - One of the best experts on this subject based on the ideXlab platform.

  • late onset rhegmatogenous Traction Retinal Detachment due to candida chorioretinitis reply
    Archives of Ophthalmology, 1993
    Co-Authors: Samuel R Pesin, Matthew A Thomas, Morton E Smith
    Abstract:

    In Reply. —We appreciate the comments of Lightman et al regarding our clinical case report. As for the choice of antifungal treatment without concurrent intracameral therapy, we were not involved in the patient's initial treatment. In October 1989, he presented to an outside hospital with systemic signs of candidemia. At that time, according to the referring physician, the patient had diffuse conjunctival hyperemia, posterior synechiae, and anterior and posterior uveitis, giving a limited view of the retina. He was treated with intravenous amphotericin B and topical drops, and the candidemia resolved after 1 month of therapy. When we evaluated the patient's condition in February 1990, his eye examination revealed clear conjunctiva, no evidence of anterior chamber or vitreous inflammatory cells, resolved synechiae, and a clear view of the fundus. Thus, while Lightman et al point out that intravenous amphotericin B may have poor ocular penetration, our case resembles numerous others

  • combined rhegmatogenous Traction Retinal Detachment following successful treatment of candida chorioretinitis
    Archives of Ophthalmology, 1992
    Co-Authors: Samuel R Pesin, Matthew A Thomas, Morton E Smith
    Abstract:

    In spite of successful treatment with amphotericin B, eyes withCandidaendophthalmitis remain at high risk for profound visual loss from such complications as subRetinal neovascular membranes, macular pucker, or Traction macular Detachments.1-4We describe a patient with a rhegmatogenous Retinal Detachment associated with a Traction macular Detachment in an eye that had otherwise been successfully treated forCandidaendophthalmitis. To our knowledge, such a complication has not been previously reported after resolution of activeCandidachorioretinitis. Report of a Case. —A 55-year-old man was referred for a Retinal Detachment in his right eye. In July 1989, a non-oat-cell carcinoma of the lung without metastases had been diagnosed at another hospital. Following treatment with radiation and cisplatin the patient developed neutropenia and culture-proved candidemia in October 1989. Concurrently, visual acuity in his right eye decreased from 20/50 to 20/400. The conjunctiva had been hyperemic, and posterior synechiae prevented adequate

Carol L. Shields - One of the best experts on this subject based on the ideXlab platform.

  • Spontaneous Regression of Florid Retinal Neovascularization Following Resolution of Traction Retinal Detachment in an Eye With Treated Retinoblastoma.
    Journal of pediatric ophthalmology and strabismus, 2019
    Co-Authors: Kalla A Gervasio, Lauren A Dalvin, Carol L. Shields
    Abstract:

    A 19-month-old boy with unilateral retinoblastoma with iris and Retinal neovascularization at initial presentation displayed Traction Retinal Detachment, Retinal non-perfusion, and persistent Retinal neovascularization after completion of intra-arterial chemotherapy. Two months following resolution of Traction Retinal Detachment, restoration of Retinal perfusion and regression of neovascularization occurred without additional intervention. Spontaneous regression of Retinal neovascularization is possible following resolution of Traction Retinal Detachment. [J Pediatr Ophthalmol Strabismus. 2019;56:e24-e27.].

  • Incontinentia pigmenti in a child with suspected retinoblastoma
    BMC, 2017
    Co-Authors: Stephanie J. Weiss, Archana Srinivasan, Michael A. Klufas, Carol L. Shields
    Abstract:

    Abstract Background Incontinentia pigmenti is a rare X-linked dominant syndrome caused by mutation in the NEMO/IKKgamma gene, and characterized by a spectrum of cutaneous, ocular, neurologic and dental abnormalities. In the eye, findings include Retinal vascular non-perfusion, occasionally with Traction Retinal Detachment, Retinal fibrosis, and Retinal pigment epithelium defects. These findings can resemble retinoblastoma, especially when vitreoRetinal fibrosis produces leukocoria. Case report A 2-month-old girl born full-term presented with leukocoria, suspicious for retinoblastoma. She was found to have an ischemic retrolental fibrovascular Retinal Detachment. In addition, there was linear cutaneous hyperpigmentation, diagnostic of incontinentia pigmenti. Conclusions Retinoblastoma can be a challenge to diagnose. There are numerous simulating lesions that can present with leukocoria and Retinal Detachment, including incontinentia pigmenti. Recognition of the cutaneous features of incontinentia pigmenti contributes to early detection of related ophthalmologic, neurologic and dental abnormalities

  • bevacizumab for coats disease with exudative Retinal Detachment and risk of vitreoRetinal Traction
    British Journal of Ophthalmology, 2012
    Co-Authors: Aparna Ramasubramanian, Carol L. Shields
    Abstract:

    AIM: To evaluate the effect of supplemental intravitreal bevacizumab for management of Coats' disease. METHODS: Retrospective analysis of eight patients with Coats' disease manifesting total or partial exudative Retinal Detachment where the Retinal telangiectasia was treated with standard laser photocoagulation and/or cryotherapy plus additional intravitreal bevacizumab (1.25 mg/0.05 ml). RESULTS: The mean patient age was 88 (range 7-240) months and 63% were male. Coats' disease was classified as stage 2 (n=1, 12%), 3a (n=3, 38%) and 3b (n=4, 50%). Features included Retinal Detachment (n=8, 100% with mean Detachment extent involving 8 clock hours), telangiectasia (n=8, 100% with mean extent of 8 clock hours), peripheral Retinal ischaemia on fluorescein angiography (n=7, 88%) and no evidence of neovascularisation. Treatment consisted of cryotherapy (n=8, 100%), laser photocoagulation (n=4, 50%) and bevacizumab intravitreal injection (n=8) with median number of one injection per eye (mean 1.75, and range 1-4 injections). After a mean follow-up of 8.5 months, resolution of retinopathy (n=8, 100%), Coats'-related subRetinal fluid (n=8, 100%) and Retinal exudation (n=6, 75%) was noted. However, vitreous fibrosis developed (n=4, 50%) at a mean of 5 months following a mean of 1.75 bevacizumab injections with three (38%) evolving into Traction Retinal Detachment. CONCLUSION: Coats' disease treated with intravitreal bevacizumab in addition to standard therapy can develop to vitreoRetinal fibrosis and potentially Traction Retinal Detachment. These Tractional features are not often found in Coats' disease treated with standard measures without bevacizumab. Caution is advised in the use of bevacizumab for patients with Coats' disease.

Samuel R Pesin - One of the best experts on this subject based on the ideXlab platform.

  • late onset rhegmatogenous Traction Retinal Detachment due to candida chorioretinitis reply
    Archives of Ophthalmology, 1993
    Co-Authors: Samuel R Pesin, Matthew A Thomas, Morton E Smith
    Abstract:

    In Reply. —We appreciate the comments of Lightman et al regarding our clinical case report. As for the choice of antifungal treatment without concurrent intracameral therapy, we were not involved in the patient's initial treatment. In October 1989, he presented to an outside hospital with systemic signs of candidemia. At that time, according to the referring physician, the patient had diffuse conjunctival hyperemia, posterior synechiae, and anterior and posterior uveitis, giving a limited view of the retina. He was treated with intravenous amphotericin B and topical drops, and the candidemia resolved after 1 month of therapy. When we evaluated the patient's condition in February 1990, his eye examination revealed clear conjunctiva, no evidence of anterior chamber or vitreous inflammatory cells, resolved synechiae, and a clear view of the fundus. Thus, while Lightman et al point out that intravenous amphotericin B may have poor ocular penetration, our case resembles numerous others

  • combined rhegmatogenous Traction Retinal Detachment following successful treatment of candida chorioretinitis
    Archives of Ophthalmology, 1992
    Co-Authors: Samuel R Pesin, Matthew A Thomas, Morton E Smith
    Abstract:

    In spite of successful treatment with amphotericin B, eyes withCandidaendophthalmitis remain at high risk for profound visual loss from such complications as subRetinal neovascular membranes, macular pucker, or Traction macular Detachments.1-4We describe a patient with a rhegmatogenous Retinal Detachment associated with a Traction macular Detachment in an eye that had otherwise been successfully treated forCandidaendophthalmitis. To our knowledge, such a complication has not been previously reported after resolution of activeCandidachorioretinitis. Report of a Case. —A 55-year-old man was referred for a Retinal Detachment in his right eye. In July 1989, a non-oat-cell carcinoma of the lung without metastases had been diagnosed at another hospital. Following treatment with radiation and cisplatin the patient developed neutropenia and culture-proved candidemia in October 1989. Concurrently, visual acuity in his right eye decreased from 20/50 to 20/400. The conjunctiva had been hyperemic, and posterior synechiae prevented adequate

William Tasman - One of the best experts on this subject based on the ideXlab platform.

  • Familial exudative vitreoretinopathy: surgical intervention and visual acuity outcomes
    Graefe's Archive for Clinical and Experimental Ophthalmology, 1997
    Co-Authors: Allan Shubert, William Tasman
    Abstract:

    • Background: Familial exudative vitreoretinopathy (FEVR) is a hereditary condition that may lead to vitreous hemorrhage and Traction Retinal Detachment necessitating surgical intervention. In this paper we review the results of surgery on seven such patients (eight eyes). • Methods: Seven patients (eight eyes) were followed up after surgery that had been performed because of vitreous hemorrhage and/or Traction Retinal Detachment due to FEVR, in an effort to evaluate outcomes. Parameters that were noted were the current age, gender, age at the time of first surgery, length of follow-up and postoperative Retinal status and visual acuity. • Results: Seven patients (eight eyes) ranging in age from 6 months to 44 years with a mean of 24.7 and a median of 26 years were followed. There were three females and four males. The lowest age at which surgery was first performed was 6 months and the highest was 28 years, with a mean of 14.7 and a median of 17 years. Six of the 8 eyes were reattached following surgery, although some required multiple procedures. • Conclusion: VitreoRetinal surgery may be of benefit in helping to preserve some degree of vision in eyes of patients with FEVR who develop vitreous hemorrhage and/or Retinal Detachment.

Matthew A Thomas - One of the best experts on this subject based on the ideXlab platform.

  • late onset rhegmatogenous Traction Retinal Detachment due to candida chorioretinitis reply
    Archives of Ophthalmology, 1993
    Co-Authors: Samuel R Pesin, Matthew A Thomas, Morton E Smith
    Abstract:

    In Reply. —We appreciate the comments of Lightman et al regarding our clinical case report. As for the choice of antifungal treatment without concurrent intracameral therapy, we were not involved in the patient's initial treatment. In October 1989, he presented to an outside hospital with systemic signs of candidemia. At that time, according to the referring physician, the patient had diffuse conjunctival hyperemia, posterior synechiae, and anterior and posterior uveitis, giving a limited view of the retina. He was treated with intravenous amphotericin B and topical drops, and the candidemia resolved after 1 month of therapy. When we evaluated the patient's condition in February 1990, his eye examination revealed clear conjunctiva, no evidence of anterior chamber or vitreous inflammatory cells, resolved synechiae, and a clear view of the fundus. Thus, while Lightman et al point out that intravenous amphotericin B may have poor ocular penetration, our case resembles numerous others

  • combined rhegmatogenous Traction Retinal Detachment following successful treatment of candida chorioretinitis
    Archives of Ophthalmology, 1992
    Co-Authors: Samuel R Pesin, Matthew A Thomas, Morton E Smith
    Abstract:

    In spite of successful treatment with amphotericin B, eyes withCandidaendophthalmitis remain at high risk for profound visual loss from such complications as subRetinal neovascular membranes, macular pucker, or Traction macular Detachments.1-4We describe a patient with a rhegmatogenous Retinal Detachment associated with a Traction macular Detachment in an eye that had otherwise been successfully treated forCandidaendophthalmitis. To our knowledge, such a complication has not been previously reported after resolution of activeCandidachorioretinitis. Report of a Case. —A 55-year-old man was referred for a Retinal Detachment in his right eye. In July 1989, a non-oat-cell carcinoma of the lung without metastases had been diagnosed at another hospital. Following treatment with radiation and cisplatin the patient developed neutropenia and culture-proved candidemia in October 1989. Concurrently, visual acuity in his right eye decreased from 20/50 to 20/400. The conjunctiva had been hyperemic, and posterior synechiae prevented adequate