The Experts below are selected from a list of 57 Experts worldwide ranked by ideXlab platform
Viji Sundaram - One of the best experts on this subject based on the ideXlab platform.
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Fertility Preservation for the Transgender Individual
Current Obstetrics and Gynecology Reports, 2020Co-Authors: Viji SundaramAbstract:Purpose of Review This review aims to update readers on recent evidence in order to counsel and guide clinical management of Individuals with gender dysphoria seeking fertility preservation (FP). Recent Findings Relevant topics include a discussion of the consistent desire for children in Transgender people despite a low utilization rate of FP services, animal models, and human histology depicting the effect of gender-affirming treatment (GAT) on the gonads, varied time for resumption of menses, and start of ovarian stimulation upon discontinuing testosterone (T) in transmen, feasible clinical and experimental options for FP in Transgender males and females, worsening dysphoria, and recommended methods to mitigate symptoms, and lastly a short discussion of changes in legislation providing increased insurance coverage of medically indicated FP for transpatients. Summary FP is an important option for Transgender patients who desire to retain the ability to become genetic parents. While controlled ovarian stimulation for oocyte or embryo cryopreservation is the standard-of-care for transmen, unique considerations must be made in this population. Recent literature has highlighted the ability of transmen to have viable oocytes and pregnancies despite a history of T use, suggesting that the window of genetic parentage does not close with the start of GAT. FP for transwomen requires ejaculation or extraction with sperm cryopreservation; options for prepubertal transwomen are only in nascent phases. Research is rapidly evolving though many questions remain unanswered. The harmonization of advances in assisted reproduction with legislation advocating for Transgender rights will continue to reach new peaks in the coming years.
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fertility preservation for the Transgender Individual
Current Obstetrics and Gynecology Reports, 2020Co-Authors: Viji Sundaram, E MoklinAbstract:This review aims to update readers on recent evidence in order to counsel and guide clinical management of Individuals with gender dysphoria seeking fertility preservation (FP). Relevant topics include a discussion of the consistent desire for children in Transgender people despite a low utilization rate of FP services, animal models, and human histology depicting the effect of gender-affirming treatment (GAT) on the gonads, varied time for resumption of menses, and start of ovarian stimulation upon discontinuing testosterone (T) in transmen, feasible clinical and experimental options for FP in Transgender males and females, worsening dysphoria, and recommended methods to mitigate symptoms, and lastly a short discussion of changes in legislation providing increased insurance coverage of medically indicated FP for transpatients. FP is an important option for Transgender patients who desire to retain the ability to become genetic parents. While controlled ovarian stimulation for oocyte or embryo cryopreservation is the standard-of-care for transmen, unique considerations must be made in this population. Recent literature has highlighted the ability of transmen to have viable oocytes and pregnancies despite a history of T use, suggesting that the window of genetic parentage does not close with the start of GAT. FP for transwomen requires ejaculation or extraction with sperm cryopreservation; options for prepubertal transwomen are only in nascent phases. Research is rapidly evolving though many questions remain unanswered. The harmonization of advances in assisted reproduction with legislation advocating for Transgender rights will continue to reach new peaks in the coming years.
Zaraq Khan - One of the best experts on this subject based on the ideXlab platform.
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Fertility Preservation for Transgender Individuals: A Review.
Mayo Clinic proceedings, 2020Co-Authors: Alessandra J. Ainsworth, Megan Allyse, Zaraq KhanAbstract:Abstract Transgender Individuals represent a small, albeit growing, patient population that is encountered more frequently in clinical care due to improved insurance coverage and increasing awareness. Gender-affirming treatments, including both gender-affirming hormone therapy and gender-affirming surgery, pose significant risks to fertility potential and outcomes, ranging from potentially impaired fertility rates to full elimination of reproductive potential depending on the type of treatment pursued. However, there are relatively limited data specific to fertility preservation for Transgender Individuals. Current approaches to treatment are extrapolated from options for fertility preservation after oncologic diagnoses. In this review, we aim to summarize current clinical approaches, fertility preservation options, and patient experiences in fertility preservation for Transgender Individuals. Several forms of fertility preservation options are available depending on the pubertal status of a Transgender Individual. Despite the multiple options for fertility preservation, major barriers exist to patient care and there are reports of mixed patient experiences. Further awareness of this clinical situation and understanding of these processes will allow for comprehensive and specialized care for Transgender Individuals who may otherwise miss opportunities for adequate counseling or treatment options regarding fertility preservation.
E Moklin - One of the best experts on this subject based on the ideXlab platform.
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fertility preservation for the Transgender Individual
Current Obstetrics and Gynecology Reports, 2020Co-Authors: Viji Sundaram, E MoklinAbstract:This review aims to update readers on recent evidence in order to counsel and guide clinical management of Individuals with gender dysphoria seeking fertility preservation (FP). Relevant topics include a discussion of the consistent desire for children in Transgender people despite a low utilization rate of FP services, animal models, and human histology depicting the effect of gender-affirming treatment (GAT) on the gonads, varied time for resumption of menses, and start of ovarian stimulation upon discontinuing testosterone (T) in transmen, feasible clinical and experimental options for FP in Transgender males and females, worsening dysphoria, and recommended methods to mitigate symptoms, and lastly a short discussion of changes in legislation providing increased insurance coverage of medically indicated FP for transpatients. FP is an important option for Transgender patients who desire to retain the ability to become genetic parents. While controlled ovarian stimulation for oocyte or embryo cryopreservation is the standard-of-care for transmen, unique considerations must be made in this population. Recent literature has highlighted the ability of transmen to have viable oocytes and pregnancies despite a history of T use, suggesting that the window of genetic parentage does not close with the start of GAT. FP for transwomen requires ejaculation or extraction with sperm cryopreservation; options for prepubertal transwomen are only in nascent phases. Research is rapidly evolving though many questions remain unanswered. The harmonization of advances in assisted reproduction with legislation advocating for Transgender rights will continue to reach new peaks in the coming years.
Alessandra J. Ainsworth - One of the best experts on this subject based on the ideXlab platform.
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Fertility Preservation for Transgender Individuals: A Review.
Mayo Clinic proceedings, 2020Co-Authors: Alessandra J. Ainsworth, Megan Allyse, Zaraq KhanAbstract:Abstract Transgender Individuals represent a small, albeit growing, patient population that is encountered more frequently in clinical care due to improved insurance coverage and increasing awareness. Gender-affirming treatments, including both gender-affirming hormone therapy and gender-affirming surgery, pose significant risks to fertility potential and outcomes, ranging from potentially impaired fertility rates to full elimination of reproductive potential depending on the type of treatment pursued. However, there are relatively limited data specific to fertility preservation for Transgender Individuals. Current approaches to treatment are extrapolated from options for fertility preservation after oncologic diagnoses. In this review, we aim to summarize current clinical approaches, fertility preservation options, and patient experiences in fertility preservation for Transgender Individuals. Several forms of fertility preservation options are available depending on the pubertal status of a Transgender Individual. Despite the multiple options for fertility preservation, major barriers exist to patient care and there are reports of mixed patient experiences. Further awareness of this clinical situation and understanding of these processes will allow for comprehensive and specialized care for Transgender Individuals who may otherwise miss opportunities for adequate counseling or treatment options regarding fertility preservation.
M Nelson - One of the best experts on this subject based on the ideXlab platform.
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Knowledge and sexual behaviors of Transgender Individuals faced with the risk of STI/HIV in Benin
European Journal of Public Health, 2019Co-Authors: Septime Hessou, Y Glele Ahanhanzo, Alphonse Kpozehouen, Alphonse Biaou, T Yadouleton, Odile Sodoloufo, Virgile Capo-chichi, B Dossoh, B Gnanhoui-david, M NelsonAbstract:Abstract Introduction The issue of sexually transmitted infections (STIs) and Human Immunodeficiency Virus (HIV)/Acquired Immune Deficiency Syndrome (AIDS) cannot be solved without considering the Transgender population. This research aims to describe the knowledge, attitudes and sexual behaviors of Transgender Individuals faced with the risk of STIs and HIV/AIDS in Benin. Methods Transgender Individuals were selected by respondent-driven sampling throughout the country in 2017. Included in this analysis were Individuals who identified as Transgender and adopted its mode of expression, aged 15 years and greater, and who gave their consent to participate. Results A total of 308 Transgender Individuals were surveyed, of which 89.6% were of male gender at birth. The participants had a good level of knowledge in the matter of STI and HIV/AIDS. In fact, 99.9% among them cited at least one symptom of STIs; 95.1% cited the three main methods of transmission of HIV and 54% are aware the risk of sexual transmission of HIV is higher between men. Participants were more than 90% likely to declare a positive attitude to care for persons living with HIV (PLWHIV) or to share the same room with them (93.2%). Concerning sexual behaviors, the average age at the first sexual encounter as a Transgender Individual was 14 years old. During the last three months, Transgender Individuals declared three regular male partners on average. The usage of condoms during the last sexual intercourse was reported in 86.6% of cases. Knowledge of the serological status of the sexual partner (31.7%) and the loss of sensation induced by the condom (26.8%) constituted the main reasons of non-usage of condoms. Conclusions Although adopting some risky sexual behavior, Transgender Individuals are a population that is relatively well informed and with favorable attitudes regarding STIs and HIV/AIDS. These factors are significant assets to be considered in the development of programs for STIs and HIV/AIDS control. Key messages Transgender Individuals good level of knowledge is an asset for STIs/HIV control. Sexual multi-partnership seems to be common despite a good level of knowledge.