The Experts below are selected from a list of 45 Experts worldwide ranked by ideXlab platform

Napier J. A. - One of the best experts on this subject based on the ideXlab platform.

  • Delta 6-desaturases From Primulaceae, Expressing Plants And Pufa-containing Oils (Patent CA 2476041 C)
    2013
    Co-Authors: Napier J. A., Sayanova O.
    Abstract:

    The present invention relates to an improved method for the specific production of unsaturated .omega.-3 fatty acids and a method for the production of triglycerides having an increased content of unsaturated fatty acids, in particular .omega.-3 fatty acids having more than three double bonds. The invention relates to the production of a Transgenic organism, preferably a Transgenic plant or a Transgenic Microorganism, having an increased content of fatty acids, oils or lipids having .DELTA. 6 double bonds due to the expression of a .DELTA. 6-desaturase from Primulaceae. The invention additionally relates to expression cassettes containing a nucleic acid sequence, a vector and organisms containing at least one nucleic acid sequence or an expression cassette. The invention further relates to unsaturated fatty acids and triglycerides having an increased content of unsaturated fatty acids and use thereof

  • Delta 6 Desaturases From Primulaceae, Expressing Plants And Pufa-containing Oils (Patent US 8329993 B2)
    2012
    Co-Authors: Napier J. A., Sayanova O.
    Abstract:

    The present invention relates to an improved method for the specific production of unsaturated ω-3 fatty acids and a method for the production of triglycerides having an increased content of unsaturated fatty acids, in particular ω-3 fatty acids having more than three double bonds. The invention relates to the production of a Transgenic organism, preferably a Transgenic plant or a Transgenic Microorganism, having an increased content of fatty acids, oils or lipids having Δ6 double bonds due to the expression of a Δ6-desaturase from Primulaceae. The invention additionally relates to expression cassettes containing a nucleic acid sequence, a vector and organisms containing at least one nucleic acid sequence or an expression cassette. The invention further relates to unsaturated fatty acids and triglycerides having an increased content of unsaturated fatty acids and use thereof

  • Delta6-desaturases From Primulaceae, Expressing Plants And Pufa-containing Oils (Patent US 7554008 B2)
    2009
    Co-Authors: Napier J. A., Sayanova O.
    Abstract:

    The present invention relates to an improved method for the specific production of unsaturated omega-3 fatty acids and a method for the production of triglycerides having an increased content of unsaturated fatty acids, in particular omega-3 fatty acids having more than three double bonds. The invention relates to the production of a Transgenic organism, preferably a Transgenic plant or a Transgenic Microorganism, having an increased content of fatty acids, oils or lipids having Delta6 double bonds due to the expression of a Delta6-desaturase from Primulaceae. The invention additionally relates to expression cassettes containing a nucleic acid sequence, a vector and organisms containing at least one nucleic acid sequence or an expression cassette. The invention further relates to unsaturated fatty acids and triglycerides having an increased content of unsaturated fatty acids and use thereof

  • Delta 6-desaturases From Primulaceae, Expressing Plants And Pufa-containing Oils (Patent EP 1726652 A2)
    2006
    Co-Authors: Napier J. A., Sayanova O.
    Abstract:

    The present invention relates to an improved method for the specific production of unsaturated É-3 fatty acids and a method for the production of triglycerides having an increased content of unsaturated fatty acids, in particular É-3 fatty acids having more than three double bonds. The invention relates to the production of a Transgenic organism, preferably a Transgenic plant or a Transgenic Microorganism, having an increased content of fatty acids, oils or lipids having ” 6 double bonds due to the expression of a A 6-desaturase from Primulaceae. The invention additionally relates to expression cassettes containing a nucleic acid sequence, a vector and organisms containing at least one nucleic acid sequence or an expression cassette. The invention further relates to unsaturated fatty acids and triglycerides having an increased content of unsaturated fatty acids and use thereof

  • Novel Method For The Production Of Polyunsaturated Fatty Acids (Patent US 2006/0246556 A1)
    2006
    Co-Authors: Napier J. A., Sayanova O., Lazarus C., Qi B., Heinz E., Zank T., Zahringer U.
    Abstract:

    The present invention relates to an improved process for the specific production of poly-unsaturated omega-3 and omega-6 fatty acids and a process for the production of triglycerides having an increased content of unsaturated fatty acids, in particular omega-3 and omega-6 fatty acids having at least two double bonds and a 20 or 22 carbon atom chain length. The invention relates to the production of a Transgenic organism, preferably a Transgenic plant or a Transgenic Microorganism, hav-ing an increased content of fatty acids, oils or lipids containing C20- or C22-fatty acids with a delta-5, 7, 8, 10 double bond, respectively due to the expression of a delta-8-desaturase and a delta-9-elon-gase from organisms such as plants preferably Algae like Isochrysis galbana or Euglena gracilis. In addition the invention relates to a process for the production of poly unsaturated fatty acids such as Eicosapentaenoic, Arachidonic, Docosapentaenoic or Doosahexaenoic acid through the co-expression of a delta-8-desaturase, a delta-9-elongase and a delta-5 desaturase in organisms such as Microorganisms or plants. The invention additionally relates to the use of specific nucleic acid sequences encoding for the aforementioned proteins with delta-8-desaturase-, delta-9-elongase- or delta-5-desaturase-activity, nucleic acid constructs, vectors and organisms containing said nucleic acid sequences. The invention further relates to unsaturated fatty acids and triglycerides having an increased content of at least 1% by weight of unsaturated fatty acids and use thereof

Sayanova O. - One of the best experts on this subject based on the ideXlab platform.

  • Delta 6-desaturases From Primulaceae, Expressing Plants And Pufa-containing Oils (Patent CA 2476041 C)
    2013
    Co-Authors: Napier J. A., Sayanova O.
    Abstract:

    The present invention relates to an improved method for the specific production of unsaturated .omega.-3 fatty acids and a method for the production of triglycerides having an increased content of unsaturated fatty acids, in particular .omega.-3 fatty acids having more than three double bonds. The invention relates to the production of a Transgenic organism, preferably a Transgenic plant or a Transgenic Microorganism, having an increased content of fatty acids, oils or lipids having .DELTA. 6 double bonds due to the expression of a .DELTA. 6-desaturase from Primulaceae. The invention additionally relates to expression cassettes containing a nucleic acid sequence, a vector and organisms containing at least one nucleic acid sequence or an expression cassette. The invention further relates to unsaturated fatty acids and triglycerides having an increased content of unsaturated fatty acids and use thereof

  • Delta 6 Desaturases From Primulaceae, Expressing Plants And Pufa-containing Oils (Patent US 8329993 B2)
    2012
    Co-Authors: Napier J. A., Sayanova O.
    Abstract:

    The present invention relates to an improved method for the specific production of unsaturated ω-3 fatty acids and a method for the production of triglycerides having an increased content of unsaturated fatty acids, in particular ω-3 fatty acids having more than three double bonds. The invention relates to the production of a Transgenic organism, preferably a Transgenic plant or a Transgenic Microorganism, having an increased content of fatty acids, oils or lipids having Δ6 double bonds due to the expression of a Δ6-desaturase from Primulaceae. The invention additionally relates to expression cassettes containing a nucleic acid sequence, a vector and organisms containing at least one nucleic acid sequence or an expression cassette. The invention further relates to unsaturated fatty acids and triglycerides having an increased content of unsaturated fatty acids and use thereof

  • Delta6-desaturases From Primulaceae, Expressing Plants And Pufa-containing Oils (Patent US 7554008 B2)
    2009
    Co-Authors: Napier J. A., Sayanova O.
    Abstract:

    The present invention relates to an improved method for the specific production of unsaturated omega-3 fatty acids and a method for the production of triglycerides having an increased content of unsaturated fatty acids, in particular omega-3 fatty acids having more than three double bonds. The invention relates to the production of a Transgenic organism, preferably a Transgenic plant or a Transgenic Microorganism, having an increased content of fatty acids, oils or lipids having Delta6 double bonds due to the expression of a Delta6-desaturase from Primulaceae. The invention additionally relates to expression cassettes containing a nucleic acid sequence, a vector and organisms containing at least one nucleic acid sequence or an expression cassette. The invention further relates to unsaturated fatty acids and triglycerides having an increased content of unsaturated fatty acids and use thereof

  • Delta 6-desaturases From Primulaceae, Expressing Plants And Pufa-containing Oils (Patent EP 1726652 A2)
    2006
    Co-Authors: Napier J. A., Sayanova O.
    Abstract:

    The present invention relates to an improved method for the specific production of unsaturated É-3 fatty acids and a method for the production of triglycerides having an increased content of unsaturated fatty acids, in particular É-3 fatty acids having more than three double bonds. The invention relates to the production of a Transgenic organism, preferably a Transgenic plant or a Transgenic Microorganism, having an increased content of fatty acids, oils or lipids having ” 6 double bonds due to the expression of a A 6-desaturase from Primulaceae. The invention additionally relates to expression cassettes containing a nucleic acid sequence, a vector and organisms containing at least one nucleic acid sequence or an expression cassette. The invention further relates to unsaturated fatty acids and triglycerides having an increased content of unsaturated fatty acids and use thereof

  • Novel Method For The Production Of Polyunsaturated Fatty Acids (Patent US 2006/0246556 A1)
    2006
    Co-Authors: Napier J. A., Sayanova O., Lazarus C., Qi B., Heinz E., Zank T., Zahringer U.
    Abstract:

    The present invention relates to an improved process for the specific production of poly-unsaturated omega-3 and omega-6 fatty acids and a process for the production of triglycerides having an increased content of unsaturated fatty acids, in particular omega-3 and omega-6 fatty acids having at least two double bonds and a 20 or 22 carbon atom chain length. The invention relates to the production of a Transgenic organism, preferably a Transgenic plant or a Transgenic Microorganism, hav-ing an increased content of fatty acids, oils or lipids containing C20- or C22-fatty acids with a delta-5, 7, 8, 10 double bond, respectively due to the expression of a delta-8-desaturase and a delta-9-elon-gase from organisms such as plants preferably Algae like Isochrysis galbana or Euglena gracilis. In addition the invention relates to a process for the production of poly unsaturated fatty acids such as Eicosapentaenoic, Arachidonic, Docosapentaenoic or Doosahexaenoic acid through the co-expression of a delta-8-desaturase, a delta-9-elongase and a delta-5 desaturase in organisms such as Microorganisms or plants. The invention additionally relates to the use of specific nucleic acid sequences encoding for the aforementioned proteins with delta-8-desaturase-, delta-9-elongase- or delta-5-desaturase-activity, nucleic acid constructs, vectors and organisms containing said nucleic acid sequences. The invention further relates to unsaturated fatty acids and triglycerides having an increased content of at least 1% by weight of unsaturated fatty acids and use thereof

Zank T. - One of the best experts on this subject based on the ideXlab platform.

  • Novel Method For The Production Of Polyunsaturated Fatty Acids (Patent US 2006/0246556 A1)
    2006
    Co-Authors: Napier J. A., Sayanova O., Lazarus C., Qi B., Heinz E., Zank T., Zahringer U.
    Abstract:

    The present invention relates to an improved process for the specific production of poly-unsaturated omega-3 and omega-6 fatty acids and a process for the production of triglycerides having an increased content of unsaturated fatty acids, in particular omega-3 and omega-6 fatty acids having at least two double bonds and a 20 or 22 carbon atom chain length. The invention relates to the production of a Transgenic organism, preferably a Transgenic plant or a Transgenic Microorganism, hav-ing an increased content of fatty acids, oils or lipids containing C20- or C22-fatty acids with a delta-5, 7, 8, 10 double bond, respectively due to the expression of a delta-8-desaturase and a delta-9-elon-gase from organisms such as plants preferably Algae like Isochrysis galbana or Euglena gracilis. In addition the invention relates to a process for the production of poly unsaturated fatty acids such as Eicosapentaenoic, Arachidonic, Docosapentaenoic or Doosahexaenoic acid through the co-expression of a delta-8-desaturase, a delta-9-elongase and a delta-5 desaturase in organisms such as Microorganisms or plants. The invention additionally relates to the use of specific nucleic acid sequences encoding for the aforementioned proteins with delta-8-desaturase-, delta-9-elongase- or delta-5-desaturase-activity, nucleic acid constructs, vectors and organisms containing said nucleic acid sequences. The invention further relates to unsaturated fatty acids and triglycerides having an increased content of at least 1% by weight of unsaturated fatty acids and use thereof

  • Method For The Production Of Polyunsaturated Fatty Acids (Patent CA 2510462 A1)
    2004
    Co-Authors: Heinz E., Napier J. A., Sayanova O., Qi B., Zahringer U., Lazarus C. M., Zank T.
    Abstract:

    The present invention relates to an improved process for the specific production of poly-unsaturated omega-3 and omega-6 fatty acids and a process for the production of triglycerides having an increased content of unsaturat ed fatty acids, in particular omega-3 and omega-6 fatty acids having at least t wo double bonds and a 20 or 22 carbon atom chain length. The invention relates to the produc-tion of a Transgenic organism, preferably a Transgenic plant or a Transgenic Microorganism, hav-ing an increased content of fatty acids, oils or lipids containing C20- or C22- fatty acids with a delta-5, 7, 8, 10 double bond, respectively due to the expression of a delta-8-desaturase and a delta -9- elon-gase from organisms such as plants preferably Algae like Isochrysis galbana or Euglena gracilis. In addition the invention relates to a process for the production of poly unsaturated fatty acids such as Eicosapentaenoic, Arachidonic, Docosapentaenoic or Docosahexaenoic acid through the co- expression of a delta -8-desaturase, a delta-9-elongase and a delta-5 desaturase in organisms such as Microorganisms or plants.The invention additionally relates to the use of specific nucleic acid sequences encoding for the aforementioned proteins with delta-8-desaturase-, delta-9-elongase- or delta-5-desaturase-activity, nucleic acid constructs, vectors and organisms containing said nucleic acid sequences. The invention further relates to unsaturated fatty acids and triglycerides having an increased content of at least 1 % by weight of unsaturated fatty acids and use thereof

N S Pechurkin - One of the best experts on this subject based on the ideXlab platform.

  • experimental evaluation of the processes resulting from the introduction of the Transgenic Microorganism escherichia coli z905 pphl7 lux into aquatic microcosms
    Advances in Space Research, 2003
    Co-Authors: T V Kargatova, A N Boyandin, Yu L Popova, N S Pechurkin
    Abstract:

    The processes resulting from the introduction of the tranagenic Microorganism (TM) E. coli Z905/pPHL7 into aquatic microcosms have been modeled experimentally. It has been shown that the TM E. coli is able to adapt to a long co-existence with indigenous heterotropbic microflora in variously structured microcosms. In more complex microcosms the numerical dynamics of the introduced E. coli Z905/pPHL7 population is more stable. In the TM populations staying in the microcosms for a prolonged time, changes are recorded in the phenotypic expression of plasmid genes (ampicillin resistance and the luminescence level) and chromosome genes (morphological and physiological traits). However, in our study microcosms, the recombinant plasmid persisted in the TM cells for 6 years after the introduction, and as the population adapts to the conditions of the microcosms, the efficiency of the cloned gene expression in the cells is restored. In the microcosms with high microalgal counts (107 cells/ml), cells with a high threshold of sensitivity to ampicillin dominate in the population of the TM E. coli Z905/pPHL7.

  • stability of recombinant plasmids in Transgenic Microorganism cells under various environmental conditions
    Microbiology, 2001
    Co-Authors: Popova Liu, E E Maksimova, T I Lobova, T V Kargatova, A N Boiandin, Krylova Tiu, N S Pechurkin
    Abstract:

    The copy number of R plasmids weakly depends on the selective pressure of the respective antibiotic but does depend on the physiology of the host species and the type of plasmids and cloned genes, whose expression leads to a further load on the biosynthetic apparatus of cells. The last factor is critical in the maintenance of recombinant plasmids in Transgenic Microorganisms.

Zahringer U. - One of the best experts on this subject based on the ideXlab platform.

  • Novel Method For The Production Of Polyunsaturated Fatty Acids (Patent US 2006/0246556 A1)
    2006
    Co-Authors: Napier J. A., Sayanova O., Lazarus C., Qi B., Heinz E., Zank T., Zahringer U.
    Abstract:

    The present invention relates to an improved process for the specific production of poly-unsaturated omega-3 and omega-6 fatty acids and a process for the production of triglycerides having an increased content of unsaturated fatty acids, in particular omega-3 and omega-6 fatty acids having at least two double bonds and a 20 or 22 carbon atom chain length. The invention relates to the production of a Transgenic organism, preferably a Transgenic plant or a Transgenic Microorganism, hav-ing an increased content of fatty acids, oils or lipids containing C20- or C22-fatty acids with a delta-5, 7, 8, 10 double bond, respectively due to the expression of a delta-8-desaturase and a delta-9-elon-gase from organisms such as plants preferably Algae like Isochrysis galbana or Euglena gracilis. In addition the invention relates to a process for the production of poly unsaturated fatty acids such as Eicosapentaenoic, Arachidonic, Docosapentaenoic or Doosahexaenoic acid through the co-expression of a delta-8-desaturase, a delta-9-elongase and a delta-5 desaturase in organisms such as Microorganisms or plants. The invention additionally relates to the use of specific nucleic acid sequences encoding for the aforementioned proteins with delta-8-desaturase-, delta-9-elongase- or delta-5-desaturase-activity, nucleic acid constructs, vectors and organisms containing said nucleic acid sequences. The invention further relates to unsaturated fatty acids and triglycerides having an increased content of at least 1% by weight of unsaturated fatty acids and use thereof

  • Method For The Production Of Polyunsaturated Fatty Acids (Patent CA 2510462 A1)
    2004
    Co-Authors: Heinz E., Napier J. A., Sayanova O., Qi B., Zahringer U., Lazarus C. M., Zank T.
    Abstract:

    The present invention relates to an improved process for the specific production of poly-unsaturated omega-3 and omega-6 fatty acids and a process for the production of triglycerides having an increased content of unsaturat ed fatty acids, in particular omega-3 and omega-6 fatty acids having at least t wo double bonds and a 20 or 22 carbon atom chain length. The invention relates to the produc-tion of a Transgenic organism, preferably a Transgenic plant or a Transgenic Microorganism, hav-ing an increased content of fatty acids, oils or lipids containing C20- or C22- fatty acids with a delta-5, 7, 8, 10 double bond, respectively due to the expression of a delta-8-desaturase and a delta -9- elon-gase from organisms such as plants preferably Algae like Isochrysis galbana or Euglena gracilis. In addition the invention relates to a process for the production of poly unsaturated fatty acids such as Eicosapentaenoic, Arachidonic, Docosapentaenoic or Docosahexaenoic acid through the co- expression of a delta -8-desaturase, a delta-9-elongase and a delta-5 desaturase in organisms such as Microorganisms or plants.The invention additionally relates to the use of specific nucleic acid sequences encoding for the aforementioned proteins with delta-8-desaturase-, delta-9-elongase- or delta-5-desaturase-activity, nucleic acid constructs, vectors and organisms containing said nucleic acid sequences. The invention further relates to unsaturated fatty acids and triglycerides having an increased content of at least 1 % by weight of unsaturated fatty acids and use thereof