The Experts below are selected from a list of 309 Experts worldwide ranked by ideXlab platform
Toshinao Goda - One of the best experts on this subject based on the ideXlab platform.
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Fasting during the suckling-weaning Transient Period of rats induces inflammatory gene expression in the adipose tissue and peripheral leukocytes.
Nutrition (Burbank Los Angeles County Calif.), 2016Co-Authors: Kazue Honma, Riko Mawatari, Misa Iikeda, Kazuki Mochizuki, Toshinao GodaAbstract:Nutritional deficiency during developmental stages could be associated with subsequent development of inflammation-related metabolic abnormalities. In this study, we examined the effects of a 3-d fast during the suckling-weaning Transient Period of rats, and subsequent intake of high-fat-high-sucrose (HF) and low-fat-high-starch (LF) diets in adulthood, on the expression of inflammatory genes in adipose tissue and peripheral leukocytes. Male Sprague-Dawley rats were deprived of food for 3 d during the suckling-weaning Transient Period, and were subsequently fed an HF or LF diet for 14 wk from 17 wk of age. Serum monocyte chemoattractant protein-1 (MCP-1) concentration and mRNA levels of inflammatory genes in mesenteric adipose tissues were assessed at 31 wk of age. The mRNA levels of inflammatory genes at 0 h and 2 h after oral glucose load at 30 wk of age in peripheral leukocytes were measured. Fasting induced circulating MCP-1 protein in rats fed an LF diet but not an HF diet. The HF diet induced high mRNA levels of tumor necrosis factor-α, interleukin-1β, and S100 proteins in peripheral leukocytes at 2 h after glucose load in fasted rats when compared with controls. Expression of CD11c, an activated macrophage marker, was induced in the fasted group given an HF diet during adulthood. Fasting rats during the suckling-weaning Transient Period and an HF diet intake during adulthood enhance inflammation by promoting the expression of inflammatory genes in adipose tissue and peripheral leukocytes. Copyright © 2016 Elsevier Inc. All rights reserved.
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Fasting during the suckling-weaning Transient Period of rats induces inflammatory gene expression in the adipose tissue and peripheral leukocytes.
Nutrition, 2016Co-Authors: Kazue Honma, Riko Mawatari, Misa Iikeda, Kazuki Mochizuki, Toshinao GodaAbstract:Abstract Objective Nutritional deficiency during developmental stages could be associated with subsequent development of inflammation-related metabolic abnormalities. In this study, we examined the effects of a 3-d fast during the suckling-weaning Transient Period of rats, and subsequent intake of high-fat–high-sucrose (HF) and low-fat–high-starch (LF) diets in adulthood, on the expression of inflammatory genes in adipose tissue and peripheral leukocytes. Methods Male Sprague-Dawley rats were deprived of food for 3 d during the suckling-weaning Transient Period, and were subsequently fed an HF or LF diet for 14 wk from 17 wk of age. Serum monocyte chemoattractant protein-1 (MCP-1) concentration and mRNA levels of inflammatory genes in mesenteric adipose tissues were assessed at 31 wk of age. The mRNA levels of inflammatory genes at 0 h and 2 h after oral glucose load at 30 wk of age in peripheral leukocytes were measured. Results Fasting induced circulating MCP-1 protein in rats fed an LF diet but not an HF diet. The HF diet induced high mRNA levels of tumor necrosis factor-α, interleukin-1β, and S100 proteins in peripheral leukocytes at 2 h after glucose load in fasted rats when compared with controls. Expression of CD11c, an activated macrophage marker, was induced in the fasted group given an HF diet during adulthood. Conclusions Fasting rats during the suckling-weaning Transient Period and an HF diet intake during adulthood enhance inflammation by promoting the expression of inflammatory genes in adipose tissue and peripheral leukocytes.
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Fasting for 3 days during the suckling-weaning Transient Period in male rats induces metabolic abnormalities in the liver and is associated with impaired glucose tolerance in adulthood
European journal of nutrition, 2015Co-Authors: Misa Ikeda, Kazue Honma, Kazuki Mochizuki, Toshinao GodaAbstract:Purpose Recent studies suggest that nutritional status during developmental Periods is associated with subsequent development of metabolic abnormalities. In this study, we examined whether malnutrition by fasting for 3 days during the suckling–weaning Transient Period induces subsequent development of metabolic abnormalities in rats.
Li Jingya - One of the best experts on this subject based on the ideXlab platform.
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GLOBECOM Workshops - On the Impact of Transient Period for Short Transmission Duration
2017 IEEE Globecom Workshops (GC Wkshps), 2017Co-Authors: Marten Sundberg, Gustav Almquist, Zhao Hongxia, Li JingyaAbstract:Low latency is the key not only for improving the user experience of today's applications but also for realizing the emerging critical machine type communication use cases for 5G. In 4G and 5G standardization by 3GPP, shortening the transmission duration has been considered as an important technology for latency reduction in future wireless networks. As the transmission duration is shortened, the Period when the signal is not well defined due to RF limitations, will naturally become a larger portion of the overall uplink transmission, unless also shortened. This Period, commonly referred to as a Transient Period, can result in the useful signal being distorted and/or cause interference to other users. This paper investigates the impact of the Transient Period on LTE uplink transmissions shortened by a factor 7 or 2 compared to legacy LTE. Different approaches are proposed in this paper to reduce the Transient Period impact. Our link level simulation results show that by reducing the Transient Period duration from 20 µs to 10 µs, around 1.8 dB signal-to-noise ratio gain can be achieved, considering the operation points for typical mobile broadband services. It is shown that placing the Transient Period outside the allocated transmission duration is preferred despite increased inter-user interference. Moreover, by using a specific characteristic of the reference signal design, the performance gain can be further improved.
Kazue Honma - One of the best experts on this subject based on the ideXlab platform.
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Fasting during the suckling-weaning Transient Period of rats induces inflammatory gene expression in the adipose tissue and peripheral leukocytes.
Nutrition (Burbank Los Angeles County Calif.), 2016Co-Authors: Kazue Honma, Riko Mawatari, Misa Iikeda, Kazuki Mochizuki, Toshinao GodaAbstract:Nutritional deficiency during developmental stages could be associated with subsequent development of inflammation-related metabolic abnormalities. In this study, we examined the effects of a 3-d fast during the suckling-weaning Transient Period of rats, and subsequent intake of high-fat-high-sucrose (HF) and low-fat-high-starch (LF) diets in adulthood, on the expression of inflammatory genes in adipose tissue and peripheral leukocytes. Male Sprague-Dawley rats were deprived of food for 3 d during the suckling-weaning Transient Period, and were subsequently fed an HF or LF diet for 14 wk from 17 wk of age. Serum monocyte chemoattractant protein-1 (MCP-1) concentration and mRNA levels of inflammatory genes in mesenteric adipose tissues were assessed at 31 wk of age. The mRNA levels of inflammatory genes at 0 h and 2 h after oral glucose load at 30 wk of age in peripheral leukocytes were measured. Fasting induced circulating MCP-1 protein in rats fed an LF diet but not an HF diet. The HF diet induced high mRNA levels of tumor necrosis factor-α, interleukin-1β, and S100 proteins in peripheral leukocytes at 2 h after glucose load in fasted rats when compared with controls. Expression of CD11c, an activated macrophage marker, was induced in the fasted group given an HF diet during adulthood. Fasting rats during the suckling-weaning Transient Period and an HF diet intake during adulthood enhance inflammation by promoting the expression of inflammatory genes in adipose tissue and peripheral leukocytes. Copyright © 2016 Elsevier Inc. All rights reserved.
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Fasting during the suckling-weaning Transient Period of rats induces inflammatory gene expression in the adipose tissue and peripheral leukocytes.
Nutrition, 2016Co-Authors: Kazue Honma, Riko Mawatari, Misa Iikeda, Kazuki Mochizuki, Toshinao GodaAbstract:Abstract Objective Nutritional deficiency during developmental stages could be associated with subsequent development of inflammation-related metabolic abnormalities. In this study, we examined the effects of a 3-d fast during the suckling-weaning Transient Period of rats, and subsequent intake of high-fat–high-sucrose (HF) and low-fat–high-starch (LF) diets in adulthood, on the expression of inflammatory genes in adipose tissue and peripheral leukocytes. Methods Male Sprague-Dawley rats were deprived of food for 3 d during the suckling-weaning Transient Period, and were subsequently fed an HF or LF diet for 14 wk from 17 wk of age. Serum monocyte chemoattractant protein-1 (MCP-1) concentration and mRNA levels of inflammatory genes in mesenteric adipose tissues were assessed at 31 wk of age. The mRNA levels of inflammatory genes at 0 h and 2 h after oral glucose load at 30 wk of age in peripheral leukocytes were measured. Results Fasting induced circulating MCP-1 protein in rats fed an LF diet but not an HF diet. The HF diet induced high mRNA levels of tumor necrosis factor-α, interleukin-1β, and S100 proteins in peripheral leukocytes at 2 h after glucose load in fasted rats when compared with controls. Expression of CD11c, an activated macrophage marker, was induced in the fasted group given an HF diet during adulthood. Conclusions Fasting rats during the suckling-weaning Transient Period and an HF diet intake during adulthood enhance inflammation by promoting the expression of inflammatory genes in adipose tissue and peripheral leukocytes.
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Fasting for 3 days during the suckling-weaning Transient Period in male rats induces metabolic abnormalities in the liver and is associated with impaired glucose tolerance in adulthood
European journal of nutrition, 2015Co-Authors: Misa Ikeda, Kazue Honma, Kazuki Mochizuki, Toshinao GodaAbstract:Purpose Recent studies suggest that nutritional status during developmental Periods is associated with subsequent development of metabolic abnormalities. In this study, we examined whether malnutrition by fasting for 3 days during the suckling–weaning Transient Period induces subsequent development of metabolic abnormalities in rats.
Marten Sundberg - One of the best experts on this subject based on the ideXlab platform.
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On the Impact of Transient Period for Short Transmission Duration
2017 IEEE Globecom Workshops (GC Wkshps), 2017Co-Authors: Marten Sundberg, Gustav Almquist, Hongxia Zhao, Jingya LiAbstract:Low latency is the key not only for improving the user experience of today's applications but also for realizing the emerging critical machine type communication use cases for 5G. In 4G and 5G standardization by 3GPP, shortening the transmission duration has been considered as an important technology for latency reduction in future wireless networks. As the transmission duration is shortened, the Period when the signal is not well defined due to RF limitations, will naturally become a larger portion of the overall uplink transmission, unless also shortened. This Period, commonly referred to as a Transient Period, can result in the useful signal being distorted and/or cause interference to other users. This paper investigates the impact of the Transient Period on LTE uplink transmissions shortened by a factor 7 or 2 compared to legacy LTE. Different approaches are proposed in this paper to reduce the Transient Period impact. Our link level simulation results show that by reducing the Transient Period duration from 20 μs to 10 μs, around 1.8 dB signal-to-noise ratio gain can be achieved, considering the operation points for typical mobile broadband services. It is shown that placing the Transient Period outside the allocated transmission duration is preferred despite increased inter-user interference. Moreover, by using a specific characteristic of the reference signal design, the performance gain can be further improved.
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GLOBECOM Workshops - On the Impact of Transient Period for Short Transmission Duration
2017 IEEE Globecom Workshops (GC Wkshps), 2017Co-Authors: Marten Sundberg, Gustav Almquist, Zhao Hongxia, Li JingyaAbstract:Low latency is the key not only for improving the user experience of today's applications but also for realizing the emerging critical machine type communication use cases for 5G. In 4G and 5G standardization by 3GPP, shortening the transmission duration has been considered as an important technology for latency reduction in future wireless networks. As the transmission duration is shortened, the Period when the signal is not well defined due to RF limitations, will naturally become a larger portion of the overall uplink transmission, unless also shortened. This Period, commonly referred to as a Transient Period, can result in the useful signal being distorted and/or cause interference to other users. This paper investigates the impact of the Transient Period on LTE uplink transmissions shortened by a factor 7 or 2 compared to legacy LTE. Different approaches are proposed in this paper to reduce the Transient Period impact. Our link level simulation results show that by reducing the Transient Period duration from 20 µs to 10 µs, around 1.8 dB signal-to-noise ratio gain can be achieved, considering the operation points for typical mobile broadband services. It is shown that placing the Transient Period outside the allocated transmission duration is preferred despite increased inter-user interference. Moreover, by using a specific characteristic of the reference signal design, the performance gain can be further improved.
Kazuki Mochizuki - One of the best experts on this subject based on the ideXlab platform.
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Fasting during the suckling-weaning Transient Period of rats induces inflammatory gene expression in the adipose tissue and peripheral leukocytes.
Nutrition (Burbank Los Angeles County Calif.), 2016Co-Authors: Kazue Honma, Riko Mawatari, Misa Iikeda, Kazuki Mochizuki, Toshinao GodaAbstract:Nutritional deficiency during developmental stages could be associated with subsequent development of inflammation-related metabolic abnormalities. In this study, we examined the effects of a 3-d fast during the suckling-weaning Transient Period of rats, and subsequent intake of high-fat-high-sucrose (HF) and low-fat-high-starch (LF) diets in adulthood, on the expression of inflammatory genes in adipose tissue and peripheral leukocytes. Male Sprague-Dawley rats were deprived of food for 3 d during the suckling-weaning Transient Period, and were subsequently fed an HF or LF diet for 14 wk from 17 wk of age. Serum monocyte chemoattractant protein-1 (MCP-1) concentration and mRNA levels of inflammatory genes in mesenteric adipose tissues were assessed at 31 wk of age. The mRNA levels of inflammatory genes at 0 h and 2 h after oral glucose load at 30 wk of age in peripheral leukocytes were measured. Fasting induced circulating MCP-1 protein in rats fed an LF diet but not an HF diet. The HF diet induced high mRNA levels of tumor necrosis factor-α, interleukin-1β, and S100 proteins in peripheral leukocytes at 2 h after glucose load in fasted rats when compared with controls. Expression of CD11c, an activated macrophage marker, was induced in the fasted group given an HF diet during adulthood. Fasting rats during the suckling-weaning Transient Period and an HF diet intake during adulthood enhance inflammation by promoting the expression of inflammatory genes in adipose tissue and peripheral leukocytes. Copyright © 2016 Elsevier Inc. All rights reserved.
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Fasting during the suckling-weaning Transient Period of rats induces inflammatory gene expression in the adipose tissue and peripheral leukocytes.
Nutrition, 2016Co-Authors: Kazue Honma, Riko Mawatari, Misa Iikeda, Kazuki Mochizuki, Toshinao GodaAbstract:Abstract Objective Nutritional deficiency during developmental stages could be associated with subsequent development of inflammation-related metabolic abnormalities. In this study, we examined the effects of a 3-d fast during the suckling-weaning Transient Period of rats, and subsequent intake of high-fat–high-sucrose (HF) and low-fat–high-starch (LF) diets in adulthood, on the expression of inflammatory genes in adipose tissue and peripheral leukocytes. Methods Male Sprague-Dawley rats were deprived of food for 3 d during the suckling-weaning Transient Period, and were subsequently fed an HF or LF diet for 14 wk from 17 wk of age. Serum monocyte chemoattractant protein-1 (MCP-1) concentration and mRNA levels of inflammatory genes in mesenteric adipose tissues were assessed at 31 wk of age. The mRNA levels of inflammatory genes at 0 h and 2 h after oral glucose load at 30 wk of age in peripheral leukocytes were measured. Results Fasting induced circulating MCP-1 protein in rats fed an LF diet but not an HF diet. The HF diet induced high mRNA levels of tumor necrosis factor-α, interleukin-1β, and S100 proteins in peripheral leukocytes at 2 h after glucose load in fasted rats when compared with controls. Expression of CD11c, an activated macrophage marker, was induced in the fasted group given an HF diet during adulthood. Conclusions Fasting rats during the suckling-weaning Transient Period and an HF diet intake during adulthood enhance inflammation by promoting the expression of inflammatory genes in adipose tissue and peripheral leukocytes.
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Fasting for 3 days during the suckling-weaning Transient Period in male rats induces metabolic abnormalities in the liver and is associated with impaired glucose tolerance in adulthood
European journal of nutrition, 2015Co-Authors: Misa Ikeda, Kazue Honma, Kazuki Mochizuki, Toshinao GodaAbstract:Purpose Recent studies suggest that nutritional status during developmental Periods is associated with subsequent development of metabolic abnormalities. In this study, we examined whether malnutrition by fasting for 3 days during the suckling–weaning Transient Period induces subsequent development of metabolic abnormalities in rats.
