Transthoracic Biopsy

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Andreas H. Diacon - One of the best experts on this subject based on the ideXlab platform.

  • The diagnostic yield and safety of ultrasound-assisted Transthoracic Biopsy of mediastinal masses.
    Respiration; international review of thoracic diseases, 2010
    Co-Authors: Coenraad F.n. Koegelenberg, Andreas H. Diacon, Elvis M. Irusen, Florian Von Groote-bidlingmaier, Abdurasiet Mowlana, Colleen A. Wright, Mercia Louw, Pawel T. Schubert, Chris T. Bolliger
    Abstract:

    Background: Ultrasound (US)-assisted Transthoracic Biopsy offers a less invasive alternative to surgical Biopsy in the setting of mediastinal masses. Objectives:

  • Ultrasound-assisted Transthoracic Biopsy: fine-needle aspiration or cutting-needle Biopsy?
    The European respiratory journal, 2006
    Co-Authors: Andreas H. Diacon, Colleen A. Wright, Mercia Louw, Pawel T. Schubert, K. Brundyn, Johan Theron, C.t. Bolliger
    Abstract:

    The present study compared the diagnostic yield of ultrasound-assisted cutting-needle Biopsy (CNB) and fine-needle aspiration Biopsy (FNAB) in chest lesions. A physician performed ultrasound and FNAB with a 22-G spinal needle in all patients, directly followed by a 14-G CNB in patients without contraindication. A total of 155 consecutive lesions arising from the lung (74%), pleura (12%), mediastinum (11%) or chest wall (3%) in patients with a final diagnosis of lung carcinoma (74%), other malignant tumours (12%), non-neoplastic disease (9%) or unknown (5%) were prospectively included. The overall diagnostic yield was 87%. Combined specimens were obtained in 123 lesions (79%). In these, yields of FNAB, CNB and both methods combined were 82, 76 and 89%, respectively. FNAB was significantly better than CNB in lung carcinoma (95 versus 81%) but CNB was superior in noncarcinomatous tumours and in benign lesions. On-site cytology was 90% sensitive and 100% specific for predicting a positive FNAB. One patient required drainage for pneumothorax (0.6%). Ultrasound-assisted fine-needle aspiration Biopsy performed by chest physicians is an accurate and safe initial diagnostic procedure in patients with a high clinical probability of lung carcinoma. All other patients should undergo concurrent fine-needle aspiration Biopsy and cutting-needle Biopsy.

  • Ultrasound-assisted Transthoracic Biopsy: cells or sections?
    Diagnostic cytopathology, 2005
    Co-Authors: Pawel T. Schubert, Colleen A. Wright, Mercia Louw, Chris T. Bolliger, K. Brundyn, Johan Theron, Andreas H. Diacon
    Abstract:

    Physicians increasingly use Transthoracic ultrasound (US) as an aid for diagnostic procedures. At the bedside, US helps to visualize neoplasms in the chest wall, pleura, peripheral lung, and anterior mediastinum involving or abutting the pleura. Histology specimens from cutting-needle biopsies have been shown to be safe and effective. This prospective study determined the yield and safety of US-guided fine-needle aspiration Biopsy (FNAB) as a first-line bedside investigation. We recruited 97 consecutive patients, and of these, 85 underwent both cutting-needle Biopsy and FNAB. These were adequate for diagnosis in 81.2% and 80% of cases, respectively, with a combined yield of 90%. Measured with a novel semiquantitative score, FNAB allowed a diagnosis with fewer special investigations than cutting Biopsy. US-guided FNAB by pulmonologists performed best in lung carcinoma and can be recommended as a first-line investigation in patients with a high clinical suspicion of this diagnosis. Diagn. Cytopathol. 2005;33:233–237. © 2005 Wiley-Liss, Inc.

  • Safety and yield of ultrasound-assisted Transthoracic Biopsy performed by pulmonologists.
    Respiration; international review of thoracic diseases, 2004
    Co-Authors: Andreas H. Diacon, Colleen A. Wright, Pawel T. Schubert, Johan Theron, Macé M. Schuurmans, C.t. Bolliger
    Abstract:

    Background: Transthoracic ultrasound (US) has gained popularity as a tool for visualizing pleural effusions and assisting thoracentesis or chest drain placement. In the absence of e

Pan-chyr Yang - One of the best experts on this subject based on the ideXlab platform.

  • ultrasound guided Transthoracic Biopsy of the chest
    Radiologic Clinics of North America, 2000
    Co-Authors: Pan-chyr Yang
    Abstract:

    Recent studies have confirmed that US is a very useful diagnostic tool for various diseases of the chest. The image information provided by US is helpful for etiologic diagnosis and clinical management. US-guided needle Biopsy provides a precise and safe approach for Transthoracic tissue sampling of lesions. The diagnostic yield is high, and the procedure is relatively easy and very safe. Color Doppler US and amplitude US angiography further extend the diagnostic potential and safety of this invasive procedure. Vascular information can be obtained and the needle shaft can be visualized clearly while conducting a Biopsy. US examination and US-guided needle aspiration Biopsy have now become indispensable diagnostic tools for various chest diseases.

  • Ultrasound-guided Transthoracic Biopsy of the chest.
    Radiologic clinics of North America, 2000
    Co-Authors: Pan-chyr Yang
    Abstract:

    Advances in technology have greatly improved the imaging capabilities of ultrasound (US). This article summarizes the current applications of US as a diagnostic tool in chest diseases. By scanning through the acoustic window, US is a very reliable and efficient tool for evaluating lesions of the chest wall, pleural cavity, peridiaphragm, mediastinum, hilum, and peripheral lungs. A precise puncture transducer can be used to perform US-guided Transthoracic needle Biopsy (TNB) with real-time visualization of the Biopsy needle and the lesion. The accuracy of US-guided TNB for peripheral pulmonary nodules, chest wall lesions, and mediastinal tumors is 88% to 100%. US-guided TNB is also useful for histologic diagnosis of tumors causing superior vena cava (SVC) syndrome, Pancoast's tumors, pulmonary consolidation of unknown etiology, and tumors with obstructive pneumonitis. Moreover, Transthoracic needle aspiration under US guidance can provide adequate specimens for microbiologic diagnosis of lung abscesses, necrotizing pneumonia, and parapneumonic effusions. Color Doppler imaging further extends the diagnostic spectrum of US, allowing the hemodynamics and neovascularization of a pulmonary lesion to be assessed noninvasively. Pulmonary arteriovenous malformations, pulmonary sequestration, and pulmonary infarctions can be diagnosed easily with color Doppler US. The color Doppler US puncture guiding device can improve the safety of US-guided TNB by simultaneously displaying blood vessel information, the needle shaft, and the puncture route. US examination and US-guided TNB have become indispensable diagnostic techniques for various chest diseases. TNB with imaging guidance is a well-established technique for the diagnosis of focal pulmonary lesions. 6,22 CT and biplane fluoroscopy are the most common imaging modalities used to guide TNB. With advances in imaging capabilities, Biopsy techniques, and cytopathology, CT- and fluoroscopy-guided TNB can now provide extremely high diagnostic yields (sensitivity 80% to 95%) and are relatively safe. 6,21 These diagnostic modalities may be time-consuming, however, especially for small peripheral pulmonary lesions, and carry the risk of excessive exposure to radiation. Recently, rapid advances in transducer design, signal processing, and Doppler technology have greatly improved the imaging quality of US. With the development of a precise puncture-guiding device, US has proved to be a reliable, efficient, and informative imaging modality for evaluation of a wide variety of complicated clinical problems associated with chest diseases. 12,26,32,33,35,36,37,38,39,40,41,43 It can also be used effectively to guide TNB and other interventional procedures in the thorax. 1,2,5,8,13,19,28,29,30,31,34 This article presents an overview of the state-of-art applications of US-guided Transthoracic Biopsy in chest diseases including indications and contraindications, imaging techniques, Biopsy procedures, diagnostic spectrum and sensitivity, potential complications, and advantages and limitations.

  • Ultrasound-guided Transthoracic Biopsy of peripheral lung, pleural, and chest-wall lesions.
    Journal of thoracic imaging, 1997
    Co-Authors: Pan-chyr Yang
    Abstract:

    Ultrasound (US)-guided Transthoracic Biopsy is well suited for the sampling of those mediastinal, hilar, pleural, chest-wall, and peripheral lung lesions that provide an adequate acoustic window to the transducer. Chest-wall, pleural, and peripheral lung lesions are generally hypoechoic relative to their surrounding tissues. A special puncture transducer is used to perform US-guided Biopsy with real-time visualization of the Biopsy needle and the lesion. For vascular lesions and lesions adjacent to mediastinal vessels, a color Doppler puncture device is now available. The accuracy of US-guided Biopsy of peripheral lung lesions or chest-wall lesions is 88% to 100%, with particular utility in the diagnosis of pulmonary masses with large necrotic centers. Other lung lesions amenable to US-guided Biopsy diagnosis include those producing superior vena cava (SVC) syndrome, Pancoast's syndrome, or obstructive pneumonitis. Pulmonary consolidation, lung abscess, and parapneumonic effusions are easily sampled for microbiologic diagnosis. The peripheral nature of lesions accessed by US guidance accounts for a very low rate of complications. Although US-guided needle Biopsy requires certain expertise, the technique is relatively easy to master and can be performed in many situations where computed tomography-guided Biopsy would previously have been used.

Colleen A. Wright - One of the best experts on this subject based on the ideXlab platform.

  • The diagnostic yield and safety of ultrasound-assisted Transthoracic Biopsy of mediastinal masses.
    Respiration; international review of thoracic diseases, 2010
    Co-Authors: Coenraad F.n. Koegelenberg, Andreas H. Diacon, Elvis M. Irusen, Florian Von Groote-bidlingmaier, Abdurasiet Mowlana, Colleen A. Wright, Mercia Louw, Pawel T. Schubert, Chris T. Bolliger
    Abstract:

    Background: Ultrasound (US)-assisted Transthoracic Biopsy offers a less invasive alternative to surgical Biopsy in the setting of mediastinal masses. Objectives:

  • Ultrasound-assisted Transthoracic Biopsy: fine-needle aspiration or cutting-needle Biopsy?
    The European respiratory journal, 2006
    Co-Authors: Andreas H. Diacon, Colleen A. Wright, Mercia Louw, Pawel T. Schubert, K. Brundyn, Johan Theron, C.t. Bolliger
    Abstract:

    The present study compared the diagnostic yield of ultrasound-assisted cutting-needle Biopsy (CNB) and fine-needle aspiration Biopsy (FNAB) in chest lesions. A physician performed ultrasound and FNAB with a 22-G spinal needle in all patients, directly followed by a 14-G CNB in patients without contraindication. A total of 155 consecutive lesions arising from the lung (74%), pleura (12%), mediastinum (11%) or chest wall (3%) in patients with a final diagnosis of lung carcinoma (74%), other malignant tumours (12%), non-neoplastic disease (9%) or unknown (5%) were prospectively included. The overall diagnostic yield was 87%. Combined specimens were obtained in 123 lesions (79%). In these, yields of FNAB, CNB and both methods combined were 82, 76 and 89%, respectively. FNAB was significantly better than CNB in lung carcinoma (95 versus 81%) but CNB was superior in noncarcinomatous tumours and in benign lesions. On-site cytology was 90% sensitive and 100% specific for predicting a positive FNAB. One patient required drainage for pneumothorax (0.6%). Ultrasound-assisted fine-needle aspiration Biopsy performed by chest physicians is an accurate and safe initial diagnostic procedure in patients with a high clinical probability of lung carcinoma. All other patients should undergo concurrent fine-needle aspiration Biopsy and cutting-needle Biopsy.

  • Ultrasound-assisted Transthoracic Biopsy: cells or sections?
    Diagnostic cytopathology, 2005
    Co-Authors: Pawel T. Schubert, Colleen A. Wright, Mercia Louw, Chris T. Bolliger, K. Brundyn, Johan Theron, Andreas H. Diacon
    Abstract:

    Physicians increasingly use Transthoracic ultrasound (US) as an aid for diagnostic procedures. At the bedside, US helps to visualize neoplasms in the chest wall, pleura, peripheral lung, and anterior mediastinum involving or abutting the pleura. Histology specimens from cutting-needle biopsies have been shown to be safe and effective. This prospective study determined the yield and safety of US-guided fine-needle aspiration Biopsy (FNAB) as a first-line bedside investigation. We recruited 97 consecutive patients, and of these, 85 underwent both cutting-needle Biopsy and FNAB. These were adequate for diagnosis in 81.2% and 80% of cases, respectively, with a combined yield of 90%. Measured with a novel semiquantitative score, FNAB allowed a diagnosis with fewer special investigations than cutting Biopsy. US-guided FNAB by pulmonologists performed best in lung carcinoma and can be recommended as a first-line investigation in patients with a high clinical suspicion of this diagnosis. Diagn. Cytopathol. 2005;33:233–237. © 2005 Wiley-Liss, Inc.

  • Safety and yield of ultrasound-assisted Transthoracic Biopsy performed by pulmonologists.
    Respiration; international review of thoracic diseases, 2004
    Co-Authors: Andreas H. Diacon, Colleen A. Wright, Pawel T. Schubert, Johan Theron, Macé M. Schuurmans, C.t. Bolliger
    Abstract:

    Background: Transthoracic ultrasound (US) has gained popularity as a tool for visualizing pleural effusions and assisting thoracentesis or chest drain placement. In the absence of e

Pawel T. Schubert - One of the best experts on this subject based on the ideXlab platform.

  • The diagnostic yield and safety of ultrasound-assisted Transthoracic Biopsy of mediastinal masses.
    Respiration; international review of thoracic diseases, 2010
    Co-Authors: Coenraad F.n. Koegelenberg, Andreas H. Diacon, Elvis M. Irusen, Florian Von Groote-bidlingmaier, Abdurasiet Mowlana, Colleen A. Wright, Mercia Louw, Pawel T. Schubert, Chris T. Bolliger
    Abstract:

    Background: Ultrasound (US)-assisted Transthoracic Biopsy offers a less invasive alternative to surgical Biopsy in the setting of mediastinal masses. Objectives:

  • Ultrasound-assisted Transthoracic Biopsy: fine-needle aspiration or cutting-needle Biopsy?
    The European respiratory journal, 2006
    Co-Authors: Andreas H. Diacon, Colleen A. Wright, Mercia Louw, Pawel T. Schubert, K. Brundyn, Johan Theron, C.t. Bolliger
    Abstract:

    The present study compared the diagnostic yield of ultrasound-assisted cutting-needle Biopsy (CNB) and fine-needle aspiration Biopsy (FNAB) in chest lesions. A physician performed ultrasound and FNAB with a 22-G spinal needle in all patients, directly followed by a 14-G CNB in patients without contraindication. A total of 155 consecutive lesions arising from the lung (74%), pleura (12%), mediastinum (11%) or chest wall (3%) in patients with a final diagnosis of lung carcinoma (74%), other malignant tumours (12%), non-neoplastic disease (9%) or unknown (5%) were prospectively included. The overall diagnostic yield was 87%. Combined specimens were obtained in 123 lesions (79%). In these, yields of FNAB, CNB and both methods combined were 82, 76 and 89%, respectively. FNAB was significantly better than CNB in lung carcinoma (95 versus 81%) but CNB was superior in noncarcinomatous tumours and in benign lesions. On-site cytology was 90% sensitive and 100% specific for predicting a positive FNAB. One patient required drainage for pneumothorax (0.6%). Ultrasound-assisted fine-needle aspiration Biopsy performed by chest physicians is an accurate and safe initial diagnostic procedure in patients with a high clinical probability of lung carcinoma. All other patients should undergo concurrent fine-needle aspiration Biopsy and cutting-needle Biopsy.

  • Ultrasound-assisted Transthoracic Biopsy: cells or sections?
    Diagnostic cytopathology, 2005
    Co-Authors: Pawel T. Schubert, Colleen A. Wright, Mercia Louw, Chris T. Bolliger, K. Brundyn, Johan Theron, Andreas H. Diacon
    Abstract:

    Physicians increasingly use Transthoracic ultrasound (US) as an aid for diagnostic procedures. At the bedside, US helps to visualize neoplasms in the chest wall, pleura, peripheral lung, and anterior mediastinum involving or abutting the pleura. Histology specimens from cutting-needle biopsies have been shown to be safe and effective. This prospective study determined the yield and safety of US-guided fine-needle aspiration Biopsy (FNAB) as a first-line bedside investigation. We recruited 97 consecutive patients, and of these, 85 underwent both cutting-needle Biopsy and FNAB. These were adequate for diagnosis in 81.2% and 80% of cases, respectively, with a combined yield of 90%. Measured with a novel semiquantitative score, FNAB allowed a diagnosis with fewer special investigations than cutting Biopsy. US-guided FNAB by pulmonologists performed best in lung carcinoma and can be recommended as a first-line investigation in patients with a high clinical suspicion of this diagnosis. Diagn. Cytopathol. 2005;33:233–237. © 2005 Wiley-Liss, Inc.

  • Safety and yield of ultrasound-assisted Transthoracic Biopsy performed by pulmonologists.
    Respiration; international review of thoracic diseases, 2004
    Co-Authors: Andreas H. Diacon, Colleen A. Wright, Pawel T. Schubert, Johan Theron, Macé M. Schuurmans, C.t. Bolliger
    Abstract:

    Background: Transthoracic ultrasound (US) has gained popularity as a tool for visualizing pleural effusions and assisting thoracentesis or chest drain placement. In the absence of e

C.t. Bolliger - One of the best experts on this subject based on the ideXlab platform.

  • Ultrasound-assisted Transthoracic Biopsy: fine-needle aspiration or cutting-needle Biopsy?
    The European respiratory journal, 2006
    Co-Authors: Andreas H. Diacon, Colleen A. Wright, Mercia Louw, Pawel T. Schubert, K. Brundyn, Johan Theron, C.t. Bolliger
    Abstract:

    The present study compared the diagnostic yield of ultrasound-assisted cutting-needle Biopsy (CNB) and fine-needle aspiration Biopsy (FNAB) in chest lesions. A physician performed ultrasound and FNAB with a 22-G spinal needle in all patients, directly followed by a 14-G CNB in patients without contraindication. A total of 155 consecutive lesions arising from the lung (74%), pleura (12%), mediastinum (11%) or chest wall (3%) in patients with a final diagnosis of lung carcinoma (74%), other malignant tumours (12%), non-neoplastic disease (9%) or unknown (5%) were prospectively included. The overall diagnostic yield was 87%. Combined specimens were obtained in 123 lesions (79%). In these, yields of FNAB, CNB and both methods combined were 82, 76 and 89%, respectively. FNAB was significantly better than CNB in lung carcinoma (95 versus 81%) but CNB was superior in noncarcinomatous tumours and in benign lesions. On-site cytology was 90% sensitive and 100% specific for predicting a positive FNAB. One patient required drainage for pneumothorax (0.6%). Ultrasound-assisted fine-needle aspiration Biopsy performed by chest physicians is an accurate and safe initial diagnostic procedure in patients with a high clinical probability of lung carcinoma. All other patients should undergo concurrent fine-needle aspiration Biopsy and cutting-needle Biopsy.

  • Safety and yield of ultrasound-assisted Transthoracic Biopsy performed by pulmonologists.
    Respiration; international review of thoracic diseases, 2004
    Co-Authors: Andreas H. Diacon, Colleen A. Wright, Pawel T. Schubert, Johan Theron, Macé M. Schuurmans, C.t. Bolliger
    Abstract:

    Background: Transthoracic ultrasound (US) has gained popularity as a tool for visualizing pleural effusions and assisting thoracentesis or chest drain placement. In the absence of e

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