Treatment Outcome

14,000,000 Leading Edge Experts on the ideXlab platform

Scan Science and Technology

Contact Leading Edge Experts & Companies

Scan Science and Technology

Contact Leading Edge Experts & Companies

The Experts below are selected from a list of 321 Experts worldwide ranked by ideXlab platform

Peter A Cistulli - One of the best experts on this subject based on the ideXlab platform.

  • cephalometry and prediction of oral appliance Treatment Outcome
    Sleep and Breathing, 2012
    Co-Authors: Ali M Darendeliler, Peter Petocz, Peter A Cistulli
    Abstract:

    Predicting which patients with obstructive sleep apnea (OSA) will be successfully treated with mandibular advancement splints (MAS) remains elusive. Developing simple daytime measurements and tests to predict Treatment Outcome would enhance MAS Treatment. The purpose of this study was to assess the clinical utility of anthropomorphic measurements and cephalometric X-rays in the prediction of MAS Treatment Outcome in OSA. Anthropomorphic measurements and cephalometric X-rays from 72 OSA patients who had presented to a tertiary referral sleep clinic were analyzed retrospectively. Treatment response was defined as ≥50% reduction in Apnea/Hypopnea Index (AHI; criterion 1); ≥50% reduction and residual AHI less than 20/h (criterion 2); ≥50% reduction in AHI and residual AHI less than 10/h (criterion 3); and ≥50% reduction in AHI and residual AHI less than 5/h (criterion 4). This was done to reflect the differences in the clinical definition of Treatment success in the literature. A good response occurred in 56% (40 patients) according to criterion 1; 54% (39 patients) according to criterion 2; 46% (33 patients) according to criterion 3; or 39% (28 patients) according to criterion 4. Age and gender were found to be significant predictors for criteria 1 and 2. Age and soft palate length were found to be significant predictors for criteria 3 and 4. Equations to predict MAS Treatment response were derived as equations were to predict final AHI. Certain cephalometric and anthropomorphic measurements impact on MAS Treatment Outcome. This study adds to the current literature and implies that MAS success is (to some degree) related to anatomical characteristics.

  • influence of nasal resistance on oral appliance Treatment Outcome in obstructive sleep apnea
    Sleep, 2008
    Co-Authors: Ali M Darendeliler, Peter Petocz, Peter A Cistulli, Biao Zeng, Jin Qian
    Abstract:

    It has been recognized that nasal airway resistance (NAR) is elevated in patients with OSA. However, little is known regarding the influence of nasal resistance on mandibular advancement splint (MAS) Treatment Outcome in OSA patient. We hypothesized that nasal resistance differs between MAS responders and nonresponders and therefore may influence Treatment Outcome. Thirty-eight patients with known OSA underwent polysomnography while wearing a custom-made MAS. Treatment Outcome was defined as follows: Responders (R) ≥50% reduction in AHI, and Nonresponders (NR) as <50% reduction in AHI. NAR was measured using posterior rhinomanometry in both sitting and supine positions, with and without MAS. The mean AHI in 26 responders was significantly reduced from 29.0 ± 2.9/h to 6.7 ± 1.2/h; P < 0.01). In 12 nonresponders there was no significant change in AHI (23.9 ± 3.0/h vs 22.0 ± 4.3/h; P=ns). Baseline NAR was significantly lower in responders in the sitting position compared to nonresponders (6.5 ± 0.5 vs 9.4 ± 1.0cm H2O; P < 0.01). There was no significant change in NAR (from baseline) with MAS in either response group while in the sitting position, but in the supine position NAR increased significantly with MAS in the nonresponder group (11.8 ± 1.5 vs 13.8 ± 1.6 cm H2O/L/s; P < 0.01). Logistic regression analysis revealed that NAR and BMI were the most important predictive factors for MAS Treatment Outcome. These data suggest that higher levels of NAR may negatively impact on Treatment Outcome with MAS. Citation: Zeng B; Ng AT; Qian J; Petocz P; Darendeliler MA; Cistulli PA. Influence of nasal resistance on oral appliance Treatment Outcome in obstructive sleep apnea. SLEEP 2008;31(4):543-547.

Biao Zeng - One of the best experts on this subject based on the ideXlab platform.

  • influence of nasal resistance on oral appliance Treatment Outcome in obstructive sleep apnea
    Sleep, 2008
    Co-Authors: Ali M Darendeliler, Peter Petocz, Peter A Cistulli, Biao Zeng, Jin Qian
    Abstract:

    It has been recognized that nasal airway resistance (NAR) is elevated in patients with OSA. However, little is known regarding the influence of nasal resistance on mandibular advancement splint (MAS) Treatment Outcome in OSA patient. We hypothesized that nasal resistance differs between MAS responders and nonresponders and therefore may influence Treatment Outcome. Thirty-eight patients with known OSA underwent polysomnography while wearing a custom-made MAS. Treatment Outcome was defined as follows: Responders (R) ≥50% reduction in AHI, and Nonresponders (NR) as <50% reduction in AHI. NAR was measured using posterior rhinomanometry in both sitting and supine positions, with and without MAS. The mean AHI in 26 responders was significantly reduced from 29.0 ± 2.9/h to 6.7 ± 1.2/h; P < 0.01). In 12 nonresponders there was no significant change in AHI (23.9 ± 3.0/h vs 22.0 ± 4.3/h; P=ns). Baseline NAR was significantly lower in responders in the sitting position compared to nonresponders (6.5 ± 0.5 vs 9.4 ± 1.0cm H2O; P < 0.01). There was no significant change in NAR (from baseline) with MAS in either response group while in the sitting position, but in the supine position NAR increased significantly with MAS in the nonresponder group (11.8 ± 1.5 vs 13.8 ± 1.6 cm H2O/L/s; P < 0.01). Logistic regression analysis revealed that NAR and BMI were the most important predictive factors for MAS Treatment Outcome. These data suggest that higher levels of NAR may negatively impact on Treatment Outcome with MAS. Citation: Zeng B; Ng AT; Qian J; Petocz P; Darendeliler MA; Cistulli PA. Influence of nasal resistance on oral appliance Treatment Outcome in obstructive sleep apnea. SLEEP 2008;31(4):543-547.

Abraham Aseffa - One of the best experts on this subject based on the ideXlab platform.

Ali M Darendeliler - One of the best experts on this subject based on the ideXlab platform.

  • cephalometry and prediction of oral appliance Treatment Outcome
    Sleep and Breathing, 2012
    Co-Authors: Ali M Darendeliler, Peter Petocz, Peter A Cistulli
    Abstract:

    Predicting which patients with obstructive sleep apnea (OSA) will be successfully treated with mandibular advancement splints (MAS) remains elusive. Developing simple daytime measurements and tests to predict Treatment Outcome would enhance MAS Treatment. The purpose of this study was to assess the clinical utility of anthropomorphic measurements and cephalometric X-rays in the prediction of MAS Treatment Outcome in OSA. Anthropomorphic measurements and cephalometric X-rays from 72 OSA patients who had presented to a tertiary referral sleep clinic were analyzed retrospectively. Treatment response was defined as ≥50% reduction in Apnea/Hypopnea Index (AHI; criterion 1); ≥50% reduction and residual AHI less than 20/h (criterion 2); ≥50% reduction in AHI and residual AHI less than 10/h (criterion 3); and ≥50% reduction in AHI and residual AHI less than 5/h (criterion 4). This was done to reflect the differences in the clinical definition of Treatment success in the literature. A good response occurred in 56% (40 patients) according to criterion 1; 54% (39 patients) according to criterion 2; 46% (33 patients) according to criterion 3; or 39% (28 patients) according to criterion 4. Age and gender were found to be significant predictors for criteria 1 and 2. Age and soft palate length were found to be significant predictors for criteria 3 and 4. Equations to predict MAS Treatment response were derived as equations were to predict final AHI. Certain cephalometric and anthropomorphic measurements impact on MAS Treatment Outcome. This study adds to the current literature and implies that MAS success is (to some degree) related to anatomical characteristics.

  • influence of nasal resistance on oral appliance Treatment Outcome in obstructive sleep apnea
    Sleep, 2008
    Co-Authors: Ali M Darendeliler, Peter Petocz, Peter A Cistulli, Biao Zeng, Jin Qian
    Abstract:

    It has been recognized that nasal airway resistance (NAR) is elevated in patients with OSA. However, little is known regarding the influence of nasal resistance on mandibular advancement splint (MAS) Treatment Outcome in OSA patient. We hypothesized that nasal resistance differs between MAS responders and nonresponders and therefore may influence Treatment Outcome. Thirty-eight patients with known OSA underwent polysomnography while wearing a custom-made MAS. Treatment Outcome was defined as follows: Responders (R) ≥50% reduction in AHI, and Nonresponders (NR) as <50% reduction in AHI. NAR was measured using posterior rhinomanometry in both sitting and supine positions, with and without MAS. The mean AHI in 26 responders was significantly reduced from 29.0 ± 2.9/h to 6.7 ± 1.2/h; P < 0.01). In 12 nonresponders there was no significant change in AHI (23.9 ± 3.0/h vs 22.0 ± 4.3/h; P=ns). Baseline NAR was significantly lower in responders in the sitting position compared to nonresponders (6.5 ± 0.5 vs 9.4 ± 1.0cm H2O; P < 0.01). There was no significant change in NAR (from baseline) with MAS in either response group while in the sitting position, but in the supine position NAR increased significantly with MAS in the nonresponder group (11.8 ± 1.5 vs 13.8 ± 1.6 cm H2O/L/s; P < 0.01). Logistic regression analysis revealed that NAR and BMI were the most important predictive factors for MAS Treatment Outcome. These data suggest that higher levels of NAR may negatively impact on Treatment Outcome with MAS. Citation: Zeng B; Ng AT; Qian J; Petocz P; Darendeliler MA; Cistulli PA. Influence of nasal resistance on oral appliance Treatment Outcome in obstructive sleep apnea. SLEEP 2008;31(4):543-547.

Thomas H. Mcglashan - One of the best experts on this subject based on the ideXlab platform.

  • Treatment Outcome of personality disorders
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1998
    Co-Authors: Charles A. Sanislow, Thomas H. Mcglashan
    Abstract:

    Objective:To review the Treatment Outcome of personality disorders.Method:A literature search of studies pertaining to personality disorder and Outcome was conducted, and studies that focused primarily on Axis II were retained. Of these, naturalistic Outcome studies were distinguished from those that addressed Treatment Outcome specifically. The Treatment Outcome studies were examined in terms of type of Treatment intervention, dependent variables, and Outcome.Results:Contrary to contemporary assumptions about Axis II, a substantial number of Treatment Outcome studies were identified. Trends in the assumptions underlying psychosocial and pharmacologic approaches were identified on the basis of dependent variables.Conclusion:There is evidence that effective Treatments exist to alleviate symptoms and reduce symptomatic behaviours that accompany personality disorders. What these results hold for the idea of remission from personality disorder is considered.