The Experts below are selected from a list of 38364 Experts worldwide ranked by ideXlab platform
Samuel Swishermcclure - One of the best experts on this subject based on the ideXlab platform.
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the impact of Treatment Package time on locoregional control for hpv oropharyngeal squamous cell carcinoma treated with surgery and postoperative chemo radiation
Head and Neck-journal for The Sciences and Specialties of The Head and Neck, 2019Co-Authors: Hannhsiang Chao, Samuel Swishermcclure, Ara A Chalian, Gregory S Weinstein, Caitlin A Schonewolf, Erik X Tan, Alireza Fotouhi Ghiam, Bert W Omalley, Christopher H Rassekh, Jason G NewmanAbstract:Background For patients with head and neck squamous cell carcinoma (SCC) undergoing surgery followed by postoperative radiotherapy (PORT), time from surgery to completion of adjuvant therapy, "Package time" impacts locoregional control (LRC). However, the significance of Package time in HPV+ oropharyngeal SCC (OPSCC) is unknown. Methods We examined patients undergoing TORS resection with PORT for HPV+ OPSCC from January 2010 to December 2015 with ≥18 months follow-up (n = 267). A cutoff of 15 weeks was used to delineate patients into short and long Package time groups. LRC loss was defined as any recurrence after surgery. Results Prolonged Package time >15 weeks was associated with inferior LRC in this HPV+ OPSCC cohort, driven primarily by interval from surgery to PORT initiation. Multivariate analysis showed that Package time and T classification are both independently associated with LRC. Conclusions Among HPV+ OPSCC, prolongation of Package time appears to compromise LRC, but not survival.
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national disparities in Treatment Package time for resected locally advanced head and neck cancer and impact on overall survival
Head and Neck-journal for The Sciences and Specialties of The Head and Neck, 2018Co-Authors: David M Guttmann, Julie Kobie, Surbhi Grover, Alexander Lin, John N Lukens, Nandita Mitra, Karin V Rhodes, Weiwei Feng, Samuel SwishermcclureAbstract:BACKGROUND The purpose of this study was to determine national disparities in head and neck cancer Treatment Package time (the time interval from surgery through the completion of radiation) and the associated impact on survival. METHODS We conducted an observational cohort study using the National Cancer Database of 15 234 patients with resected head and neck cancer who underwent adjuvant radiotherapy from 2004-2012. Predictors of prolonged Package time were identified by multivariable linear regression. Survival outcomes were assessed using a multivariable Cox model. RESULTS Mean Package time was 100 days (SD 23). Package time was 7.52 days (95% confidence interval [CI] 6.23-8.81; P < .001) longer with Medicaid versus commercial insurance. Low income and African American race also predicted for longer Package times. All-cause mortality increased an average of 4% with each 1 week increase in Treatment Package time (hazard ratio [HR] 1.04; 95% CI 1.03-1.05; P < .001). CONCLUSION Significant national socioeconomic disparities exist in Treatment Package time. Treatment delays in this setting may contribute to worse survival outcomes.
R. Biemond - One of the best experts on this subject based on the ideXlab platform.
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Virtual reality exposure therapy of anxiety disorders: a review.
Clinical Psychology Review, 2004Co-Authors: M. Krijn, R. P. Olafsson, Paul Maria Gerardus Emmelkamp, R. BiemondAbstract:Abstract Virtual reality exposure therapy (VRET) is an altered form of behavioral therapy and may be a possible alternative to standard in vivo exposure. Virtual reality integrates real-time computer graphics, body tracking devices, visual displays, and other sensory input devices to immerse patients in a computer-generated virtual environment. Research on this type of Treatment for anxiety disorders is discussed in this article, and the mediating and moderating variables that influence VR Treatment effectiveness as well. Evidence is found that VRET is effective for participants with fear of heights and of flying. For other phobias, research to date is not conclusive. More randomized clinical trials in which VRET is compared with standard exposure are required. Furthermore, studies are needed in which VRET is not just a component of the Treatment Package evaluated, but in which VRET should be assessed as a stand-alone Treatment.
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review articlevirtual reality exposure therapy of anxiety disorders a review
Clinical Psychology Review, 2004Co-Authors: M. Krijn, R. P. Olafsson, Paul Maria Gerardus Emmelkamp, R. BiemondAbstract:Virtual reality exposure therapy (VRET) is an altered form of behavioral therapy and may be a possible alternative to standard in vivo exposure. Virtual reality integrates real-time computer graphics, body tracking devices, visual displays, and other sensory input devices to immerse patients in a computer-generated virtual environment. Research on this type of Treatment for anxiety disorders is discussed in this article, and the mediating and moderating variables that influence VR Treatment effectiveness as well. Evidence is found that VRET is effective for participants with fear of heights and of flying. For other phobias, research to date is not conclusive. More randomized clinical trials in which VRET is compared with standard exposure are required. Furthermore, studies are needed in which VRET is not just a component of the Treatment Package evaluated, but in which VRET should be assessed as a stand-alone Treatment.
Jeanmarie Boisvert - One of the best experts on this subject based on the ideXlab platform.
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cognitive and behavioral Treatment of pathological gambling a controlled study
Journal of Consulting and Clinical Psychology, 1997Co-Authors: Caroline Sylvain, Robert Ladouceur, Jeanmarie BoisvertAbstract:This study evaluated the efficacy of a cognitive-behavioral Treatment Package for pathological gambling. Twenty-nine men who met criteria for pathological gambling in accordance with the Diagnostic and Statistical Manual of Mental Disorders (3rd ed., revised; DSM-III-R; American Psychiatric Association, 1987) were randomly assigned to Treatment or wait-list control. The Treatment included 4 components: (a) cognitive correction of erroneous perceptions about gambling, (b) problem-solving training, (c) social skills training, and (d) relapse prevention. The dependent variables were the South Oaks Gambling Screen, perception of control, frequency of gambling, perceived self-efficacy, desire to gamble, and number of DSM-III-R criteria met by participants. Posttest results indicated highly significant changes in the Treatment group on all outcome measures, and analysis of data from 6- and 12-month follow-ups revealed maintenance of therapeutic gains. Recommendations for clinical interventions are discussed and focus on the cognitive correction of erroneous perceptions of gambling.
Dorothy Scattone - One of the best experts on this subject based on the ideXlab platform.
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enhancing the conversation skills of a boy with asperger s disorder through social stories and video modeling
Journal of Autism and Developmental Disorders, 2008Co-Authors: Dorothy ScattoneAbstract:This study combined Social Stories with video modeling in an effort to enhance the conversation skills of a boy with Asperger's Disorder. Treatment consisted of two components: (a) observation of video taped Social Stories that included two adults modeling targeted conversational skills and (b) 5-min social interactions. A multiple baseline design across behaviors was used to evaluate the intervention and an increase in 2 out of 3 targeted conversation skills occurred. In addition, generalized behavior changes were observed. These findings provide support for including Social Stories as part of a video Treatment Package in teaching complex social interaction behaviors to young children with Asperger's Disorder.
Dustin P Wallace - One of the best experts on this subject based on the ideXlab platform.
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evaluation of a behavioral Treatment Package to reduce sleep problems in children with angelman syndrome
Research in Developmental Disabilities, 2013Co-Authors: Keith D Allen, Brett R Kuhn, Kristi Dehaai, Dustin P WallaceAbstract:The purpose of this investigation was to evaluate the effectiveness of a behavioral Treatment Package to reduce chronic sleep problems in children with Angelman Syndrome. Participants were five children, 2-11 years-of-age. Parents maintained sleep diaries to record sleep and disruptive nighttime behaviors. Actigraphy was added to provide independent evaluations of sleep-wake activity. The Treatment Package targeted the sleep environment, the sleep-wake schedule, and parent-child interactions during sleep times. Treatment was introduced sequentially, across families, and evaluated in an interrupted time series, multiple baseline design. Data show that prior to Treatment, baseline rates of nighttime disruptive behavior were stable or increasing and none of the participants were falling to sleep independently. With the introduction of Treatment, all participants quickly learned to initiate sleep independently. Gradual reductions were reported in disruptive behaviors and these improvements were sustained over time. Results were replicated with two participants when Treatment was withdrawn and reinstated. Changes in disruptive bedtime behaviors and in sleep onset were found to be statistically significant. Parents indicated high satisfaction with the Treatment. A behavioral Treatment Package was found to be effective with five children with long histories of significant sleep-related behavior problems. These results suggest that behavioral Treatment may be a reasonable way to address sleep problems in some children with Angelman Syndrome.
