The Experts below are selected from a list of 399 Experts worldwide ranked by ideXlab platform
Mohammad Ali Zolfigol - One of the best experts on this subject based on the ideXlab platform.
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Trichloroisocyanuric Acid (TCCA) as a mild and efficient catalyst for the trimethylsilylation of alcohols and phenols with hexamethyldisilazane (HMDS) under heterogonous conditions
Catalysis Communications, 2007Co-Authors: Ardeshir Khazaei, Amin Rostami, Mohammad Ali Zolfigol, Arash Ghorbani ChoghamaraniAbstract:Abstract A novel and efficient method for the trimethylsilylation of various alcohols and phenols with hexamethyldisilazane (HMDS) catalyzed by Trichloroisocyanuric Acid (TCCA) in good to excellent yields in dichloromethane at room temperature was described.
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acylation of alcohols catalyzed by using 1 3 dibromo 5 5 dimethylhydentoin or Trichloroisocyanuric Acid
Catalysis Communications, 2006Co-Authors: Mohammad Ali Zolfigol, Ardeshir Khazaei, Amin Rostami, Arash Ghorbani Choghamarani, Maryam HajjamiAbstract:Abstract An efficient method for the acylation of alcohols by using acetic anhydride and a catalytic amounts of 1,3-dibromo-5,5-dimethylhydantoin and/or Trichloroisocyanuric Acid under mild and heterogeneous conditions at room temperature described in good to excellent yields.
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Trichloroisocyanuric Acid kbr as a catalytic system for the chemoselective oxidation of benzylic and secondary alcohols
Synthesis, 2006Co-Authors: Mohammad Ali Zolfigol, Farhad Shirini, Arash Ghorbani ChoghamaraniAbstract:Chemoselective oxidation of benzylic and secondary al- cohols were proceeded by using a catalytic amount of KBr in the presence of Trichloroisocyanuric Acid and wet SiO2 under mild and heterogeneous conditions with excellent yields.
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novel mild and chemoselective dehydrogenation of 2 imidazolines with Trichloroisocyanuric Acid
Synlett, 2004Co-Authors: Iraj Mohammadpoorbaltork, Mohammad Ali Zolfigol, Mohammad AbdollahialibeikAbstract:A rapid, mild and high-yielding method for dehydrogenation of a variety of structurally diverse 2-imidazolines to imidazoles using Trichloroisocyanuric Acid (TCCA) in the presence of DBU is reported. Chemoselective oxidation of 2-imidazolines can be achieved in the presence of sulfide and alcohol. The mild conditions of this procedure and the absence of any transition metal make this reaction suitable for safe laboratory use.
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Trichloroisocyanuric Acid as a novel oxidizing agent for the oxidation of 1 3 5 trisubstituted pyrazolines under both heterogeneous and solvent free conditions
Tetrahedron Letters, 2004Co-Authors: Mohammad Ali Zolfigol, Davood Azarifar, Behrooz MalekiAbstract:Trichloroisocyanuric Acid is used as an effective oxidizing agent for the oxidation of 1,3,5-trisubstituted pyrazolines to their corresponding pyrazoles under both heterogeneous and also solvent free conditions with good yields at room temperature.
Danfeng Huang - One of the best experts on this subject based on the ideXlab platform.
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synthesis of trifluoroethyl pyrazolines via Trichloroisocyanuric Acid promoted cascade cyclization trifluoromethylation of β γ unsaturated hydrazones
Journal of Organic Chemistry, 2018Co-Authors: Bingbing Chang, Weigang Zhang, Kehu Wang, Ya Shi, Danfeng Huang, Xinghu ZhangAbstract:A novel and efficient protocol for the construction of trifluoroethyl pyrazolines has been developed by cascade cyclization/trifluoromethylation reaction of β,γ-unsaturated hydrazones. This strategy uses cheap and commercially available Trichloroisocyanuric Acid as promoter and TMSCF3 as the trifluoromethylating reagent, which make the trifluoromethylating process much cheaper. A wide range of substrates can be applied in this process to afford the trifluoroethyl pyrazolines in good yield.
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Synthesis of Trifluoroethyl Pyrazolines via Trichloroisocyanuric Acid Promoted Cascade Cyclization/Trifluoromethylation of β,γ‑Unsaturated Hydrazones
2018Co-Authors: Bingbing Chang, Weigang Zhang, Kehu Wang, Ya Shi, Danfeng Huang, Xinghu ZhangAbstract:A novel and efficient protocol for the construction of trifluoroethyl pyrazolines has been developed by cascade cyclization/trifluoromethylation reaction of β,γ-unsaturated hydrazones. This strategy uses cheap and commercially available Trichloroisocyanuric Acid as promoter and TMSCF3 as the trifluoromethylating reagent, which make the trifluoromethylating process much cheaper. A wide range of substrates can be applied in this process to afford the trifluoroethyl pyrazolines in good yield
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Trichloroisocyanuric Acid promoted cascade cyclization trifluoromethylation of allylic oximes synthesis of trifluoromethylated isoxazolines
Organic Letters, 2017Co-Authors: Weigang Zhang, Kehu Wang, Bingbing Chang, Ya Shi, Danfeng HuangAbstract:Cheap and commercially available Trichloroisocyanuric Acid has been used to promote trifluoromethylation by using TMSCF3 as the trifluoromethyl source. The method provides a novel and efficient protocol for the construction of CF3-containing 4,5-dihydroisoxazoles from allylic oximes in good to excellent yields.
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Trichloroisocyanuric Acid Promoted Cascade Cyclization/Trifluoromethylation of Allylic Oximes: Synthesis of Trifluoromethylated Isoxazolines
2017Co-Authors: Weigang Zhang, Kehu Wang, Bingbing Chang, Ya Shi, Danfeng HuangAbstract:Cheap and commercially available Trichloroisocyanuric Acid has been used to promote trifluoromethylation by using TMSCF3 as the trifluoromethyl source. The method provides a novel and efficient protocol for the construction of CF3-containing 4,5-dihydroisoxazoles from allylic oximes in good to excellent yields
Hua Yang - One of the best experts on this subject based on the ideXlab platform.
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enantiospecific total synthesis of tanikolide via a key 2 3 meisenheimer rearrangement with an allylic amine n oxide directed epoxidation and a one pot Trichloroisocyanuric Acid n debenzylation and n chlorination
Journal of Organic Chemistry, 2013Co-Authors: Yangla Xie, Moran Sun, Hang Zhou, Qiwei Cao, Kaige Gao, Changling Niu, Hua YangAbstract:The enantiospecific total synthesis of the δ-lactonic marine natural product (+)-tanikolide (1), isolated from Lyngbya majuscula , was achieved using a [2,3]-Meisenheimer rearrangement as the key reaction. During this rearrangement, we discovered that the allylic amine N-oxide could direct the m-CPBA double-bond epoxidation to the syn position. The resulting syn product 8 underwent epoxide ring opening under the m-CBA conditions to give the five- and six-membered cyclic ether amine N-oxides, which we further treated with Zn and conc. HCl to obtain the reduced bisbenzyl tertiary amines 23 and 22, respectively. When 23 and 22 were treated with Trichloroisocyanuric Acid (TCCA) in dichloromethane, oxidation at the benzyl position occurred, forming iminium ions. These intermediates were trapped by intramolecular reaction with the hydroxyls, and the resulting intermediates were then oxidized or shifted to afford 25 and 24, respectively. The entire one-pot process involves N-debenzylation, N-chlorination, and hemiacetal oxidation. The amine N-oxide-directed epoxidation complements Davies' ammonium-directed epoxidation. Thus, TCCA N-debenzylation is described for the first time and might be a useful N-debenzylation technique.
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Enantiospecific Total Synthesis of (+)-Tanikolide via a Key [2,3]-Meisenheimer Rearrangement with an Allylic Amine N‑Oxide-Directed Epoxidation and a One-Pot Trichloroisocyanuric Acid N‑Debenzylation and N‑Chlorination
2013Co-Authors: Yangla Xie, Moran Sun, Hang Zhou, Qiwei Cao, Kaige Gao, Changling Niu, Hua YangAbstract:The enantiospecific total synthesis of the δ-lactonic marine natural product (+)-tanikolide (1), isolated from Lyngbya majuscula, was achieved using a [2,3]-Meisenheimer rearrangement as the key reaction. During this rearrangement, we discovered that the allylic amine N-oxide could direct the m-CPBA double-bond epoxidation to the syn position. The resulting syn product 8 underwent epoxide ring opening under the m-CBA conditions to give the five- and six-membered cyclic ether amine N-oxides, which we further treated with Zn and conc. HCl to obtain the reduced bisbenzyl tertiary amines 23 and 22, respectively. When 23 and 22 were treated with Trichloroisocyanuric Acid (TCCA) in dichloromethane, oxidation at the benzyl position occurred, forming iminium ions. These intermediates were trapped by intramolecular reaction with the hydroxyls, and the resulting intermediates were then oxidized or shifted to afford 25 and 24, respectively. The entire one-pot process involves N-debenzylation, N-chlorination, and hemiacetal oxidation. The amine N-oxide-directed epoxidation complements Davies’ ammonium-directed epoxidation. Thus, TCCA N-debenzylation is described for the first time and might be a useful N-debenzylation technique
Weigang Zhang - One of the best experts on this subject based on the ideXlab platform.
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synthesis of trifluoroethyl pyrazolines via Trichloroisocyanuric Acid promoted cascade cyclization trifluoromethylation of β γ unsaturated hydrazones
Journal of Organic Chemistry, 2018Co-Authors: Bingbing Chang, Weigang Zhang, Kehu Wang, Ya Shi, Danfeng Huang, Xinghu ZhangAbstract:A novel and efficient protocol for the construction of trifluoroethyl pyrazolines has been developed by cascade cyclization/trifluoromethylation reaction of β,γ-unsaturated hydrazones. This strategy uses cheap and commercially available Trichloroisocyanuric Acid as promoter and TMSCF3 as the trifluoromethylating reagent, which make the trifluoromethylating process much cheaper. A wide range of substrates can be applied in this process to afford the trifluoroethyl pyrazolines in good yield.
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Synthesis of Trifluoroethyl Pyrazolines via Trichloroisocyanuric Acid Promoted Cascade Cyclization/Trifluoromethylation of β,γ‑Unsaturated Hydrazones
2018Co-Authors: Bingbing Chang, Weigang Zhang, Kehu Wang, Ya Shi, Danfeng Huang, Xinghu ZhangAbstract:A novel and efficient protocol for the construction of trifluoroethyl pyrazolines has been developed by cascade cyclization/trifluoromethylation reaction of β,γ-unsaturated hydrazones. This strategy uses cheap and commercially available Trichloroisocyanuric Acid as promoter and TMSCF3 as the trifluoromethylating reagent, which make the trifluoromethylating process much cheaper. A wide range of substrates can be applied in this process to afford the trifluoroethyl pyrazolines in good yield
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Trichloroisocyanuric Acid promoted cascade cyclization trifluoromethylation of allylic oximes synthesis of trifluoromethylated isoxazolines
Organic Letters, 2017Co-Authors: Weigang Zhang, Kehu Wang, Bingbing Chang, Ya Shi, Danfeng HuangAbstract:Cheap and commercially available Trichloroisocyanuric Acid has been used to promote trifluoromethylation by using TMSCF3 as the trifluoromethyl source. The method provides a novel and efficient protocol for the construction of CF3-containing 4,5-dihydroisoxazoles from allylic oximes in good to excellent yields.
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Trichloroisocyanuric Acid Promoted Cascade Cyclization/Trifluoromethylation of Allylic Oximes: Synthesis of Trifluoromethylated Isoxazolines
2017Co-Authors: Weigang Zhang, Kehu Wang, Bingbing Chang, Ya Shi, Danfeng HuangAbstract:Cheap and commercially available Trichloroisocyanuric Acid has been used to promote trifluoromethylation by using TMSCF3 as the trifluoromethyl source. The method provides a novel and efficient protocol for the construction of CF3-containing 4,5-dihydroisoxazoles from allylic oximes in good to excellent yields
Bingbing Chang - One of the best experts on this subject based on the ideXlab platform.
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synthesis of trifluoroethyl pyrazolines via Trichloroisocyanuric Acid promoted cascade cyclization trifluoromethylation of β γ unsaturated hydrazones
Journal of Organic Chemistry, 2018Co-Authors: Bingbing Chang, Weigang Zhang, Kehu Wang, Ya Shi, Danfeng Huang, Xinghu ZhangAbstract:A novel and efficient protocol for the construction of trifluoroethyl pyrazolines has been developed by cascade cyclization/trifluoromethylation reaction of β,γ-unsaturated hydrazones. This strategy uses cheap and commercially available Trichloroisocyanuric Acid as promoter and TMSCF3 as the trifluoromethylating reagent, which make the trifluoromethylating process much cheaper. A wide range of substrates can be applied in this process to afford the trifluoroethyl pyrazolines in good yield.
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Synthesis of Trifluoroethyl Pyrazolines via Trichloroisocyanuric Acid Promoted Cascade Cyclization/Trifluoromethylation of β,γ‑Unsaturated Hydrazones
2018Co-Authors: Bingbing Chang, Weigang Zhang, Kehu Wang, Ya Shi, Danfeng Huang, Xinghu ZhangAbstract:A novel and efficient protocol for the construction of trifluoroethyl pyrazolines has been developed by cascade cyclization/trifluoromethylation reaction of β,γ-unsaturated hydrazones. This strategy uses cheap and commercially available Trichloroisocyanuric Acid as promoter and TMSCF3 as the trifluoromethylating reagent, which make the trifluoromethylating process much cheaper. A wide range of substrates can be applied in this process to afford the trifluoroethyl pyrazolines in good yield
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Trichloroisocyanuric Acid promoted cascade cyclization trifluoromethylation of allylic oximes synthesis of trifluoromethylated isoxazolines
Organic Letters, 2017Co-Authors: Weigang Zhang, Kehu Wang, Bingbing Chang, Ya Shi, Danfeng HuangAbstract:Cheap and commercially available Trichloroisocyanuric Acid has been used to promote trifluoromethylation by using TMSCF3 as the trifluoromethyl source. The method provides a novel and efficient protocol for the construction of CF3-containing 4,5-dihydroisoxazoles from allylic oximes in good to excellent yields.
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Trichloroisocyanuric Acid Promoted Cascade Cyclization/Trifluoromethylation of Allylic Oximes: Synthesis of Trifluoromethylated Isoxazolines
2017Co-Authors: Weigang Zhang, Kehu Wang, Bingbing Chang, Ya Shi, Danfeng HuangAbstract:Cheap and commercially available Trichloroisocyanuric Acid has been used to promote trifluoromethylation by using TMSCF3 as the trifluoromethyl source. The method provides a novel and efficient protocol for the construction of CF3-containing 4,5-dihydroisoxazoles from allylic oximes in good to excellent yields
