Tricuspid Valve

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Rebecca T Hahn - One of the best experts on this subject based on the ideXlab platform.

  • Transcatheter treatments for Tricuspid Valve diseases
    Emerging Technologies for Heart Diseases, 2020
    Co-Authors: Nadira Hamid, Rebecca T Hahn
    Abstract:

    Abstract Tricuspid Valve regurgitation (TR) affects as many as 1.2% to 1.5% of the general population, and is linked to increased mortality whether it is isolated or associated with concomitant valvular disease. The high operative mortality for isolated Tricuspid Valve surgery is related to the multiple co-morbidities and cardiac consequences of more advanced disease resulting from late surgical referral or prior left heart surgery. Transcatheter Tricuspid Valve devices thus may play a significant role in the treatment of advanced TR. This chapter provides a review of the current transcatheter Tricuspid Valve therapies with a discussion of future challenges and opportunities.

  • Tricuspid Valve Disease
    Heart Valve Disease, 2019
    Co-Authors: Rebecca T Hahn
    Abstract:

    Increasing interest in the Tricuspid Valve has been stimulated by numerous outcomes studies showing the significant role of Tricuspid regurgitation (TR) on outcomes. Primary TR represents a small number of the patients presenting with symptomatic disease. Understanding of the anatomy of the right heart and Tricuspid Valve helps elucidate the multiple mechanisms that result in secondary TR. Echocardiography remains a primary imaging modality for the assessment of disease morphology and severity.

  • Anatomy and Physiology of the Tricuspid Valve
    JACC. Cardiovascular imaging, 2019
    Co-Authors: Abdellaziz Dahou, Dmitry Levin, Mark Reisman, Rebecca T Hahn
    Abstract:

    Summary An appreciation of the complex and variable anatomy of the Tricuspid Valve is essential to unraveling the pathophysiology of Tricuspid regurgitation. A greater appreciation of normal and abnormal anatomy is important as new methods of treating the Tricuspid regurgitation are developed. This review of Tricuspid Valve and right heart anatomy is followed by a discussion of the possible pathophysiology of secondary (functional) Tricuspid regurgitation.

  • Imaging of the Tricuspid Valve: Transoesophageal Echocardiography
    Practical Manual of Tricuspid Valve Diseases, 2018
    Co-Authors: Rebecca T Hahn
    Abstract:

    The presence of functional TR, either isolated or in combination with left heart disease is associated with unfavorable natural history. In addition, mortality for isolated Tricuspid Valve interventions remain higher than for any other single Valve surgery. Finally, as more left sided Valve disease is treated with transcatheter therapies the need for transcatheter solutions to functional Tricuspid regurgitation. Transesophageal echocardiographic (TOE) imaging of the Tricuspid Valve has become an important intra-procedural tool for assessing the morphology of the Valve apparatus and severity of disease, guiding transcatheter solutions and assessing the results of interventions. The following chapter reviews the Tricuspid Valve anatomy and essential TOE views to define this anatomy and valvular function.

  • First-in-human transcatheter Tricuspid Valve repair in a patient with severely regurgitant Tricuspid Valve
    Journal of the American College of Cardiology, 2015
    Co-Authors: Joachim Schofer, Klaudija Bijuklic, Claudia Tiburtius, Lorenz Hansen, Adam Groothuis, Rebecca T Hahn
    Abstract:

    Background Severe Tricuspid regurgitation is associated with poor prognosis; however, there are limited Class I indications for intervention, and high-surgical risk patients may go untreated. We report the first-in-human successful transcatheter Tricuspid Valve repair for severe Tricuspid regurgitation. Objectives The objective of this study was to show the feasibility of a transcatheter Tricuspid annular repair. Methods Compassionate-use approval for the procedure was obtained from the regulatory organization in Germany. To perform the transcatheter bicuspidization of the Tricuspid Valve, the Mitralign system was used to place pledgeted sutures by means of a trans-jugular venous approach. Insulated radiofrequency wires were positioned 2 to 5 mm from the base of the posterior leaflet, 2.6 cm apart. The sutures were drawn together and locked, plicating the posterior annulus. Results Reconstruction of the 3-dimensional transesophageal echocardiographic dataset at baseline revealed a Tricuspid Valve annular area of 14.1 cm2, and effective regurgitant orifice area was 1.35 cm2. There was a significant reduction in annular area (57%) and effective regurgitant orifice area (53%) measured with 3-dimensional transesophageal echocardiography, at 6.05 cm2and 0.63 cm2, respectively. Hemodynamic parameters also improved with a reduction in right atrial pressure from 22 mm Hg at baseline, to 9 mm Hg and an increase in left ventricular stroke volume from 42 ml at baseline to 72 ml. Conclusions Transcatheter Tricuspid Valve repair could become an effective treatment for high-surgical risk patients who are non-responsive to optimal medical therapy.

Joe W.r. Bolton - One of the best experts on this subject based on the ideXlab platform.

Joachim Schofer - One of the best experts on this subject based on the ideXlab platform.

  • First-in-human transcatheter Tricuspid Valve repair in a patient with severely regurgitant Tricuspid Valve
    Journal of the American College of Cardiology, 2015
    Co-Authors: Joachim Schofer, Klaudija Bijuklic, Claudia Tiburtius, Lorenz Hansen, Adam Groothuis, Rebecca T Hahn
    Abstract:

    Background Severe Tricuspid regurgitation is associated with poor prognosis; however, there are limited Class I indications for intervention, and high-surgical risk patients may go untreated. We report the first-in-human successful transcatheter Tricuspid Valve repair for severe Tricuspid regurgitation. Objectives The objective of this study was to show the feasibility of a transcatheter Tricuspid annular repair. Methods Compassionate-use approval for the procedure was obtained from the regulatory organization in Germany. To perform the transcatheter bicuspidization of the Tricuspid Valve, the Mitralign system was used to place pledgeted sutures by means of a trans-jugular venous approach. Insulated radiofrequency wires were positioned 2 to 5 mm from the base of the posterior leaflet, 2.6 cm apart. The sutures were drawn together and locked, plicating the posterior annulus. Results Reconstruction of the 3-dimensional transesophageal echocardiographic dataset at baseline revealed a Tricuspid Valve annular area of 14.1 cm2, and effective regurgitant orifice area was 1.35 cm2. There was a significant reduction in annular area (57%) and effective regurgitant orifice area (53%) measured with 3-dimensional transesophageal echocardiography, at 6.05 cm2and 0.63 cm2, respectively. Hemodynamic parameters also improved with a reduction in right atrial pressure from 22 mm Hg at baseline, to 9 mm Hg and an increase in left ventricular stroke volume from 42 ml at baseline to 72 ml. Conclusions Transcatheter Tricuspid Valve repair could become an effective treatment for high-surgical risk patients who are non-responsive to optimal medical therapy.

Volkmar Falk - One of the best experts on this subject based on the ideXlab platform.

  • Tricuspid Valve interventions: surgical techniques and outcomes.
    EuroIntervention, 2015
    Co-Authors: Christoph Starck, Jörg Kempfert, Volkmar Falk
    Abstract:

    The surgical treatment of isolated and concomitant Tricuspid Valve disease, especially functional Tricuspid Valve regurgitation, remains controversial. Functional Tricuspid regurgitation may be classified into defined stages, and surgical treatment may be tailored to the extent of the disease. This report describes current surgical techniques for Tricuspid Valve surgery and their results.

  • Stentless Tricuspid Valve replacement
    The Annals of thoracic surgery, 1999
    Co-Authors: Thomas Walther, Volkmar Falk, Johannes Schneider, Claudia Walther, Friedrich W. Mohr
    Abstract:

    Stentless Tricuspid Valve replacement was performed in a 21-year-old patient with severe destructive Tricuspid Valve endocarditis resistant to medical therapy. Postoperative recovery was uneventful. Stentless atrioventricular Valves are considered an additional treatment option besides stented Valves or homograft implantations for severe right-sided endocarditis. Transvalvular hemodynamics are excellent, and right ventricular function can be preserved by suspending the Valve at the papillary muscles.

Massimo Chessa - One of the best experts on this subject based on the ideXlab platform.

  • Tricuspid Valve Injury After Surgical/Transcatheter Procedures
    The Tricuspid Valve in Congenital Heart Disease, 2014
    Co-Authors: Alessandro Giamberti, Massimo Chessa
    Abstract:

    Tricuspid Valve injury may be a complication of both a surgical and a transcatheter procedure. Surgical injury of the Tricuspid Valve is a quite uncommon complication that has been mainly associated with ventricular septal defect closure, partial or complete atrioventricular septal defect repair, and tetralogy of Fallot repair. Tricuspid Valve injuries are described as a non-frequent complication of a cardiac catheterization and may occur as a result of chorda tendinea lesion during a pulmonary artery catheterization or as a consequence of ventricular septal defect device closure. The management and indication to treat these lesions remain controversial. The purpose of this chapter is to consider the possible causes of Tricuspid Valve injuries and how and when to treat these complications.

  • Transcatheter Treatment of Tricuspid Valve
    The Tricuspid Valve in Congenital Heart Disease, 2014
    Co-Authors: Massimo Chessa, Luca Giugno, Gianfranco Butera, Mario Carminati
    Abstract:

    Tricuspid Valve replacement is not a common operation and, in most series, is associated with high postoperative mortality. Although bioprosthetic Valves appear to have improved the performance early after surgery, these Valves will inevitably experience wear and degeneration, requiring a second implant. Redo Valve surgery for bioprosthetic Valve failure is challenging. In this context, there has been an understandable interest in percutaneous Valve therapy to extend the life span of failing Tricuspid Valve prostheses.