The Experts below are selected from a list of 366 Experts worldwide ranked by ideXlab platform
Bruce R Russell - One of the best experts on this subject based on the ideXlab platform.
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investigation of the effects of piperazine containing party pills and dexamphetamine on interhemispheric communication using electroencephalography
Psychopharmacology, 2016Co-Authors: Grace Y. Wang, Louise E Curley, Ian J Kirk, Robert R Kydd, Bruce R RussellAbstract:Background ‘Piperazine-containing party pills’ were marketed and sold as legal alternatives to methamphetamine and 3,4-methylenedioxymethamphetamine (MDMA) until 2008 in New Zealand. The major constituents of these ‘pills’ were benzylphenylpiperazine (BZP) and Trifluoromethylphenylpiperazine (TFMPP). Despite their popularity, there is a paucity of knowledge about their central effects in humans. This study investigated their effects on human neural processing using electroencephalographic techniques.
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Acute effects of BZP, TFMPP and the combination of BZP and TFMPP in comparison to dexamphetamine on an auditory oddball task using electroencephalography: a single-dose study
Psychopharmacology, 2016Co-Authors: Grace Y. Wang, Louise E Curley, Ian J Kirk, John J. Sollers, Robert R Kydd, Bruce R RussellAbstract:Rationale Piperazine-based designer drugs such as benzylpiperazine (BZP) and Trifluoromethylphenylpiperazine (TFMPP) have been marketed and sold as legal alternatives to dexamphetamine and 3,4-methylenedioxymethamphetamine (MDMA) until 2008 in New Zealand. When administered in combination, BZP + TFMPP have been reported to produce drug-drug synergism in rodents by stimulating the release of dopamine and serotonin. Objectives This study was to evaluate the acute event-related potential effects of BZP, TFMPP or the combination of BZP + TFMPP compared with dexamphetamine in young healthy male adults. Methods A double-blind, randomised, placebo-controlled study investigated the effects of BZP, TFMPP, the combination of BZP + TFMPP, and dexamphetamine on the event-related potentials during an auditory oddball task. Healthy, right-handed males were given a single oral dose of either BZP (200 mg), TFMPP (60 mg), a combination of BZP + TFMPP (100/30 mg), dexamphetamine (20 mg) or placebo (lactose) and tested both before and 120 min after drug administration. Results A single dose of either TMFPP ( t = −2.29, p = 0.03) or dexamphetamine ( t = −2.33, p = 0.02) significantly reduced the P300 amplitude. A similar trend was also found in BZP. In contrast, BZP and TFMPP in combination has no effect. Neither P300 latency nor the mean reaction time was affected by any of the drug treatments. In addition, neither the P100 nor the P200 component was significantly affected following any of the drug treatments. Conclusions A single oral dose of BZP or TFMPP, but not the combination of BZP/TFMPP, affected auditory sensory-evoked P300 potential in a manner similar to dexamphetamine.
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acute effects of bzp tfmpp and the combination of bzp and tfmpp in comparison to dexamphetamine on an auditory oddball task using electroencephalography a single dose study
Psychopharmacology, 2016Co-Authors: Grace Y. Wang, Louise E Curley, Ian J Kirk, John J. Sollers, Robert R Kydd, Bruce R RussellAbstract:Rationale Piperazine-based designer drugs such as benzylpiperazine (BZP) and Trifluoromethylphenylpiperazine (TFMPP) have been marketed and sold as legal alternatives to dexamphetamine and 3,4-methylenedioxymethamphetamine (MDMA) until 2008 in New Zealand. When administered in combination, BZP + TFMPP have been reported to produce drug-drug synergism in rodents by stimulating the release of dopamine and serotonin.
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Acute effects of the designer drugs benzylpiperazine (BZP) and Trifluoromethylphenylpiperazine (TFMPP) using functional magnetic resonance imaging (fMRI) and the Stroop task—a pilot study
Psychopharmacology, 2015Co-Authors: Louise E Curley, Ian J Kirk, Robert R Kydd, Michelle C. Robertson, Avinesh Pillai, Nicolas Mcnair, Bruce R RussellAbstract:Rationale A novel group of designer drugs containing benzylpiperazine (BZP) and/or Trifluoromethylphenylpiperazine (TFMPP) have been available worldwide for more than a decade; however, their effects on human brain function have not been extensively described. Objectives In a double-blind, placebo-controlled crossover study, the acute effects of BZP and TFMPP (alone and in combination) on the neural networks involved in executive function were investigated using an event-related Stroop functional magnetic resonance imaging (fMRI) paradigm. Methods Thirteen healthy participants aged 18–40 years undertook the Stroop task 90 min after taking an oral dose of either BZP (200 mg), TFMPP (either 50 or 60 mg), BZP + TFMPP (100 + 30 mg) or placebo. A change in activity in neural regions reflects an increase in local demand for oxygen, due to an increase in neuronal activity. Results Relative to placebo, an increase in neural activation was observed in the dorsal striatum following BZP, and in the thalamus following TFMPP, when performing the Stroop task. Conclusion These data suggest that additional compensatory resources were recruited to maintain performance during the Stroop task. When BZP and TFMPP were administered together, both the dorsal striatum and thalamus were activated. However, the combination of BZP/TFMPP attenuated activation in the caudate, possibly due to TFMPP’s indirect effects on dopamine release via 5HT_2C receptors.
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Acute effects of the designer drugs benzylpiperazine (BZP) and Trifluoromethylphenylpiperazine (TFMPP) using functional magnetic resonance imaging (fMRI) and the Stroop task--a pilot study.
Psychopharmacology, 2015Co-Authors: Louise E Curley, Ian J Kirk, Robert R Kydd, Michelle C. Robertson, Avinesh Pillai, Nicolas A. Mcnair, Heeseung Lee, Bruce R RussellAbstract:Rationale A novel group of designer drugs containing benzylpiperazine (BZP) and/or Trifluoromethylphenylpiperazine (TFMPP) have been available worldwide for more than a decade; however, their effects on human brain function have not been extensively described.
Robert R Kydd - One of the best experts on this subject based on the ideXlab platform.
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investigation of the effects of piperazine containing party pills and dexamphetamine on interhemispheric communication using electroencephalography
Psychopharmacology, 2016Co-Authors: Grace Y. Wang, Louise E Curley, Ian J Kirk, Robert R Kydd, Bruce R RussellAbstract:Background ‘Piperazine-containing party pills’ were marketed and sold as legal alternatives to methamphetamine and 3,4-methylenedioxymethamphetamine (MDMA) until 2008 in New Zealand. The major constituents of these ‘pills’ were benzylphenylpiperazine (BZP) and Trifluoromethylphenylpiperazine (TFMPP). Despite their popularity, there is a paucity of knowledge about their central effects in humans. This study investigated their effects on human neural processing using electroencephalographic techniques.
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Acute effects of BZP, TFMPP and the combination of BZP and TFMPP in comparison to dexamphetamine on an auditory oddball task using electroencephalography: a single-dose study
Psychopharmacology, 2016Co-Authors: Grace Y. Wang, Louise E Curley, Ian J Kirk, John J. Sollers, Robert R Kydd, Bruce R RussellAbstract:Rationale Piperazine-based designer drugs such as benzylpiperazine (BZP) and Trifluoromethylphenylpiperazine (TFMPP) have been marketed and sold as legal alternatives to dexamphetamine and 3,4-methylenedioxymethamphetamine (MDMA) until 2008 in New Zealand. When administered in combination, BZP + TFMPP have been reported to produce drug-drug synergism in rodents by stimulating the release of dopamine and serotonin. Objectives This study was to evaluate the acute event-related potential effects of BZP, TFMPP or the combination of BZP + TFMPP compared with dexamphetamine in young healthy male adults. Methods A double-blind, randomised, placebo-controlled study investigated the effects of BZP, TFMPP, the combination of BZP + TFMPP, and dexamphetamine on the event-related potentials during an auditory oddball task. Healthy, right-handed males were given a single oral dose of either BZP (200 mg), TFMPP (60 mg), a combination of BZP + TFMPP (100/30 mg), dexamphetamine (20 mg) or placebo (lactose) and tested both before and 120 min after drug administration. Results A single dose of either TMFPP ( t = −2.29, p = 0.03) or dexamphetamine ( t = −2.33, p = 0.02) significantly reduced the P300 amplitude. A similar trend was also found in BZP. In contrast, BZP and TFMPP in combination has no effect. Neither P300 latency nor the mean reaction time was affected by any of the drug treatments. In addition, neither the P100 nor the P200 component was significantly affected following any of the drug treatments. Conclusions A single oral dose of BZP or TFMPP, but not the combination of BZP/TFMPP, affected auditory sensory-evoked P300 potential in a manner similar to dexamphetamine.
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acute effects of bzp tfmpp and the combination of bzp and tfmpp in comparison to dexamphetamine on an auditory oddball task using electroencephalography a single dose study
Psychopharmacology, 2016Co-Authors: Grace Y. Wang, Louise E Curley, Ian J Kirk, John J. Sollers, Robert R Kydd, Bruce R RussellAbstract:Rationale Piperazine-based designer drugs such as benzylpiperazine (BZP) and Trifluoromethylphenylpiperazine (TFMPP) have been marketed and sold as legal alternatives to dexamphetamine and 3,4-methylenedioxymethamphetamine (MDMA) until 2008 in New Zealand. When administered in combination, BZP + TFMPP have been reported to produce drug-drug synergism in rodents by stimulating the release of dopamine and serotonin.
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Acute effects of the designer drugs benzylpiperazine (BZP) and Trifluoromethylphenylpiperazine (TFMPP) using functional magnetic resonance imaging (fMRI) and the Stroop task—a pilot study
Psychopharmacology, 2015Co-Authors: Louise E Curley, Ian J Kirk, Robert R Kydd, Michelle C. Robertson, Avinesh Pillai, Nicolas Mcnair, Bruce R RussellAbstract:Rationale A novel group of designer drugs containing benzylpiperazine (BZP) and/or Trifluoromethylphenylpiperazine (TFMPP) have been available worldwide for more than a decade; however, their effects on human brain function have not been extensively described. Objectives In a double-blind, placebo-controlled crossover study, the acute effects of BZP and TFMPP (alone and in combination) on the neural networks involved in executive function were investigated using an event-related Stroop functional magnetic resonance imaging (fMRI) paradigm. Methods Thirteen healthy participants aged 18–40 years undertook the Stroop task 90 min after taking an oral dose of either BZP (200 mg), TFMPP (either 50 or 60 mg), BZP + TFMPP (100 + 30 mg) or placebo. A change in activity in neural regions reflects an increase in local demand for oxygen, due to an increase in neuronal activity. Results Relative to placebo, an increase in neural activation was observed in the dorsal striatum following BZP, and in the thalamus following TFMPP, when performing the Stroop task. Conclusion These data suggest that additional compensatory resources were recruited to maintain performance during the Stroop task. When BZP and TFMPP were administered together, both the dorsal striatum and thalamus were activated. However, the combination of BZP/TFMPP attenuated activation in the caudate, possibly due to TFMPP’s indirect effects on dopamine release via 5HT_2C receptors.
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Acute effects of the designer drugs benzylpiperazine (BZP) and Trifluoromethylphenylpiperazine (TFMPP) using functional magnetic resonance imaging (fMRI) and the Stroop task--a pilot study.
Psychopharmacology, 2015Co-Authors: Louise E Curley, Ian J Kirk, Robert R Kydd, Michelle C. Robertson, Avinesh Pillai, Nicolas A. Mcnair, Heeseung Lee, Bruce R RussellAbstract:Rationale A novel group of designer drugs containing benzylpiperazine (BZP) and/or Trifluoromethylphenylpiperazine (TFMPP) have been available worldwide for more than a decade; however, their effects on human brain function have not been extensively described.
Ian J Kirk - One of the best experts on this subject based on the ideXlab platform.
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investigation of the effects of piperazine containing party pills and dexamphetamine on interhemispheric communication using electroencephalography
Psychopharmacology, 2016Co-Authors: Grace Y. Wang, Louise E Curley, Ian J Kirk, Robert R Kydd, Bruce R RussellAbstract:Background ‘Piperazine-containing party pills’ were marketed and sold as legal alternatives to methamphetamine and 3,4-methylenedioxymethamphetamine (MDMA) until 2008 in New Zealand. The major constituents of these ‘pills’ were benzylphenylpiperazine (BZP) and Trifluoromethylphenylpiperazine (TFMPP). Despite their popularity, there is a paucity of knowledge about their central effects in humans. This study investigated their effects on human neural processing using electroencephalographic techniques.
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Acute effects of BZP, TFMPP and the combination of BZP and TFMPP in comparison to dexamphetamine on an auditory oddball task using electroencephalography: a single-dose study
Psychopharmacology, 2016Co-Authors: Grace Y. Wang, Louise E Curley, Ian J Kirk, John J. Sollers, Robert R Kydd, Bruce R RussellAbstract:Rationale Piperazine-based designer drugs such as benzylpiperazine (BZP) and Trifluoromethylphenylpiperazine (TFMPP) have been marketed and sold as legal alternatives to dexamphetamine and 3,4-methylenedioxymethamphetamine (MDMA) until 2008 in New Zealand. When administered in combination, BZP + TFMPP have been reported to produce drug-drug synergism in rodents by stimulating the release of dopamine and serotonin. Objectives This study was to evaluate the acute event-related potential effects of BZP, TFMPP or the combination of BZP + TFMPP compared with dexamphetamine in young healthy male adults. Methods A double-blind, randomised, placebo-controlled study investigated the effects of BZP, TFMPP, the combination of BZP + TFMPP, and dexamphetamine on the event-related potentials during an auditory oddball task. Healthy, right-handed males were given a single oral dose of either BZP (200 mg), TFMPP (60 mg), a combination of BZP + TFMPP (100/30 mg), dexamphetamine (20 mg) or placebo (lactose) and tested both before and 120 min after drug administration. Results A single dose of either TMFPP ( t = −2.29, p = 0.03) or dexamphetamine ( t = −2.33, p = 0.02) significantly reduced the P300 amplitude. A similar trend was also found in BZP. In contrast, BZP and TFMPP in combination has no effect. Neither P300 latency nor the mean reaction time was affected by any of the drug treatments. In addition, neither the P100 nor the P200 component was significantly affected following any of the drug treatments. Conclusions A single oral dose of BZP or TFMPP, but not the combination of BZP/TFMPP, affected auditory sensory-evoked P300 potential in a manner similar to dexamphetamine.
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acute effects of bzp tfmpp and the combination of bzp and tfmpp in comparison to dexamphetamine on an auditory oddball task using electroencephalography a single dose study
Psychopharmacology, 2016Co-Authors: Grace Y. Wang, Louise E Curley, Ian J Kirk, John J. Sollers, Robert R Kydd, Bruce R RussellAbstract:Rationale Piperazine-based designer drugs such as benzylpiperazine (BZP) and Trifluoromethylphenylpiperazine (TFMPP) have been marketed and sold as legal alternatives to dexamphetamine and 3,4-methylenedioxymethamphetamine (MDMA) until 2008 in New Zealand. When administered in combination, BZP + TFMPP have been reported to produce drug-drug synergism in rodents by stimulating the release of dopamine and serotonin.
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Acute effects of the designer drugs benzylpiperazine (BZP) and Trifluoromethylphenylpiperazine (TFMPP) using functional magnetic resonance imaging (fMRI) and the Stroop task—a pilot study
Psychopharmacology, 2015Co-Authors: Louise E Curley, Ian J Kirk, Robert R Kydd, Michelle C. Robertson, Avinesh Pillai, Nicolas Mcnair, Bruce R RussellAbstract:Rationale A novel group of designer drugs containing benzylpiperazine (BZP) and/or Trifluoromethylphenylpiperazine (TFMPP) have been available worldwide for more than a decade; however, their effects on human brain function have not been extensively described. Objectives In a double-blind, placebo-controlled crossover study, the acute effects of BZP and TFMPP (alone and in combination) on the neural networks involved in executive function were investigated using an event-related Stroop functional magnetic resonance imaging (fMRI) paradigm. Methods Thirteen healthy participants aged 18–40 years undertook the Stroop task 90 min after taking an oral dose of either BZP (200 mg), TFMPP (either 50 or 60 mg), BZP + TFMPP (100 + 30 mg) or placebo. A change in activity in neural regions reflects an increase in local demand for oxygen, due to an increase in neuronal activity. Results Relative to placebo, an increase in neural activation was observed in the dorsal striatum following BZP, and in the thalamus following TFMPP, when performing the Stroop task. Conclusion These data suggest that additional compensatory resources were recruited to maintain performance during the Stroop task. When BZP and TFMPP were administered together, both the dorsal striatum and thalamus were activated. However, the combination of BZP/TFMPP attenuated activation in the caudate, possibly due to TFMPP’s indirect effects on dopamine release via 5HT_2C receptors.
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Acute effects of the designer drugs benzylpiperazine (BZP) and Trifluoromethylphenylpiperazine (TFMPP) using functional magnetic resonance imaging (fMRI) and the Stroop task--a pilot study.
Psychopharmacology, 2015Co-Authors: Louise E Curley, Ian J Kirk, Robert R Kydd, Michelle C. Robertson, Avinesh Pillai, Nicolas A. Mcnair, Heeseung Lee, Bruce R RussellAbstract:Rationale A novel group of designer drugs containing benzylpiperazine (BZP) and/or Trifluoromethylphenylpiperazine (TFMPP) have been available worldwide for more than a decade; however, their effects on human brain function have not been extensively described.
Louise E Curley - One of the best experts on this subject based on the ideXlab platform.
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investigation of the effects of piperazine containing party pills and dexamphetamine on interhemispheric communication using electroencephalography
Psychopharmacology, 2016Co-Authors: Grace Y. Wang, Louise E Curley, Ian J Kirk, Robert R Kydd, Bruce R RussellAbstract:Background ‘Piperazine-containing party pills’ were marketed and sold as legal alternatives to methamphetamine and 3,4-methylenedioxymethamphetamine (MDMA) until 2008 in New Zealand. The major constituents of these ‘pills’ were benzylphenylpiperazine (BZP) and Trifluoromethylphenylpiperazine (TFMPP). Despite their popularity, there is a paucity of knowledge about their central effects in humans. This study investigated their effects on human neural processing using electroencephalographic techniques.
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Acute effects of BZP, TFMPP and the combination of BZP and TFMPP in comparison to dexamphetamine on an auditory oddball task using electroencephalography: a single-dose study
Psychopharmacology, 2016Co-Authors: Grace Y. Wang, Louise E Curley, Ian J Kirk, John J. Sollers, Robert R Kydd, Bruce R RussellAbstract:Rationale Piperazine-based designer drugs such as benzylpiperazine (BZP) and Trifluoromethylphenylpiperazine (TFMPP) have been marketed and sold as legal alternatives to dexamphetamine and 3,4-methylenedioxymethamphetamine (MDMA) until 2008 in New Zealand. When administered in combination, BZP + TFMPP have been reported to produce drug-drug synergism in rodents by stimulating the release of dopamine and serotonin. Objectives This study was to evaluate the acute event-related potential effects of BZP, TFMPP or the combination of BZP + TFMPP compared with dexamphetamine in young healthy male adults. Methods A double-blind, randomised, placebo-controlled study investigated the effects of BZP, TFMPP, the combination of BZP + TFMPP, and dexamphetamine on the event-related potentials during an auditory oddball task. Healthy, right-handed males were given a single oral dose of either BZP (200 mg), TFMPP (60 mg), a combination of BZP + TFMPP (100/30 mg), dexamphetamine (20 mg) or placebo (lactose) and tested both before and 120 min after drug administration. Results A single dose of either TMFPP ( t = −2.29, p = 0.03) or dexamphetamine ( t = −2.33, p = 0.02) significantly reduced the P300 amplitude. A similar trend was also found in BZP. In contrast, BZP and TFMPP in combination has no effect. Neither P300 latency nor the mean reaction time was affected by any of the drug treatments. In addition, neither the P100 nor the P200 component was significantly affected following any of the drug treatments. Conclusions A single oral dose of BZP or TFMPP, but not the combination of BZP/TFMPP, affected auditory sensory-evoked P300 potential in a manner similar to dexamphetamine.
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acute effects of bzp tfmpp and the combination of bzp and tfmpp in comparison to dexamphetamine on an auditory oddball task using electroencephalography a single dose study
Psychopharmacology, 2016Co-Authors: Grace Y. Wang, Louise E Curley, Ian J Kirk, John J. Sollers, Robert R Kydd, Bruce R RussellAbstract:Rationale Piperazine-based designer drugs such as benzylpiperazine (BZP) and Trifluoromethylphenylpiperazine (TFMPP) have been marketed and sold as legal alternatives to dexamphetamine and 3,4-methylenedioxymethamphetamine (MDMA) until 2008 in New Zealand. When administered in combination, BZP + TFMPP have been reported to produce drug-drug synergism in rodents by stimulating the release of dopamine and serotonin.
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Acute effects of the designer drugs benzylpiperazine (BZP) and Trifluoromethylphenylpiperazine (TFMPP) using functional magnetic resonance imaging (fMRI) and the Stroop task—a pilot study
Psychopharmacology, 2015Co-Authors: Louise E Curley, Ian J Kirk, Robert R Kydd, Michelle C. Robertson, Avinesh Pillai, Nicolas Mcnair, Bruce R RussellAbstract:Rationale A novel group of designer drugs containing benzylpiperazine (BZP) and/or Trifluoromethylphenylpiperazine (TFMPP) have been available worldwide for more than a decade; however, their effects on human brain function have not been extensively described. Objectives In a double-blind, placebo-controlled crossover study, the acute effects of BZP and TFMPP (alone and in combination) on the neural networks involved in executive function were investigated using an event-related Stroop functional magnetic resonance imaging (fMRI) paradigm. Methods Thirteen healthy participants aged 18–40 years undertook the Stroop task 90 min after taking an oral dose of either BZP (200 mg), TFMPP (either 50 or 60 mg), BZP + TFMPP (100 + 30 mg) or placebo. A change in activity in neural regions reflects an increase in local demand for oxygen, due to an increase in neuronal activity. Results Relative to placebo, an increase in neural activation was observed in the dorsal striatum following BZP, and in the thalamus following TFMPP, when performing the Stroop task. Conclusion These data suggest that additional compensatory resources were recruited to maintain performance during the Stroop task. When BZP and TFMPP were administered together, both the dorsal striatum and thalamus were activated. However, the combination of BZP/TFMPP attenuated activation in the caudate, possibly due to TFMPP’s indirect effects on dopamine release via 5HT_2C receptors.
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Acute effects of the designer drugs benzylpiperazine (BZP) and Trifluoromethylphenylpiperazine (TFMPP) using functional magnetic resonance imaging (fMRI) and the Stroop task--a pilot study.
Psychopharmacology, 2015Co-Authors: Louise E Curley, Ian J Kirk, Robert R Kydd, Michelle C. Robertson, Avinesh Pillai, Nicolas A. Mcnair, Heeseung Lee, Bruce R RussellAbstract:Rationale A novel group of designer drugs containing benzylpiperazine (BZP) and/or Trifluoromethylphenylpiperazine (TFMPP) have been available worldwide for more than a decade; however, their effects on human brain function have not been extensively described.
Melissa Girling - One of the best experts on this subject based on the ideXlab platform.
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Patterns of benzylpiperazine/Trifluoromethylphenylpiperazine party pill use and adverse effects in a population sample in New Zealand
Drug and Alcohol Review, 2008Co-Authors: Chris Wilkins, Paul Sweetsur, Melissa GirlingAbstract:Introduction and Aims. A large legal market for party pills containing benzylpiperazine (BZP) and Trifluoromethylphenylpiperazine (TFMPP) developed in New Zealand after 2004. The use of these party pills has been associated with adverse health effects. The purpose of this paper was to assess a general population sample of party pill users to investigate the relationship between (1) patterns of use of BZP/TFMPP party pills and concurrent use of other drug types, and (2) adverse side effects from BZP/TFMPP party pill use. Design. A national household survey of the use of BZP/TFMPP party pills was conducted using a computer-assisted telephone interviewing (CATI) facility. The quantity of BZP and TFMPP in each brand of party pill was obtained from the National Poisons Centre. Multiple logistic regression analysis was used to identify independent predictors of having experienced adverse side effects from party pills. Results. The mean quantity of BZP/TFMPP taken on an occasion of greatest use was 533 mg (media...
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patterns of benzylpiperazine Trifluoromethylphenylpiperazine party pill use and adverse effects in a population sample in new zealand
Drug and Alcohol Review, 2008Co-Authors: Chris Wilkins, Paul Sweetsur, Melissa GirlingAbstract:Introduction and Aims. A large legal market for party pills containing benzylpiperazine (BZP) and Trifluoromethylphenylpiperazine (TFMPP) developed in New Zealand after 2004. The use of these party pills has been associated with adverse health effects. The purpose of this paper was to assess a general population sample of party pill users to investigate the relationship between (1) patterns of use of BZP/TFMPP party pills and concurrent use of other drug types, and (2) adverse side effects from BZP/TFMPP party pill use. Design. A national household survey of the use of BZP/TFMPP party pills was conducted using a computer-assisted telephone interviewing (CATI) facility. The quantity of BZP and TFMPP in each brand of party pill was obtained from the National Poisons Centre. Multiple logistic regression analysis was used to identify independent predictors of having experienced adverse side effects from party pills. Results. The mean quantity of BZP/TFMPP taken on an occasion of greatest use was 533 mg (media...
