Tuberculous Cervical Lymphadenitis

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Gustavo Reyesteran - One of the best experts on this subject based on the ideXlab platform.

  • xpert mtb rif for diagnosis of Tuberculous Cervical Lymphadenitis in hiv infected patients
    Laryngoscope, 2014
    Co-Authors: Yuria Ablanedoterrazas, Claudia Alvaradode La Barrera, Ramon Hernandezjuan, Matilde Ruizcruz, Gustavo Reyesteran
    Abstract:

    Objectives/Hypothesis The World Health Organization endorsed the Xpert MTB/RIF assay for the diagnosis of pulmonary tuberculosis (TB), but there is limited information about the utility of this assay for the diagnosis of TB Lymphadenitis. Therefore, the objective of this study was to assess the diagnostic accuracy of Xpert MTB/RIF assay in HIV-infected patients with palpable Cervical lymph nodes. Study Design Prospective, diagnostic test study. Methods Consecutive patients with Cervical lymphadenopathy were prospectively enrolled between January 2011 and March 2013. Lymph node specimens were obtained through fine-needle aspiration or excisional biopsy. Mycobacterial culture was considered as the gold standard. Results Mycobacterium TB was cultured from 15 of 68 specimens (22.05%), and 53 specimens had negative cultures (77.94%). The sensitivity of Xpert MTB/RIF was 100% (95% CI, 74.65%–100%), and the specificity was 100% (95% CI, 91.58%–100%). Smear microscopy had a lower diagnostic performance. Conclusion Although based on a limited sample size, our study indicates that Xpert MTB/RIF is a useful method for the diagnosis of Cervical TB Lymphadenitis in HIV-infected patients, regardless of the bacillary load in smear-positive samples or the CD4 T cell count. The sensitivity, specificity, positive predictive value, and negative predictive value were similar to gold-standard culture. Level of Evidence N/A. Laryngoscope, 124:1382–1385, 2014

Wonjin Moon - One of the best experts on this subject based on the ideXlab platform.

Yuria Ablanedoterrazas - One of the best experts on this subject based on the ideXlab platform.

  • xpert mtb rif for diagnosis of Tuberculous Cervical Lymphadenitis in hiv infected patients
    Laryngoscope, 2014
    Co-Authors: Yuria Ablanedoterrazas, Claudia Alvaradode La Barrera, Ramon Hernandezjuan, Matilde Ruizcruz, Gustavo Reyesteran
    Abstract:

    Objectives/Hypothesis The World Health Organization endorsed the Xpert MTB/RIF assay for the diagnosis of pulmonary tuberculosis (TB), but there is limited information about the utility of this assay for the diagnosis of TB Lymphadenitis. Therefore, the objective of this study was to assess the diagnostic accuracy of Xpert MTB/RIF assay in HIV-infected patients with palpable Cervical lymph nodes. Study Design Prospective, diagnostic test study. Methods Consecutive patients with Cervical lymphadenopathy were prospectively enrolled between January 2011 and March 2013. Lymph node specimens were obtained through fine-needle aspiration or excisional biopsy. Mycobacterial culture was considered as the gold standard. Results Mycobacterium TB was cultured from 15 of 68 specimens (22.05%), and 53 specimens had negative cultures (77.94%). The sensitivity of Xpert MTB/RIF was 100% (95% CI, 74.65%–100%), and the specificity was 100% (95% CI, 91.58%–100%). Smear microscopy had a lower diagnostic performance. Conclusion Although based on a limited sample size, our study indicates that Xpert MTB/RIF is a useful method for the diagnosis of Cervical TB Lymphadenitis in HIV-infected patients, regardless of the bacillary load in smear-positive samples or the CD4 T cell count. The sensitivity, specificity, positive predictive value, and negative predictive value were similar to gold-standard culture. Level of Evidence N/A. Laryngoscope, 124:1382–1385, 2014

Eun Chang Choi - One of the best experts on this subject based on the ideXlab platform.

Claudia Alvaradode La Barrera - One of the best experts on this subject based on the ideXlab platform.

  • xpert mtb rif for diagnosis of Tuberculous Cervical Lymphadenitis in hiv infected patients
    Laryngoscope, 2014
    Co-Authors: Yuria Ablanedoterrazas, Claudia Alvaradode La Barrera, Ramon Hernandezjuan, Matilde Ruizcruz, Gustavo Reyesteran
    Abstract:

    Objectives/Hypothesis The World Health Organization endorsed the Xpert MTB/RIF assay for the diagnosis of pulmonary tuberculosis (TB), but there is limited information about the utility of this assay for the diagnosis of TB Lymphadenitis. Therefore, the objective of this study was to assess the diagnostic accuracy of Xpert MTB/RIF assay in HIV-infected patients with palpable Cervical lymph nodes. Study Design Prospective, diagnostic test study. Methods Consecutive patients with Cervical lymphadenopathy were prospectively enrolled between January 2011 and March 2013. Lymph node specimens were obtained through fine-needle aspiration or excisional biopsy. Mycobacterial culture was considered as the gold standard. Results Mycobacterium TB was cultured from 15 of 68 specimens (22.05%), and 53 specimens had negative cultures (77.94%). The sensitivity of Xpert MTB/RIF was 100% (95% CI, 74.65%–100%), and the specificity was 100% (95% CI, 91.58%–100%). Smear microscopy had a lower diagnostic performance. Conclusion Although based on a limited sample size, our study indicates that Xpert MTB/RIF is a useful method for the diagnosis of Cervical TB Lymphadenitis in HIV-infected patients, regardless of the bacillary load in smear-positive samples or the CD4 T cell count. The sensitivity, specificity, positive predictive value, and negative predictive value were similar to gold-standard culture. Level of Evidence N/A. Laryngoscope, 124:1382–1385, 2014

  • Xpert MTB/RIF for diagnosis of Tuberculous Cervical Lymphadenitis in HIV‐infected patients
    Laryngoscope, 2013
    Co-Authors: Yuria Ablanedo-terrazas, Claudia Alvaradode La Barrera, Ramón Hernández-juan, Matilde Ruiz-cruz, Gustavo Reyes-terán
    Abstract:

    Objectives/Hypothesis The World Health Organization endorsed the Xpert MTB/RIF assay for the diagnosis of pulmonary tuberculosis (TB), but there is limited information about the utility of this assay for the diagnosis of TB Lymphadenitis. Therefore, the objective of this study was to assess the diagnostic accuracy of Xpert MTB/RIF assay in HIV-infected patients with palpable Cervical lymph nodes. Study Design Prospective, diagnostic test study. Methods Consecutive patients with Cervical lymphadenopathy were prospectively enrolled between January 2011 and March 2013. Lymph node specimens were obtained through fine-needle aspiration or excisional biopsy. Mycobacterial culture was considered as the gold standard. Results Mycobacterium TB was cultured from 15 of 68 specimens (22.05%), and 53 specimens had negative cultures (77.94%). The sensitivity of Xpert MTB/RIF was 100% (95% CI, 74.65%–100%), and the specificity was 100% (95% CI, 91.58%–100%). Smear microscopy had a lower diagnostic performance. Conclusion Although based on a limited sample size, our study indicates that Xpert MTB/RIF is a useful method for the diagnosis of Cervical TB Lymphadenitis in HIV-infected patients, regardless of the bacillary load in smear-positive samples or the CD4 T cell count. The sensitivity, specificity, positive predictive value, and negative predictive value were similar to gold-standard culture. Level of Evidence N/A. Laryngoscope, 124:1382–1385, 2014