The Experts below are selected from a list of 30 Experts worldwide ranked by ideXlab platform
Saroj Kumar Rath - One of the best experts on this subject based on the ideXlab platform.
-
A TYPICAL MEDIAN RHOMBOID GLOSSITIS: A CASE REPORT
Indian Journal of Case Reports, 2018Co-Authors: Priyanka Nath, Saroj Kumar RathAbstract:Median rhomboid glossitis or glossal central papillary atrophy is characterized by an area of redness and loss of filiform papillae, situated on the dorsum of the tongue in front of the circumvallate papillae. Smoking, denture wearing, use of corticosteroid sprays or inhalers, and human immunodeficiency virus are few of the predisposing factors. Previously, this condition was believed to be a developmental defect of the tongue, caused by a failure of the Tuberculum impar to be covered by the lateral processes of the tongue; however, now, it is thought to be due to chronic candidiasis. This paper presents an atypical case of rhomboid glossitis in a 4-year-old girl, discussing the clinical presentation, etiological factors, and differential diagnosis.
Priyanka Nath - One of the best experts on this subject based on the ideXlab platform.
-
A TYPICAL MEDIAN RHOMBOID GLOSSITIS: A CASE REPORT
Indian Journal of Case Reports, 2018Co-Authors: Priyanka Nath, Saroj Kumar RathAbstract:Median rhomboid glossitis or glossal central papillary atrophy is characterized by an area of redness and loss of filiform papillae, situated on the dorsum of the tongue in front of the circumvallate papillae. Smoking, denture wearing, use of corticosteroid sprays or inhalers, and human immunodeficiency virus are few of the predisposing factors. Previously, this condition was believed to be a developmental defect of the tongue, caused by a failure of the Tuberculum impar to be covered by the lateral processes of the tongue; however, now, it is thought to be due to chronic candidiasis. This paper presents an atypical case of rhomboid glossitis in a 4-year-old girl, discussing the clinical presentation, etiological factors, and differential diagnosis.
Harold C. Slavkin - One of the best experts on this subject based on the ideXlab platform.
-
Desmin expression during early mouse tongue morphogenesis
The International journal of developmental biology, 1992Co-Authors: Mark Mayo, Pablo Bringas, Valentino Santos, Lillian Shum, Harold C. SlavkinAbstract:Occipital somites provide progenitor cells for craniofacial muscle development including the tongue musculature. Serum-derived factors are assumed to be pre-requisite for myogenesis in vitro. To test these assertions, we designed experiments to determine whether early mouse tongue development in general, and desmin localization in particular, were expressed during the development of embryonic mouse first branchial arch explants cultured in serumless, chemically-defined medium. Immunohistochemical techniques determined the chronology and positions of desmin expression during early craniofacial development. Occipital somites expressed desmin at E9 (9 days +/- 2 h post-fertilization, 18-20 somites). A discrete cell migration pathway initiating in the somites and terminating in the lateral lingual processes of the tongue primordium was defined based upon desmin expression patterns in E9-E11 embryos and computer-assisted three dimensional reconstructions. The in vitro model system was permissive for tongue morphogenesis, allowing development and fusion of the lateral lingual processes with the Tuberculum impar. During culture myoblasts were not observed to fuse into myotubes with sarcomeric assembly, even though explant myoblasts produced muscle-specific protein. E10 explants cultured for 9 days demonstrated a five-fold increase in cell number that expressed desmin (P less than 0.05) when compared to the E10 starting material. We interpret these results to indicate that the tongue myogenic cell lineage was determined between E8 and E11, and that this resident population expanded within explants cultured in serumless medium by several explanations: (i) cells other than progenitor myoblasts (e.g., satellite cells) were induced to become myoblasts, and/or (ii) progenitor myoblasts within the original explants expanded by cell division in the absence of serum factors.(ABSTRACT TRUNCATED AT 250 WORDS)
Mahmoud Sakr - One of the best experts on this subject based on the ideXlab platform.
-
Surgery of the Thyroid Glands
Head and Neck and Endocrine Surgery, 2016Co-Authors: Mahmoud SakrAbstract:In the fetus, at 3–4 weeks of gestation, the thyroid gland appears as an epithelial proliferation in the floor of the pharynx at the base of the tongue between the Tuberculum impar and the copula linguae, at a point later indicated by the foramen cecum. The thyroid then descends in front of the pharyngeal gut as a bilobed diverticulum through the thyroglossal duct. Over the next few weeks, it migrates to the base of the neck. During migration, the thyroid remains connected to the tongue by a narrow canal, the thyroglossal duct.
Mark Mayo - One of the best experts on this subject based on the ideXlab platform.
-
Desmin expression during early mouse tongue morphogenesis
The International journal of developmental biology, 1992Co-Authors: Mark Mayo, Pablo Bringas, Valentino Santos, Lillian Shum, Harold C. SlavkinAbstract:Occipital somites provide progenitor cells for craniofacial muscle development including the tongue musculature. Serum-derived factors are assumed to be pre-requisite for myogenesis in vitro. To test these assertions, we designed experiments to determine whether early mouse tongue development in general, and desmin localization in particular, were expressed during the development of embryonic mouse first branchial arch explants cultured in serumless, chemically-defined medium. Immunohistochemical techniques determined the chronology and positions of desmin expression during early craniofacial development. Occipital somites expressed desmin at E9 (9 days +/- 2 h post-fertilization, 18-20 somites). A discrete cell migration pathway initiating in the somites and terminating in the lateral lingual processes of the tongue primordium was defined based upon desmin expression patterns in E9-E11 embryos and computer-assisted three dimensional reconstructions. The in vitro model system was permissive for tongue morphogenesis, allowing development and fusion of the lateral lingual processes with the Tuberculum impar. During culture myoblasts were not observed to fuse into myotubes with sarcomeric assembly, even though explant myoblasts produced muscle-specific protein. E10 explants cultured for 9 days demonstrated a five-fold increase in cell number that expressed desmin (P less than 0.05) when compared to the E10 starting material. We interpret these results to indicate that the tongue myogenic cell lineage was determined between E8 and E11, and that this resident population expanded within explants cultured in serumless medium by several explanations: (i) cells other than progenitor myoblasts (e.g., satellite cells) were induced to become myoblasts, and/or (ii) progenitor myoblasts within the original explants expanded by cell division in the absence of serum factors.(ABSTRACT TRUNCATED AT 250 WORDS)
