The Experts below are selected from a list of 303 Experts worldwide ranked by ideXlab platform
Sverker Hansson - One of the best experts on this subject based on the ideXlab platform.
-
the swedish reflux trial in children iii Urinary Tract Infection pattern
The Journal of Urology, 2010Co-Authors: Per Brandstrom, Svante Swerkersson, U Jodal, Elisabeth Esbjorner, Maria Herthelius, Sverker HanssonAbstract:Purpose: We evaluated the difference in the febrile Urinary Tract Infection rate in small children with dilating vesicoureteral reflux randomly allocated to 3 management alternatives, including antibiotic prophylaxis, endoscopic treatment or surveillance only as the control.Materials and Methods: At 23 centers a total of 203 children were included in the study, including 128 girls and 75 boys 1 to younger than 2 years. Vesicoureteral reflux grade III in 126 cases and IV in 77 was detected after a febrile Urinary Tract Infection (194) after prenatal screening (9). Voiding cystourethrography and dimercapto-succinic acid scintigraphy were done before randomization and after 2 years. The febrile Urinary Tract Infection rate was analyzed by the intent to treat principle.Results: We noted a total of 67 febrile recurrences in 42 girls and a total of 8 in 7 boys (p = 0.0001). There was a difference in the recurrence rate among treatment groups in girls with febrile Infection in 8 of 43 (19%) on prophylaxis, 10 of...
-
relationship among vesicoureteral reflux Urinary Tract Infection and renal damage in children
The Journal of Urology, 2007Co-Authors: Svante Swerkersson, U Jodal, Rune Sixt, Eira Stokland, Sverker HanssonAbstract:Purpose: We studied the relationship among vesicoureteral reflux, Urinary Tract Infection and permanent renal damage in children.Materials and Methods: We retrospectively analyzed 303 children younger than 2 years with a first time, nonobstructive, culture verified Urinary Tract Infection. The protocol included ultrasonography and voiding cystourethrography within 3 months after Urinary Tract Infection, and 99mtechnetium dimercapto-succinic acid scintigraphy after 1 to 2 years.Results: Vesicoureteral reflux was found in 36 of 163 boys (22%) and in 44 of 140 girls (31%). Of the 303 patients 80 (26%) had permanent renal damage according to dimercapto-succinic acid scintigraphy. The rate of abnormality increased significantly with grade of vesicoureteral reflux in boys and girls. The relative risk of renal damage was significantly increased in patients with vesicoureteral reflux grade II and higher. Maximum C-reactive protein concentration, maximum temperature during Urinary Tract Infection, presence of vesi...
Rune Sixt - One of the best experts on this subject based on the ideXlab platform.
-
relationship among vesicoureteral reflux Urinary Tract Infection and renal damage in children
The Journal of Urology, 2007Co-Authors: Svante Swerkersson, U Jodal, Rune Sixt, Eira Stokland, Sverker HanssonAbstract:Purpose: We studied the relationship among vesicoureteral reflux, Urinary Tract Infection and permanent renal damage in children.Materials and Methods: We retrospectively analyzed 303 children younger than 2 years with a first time, nonobstructive, culture verified Urinary Tract Infection. The protocol included ultrasonography and voiding cystourethrography within 3 months after Urinary Tract Infection, and 99mtechnetium dimercapto-succinic acid scintigraphy after 1 to 2 years.Results: Vesicoureteral reflux was found in 36 of 163 boys (22%) and in 44 of 140 girls (31%). Of the 303 patients 80 (26%) had permanent renal damage according to dimercapto-succinic acid scintigraphy. The rate of abnormality increased significantly with grade of vesicoureteral reflux in boys and girls. The relative risk of renal damage was significantly increased in patients with vesicoureteral reflux grade II and higher. Maximum C-reactive protein concentration, maximum temperature during Urinary Tract Infection, presence of vesi...
-
renal damage one year after first Urinary Tract Infection role of dimercaptosuccinic acid scintigraphy
The Journal of Pediatrics, 1996Co-Authors: Eira Stokland, U Jodal, Mikael Hellstrom, Bo Jacobsson, Rune SixtAbstract:AbsTract OBJECTIVE: The aim of this study was to determine whether age, C-reactive protein (CRP), body temperature, or results of voiding cystourethrography at diagnosis of first-time symptomatic Urinary Tract Infection could predict the risk of renal damage as evaluated by dimercaptosuccinic acid (DMSA) scintigraphy performed 1 year after the Infection. DESIGN: The study included 157 children (median age, 0.4 year, range, 5 days to 5.8 years) with first-time symptomatic Urinary Tract Infection. In children 1 year of age or older, a body temperature of 38.5° C or higher was necessary for inclusion. CRP and body temperature were measured at the time of Infection, and voiding cystourethrography was performed shortly thereafter. DMSA scintigraphy was performed 1 year later in all children. RESULTS: After 1 year, 59 (38%) of the 157 children had renal damage as evaluated by DMSA scintigraphy, and of these, 28 (47%) had reflux. There was a positive correlation between renal damage and CRP, body temperature, and reflux. Children with high levels of CRP, high fever, and dilating reflux had a risk of renal damage up to 10 times higher than children with normal or slightly elevated CRP levels, no or mild fever, and no reflux. CONCLUSION: CRP concentration and body temperature at the index Infection, in combination with the results of voiding cystourethrography, are useful in classifying children at high and low risk of scintigraphic renal damage 1 year after Urinary Tract Infection. (J Pediatr 1996;129:815-20)
-
early 99mtc dimercaptosuccinic acid dmsa scintigraphy in symptomatic first time Urinary Tract Infection
Acta Paediatrica, 1996Co-Authors: Eira Stokland, U Jodal, Mikael Hellstrom, Bo Jacobsson, Pia Lundgren, Rune SixtAbstract:During a 2 year period, 175 children below 6 years of age (median 0.4 year) with non-obstructive symptomatic Urinary Tract Infection were studied by 99m Tc dimercaptosuccinic acid (DMSA) scintigraphy. DMSA scintigraphy was performed at a median of 10 days after the start of treatment and was abnormal in 73 children (42%), equivocal in 29 (16%) and normal in 73 (42% Reflux was seen in 27% of all children and in 38% of the renal units that were abnormal at DMSA scintigraphy. A decreasing frequency of abnormalities at DMSA scintigraphy was seen within the first 14 days after the start of treatment. C-reactive protein and grade of reflux correlated significantly with abnormal DMSA studies. To demonstrate renal involvement in acute Urinary Tract Infection, DMSA scintigraphy should be performed within days after the start of treatment. It is noteworthy that reflux was seen in less than half of renal units with abnormal DMSA scintigraphy.
U Jodal - One of the best experts on this subject based on the ideXlab platform.
-
the swedish reflux trial in children iii Urinary Tract Infection pattern
The Journal of Urology, 2010Co-Authors: Per Brandstrom, Svante Swerkersson, U Jodal, Elisabeth Esbjorner, Maria Herthelius, Sverker HanssonAbstract:Purpose: We evaluated the difference in the febrile Urinary Tract Infection rate in small children with dilating vesicoureteral reflux randomly allocated to 3 management alternatives, including antibiotic prophylaxis, endoscopic treatment or surveillance only as the control.Materials and Methods: At 23 centers a total of 203 children were included in the study, including 128 girls and 75 boys 1 to younger than 2 years. Vesicoureteral reflux grade III in 126 cases and IV in 77 was detected after a febrile Urinary Tract Infection (194) after prenatal screening (9). Voiding cystourethrography and dimercapto-succinic acid scintigraphy were done before randomization and after 2 years. The febrile Urinary Tract Infection rate was analyzed by the intent to treat principle.Results: We noted a total of 67 febrile recurrences in 42 girls and a total of 8 in 7 boys (p = 0.0001). There was a difference in the recurrence rate among treatment groups in girls with febrile Infection in 8 of 43 (19%) on prophylaxis, 10 of...
-
relationship among vesicoureteral reflux Urinary Tract Infection and renal damage in children
The Journal of Urology, 2007Co-Authors: Svante Swerkersson, U Jodal, Rune Sixt, Eira Stokland, Sverker HanssonAbstract:Purpose: We studied the relationship among vesicoureteral reflux, Urinary Tract Infection and permanent renal damage in children.Materials and Methods: We retrospectively analyzed 303 children younger than 2 years with a first time, nonobstructive, culture verified Urinary Tract Infection. The protocol included ultrasonography and voiding cystourethrography within 3 months after Urinary Tract Infection, and 99mtechnetium dimercapto-succinic acid scintigraphy after 1 to 2 years.Results: Vesicoureteral reflux was found in 36 of 163 boys (22%) and in 44 of 140 girls (31%). Of the 303 patients 80 (26%) had permanent renal damage according to dimercapto-succinic acid scintigraphy. The rate of abnormality increased significantly with grade of vesicoureteral reflux in boys and girls. The relative risk of renal damage was significantly increased in patients with vesicoureteral reflux grade II and higher. Maximum C-reactive protein concentration, maximum temperature during Urinary Tract Infection, presence of vesi...
-
incidence rate of first time symptomatic Urinary Tract Infection in children under 6 years of age
Acta Paediatrica, 2007Co-Authors: Staffan Marild, U JodalAbstract:: A retrospective population-based study was performed to describe the incidence rate of first time symptomatic Urinary Tract Infection in children under 6 y of age. A total number of 299 children was identified during the 20-month study period in a population of 20,000 girls and 21,000 boys. The cumulative incidence rate during the first 6 y of life was 6.6% for girls and 1.8% for boys. The annual incidence rate in girls of Urinary Tract Infection/1000 at risk was between 9 and 14 for each of the six 1-y age intervals. In girls, the proportion of febrile Urinary Tract Infection was high during the infant year, while girls older than 2 y most often had non-febrile Infection. For infant boys, the incidence rate and the proportion of febrile Urinary Tract Infection were comparable to that of girls, while after the first year of life Urinary Infection of any kind was rare, with an incidence rate of 1-2/1000 at risk.
-
renal damage one year after first Urinary Tract Infection role of dimercaptosuccinic acid scintigraphy
The Journal of Pediatrics, 1996Co-Authors: Eira Stokland, U Jodal, Mikael Hellstrom, Bo Jacobsson, Rune SixtAbstract:AbsTract OBJECTIVE: The aim of this study was to determine whether age, C-reactive protein (CRP), body temperature, or results of voiding cystourethrography at diagnosis of first-time symptomatic Urinary Tract Infection could predict the risk of renal damage as evaluated by dimercaptosuccinic acid (DMSA) scintigraphy performed 1 year after the Infection. DESIGN: The study included 157 children (median age, 0.4 year, range, 5 days to 5.8 years) with first-time symptomatic Urinary Tract Infection. In children 1 year of age or older, a body temperature of 38.5° C or higher was necessary for inclusion. CRP and body temperature were measured at the time of Infection, and voiding cystourethrography was performed shortly thereafter. DMSA scintigraphy was performed 1 year later in all children. RESULTS: After 1 year, 59 (38%) of the 157 children had renal damage as evaluated by DMSA scintigraphy, and of these, 28 (47%) had reflux. There was a positive correlation between renal damage and CRP, body temperature, and reflux. Children with high levels of CRP, high fever, and dilating reflux had a risk of renal damage up to 10 times higher than children with normal or slightly elevated CRP levels, no or mild fever, and no reflux. CONCLUSION: CRP concentration and body temperature at the index Infection, in combination with the results of voiding cystourethrography, are useful in classifying children at high and low risk of scintigraphic renal damage 1 year after Urinary Tract Infection. (J Pediatr 1996;129:815-20)
-
early 99mtc dimercaptosuccinic acid dmsa scintigraphy in symptomatic first time Urinary Tract Infection
Acta Paediatrica, 1996Co-Authors: Eira Stokland, U Jodal, Mikael Hellstrom, Bo Jacobsson, Pia Lundgren, Rune SixtAbstract:During a 2 year period, 175 children below 6 years of age (median 0.4 year) with non-obstructive symptomatic Urinary Tract Infection were studied by 99m Tc dimercaptosuccinic acid (DMSA) scintigraphy. DMSA scintigraphy was performed at a median of 10 days after the start of treatment and was abnormal in 73 children (42%), equivocal in 29 (16%) and normal in 73 (42% Reflux was seen in 27% of all children and in 38% of the renal units that were abnormal at DMSA scintigraphy. A decreasing frequency of abnormalities at DMSA scintigraphy was seen within the first 14 days after the start of treatment. C-reactive protein and grade of reflux correlated significantly with abnormal DMSA studies. To demonstrate renal involvement in acute Urinary Tract Infection, DMSA scintigraphy should be performed within days after the start of treatment. It is noteworthy that reflux was seen in less than half of renal units with abnormal DMSA scintigraphy.
Eira Stokland - One of the best experts on this subject based on the ideXlab platform.
-
relationship among vesicoureteral reflux Urinary Tract Infection and renal damage in children
The Journal of Urology, 2007Co-Authors: Svante Swerkersson, U Jodal, Rune Sixt, Eira Stokland, Sverker HanssonAbstract:Purpose: We studied the relationship among vesicoureteral reflux, Urinary Tract Infection and permanent renal damage in children.Materials and Methods: We retrospectively analyzed 303 children younger than 2 years with a first time, nonobstructive, culture verified Urinary Tract Infection. The protocol included ultrasonography and voiding cystourethrography within 3 months after Urinary Tract Infection, and 99mtechnetium dimercapto-succinic acid scintigraphy after 1 to 2 years.Results: Vesicoureteral reflux was found in 36 of 163 boys (22%) and in 44 of 140 girls (31%). Of the 303 patients 80 (26%) had permanent renal damage according to dimercapto-succinic acid scintigraphy. The rate of abnormality increased significantly with grade of vesicoureteral reflux in boys and girls. The relative risk of renal damage was significantly increased in patients with vesicoureteral reflux grade II and higher. Maximum C-reactive protein concentration, maximum temperature during Urinary Tract Infection, presence of vesi...
-
renal damage one year after first Urinary Tract Infection role of dimercaptosuccinic acid scintigraphy
The Journal of Pediatrics, 1996Co-Authors: Eira Stokland, U Jodal, Mikael Hellstrom, Bo Jacobsson, Rune SixtAbstract:AbsTract OBJECTIVE: The aim of this study was to determine whether age, C-reactive protein (CRP), body temperature, or results of voiding cystourethrography at diagnosis of first-time symptomatic Urinary Tract Infection could predict the risk of renal damage as evaluated by dimercaptosuccinic acid (DMSA) scintigraphy performed 1 year after the Infection. DESIGN: The study included 157 children (median age, 0.4 year, range, 5 days to 5.8 years) with first-time symptomatic Urinary Tract Infection. In children 1 year of age or older, a body temperature of 38.5° C or higher was necessary for inclusion. CRP and body temperature were measured at the time of Infection, and voiding cystourethrography was performed shortly thereafter. DMSA scintigraphy was performed 1 year later in all children. RESULTS: After 1 year, 59 (38%) of the 157 children had renal damage as evaluated by DMSA scintigraphy, and of these, 28 (47%) had reflux. There was a positive correlation between renal damage and CRP, body temperature, and reflux. Children with high levels of CRP, high fever, and dilating reflux had a risk of renal damage up to 10 times higher than children with normal or slightly elevated CRP levels, no or mild fever, and no reflux. CONCLUSION: CRP concentration and body temperature at the index Infection, in combination with the results of voiding cystourethrography, are useful in classifying children at high and low risk of scintigraphic renal damage 1 year after Urinary Tract Infection. (J Pediatr 1996;129:815-20)
-
early 99mtc dimercaptosuccinic acid dmsa scintigraphy in symptomatic first time Urinary Tract Infection
Acta Paediatrica, 1996Co-Authors: Eira Stokland, U Jodal, Mikael Hellstrom, Bo Jacobsson, Pia Lundgren, Rune SixtAbstract:During a 2 year period, 175 children below 6 years of age (median 0.4 year) with non-obstructive symptomatic Urinary Tract Infection were studied by 99m Tc dimercaptosuccinic acid (DMSA) scintigraphy. DMSA scintigraphy was performed at a median of 10 days after the start of treatment and was abnormal in 73 children (42%), equivocal in 29 (16%) and normal in 73 (42% Reflux was seen in 27% of all children and in 38% of the renal units that were abnormal at DMSA scintigraphy. A decreasing frequency of abnormalities at DMSA scintigraphy was seen within the first 14 days after the start of treatment. C-reactive protein and grade of reflux correlated significantly with abnormal DMSA studies. To demonstrate renal involvement in acute Urinary Tract Infection, DMSA scintigraphy should be performed within days after the start of treatment. It is noteworthy that reflux was seen in less than half of renal units with abnormal DMSA scintigraphy.
Svante Swerkersson - One of the best experts on this subject based on the ideXlab platform.
-
the swedish reflux trial in children iii Urinary Tract Infection pattern
The Journal of Urology, 2010Co-Authors: Per Brandstrom, Svante Swerkersson, U Jodal, Elisabeth Esbjorner, Maria Herthelius, Sverker HanssonAbstract:Purpose: We evaluated the difference in the febrile Urinary Tract Infection rate in small children with dilating vesicoureteral reflux randomly allocated to 3 management alternatives, including antibiotic prophylaxis, endoscopic treatment or surveillance only as the control.Materials and Methods: At 23 centers a total of 203 children were included in the study, including 128 girls and 75 boys 1 to younger than 2 years. Vesicoureteral reflux grade III in 126 cases and IV in 77 was detected after a febrile Urinary Tract Infection (194) after prenatal screening (9). Voiding cystourethrography and dimercapto-succinic acid scintigraphy were done before randomization and after 2 years. The febrile Urinary Tract Infection rate was analyzed by the intent to treat principle.Results: We noted a total of 67 febrile recurrences in 42 girls and a total of 8 in 7 boys (p = 0.0001). There was a difference in the recurrence rate among treatment groups in girls with febrile Infection in 8 of 43 (19%) on prophylaxis, 10 of...
-
relationship among vesicoureteral reflux Urinary Tract Infection and renal damage in children
The Journal of Urology, 2007Co-Authors: Svante Swerkersson, U Jodal, Rune Sixt, Eira Stokland, Sverker HanssonAbstract:Purpose: We studied the relationship among vesicoureteral reflux, Urinary Tract Infection and permanent renal damage in children.Materials and Methods: We retrospectively analyzed 303 children younger than 2 years with a first time, nonobstructive, culture verified Urinary Tract Infection. The protocol included ultrasonography and voiding cystourethrography within 3 months after Urinary Tract Infection, and 99mtechnetium dimercapto-succinic acid scintigraphy after 1 to 2 years.Results: Vesicoureteral reflux was found in 36 of 163 boys (22%) and in 44 of 140 girls (31%). Of the 303 patients 80 (26%) had permanent renal damage according to dimercapto-succinic acid scintigraphy. The rate of abnormality increased significantly with grade of vesicoureteral reflux in boys and girls. The relative risk of renal damage was significantly increased in patients with vesicoureteral reflux grade II and higher. Maximum C-reactive protein concentration, maximum temperature during Urinary Tract Infection, presence of vesi...
