Urinary Tract Malformation

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E. Le Gall - One of the best experts on this subject based on the ideXlab platform.

  • Diagnosis of fetal Urinary Tract Malformations: prenatal management and postnatal outcome.
    Prenatal Diagnosis, 2011
    Co-Authors: A. Ryckewaert-d'halluin, G. Le Bouar, Sylvie Odent, J. Milon, Dominique D'hervé, Josette Lucas, Florence Rouget, Philippe Loget, Patrice Poulain, E. Le Gall
    Abstract:

    OBJECTIVE: To evaluate prenatal management and to define the criteria of gravity for accurate assessment of the renal and overall prognosis of fetuses presenting Malformations of the Urinary Tract. METHODS: We carried out a retrospective study of 127 cases of Urinary Tract Malformation. We carried out descriptive statistical and univariate analyses as a function of severity criteria and the outcome of pregnancy. RESULTS: One-third of fetuses presented associated extrarenal Malformations and 10% of the karyotypes were abnormal. There were more abortions in case of decrease in amniotic fluid volume (p < 0.001), extent of renal damage (p < 0.05), presence of associated extrarenal Malformations (p < 0.05), early diagnosis of the Malformation (p < 0.001) and presence of chromosomal syndrome (p = 0.01). In our study, there was an excellent correlation between prenatal data and pathological findings for the fetus following abortions for medical reasons or obtained during the surveillance of live-born children. Fetal biochemistry made very little contribution. CONCLUSION: In cases of Urinary Tract Malformation, this work confirms the need for regular and frequent ultrasound scans, checking for the echographic factors indicative of gravity and for adapted karyotyping. It also demonstrates that pluridisciplinary management is necessary for the prenatal evaluation of renal and overall fetal prognosis.

  • Diagnosis of fetal Urinary Tract Malformations: prenatal management and postnatal outcome
    Prenatal Diagnosis, 2011
    Co-Authors: A. Ryckewaert-d'halluin, G. Le Bouar, Sylvie Odent, J. Milon, Dominique D'hervé, Josette Lucas, Florence Rouget, Philippe Loget, Patrice Poulain, E. Le Gall
    Abstract:

    Objective To evaluate prenatal management and to define the criteria of gravity for accurate assessment of the renal and overall prognosis of fetuses presenting Malformations of the Urinary Tract. Methods We carried out a retrospective study of 127 cases of Urinary Tract Malformation. We carried out descriptive statistical and univariate analyses as a function of severity criteria and the outcome of pregnancy. Results One-third of fetuses presented associated extrarenal Malformations and 10% of the karyotypes were abnormal. There were more abortions in case of decrease in amniotic fluid volume (p < 0.001), extent of renal damage (p < 0.05), presence of associated extrarenal Malformations (p < 0.05), early diagnosis of the Malformation (p < 0.001) and presence of chromosomal syndrome (p = 0.01). In our study, there was an excellent correlation between prenatal data and pathological findings for the fetus following abortions for medical reasons or obtained during the surveillance of live-born children. Fetal biochemistry made very little contribution. Conclusion In cases of Urinary Tract Malformation, this work confirms the need for regular and frequent ultrasound scans, checking for the echographic factors indicative of gravity and for adapted karyotyping. It also demonstrates that pluridisciplinary management is necessary for the prenatal evaluation of renal and overall fetal prognosis. Copyright © 2011 John Wiley & Sons, Ltd.

Carlo Vicentini - One of the best experts on this subject based on the ideXlab platform.

  • ejaculatory duct obstruction caused by a right giant seminal vesicle with an ipsilateral upper Urinary Tract agenesia an embryologic Malformation
    Fertility and Sterility, 2008
    Co-Authors: Gianna Pace, Giuseppe Paradiso Galatioto, Luana Guala, Guido Ranieri, Carlo Vicentini
    Abstract:

    Objective To report our experience with TURED in infertile men with EDO associated with abnormal development of the mesonephric or Wolffian duct, causing a contemporary Malformation of the ipsilateral upper Urinary Tract. Design Retrospective clinical study. Setting Infertile men in an hospital environment. Patient(s) Seven patients affected by Zinner syndrome, from March to September 2005, were selected. Intervention(s) Underwent TURED. Main Outcome Measure(s) Semen analysis, endocrine profile, transrectal ultrasonography and seminal vesicles aspiration, excretory urography, computerized tomography (CT), or magnetic resonance imaging (MRI). Result(s) Before surgery, the patients experienced a decreased intensity and force of ejaculation and a low motile sperm count. The detection of the ipsilateral upper Urinary Tract Malformation by the patients was incidental. After surgery, all patients reported having a projectile ejaculation, an increase in the average postoperative volume, and of the total motile sperm count. Conclusion(s) A seminal vesicle cyst combined with ipsilateral renal agenesis, described as Zinner syndrome, is a rare urological anomaly. It is frequently asymptomatic or else characterized by infertility, symptoms of bladder irritation, or pain in the scrotum and perineum. In selected patients, TURED can improve semen quality with subsequent ability to impregnate. The upper Urinary Tract Malformation should be treated in symptomatic cases only.

A. Calabro - One of the best experts on this subject based on the ideXlab platform.

A. Ryckewaert-d'halluin - One of the best experts on this subject based on the ideXlab platform.

  • Diagnosis of fetal Urinary Tract Malformations: prenatal management and postnatal outcome.
    Prenatal Diagnosis, 2011
    Co-Authors: A. Ryckewaert-d'halluin, G. Le Bouar, Sylvie Odent, J. Milon, Dominique D'hervé, Josette Lucas, Florence Rouget, Philippe Loget, Patrice Poulain, E. Le Gall
    Abstract:

    OBJECTIVE: To evaluate prenatal management and to define the criteria of gravity for accurate assessment of the renal and overall prognosis of fetuses presenting Malformations of the Urinary Tract. METHODS: We carried out a retrospective study of 127 cases of Urinary Tract Malformation. We carried out descriptive statistical and univariate analyses as a function of severity criteria and the outcome of pregnancy. RESULTS: One-third of fetuses presented associated extrarenal Malformations and 10% of the karyotypes were abnormal. There were more abortions in case of decrease in amniotic fluid volume (p < 0.001), extent of renal damage (p < 0.05), presence of associated extrarenal Malformations (p < 0.05), early diagnosis of the Malformation (p < 0.001) and presence of chromosomal syndrome (p = 0.01). In our study, there was an excellent correlation between prenatal data and pathological findings for the fetus following abortions for medical reasons or obtained during the surveillance of live-born children. Fetal biochemistry made very little contribution. CONCLUSION: In cases of Urinary Tract Malformation, this work confirms the need for regular and frequent ultrasound scans, checking for the echographic factors indicative of gravity and for adapted karyotyping. It also demonstrates that pluridisciplinary management is necessary for the prenatal evaluation of renal and overall fetal prognosis.

  • Diagnosis of fetal Urinary Tract Malformations: prenatal management and postnatal outcome
    Prenatal Diagnosis, 2011
    Co-Authors: A. Ryckewaert-d'halluin, G. Le Bouar, Sylvie Odent, J. Milon, Dominique D'hervé, Josette Lucas, Florence Rouget, Philippe Loget, Patrice Poulain, E. Le Gall
    Abstract:

    Objective To evaluate prenatal management and to define the criteria of gravity for accurate assessment of the renal and overall prognosis of fetuses presenting Malformations of the Urinary Tract. Methods We carried out a retrospective study of 127 cases of Urinary Tract Malformation. We carried out descriptive statistical and univariate analyses as a function of severity criteria and the outcome of pregnancy. Results One-third of fetuses presented associated extrarenal Malformations and 10% of the karyotypes were abnormal. There were more abortions in case of decrease in amniotic fluid volume (p < 0.001), extent of renal damage (p < 0.05), presence of associated extrarenal Malformations (p < 0.05), early diagnosis of the Malformation (p < 0.001) and presence of chromosomal syndrome (p = 0.01). In our study, there was an excellent correlation between prenatal data and pathological findings for the fetus following abortions for medical reasons or obtained during the surveillance of live-born children. Fetal biochemistry made very little contribution. Conclusion In cases of Urinary Tract Malformation, this work confirms the need for regular and frequent ultrasound scans, checking for the echographic factors indicative of gravity and for adapted karyotyping. It also demonstrates that pluridisciplinary management is necessary for the prenatal evaluation of renal and overall fetal prognosis. Copyright © 2011 John Wiley & Sons, Ltd.

Gianna Pace - One of the best experts on this subject based on the ideXlab platform.

  • ejaculatory duct obstruction caused by a right giant seminal vesicle with an ipsilateral upper Urinary Tract agenesia an embryologic Malformation
    Fertility and Sterility, 2008
    Co-Authors: Gianna Pace, Giuseppe Paradiso Galatioto, Luana Guala, Guido Ranieri, Carlo Vicentini
    Abstract:

    Objective To report our experience with TURED in infertile men with EDO associated with abnormal development of the mesonephric or Wolffian duct, causing a contemporary Malformation of the ipsilateral upper Urinary Tract. Design Retrospective clinical study. Setting Infertile men in an hospital environment. Patient(s) Seven patients affected by Zinner syndrome, from March to September 2005, were selected. Intervention(s) Underwent TURED. Main Outcome Measure(s) Semen analysis, endocrine profile, transrectal ultrasonography and seminal vesicles aspiration, excretory urography, computerized tomography (CT), or magnetic resonance imaging (MRI). Result(s) Before surgery, the patients experienced a decreased intensity and force of ejaculation and a low motile sperm count. The detection of the ipsilateral upper Urinary Tract Malformation by the patients was incidental. After surgery, all patients reported having a projectile ejaculation, an increase in the average postoperative volume, and of the total motile sperm count. Conclusion(s) A seminal vesicle cyst combined with ipsilateral renal agenesis, described as Zinner syndrome, is a rare urological anomaly. It is frequently asymptomatic or else characterized by infertility, symptoms of bladder irritation, or pain in the scrotum and perineum. In selected patients, TURED can improve semen quality with subsequent ability to impregnate. The upper Urinary Tract Malformation should be treated in symptomatic cases only.