The Experts below are selected from a list of 162 Experts worldwide ranked by ideXlab platform
J Palou - One of the best experts on this subject based on the ideXlab platform.
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diagnosis risk factors and outcome of urethral recurrences following radical cystectomy for bladder cancer in 729 male patients
European Urology, 2008Co-Authors: J Huguet, J Palou, Vanesa Monllau, S Sabate, O Rodriguezfaba, Ferran Algaba, Humberto VillavicencioAbstract:AbsTract Objectives We evaluated incidence, diagnosis, risk factors, and outcome of urethral recurrences (URs) following radical cystectomy in men with bladder urothelial carcinoma (UC). Methods Between 1978 and 2003, a total of 729 male patients underwent radical cystectomy for UC. We determined UR presentation mode and diagnosis. UR was analysed by multivariate analyses according to clinical and pathological risk factors . We evaluated the relative influence of bladder versus urethral pathology on overall survival. Results A total of 34 URs (4.6%) were identified. Previous history of non–muscle-invasive bladder cancer (NMIBC) ( p =0.005), NMIBC pathological subgroup (pTis, pTa, pT1) ( p =0.038) and prostate Tumor involvement ( p =0.0001) in cystectomy specimens were independent predictors of UR. URs developed in 5 (2.2%) of 219 cases with orthotopic diversion and in 29 (5.6%) of 510 with cutaneous diversion ( p =0.073). The difference could be explained by patient selection. Cutaneous diversion group had more patients at risk of UR: more cases with prostate Tumor involvement ( p =0.026) and with a history of NMIBC ( p =0.009). Neither bladder nor urethral pathology showed any superiority as a predictor of overall survival. Conclusions Previous history of NMIBC, and also NMIBC and prostate Tumor involvement in cystectomy specimen were predictors of UR. The lower incidence of UR in patients with orthotopic diversion could be a result of patient selection. Bladder Tumor, UR, and even an upper Urinary Tract Tumor could have been the cause of death in these patients.
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multivariate analysis of clinical parameters of synchronous primary superficial bladder cancer and upper Urinary Tract Tumor
The Journal of Urology, 2005Co-Authors: J Palou, J. Segarra, Federico Rodriguezrubio, J Huguet, M J Ribal, Antonio Alcaraz, H VillavicencioAbstract:ABSTractPurpose: We determined the incidence and characteristic of synchronous upper Urinary Tract Tumors (UUTTs) in patients with primary superficial bladder carcinoma and evaluated the characteristics of bladder Tumors related to UUTTs.Materials and Methods: We performed a retrospective study of 1,529 patients with primary superficial bladder carcinoma who underwent initial examination of the upper Urinary Tract with excretory urography. Data were analyzed by multivariate analysis using logistic regression. Variables evaluated and related to the incidence of UUTT were multiplicity, carcinoma in situ, bladder Tumor size, localization of Tumor in the bladder, and Tumor grade and stage.Results: A total of 28 patients (1.8%) had simultaneous bladder Tumor and UUTT. UUTTs showed no preferred location and 17.9% were multiple. Of UUTTs 46% were invasive and almost 87% were grade 2 or 3. The only significant variable related to UUTT was bladder Tumor in the trigone (RR 5.8, 95% IC 2.18 to 15.9, p <0.0005). Of 1...
J. Vicente-rodríguez - One of the best experts on this subject based on the ideXlab platform.
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Upper Urinary Tract Tumors after primary superficial bladder Tumors: prognostic factors and risk groups.
The Journal of urology, 2000Co-Authors: F. Millán-rodríguez, G. Chéchile-toniolo, J. Salvador-bayarri, J. Huguet-pérez, J. Vicente-rodríguezAbstract:Purpose: We evaluated the prognostic factors of primary superficial bladder cancer that may predict a metachronous upper Urinary Tract Tumor. We also determined whether the incidence of upper Urinary Tract disease varies according to risk group based on primary superficial bladder Tumor classification.Materials and Methods: We studied disease evolution in a cohort of 1,529 patients with a primary superficial bladder Tumor. To determine the prognostic factors of upper Urinary Tract cancer we performed multivariate analysis using Cox regression. Independent variables were grade, T stage, multiplicity, Tumor size, carcinoma in situ association, previous or synchronous upper Urinary Tract Tumor and intravesical instillation. We also performed the chi-square test and Kaplan-Meier survival analysis to assess the variable incidence of upper Urinary Tract Tumors according to primary superficial bladder Tumor risk group classification.Results: The incidence of upper Urinary Tract cancer was 2.6%. The only factor p...
Humberto Villavicencio - One of the best experts on this subject based on the ideXlab platform.
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diagnosis risk factors and outcome of urethral recurrences following radical cystectomy for bladder cancer in 729 male patients
European Urology, 2008Co-Authors: J Huguet, J Palou, Vanesa Monllau, S Sabate, O Rodriguezfaba, Ferran Algaba, Humberto VillavicencioAbstract:AbsTract Objectives We evaluated incidence, diagnosis, risk factors, and outcome of urethral recurrences (URs) following radical cystectomy in men with bladder urothelial carcinoma (UC). Methods Between 1978 and 2003, a total of 729 male patients underwent radical cystectomy for UC. We determined UR presentation mode and diagnosis. UR was analysed by multivariate analyses according to clinical and pathological risk factors . We evaluated the relative influence of bladder versus urethral pathology on overall survival. Results A total of 34 URs (4.6%) were identified. Previous history of non–muscle-invasive bladder cancer (NMIBC) ( p =0.005), NMIBC pathological subgroup (pTis, pTa, pT1) ( p =0.038) and prostate Tumor involvement ( p =0.0001) in cystectomy specimens were independent predictors of UR. URs developed in 5 (2.2%) of 219 cases with orthotopic diversion and in 29 (5.6%) of 510 with cutaneous diversion ( p =0.073). The difference could be explained by patient selection. Cutaneous diversion group had more patients at risk of UR: more cases with prostate Tumor involvement ( p =0.026) and with a history of NMIBC ( p =0.009). Neither bladder nor urethral pathology showed any superiority as a predictor of overall survival. Conclusions Previous history of NMIBC, and also NMIBC and prostate Tumor involvement in cystectomy specimen were predictors of UR. The lower incidence of UR in patients with orthotopic diversion could be a result of patient selection. Bladder Tumor, UR, and even an upper Urinary Tract Tumor could have been the cause of death in these patients.
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Protocolo de ureterorenoscopia en el diagnóstico y tratamiento del carcinoma urotelial del tramo urinario superior
Archivos espanoles de urologia, 2004Co-Authors: Juan Palou, J. Vicente, J. Segarra, Jorge Huguet, José Salvador, Humberto VillavicencioAbstract:Since Perez-Castro and Martinez-Pineiro initiated diagnostic and therapeutic ureteroscopy this technique has gained a place in the management of upper Urinary Tract Tumors. Improvement of the equipment (rigid and flexible), better diagnosis and knowledge of outcomes and allows to treat a group of patients with transitional cell carcinoma of the ureter and pelvis by the conservative retrograde technique. In this article, we present an overview of indications and management of the upper Urinary Tract Tumor by ureteroscopy.
J Huguet - One of the best experts on this subject based on the ideXlab platform.
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diagnosis risk factors and outcome of urethral recurrences following radical cystectomy for bladder cancer in 729 male patients
European Urology, 2008Co-Authors: J Huguet, J Palou, Vanesa Monllau, S Sabate, O Rodriguezfaba, Ferran Algaba, Humberto VillavicencioAbstract:AbsTract Objectives We evaluated incidence, diagnosis, risk factors, and outcome of urethral recurrences (URs) following radical cystectomy in men with bladder urothelial carcinoma (UC). Methods Between 1978 and 2003, a total of 729 male patients underwent radical cystectomy for UC. We determined UR presentation mode and diagnosis. UR was analysed by multivariate analyses according to clinical and pathological risk factors . We evaluated the relative influence of bladder versus urethral pathology on overall survival. Results A total of 34 URs (4.6%) were identified. Previous history of non–muscle-invasive bladder cancer (NMIBC) ( p =0.005), NMIBC pathological subgroup (pTis, pTa, pT1) ( p =0.038) and prostate Tumor involvement ( p =0.0001) in cystectomy specimens were independent predictors of UR. URs developed in 5 (2.2%) of 219 cases with orthotopic diversion and in 29 (5.6%) of 510 with cutaneous diversion ( p =0.073). The difference could be explained by patient selection. Cutaneous diversion group had more patients at risk of UR: more cases with prostate Tumor involvement ( p =0.026) and with a history of NMIBC ( p =0.009). Neither bladder nor urethral pathology showed any superiority as a predictor of overall survival. Conclusions Previous history of NMIBC, and also NMIBC and prostate Tumor involvement in cystectomy specimen were predictors of UR. The lower incidence of UR in patients with orthotopic diversion could be a result of patient selection. Bladder Tumor, UR, and even an upper Urinary Tract Tumor could have been the cause of death in these patients.
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multivariate analysis of clinical parameters of synchronous primary superficial bladder cancer and upper Urinary Tract Tumor
The Journal of Urology, 2005Co-Authors: J Palou, J. Segarra, Federico Rodriguezrubio, J Huguet, M J Ribal, Antonio Alcaraz, H VillavicencioAbstract:ABSTractPurpose: We determined the incidence and characteristic of synchronous upper Urinary Tract Tumors (UUTTs) in patients with primary superficial bladder carcinoma and evaluated the characteristics of bladder Tumors related to UUTTs.Materials and Methods: We performed a retrospective study of 1,529 patients with primary superficial bladder carcinoma who underwent initial examination of the upper Urinary Tract with excretory urography. Data were analyzed by multivariate analysis using logistic regression. Variables evaluated and related to the incidence of UUTT were multiplicity, carcinoma in situ, bladder Tumor size, localization of Tumor in the bladder, and Tumor grade and stage.Results: A total of 28 patients (1.8%) had simultaneous bladder Tumor and UUTT. UUTTs showed no preferred location and 17.9% were multiple. Of UUTTs 46% were invasive and almost 87% were grade 2 or 3. The only significant variable related to UUTT was bladder Tumor in the trigone (RR 5.8, 95% IC 2.18 to 15.9, p <0.0005). Of 1...
H Villavicencio - One of the best experts on this subject based on the ideXlab platform.
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multivariate analysis of clinical parameters of synchronous primary superficial bladder cancer and upper Urinary Tract Tumor
The Journal of Urology, 2005Co-Authors: J Palou, J. Segarra, Federico Rodriguezrubio, J Huguet, M J Ribal, Antonio Alcaraz, H VillavicencioAbstract:ABSTractPurpose: We determined the incidence and characteristic of synchronous upper Urinary Tract Tumors (UUTTs) in patients with primary superficial bladder carcinoma and evaluated the characteristics of bladder Tumors related to UUTTs.Materials and Methods: We performed a retrospective study of 1,529 patients with primary superficial bladder carcinoma who underwent initial examination of the upper Urinary Tract with excretory urography. Data were analyzed by multivariate analysis using logistic regression. Variables evaluated and related to the incidence of UUTT were multiplicity, carcinoma in situ, bladder Tumor size, localization of Tumor in the bladder, and Tumor grade and stage.Results: A total of 28 patients (1.8%) had simultaneous bladder Tumor and UUTT. UUTTs showed no preferred location and 17.9% were multiple. Of UUTTs 46% were invasive and almost 87% were grade 2 or 3. The only significant variable related to UUTT was bladder Tumor in the trigone (RR 5.8, 95% IC 2.18 to 15.9, p <0.0005). Of 1...
