The Experts below are selected from a list of 54 Experts worldwide ranked by ideXlab platform
Virginia A. Livolsi - One of the best experts on this subject based on the ideXlab platform.
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Endometrial metaplasia of the Uterine Endocervix.
Archives of Pathology & Laboratory Medicine, 1993Co-Authors: I-tien Yeh, Mary P. Bronner, Virginia A. LivolsiAbstract:: We report a case of endometrial metaplasia of the Endocervix, which was associated with tubal and squamous metaplasias. The similarity to normal endometrial glands and its benign nature should be recognized, and over-diagnosis of endocervical glandular dysplasia should be avoided.
Roberto P. Revoltella - One of the best experts on this subject based on the ideXlab platform.
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Cytoarchitecture modifications of the human Uterine endocervical mucosa in long-term three-dimensional organotypic culture.
Pathology research and practice, 2005Co-Authors: Monica Michelini, Alfredo Rosellini, Václav Mandys, Tommaso Simoncini, Roberto P. RevoltellaAbstract:Abstract We assayed the effects of phenol red (pr), estrogen (Es), and progesterone (Pg) in three-dimensional organotypic cultures of human Uterine Endocervix. Small intact fragments deposited on sponges submerged in DMEM with 10% fetal bovine serum were cultured in three different conditions: with pr (DMEMpr+), without pr (DMEMpr−), and without pr but with the addition of physiological concentrations of Es and Pg [DMEMpr−(Es+Pg)]. Cell viability and cellular responses were assayed after 4, 10, and 21 days using immunohistochemistry for the expression and distribution of the following markers: mucins and mucopolysaccharides (PAS staining), pan-cytokeratins (AE1/AE3), CK19, p63, Ki-67, vimentin, estrogen receptor-α (ER-α), and progesterone receptor (PR). The fragments cultivated in DMEMpr+ showed a cuboidal, poorly differentiated epithelial phenotype and signs of stroma degeneration. In DMEMpr−, both tissue architecture and cellular heterogeneity were much better preserved: epithelial cells showed a more columnar shape, and stroma was very well conserved, maintaining cell density. The addition of Es and Pg further improved the histology and physiology of the fragments: in DMEMpr−(Es+Pg), epithelial cells retained a columnar shape, secreted mucins, and formed areas of squamous hyperplasia.
I-tien Yeh - One of the best experts on this subject based on the ideXlab platform.
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Endometrial metaplasia of the Uterine Endocervix.
Archives of Pathology & Laboratory Medicine, 1993Co-Authors: I-tien Yeh, Mary P. Bronner, Virginia A. LivolsiAbstract:: We report a case of endometrial metaplasia of the Endocervix, which was associated with tubal and squamous metaplasias. The similarity to normal endometrial glands and its benign nature should be recognized, and over-diagnosis of endocervical glandular dysplasia should be avoided.
Monica Michelini - One of the best experts on this subject based on the ideXlab platform.
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Cytoarchitecture modifications of the human Uterine endocervical mucosa in long-term three-dimensional organotypic culture.
Pathology research and practice, 2005Co-Authors: Monica Michelini, Alfredo Rosellini, Václav Mandys, Tommaso Simoncini, Roberto P. RevoltellaAbstract:Abstract We assayed the effects of phenol red (pr), estrogen (Es), and progesterone (Pg) in three-dimensional organotypic cultures of human Uterine Endocervix. Small intact fragments deposited on sponges submerged in DMEM with 10% fetal bovine serum were cultured in three different conditions: with pr (DMEMpr+), without pr (DMEMpr−), and without pr but with the addition of physiological concentrations of Es and Pg [DMEMpr−(Es+Pg)]. Cell viability and cellular responses were assayed after 4, 10, and 21 days using immunohistochemistry for the expression and distribution of the following markers: mucins and mucopolysaccharides (PAS staining), pan-cytokeratins (AE1/AE3), CK19, p63, Ki-67, vimentin, estrogen receptor-α (ER-α), and progesterone receptor (PR). The fragments cultivated in DMEMpr+ showed a cuboidal, poorly differentiated epithelial phenotype and signs of stroma degeneration. In DMEMpr−, both tissue architecture and cellular heterogeneity were much better preserved: epithelial cells showed a more columnar shape, and stroma was very well conserved, maintaining cell density. The addition of Es and Pg further improved the histology and physiology of the fragments: in DMEMpr−(Es+Pg), epithelial cells retained a columnar shape, secreted mucins, and formed areas of squamous hyperplasia.
Mary P. Bronner - One of the best experts on this subject based on the ideXlab platform.
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Endometrial metaplasia of the Uterine Endocervix.
Archives of Pathology & Laboratory Medicine, 1993Co-Authors: I-tien Yeh, Mary P. Bronner, Virginia A. LivolsiAbstract:: We report a case of endometrial metaplasia of the Endocervix, which was associated with tubal and squamous metaplasias. The similarity to normal endometrial glands and its benign nature should be recognized, and over-diagnosis of endocervical glandular dysplasia should be avoided.
