The Experts below are selected from a list of 294 Experts worldwide ranked by ideXlab platform
Jung-yul Park - One of the best experts on this subject based on the ideXlab platform.
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What are MRI findings of Spine Benign Metastasizing Leiomyoma? Case report with literature review
European Spine Journal, 2015Co-Authors: Jung-yul ParkAbstract:Introduction Benign Metastasizing Leiomyoma (BML) is a rare disease that results from metastasis of Uterine leiomyoma to distant sites with benign pathologic features. Spine BML is very rare so the information of its features and pathophysiology is seldom known. Materials and Methods We experienced a case of 42-year-old woman who presented with right buttock and leg pain with paresthesia. She had a surgical history of Uterine Myomectomy. Magnetic resonance imaging (MRI) of the lumbar spine revealed a well-circumscribed mass lesion in the posterior compartment of the L4 vertebral body, with extension into the ventral epidural space and both foramina. The mass showed hypointensity on T1-, T2-weighted images and strong homogeneous enhancement on gadolinium enhanced T1-weighted images. Tumor removal was conducted, and permanent biopsy revealed the mass as leiomyoma. Nine previous spine BML reports, which are known for all, were reviewed along with our case. We collated the clinical information and MRI findings of spine BML to figure out its common denominators. Results Premenopausal women, previous history of Uterine myoma, Myomectomy/hysterectomy, and lung BML seemed to be predisposing clinical factors. For the imaging findings, posterior vertebral body invasion with bony destruction, neural foramen invasion, and canal encroachment were shown as common denominators. Especially in MRI findings, low T1 and T2 signal intensities with strong homogeneous enhancement were their common features. Conclusion We gathered the fragmentary information of the spine BML for the first time, especially the MRI findings. Although spine BML is rare, it surely exists. Accordingly, spine surgeons should be suspicious of spine BML given its typical clinical history and MRI findings.
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What are MRI findings of Spine Benign Metastasizing Leiomyoma? Case report with literature review.
European spine journal : official publication of the European Spine Society the European Spinal Deformity Society and the European Section of the Cerv, 2015Co-Authors: Jung-yul ParkAbstract:Benign Metastasizing Leiomyoma (BML) is a rare disease that results from metastasis of Uterine leiomyoma to distant sites with benign pathologic features. Spine BML is very rare so the information of its features and pathophysiology is seldom known. We experienced a case of 42-year-old woman who presented with right buttock and leg pain with paresthesia. She had a surgical history of Uterine Myomectomy. Magnetic resonance imaging (MRI) of the lumbar spine revealed a well-circumscribed mass lesion in the posterior compartment of the L4 vertebral body, with extension into the ventral epidural space and both foramina. The mass showed hypointensity on T1-, T2-weighted images and strong homogeneous enhancement on gadolinium enhanced T1-weighted images. Tumor removal was conducted, and permanent biopsy revealed the mass as leiomyoma. Nine previous spine BML reports, which are known for all, were reviewed along with our case. We collated the clinical information and MRI findings of spine BML to figure out its common denominators. Premenopausal women, previous history of Uterine myoma, Myomectomy/hysterectomy, and lung BML seemed to be predisposing clinical factors. For the imaging findings, posterior vertebral body invasion with bony destruction, neural foramen invasion, and canal encroachment were shown as common denominators. Especially in MRI findings, low T1 and T2 signal intensities with strong homogeneous enhancement were their common features. We gathered the fragmentary information of the spine BML for the first time, especially the MRI findings. Although spine BML is rare, it surely exists. Accordingly, spine surgeons should be suspicious of spine BML given its typical clinical history and MRI findings.
F. Sesti - One of the best experts on this subject based on the ideXlab platform.
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Uterine Myomectomy: Role of gasless laparoscopy in comparison with other minimally invasive approaches
Minimally Invasive Therapy & Allied Technologies, 2012Co-Authors: Francesco Sesti, F. Sesti, A. Pietropolli, Emilio PiccioneAbstract:Abstract Introduction: The aim of this review was to assess the role of gasless laparoscopy (GLM) in comparison with two other minimally invasive approaches to Myomectomy, CO2 laparoscopy (LM) and minilaparotomy (MM), focusing on the most recent randomized or prospective controlled studies. Material and methods: A computerized search was made of the Medline, Science Citation Index, Current Contents, Embase, and PubMed databases for English language publications from the first reports of GLM, LM, and MM in 1995 to 2010. The fifteen most recent randomized or prospective controlled studies were selected and analyzed considering the operative and postoperative parameters. Results: One randomized controlled, one multicenter controlled, three prospective studies about GLM, four randomized controlled studies and one prospective study about LM, four randomized controlled trials and one prospective study about MM were reviewed and analyzed. Discussion: GLM offers some advantages eliminating the adverse effects and...
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Isobaric gasless laparoscopy versus minilaparotomy in Uterine Myomectomy: a randomized trial
Surgical Endoscopy, 2008Co-Authors: F. Sesti, F. Capobianco, T. Capozzolo, A. Pietropolli, E. PiccioneAbstract:Background Isobaric gasless laparoscopy and minilaparotomy have been used as more recent minimally invasive approaches to Myomectomy. This randomized trial aimed to compare the surgical and immediate postoperative outcomes for Myomectomy performed by isobaric gasless laparoscopy with those for minilaparotomy. Methods A total of 100 patients with symptomatic Uterine myomas requiring Myomectomy were randomly allocated to the gasless laparoscopy group or the minilaparotomy group. The randomization procedure was based on a computer-generated list. The primary outcome was a comparison of the discharge times between the two procedures. A power calculation verified that more than 26 patients for each group was necessary to detect a difference of more than 24 h in discharge time with an alpha error level of 5% and a beta error of 80%. Continuous outcome variables were analyzed using the Student’s t -test. Discrete variables were analyzed with the chi-square test or Fisher’s exact test. A p value less than 0.05 was considered statistically significant. Results The mean discharge time was longer for minilaparotomy than for gasless laparoscopy (98.4 ± 1.4 vs 52.8 ± 1.6 h; p
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isobaric gasless laparoscopy versus minilaparotomy in Uterine Myomectomy a randomized trial
Surgical Endoscopy and Other Interventional Techniques, 2008Co-Authors: F. Sesti, F. Capobianco, T. Capozzolo, A. Pietropolli, Emilio PiccioneAbstract:Background Isobaric gasless laparoscopy and minilaparotomy have been used as more recent minimally invasive approaches to Myomectomy. This randomized trial aimed to compare the surgical and immediate postoperative outcomes for Myomectomy performed by isobaric gasless laparoscopy with those for minilaparotomy.
M D Bridges - One of the best experts on this subject based on the ideXlab platform.
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benign metastasizing leiomyoma responsive to megestrol case report and review of the literature
International Journal of Gynecological Cancer, 2005Co-Authors: G K Wentling, Bernd-uwe Sevin, X J Geiger, M D BridgesAbstract:. Wentling GK, Sevin B-U, Geiger XJ, Bridges MD. Benign metastasizing leiomyoma responsive to megestrol: case report and review of the literature. Int J Gynecol Cancer 2005;15:1213–1217. Benign metastasizing leiomyoma (BML) is an unusual condition typically treated by surgical resection and hormonal therapy. A 37-year-old woman presented with dyspnea 6 years after Uterine Myomectomy. Computed tomographic scans showed pelvic and right-sided lung masses. Total abdominal hysterectomy and right salpingo-oophorectomy revealed only leiomyomas and benign ovarian cysts. Thoracotomy revealed multiple nodules consistent with leiomyomas. Estrogen and progesterone receptors on lung and Uterine tissue were positive. A 21- × 18-mm residual area of neoplasm in the lung completely resolved 3 months after treatment with megestrol. The patient remains free of disease 3 years after lung resection. We present a rare case of BML in which the lung neoplasm responded to megestrol alone in the setting of intact ovarian function.
Emilio Piccione - One of the best experts on this subject based on the ideXlab platform.
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Uterine Myomectomy: Role of gasless laparoscopy in comparison with other minimally invasive approaches
Minimally Invasive Therapy & Allied Technologies, 2012Co-Authors: Francesco Sesti, F. Sesti, A. Pietropolli, Emilio PiccioneAbstract:Abstract Introduction: The aim of this review was to assess the role of gasless laparoscopy (GLM) in comparison with two other minimally invasive approaches to Myomectomy, CO2 laparoscopy (LM) and minilaparotomy (MM), focusing on the most recent randomized or prospective controlled studies. Material and methods: A computerized search was made of the Medline, Science Citation Index, Current Contents, Embase, and PubMed databases for English language publications from the first reports of GLM, LM, and MM in 1995 to 2010. The fifteen most recent randomized or prospective controlled studies were selected and analyzed considering the operative and postoperative parameters. Results: One randomized controlled, one multicenter controlled, three prospective studies about GLM, four randomized controlled studies and one prospective study about LM, four randomized controlled trials and one prospective study about MM were reviewed and analyzed. Discussion: GLM offers some advantages eliminating the adverse effects and...
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Multiple ectopic leiomyomas of the abdominal rectus muscles after gasless laparoscopic Uterine Myomectomy
Archives of Gynecology and Obstetrics, 2012Co-Authors: Francesco Sesti, Chiara Di Pietro, Antonio Capece, Emilio PiccioneAbstract:Purpose To describe and analyze the first case of multiple ectopic leiomyomas of the abdominal rectus muscles in a patient who had undergone gasless laparoscopic Uterine Myomectomy (GLM) 10 years before. Methods A 41-year-old woman, who had undergone GLM 10 years before, having presented multiple palpable masses of the abdominal wall, underwent minilaparotomic excision of six abdominal masses. Results Six round well-circumscribed masses of the abdominal rectus muscles, measuring, respectively, 3.8 × 1.7, 2.9 × 0.9, 0.8 × 0.5, 0.7 × 0.3, 10 × 0.8 and 0.5 × 0.4 cm, were excised. The major lesion was situated close to the right trocar site of the previous GLM, the other smaller tumors were located in the umbilical area and left abdominal region. On histopathologic examination, the abdominal lumps were categorized as leiomyoma. Conclusions Ectopic leiomyomatosis is an uncommon complication after GLM, and does not justify follow-up in all asymptomatic cases. However, the gynecologists should bear this unusual condition in mind, and inform the patients that leiomyoma fragments can grow in ectopic sites.
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Multiple ectopic leiomyomas of the abdominal rectus muscles after gasless laparoscopic Uterine Myomectomy.
Archives of Gynecology and Obstetrics, 2011Co-Authors: Francesco Sesti, Chiara Di Pietro, Antonio Capece, Emilio PiccioneAbstract:Purpose To describe and analyze the first case of multiple ectopic leiomyomas of the abdominal rectus muscles in a patient who had undergone gasless laparoscopic Uterine Myomectomy (GLM) 10 years before.
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isobaric gasless laparoscopy versus minilaparotomy in Uterine Myomectomy a randomized trial
Surgical Endoscopy and Other Interventional Techniques, 2008Co-Authors: F. Sesti, F. Capobianco, T. Capozzolo, A. Pietropolli, Emilio PiccioneAbstract:Background Isobaric gasless laparoscopy and minilaparotomy have been used as more recent minimally invasive approaches to Myomectomy. This randomized trial aimed to compare the surgical and immediate postoperative outcomes for Myomectomy performed by isobaric gasless laparoscopy with those for minilaparotomy.
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isobaric gasless laparoscopic Uterine Myomectomy an overview
European Journal of Obstetrics & Gynecology and Reproductive Biology, 2006Co-Authors: Francesco Sesti, Luigi Melgrati, Alfredo Damiani, Emilio PiccioneAbstract:The aim of this review has been to assess the usefulness and effectiveness of isobaric (gasless) laparoscopic Myomectomy using a subcutaneous abdominal wall lifting system, and to evaluate the advantages and disadvantages of this technique in comparison with the conventional laparoscopic Myomectomy using pneumoperitoneum. Laparoscopy using CO2 is more frequently employed for small or medium-sized myomas. Furthermore, multiple myomectomies (3 myomas per patient) are performed rarely. Gasless laparoscopy permits the removal of large intramural myomas overcoming the difficulties associated with laparoscopic Myomectomy using pneumoperitoneum. It appears to offer several advantages over conventional laparoscopy, such as elimination of the adverse effects and potential risks associated with CO2 insufflation; use of conventional laparotomy instruments that facilitate several steps of the procedure; reduced operative times and costs. Indeed, this procedure associates the advantages of laparoscopy and minimal access surgery with those of using the laparotomic instruments that are more reliable for Uterine closure. The only advantage of the laparoscopy with pneumoperitoneum is the tamponade effect generated by the gas on the small vessels, thus reducing intraoperative bleeding. Laparoscopic Myomectomy using CO2 remains the preferred minimally invasive approach for small and medium-sized myomas and when the total number of myomas removed does not exceed 2 or 3. Gasless laparoscopic Myomectomy could be mainly indicated for removal of large intramural myomas (8 cm) and/or for multiple myomectomies (3 myomas per patient). Anyhow, further controlled studies are needed to evaluate entirely their respective indications. # 2006 Elsevier Ireland Ltd. All rights reserved.
A. Pietropolli - One of the best experts on this subject based on the ideXlab platform.
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Uterine Myomectomy: Role of gasless laparoscopy in comparison with other minimally invasive approaches
Minimally Invasive Therapy & Allied Technologies, 2012Co-Authors: Francesco Sesti, F. Sesti, A. Pietropolli, Emilio PiccioneAbstract:Abstract Introduction: The aim of this review was to assess the role of gasless laparoscopy (GLM) in comparison with two other minimally invasive approaches to Myomectomy, CO2 laparoscopy (LM) and minilaparotomy (MM), focusing on the most recent randomized or prospective controlled studies. Material and methods: A computerized search was made of the Medline, Science Citation Index, Current Contents, Embase, and PubMed databases for English language publications from the first reports of GLM, LM, and MM in 1995 to 2010. The fifteen most recent randomized or prospective controlled studies were selected and analyzed considering the operative and postoperative parameters. Results: One randomized controlled, one multicenter controlled, three prospective studies about GLM, four randomized controlled studies and one prospective study about LM, four randomized controlled trials and one prospective study about MM were reviewed and analyzed. Discussion: GLM offers some advantages eliminating the adverse effects and...
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Isobaric gasless laparoscopy versus minilaparotomy in Uterine Myomectomy: a randomized trial
Surgical Endoscopy, 2008Co-Authors: F. Sesti, F. Capobianco, T. Capozzolo, A. Pietropolli, E. PiccioneAbstract:Background Isobaric gasless laparoscopy and minilaparotomy have been used as more recent minimally invasive approaches to Myomectomy. This randomized trial aimed to compare the surgical and immediate postoperative outcomes for Myomectomy performed by isobaric gasless laparoscopy with those for minilaparotomy. Methods A total of 100 patients with symptomatic Uterine myomas requiring Myomectomy were randomly allocated to the gasless laparoscopy group or the minilaparotomy group. The randomization procedure was based on a computer-generated list. The primary outcome was a comparison of the discharge times between the two procedures. A power calculation verified that more than 26 patients for each group was necessary to detect a difference of more than 24 h in discharge time with an alpha error level of 5% and a beta error of 80%. Continuous outcome variables were analyzed using the Student’s t -test. Discrete variables were analyzed with the chi-square test or Fisher’s exact test. A p value less than 0.05 was considered statistically significant. Results The mean discharge time was longer for minilaparotomy than for gasless laparoscopy (98.4 ± 1.4 vs 52.8 ± 1.6 h; p
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isobaric gasless laparoscopy versus minilaparotomy in Uterine Myomectomy a randomized trial
Surgical Endoscopy and Other Interventional Techniques, 2008Co-Authors: F. Sesti, F. Capobianco, T. Capozzolo, A. Pietropolli, Emilio PiccioneAbstract:Background Isobaric gasless laparoscopy and minilaparotomy have been used as more recent minimally invasive approaches to Myomectomy. This randomized trial aimed to compare the surgical and immediate postoperative outcomes for Myomectomy performed by isobaric gasless laparoscopy with those for minilaparotomy.
