The Experts below are selected from a list of 3921 Experts worldwide ranked by ideXlab platform
Hui Zhang - One of the best experts on this subject based on the ideXlab platform.
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clinical factors affecting the diagnostic accuracy of assessing dilation and curettage vs frozen section specimens for histologic grade and depth of myometrial invasion in endometrial carcinoma
American Journal of Obstetrics and Gynecology, 2009Co-Authors: Xipeng Wang, Hui ZhangAbstract:Objective We sought to investigate clinical factors affecting accuracy of dilation and curettage (D&C) and frozen section diagnosis of endometrial cancer. Study Design Clinical parameters affecting concordance of D&C or frozen section compared with final hysterectomy pathology were analyzed in 218 patients with endometrial cancer. Results The overall concordance of grade between D&C and final hysterectomy findings was 35.2% (62/176). The following factors increased accuracy of D&C: depth of Uterus Cavity ≥ 9 cm ( P = .043), deep (> 50%) myometrial invasion ( P = .03), P53 positivity ( P = .023), grade 2 ( P = .01), and grade 3 ( P = .048). When comparing frozen section with final hysterectomy findings, the concordance was 69% (58/84) in tumor grade and 87% (67/77) in myometrial invasion. Postmenopausal bleeding ( P = .004) and less resistance index of endometrial lesion blood flow ( P = .005) increased efficacy of grade diagnosis by frozen section. Conclusion Discordance with hysterectomy assessment was most common for women with D&C or frozen section diagnoses of low-grade superficial cancers.
Lema Tavli - One of the best experts on this subject based on the ideXlab platform.
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cotyledonoid dissecting leiomyoma of the Uterus with intravascular growth in postmenopausal woman a case presentation
International Journal of Clinical Oncology, 2011Co-Authors: Kazim Gezginc, Fatma Yazici, Refika Selimoglu, Lema TavliAbstract:Cotyledonoid dissecting leiomyoma (“Sternberg tumor”) is an unusual type of a benign uterine smooth-muscle tumor with a distinctive gross appearance. A 57-year-old woman (gravida 7, para 6), in menopause for 3 years, presented with a 3–4-year history of increased pelvic pain. The transvaginal ultrasound scan showed a 2.5 cm sized heterogenic mass in the Uterus Cavity and 4 × 5 cm sized irregular contoured mass in the right lateral aspect of the Uterus. Total abdominal hysterectomy and bilateral salpingo-oophorectomy were performed with removal of the pelvic tumor extension. Definite pathologic examination result was cotyledonoid dissecting leiomyoma of the Uterus with intravascular growth. The patient is receiving follow-up care every 6 months, and she has no evidence of disease after 22 months of follow-up. The worrying appearance of the gross specimen is often mistaken for malignant or non-uterine lesions that may result in overtreatment. It is important to be aware of this entity to prevent overly aggressive treatment for this benign smooth-muscle neoplasm.
Xipeng Wang - One of the best experts on this subject based on the ideXlab platform.
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clinical factors affecting the diagnostic accuracy of assessing dilation and curettage vs frozen section specimens for histologic grade and depth of myometrial invasion in endometrial carcinoma
American Journal of Obstetrics and Gynecology, 2009Co-Authors: Xipeng Wang, Hui ZhangAbstract:Objective We sought to investigate clinical factors affecting accuracy of dilation and curettage (D&C) and frozen section diagnosis of endometrial cancer. Study Design Clinical parameters affecting concordance of D&C or frozen section compared with final hysterectomy pathology were analyzed in 218 patients with endometrial cancer. Results The overall concordance of grade between D&C and final hysterectomy findings was 35.2% (62/176). The following factors increased accuracy of D&C: depth of Uterus Cavity ≥ 9 cm ( P = .043), deep (> 50%) myometrial invasion ( P = .03), P53 positivity ( P = .023), grade 2 ( P = .01), and grade 3 ( P = .048). When comparing frozen section with final hysterectomy findings, the concordance was 69% (58/84) in tumor grade and 87% (67/77) in myometrial invasion. Postmenopausal bleeding ( P = .004) and less resistance index of endometrial lesion blood flow ( P = .005) increased efficacy of grade diagnosis by frozen section. Conclusion Discordance with hysterectomy assessment was most common for women with D&C or frozen section diagnoses of low-grade superficial cancers.
Kazim Gezginc - One of the best experts on this subject based on the ideXlab platform.
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cotyledonoid dissecting leiomyoma of the Uterus with intravascular growth in postmenopausal woman a case presentation
International Journal of Clinical Oncology, 2011Co-Authors: Kazim Gezginc, Fatma Yazici, Refika Selimoglu, Lema TavliAbstract:Cotyledonoid dissecting leiomyoma (“Sternberg tumor”) is an unusual type of a benign uterine smooth-muscle tumor with a distinctive gross appearance. A 57-year-old woman (gravida 7, para 6), in menopause for 3 years, presented with a 3–4-year history of increased pelvic pain. The transvaginal ultrasound scan showed a 2.5 cm sized heterogenic mass in the Uterus Cavity and 4 × 5 cm sized irregular contoured mass in the right lateral aspect of the Uterus. Total abdominal hysterectomy and bilateral salpingo-oophorectomy were performed with removal of the pelvic tumor extension. Definite pathologic examination result was cotyledonoid dissecting leiomyoma of the Uterus with intravascular growth. The patient is receiving follow-up care every 6 months, and she has no evidence of disease after 22 months of follow-up. The worrying appearance of the gross specimen is often mistaken for malignant or non-uterine lesions that may result in overtreatment. It is important to be aware of this entity to prevent overly aggressive treatment for this benign smooth-muscle neoplasm.
Zhang Di-rong - One of the best experts on this subject based on the ideXlab platform.
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Clinical value of transvaginal three-dimensional ultrasonography in Uterus tumor and malformation
Journal of China Clinic Medical Imaging, 2007Co-Authors: Zhang Di-rongAbstract:Objective: To study the clinical value of transvaginal three-dimensional ultrasonography in uterine diseases. Methods: Fifteen cases of normal Uterus, 25 cases of myoma of Uterus, 7 cases of carcinoma of endometium, 4 cases of hydatidiform mole and 23 cases of malformation of Uterus were detected by three-dimensional ultrasound. Results: With three-dimensional ultrasound, the relation between uterine tumor and Uterus Cavity or Uterus wall, the shape and extent of Uterus Cavity diseases, the shape of endometium of uterine malformation were accurately assesed. Three-dimensional flow imaging can show the structure of vessels in space. Conclusion: Transvaginal three-dimensional ultrasound can help diagnosing Uterus diseases and make up the insufficiency of two dimensional ultrasound.
