The Experts below are selected from a list of 3 Experts worldwide ranked by ideXlab platform
Erwich J.j.h.m. - One of the best experts on this subject based on the ideXlab platform.
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Angiogenic growth factors and their Receptors in first-trimester human decidua of pregnancies further complicated by preeclampsia or fetal growth restriction
2008Co-Authors: Plaisier M., Streefland E., Koolwijk P., Hinsbergh, V.w.m. Van, Helmerhorst F.m., Erwich J.j.h.m.Abstract:Disturbances in decidual and placental vascular development may play a role in the pathogenesis of pregnancy complications. This study focused on the role of angiogenic factors in the first trimester in the pathogenesis of preeclampsia (PE) and/or fetal growth restriction (FGR). First-trimester decidua was obtained during chorionic villous sampling.The expression of the angiogenic factors was determined by reverse transcriptase polymerase chain reaction and related to the pregnancy outcome. First-trimester decidua expressed all angiogenic factors.The differential expression of angiogenic factors appeared to be more prominent in FGR than in PE. These first-trimester samples provided a unique opportunity to obtain information regarding the onset of PE and FGR. First-trimester changes in angiogenic factor expression may well occur as a compensatory mechanism. This, in turn, may unintentionally set the stage for increased angiogenesis and altered decidual/placental vascular adaptation, which may be part of the pathogenesis of PE and/or FGR. © 2008 by the Society for Gynecologic Investigation. Chemicals / CAS: angiopoietin, 250740-90-0; Vasculotropin Receptor, 301253-48-5; Vasculotropin, 127464-60-
Plaisier M. - One of the best experts on this subject based on the ideXlab platform.
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Angiogenic growth factors and their Receptors in first-trimester human decidua of pregnancies further complicated by preeclampsia or fetal growth restriction
2008Co-Authors: Plaisier M., Streefland E., Koolwijk P., Hinsbergh, V.w.m. Van, Helmerhorst F.m., Erwich J.j.h.m.Abstract:Disturbances in decidual and placental vascular development may play a role in the pathogenesis of pregnancy complications. This study focused on the role of angiogenic factors in the first trimester in the pathogenesis of preeclampsia (PE) and/or fetal growth restriction (FGR). First-trimester decidua was obtained during chorionic villous sampling.The expression of the angiogenic factors was determined by reverse transcriptase polymerase chain reaction and related to the pregnancy outcome. First-trimester decidua expressed all angiogenic factors.The differential expression of angiogenic factors appeared to be more prominent in FGR than in PE. These first-trimester samples provided a unique opportunity to obtain information regarding the onset of PE and FGR. First-trimester changes in angiogenic factor expression may well occur as a compensatory mechanism. This, in turn, may unintentionally set the stage for increased angiogenesis and altered decidual/placental vascular adaptation, which may be part of the pathogenesis of PE and/or FGR. © 2008 by the Society for Gynecologic Investigation. Chemicals / CAS: angiopoietin, 250740-90-0; Vasculotropin Receptor, 301253-48-5; Vasculotropin, 127464-60-
Streefland E. - One of the best experts on this subject based on the ideXlab platform.
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Angiogenic growth factors and their Receptors in first-trimester human decidua of pregnancies further complicated by preeclampsia or fetal growth restriction
2008Co-Authors: Plaisier M., Streefland E., Koolwijk P., Hinsbergh, V.w.m. Van, Helmerhorst F.m., Erwich J.j.h.m.Abstract:Disturbances in decidual and placental vascular development may play a role in the pathogenesis of pregnancy complications. This study focused on the role of angiogenic factors in the first trimester in the pathogenesis of preeclampsia (PE) and/or fetal growth restriction (FGR). First-trimester decidua was obtained during chorionic villous sampling.The expression of the angiogenic factors was determined by reverse transcriptase polymerase chain reaction and related to the pregnancy outcome. First-trimester decidua expressed all angiogenic factors.The differential expression of angiogenic factors appeared to be more prominent in FGR than in PE. These first-trimester samples provided a unique opportunity to obtain information regarding the onset of PE and FGR. First-trimester changes in angiogenic factor expression may well occur as a compensatory mechanism. This, in turn, may unintentionally set the stage for increased angiogenesis and altered decidual/placental vascular adaptation, which may be part of the pathogenesis of PE and/or FGR. © 2008 by the Society for Gynecologic Investigation. Chemicals / CAS: angiopoietin, 250740-90-0; Vasculotropin Receptor, 301253-48-5; Vasculotropin, 127464-60-
Koolwijk P. - One of the best experts on this subject based on the ideXlab platform.
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Angiogenic growth factors and their Receptors in first-trimester human decidua of pregnancies further complicated by preeclampsia or fetal growth restriction
2008Co-Authors: Plaisier M., Streefland E., Koolwijk P., Hinsbergh, V.w.m. Van, Helmerhorst F.m., Erwich J.j.h.m.Abstract:Disturbances in decidual and placental vascular development may play a role in the pathogenesis of pregnancy complications. This study focused on the role of angiogenic factors in the first trimester in the pathogenesis of preeclampsia (PE) and/or fetal growth restriction (FGR). First-trimester decidua was obtained during chorionic villous sampling.The expression of the angiogenic factors was determined by reverse transcriptase polymerase chain reaction and related to the pregnancy outcome. First-trimester decidua expressed all angiogenic factors.The differential expression of angiogenic factors appeared to be more prominent in FGR than in PE. These first-trimester samples provided a unique opportunity to obtain information regarding the onset of PE and FGR. First-trimester changes in angiogenic factor expression may well occur as a compensatory mechanism. This, in turn, may unintentionally set the stage for increased angiogenesis and altered decidual/placental vascular adaptation, which may be part of the pathogenesis of PE and/or FGR. © 2008 by the Society for Gynecologic Investigation. Chemicals / CAS: angiopoietin, 250740-90-0; Vasculotropin Receptor, 301253-48-5; Vasculotropin, 127464-60-
Hinsbergh, V.w.m. Van - One of the best experts on this subject based on the ideXlab platform.
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Angiogenic growth factors and their Receptors in first-trimester human decidua of pregnancies further complicated by preeclampsia or fetal growth restriction
2008Co-Authors: Plaisier M., Streefland E., Koolwijk P., Hinsbergh, V.w.m. Van, Helmerhorst F.m., Erwich J.j.h.m.Abstract:Disturbances in decidual and placental vascular development may play a role in the pathogenesis of pregnancy complications. This study focused on the role of angiogenic factors in the first trimester in the pathogenesis of preeclampsia (PE) and/or fetal growth restriction (FGR). First-trimester decidua was obtained during chorionic villous sampling.The expression of the angiogenic factors was determined by reverse transcriptase polymerase chain reaction and related to the pregnancy outcome. First-trimester decidua expressed all angiogenic factors.The differential expression of angiogenic factors appeared to be more prominent in FGR than in PE. These first-trimester samples provided a unique opportunity to obtain information regarding the onset of PE and FGR. First-trimester changes in angiogenic factor expression may well occur as a compensatory mechanism. This, in turn, may unintentionally set the stage for increased angiogenesis and altered decidual/placental vascular adaptation, which may be part of the pathogenesis of PE and/or FGR. © 2008 by the Society for Gynecologic Investigation. Chemicals / CAS: angiopoietin, 250740-90-0; Vasculotropin Receptor, 301253-48-5; Vasculotropin, 127464-60-