The Experts below are selected from a list of 75 Experts worldwide ranked by ideXlab platform
Matthias Pollmeier - One of the best experts on this subject based on the ideXlab platform.
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comparison of the effects of firocoxib carprofen and Vedaprofen in a sodium urate crystal induced synovitis model of arthritis in dogs
Research in Veterinary Science, 2008Co-Authors: H A W Hazewinkel, Walter E Van Den Brom, L F H Theyse, Matthias PollmeierAbstract:A randomized, placebo-controlled, four-period cross-over laboratory study involving eight dogs was conducted to confirm the effective analgesic dose of firocoxib, a selective COX-2 inhibitor, in a synovitis model of arthritis. Firocoxib was compared to Vedaprofen and carprofen, and the effect, defined as a change in weight bearing measured via peak ground reaction, was evaluated at treatment dose levels. A lameness score on a five point scale was also assigned to the affected limb. Peak vertical ground reaction force was considered to be the most relevant measurement in this study. The firocoxib treatment group performed significantly better than placebo at the 3 h post-treatment time point and significantly better than placebo and carprofen at the 7 h post-treatment time point. Improvement in lameness score was also significantly better in the dogs treated with firocoxib than placebo and carprofen at both the 3 and 7 h post-treatment time points.
H A W Hazewinkel - One of the best experts on this subject based on the ideXlab platform.
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comparison of the effects of firocoxib carprofen and Vedaprofen in a sodium urate crystal induced synovitis model of arthritis in dogs
Research in Veterinary Science, 2008Co-Authors: H A W Hazewinkel, Walter E Van Den Brom, L F H Theyse, Matthias PollmeierAbstract:A randomized, placebo-controlled, four-period cross-over laboratory study involving eight dogs was conducted to confirm the effective analgesic dose of firocoxib, a selective COX-2 inhibitor, in a synovitis model of arthritis. Firocoxib was compared to Vedaprofen and carprofen, and the effect, defined as a change in weight bearing measured via peak ground reaction, was evaluated at treatment dose levels. A lameness score on a five point scale was also assigned to the affected limb. Peak vertical ground reaction force was considered to be the most relevant measurement in this study. The firocoxib treatment group performed significantly better than placebo at the 3 h post-treatment time point and significantly better than placebo and carprofen at the 7 h post-treatment time point. Improvement in lameness score was also significantly better in the dogs treated with firocoxib than placebo and carprofen at both the 3 and 7 h post-treatment time points.
Selmi, André Luis - One of the best experts on this subject based on the ideXlab platform.
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A comparison of the analgesic efficacy of Vedaprofeno, carprofen or ketofen after ovariohysterectomy in bitches
Universidade Federal de Santa Maria, 2009Co-Authors: Selmi, André Luis, Lins, Bruno Testoni, Cesar, Fernanda Bicudo, Figueiredo, Juliana Peboni, Duque,juan CarlosAbstract:In this study the authors aimed to compare the efficiency of carprofen, ketoprofen and Vedaprofen for alleviating postoperative pain in bitches submitted to ovariohysterectomy (OH). Pre- and postoperative assessment of pain was made using serum levels of cortisol and glucose, the visual analogue scale (VAS) and the University of Melbourne pain scale (UMPS) in twenty-one bitches undergoing OH. Dogs were randomly assigned to one of three groups: Vedaprofen at 0.5mg kg-1, carprofen at 2.2mg kg-1 or ketoprofen at 2.2mg kg-1. All analgesics were given orally 2 hour before surgery. Assessments were made before surgery and at 1, 2, 3, 4, 5, 6, 7, 8, 12 and 24 hours post-extubation. No dog of this study required additional doses of analgesics. There were no significant differences on serum cortisol and glucose concentrations among groups or from basal values, excepted one hour after extubation. No significant differences on pain scores were observed. It was concluded that Vedaprofen provided as good a level of postoperative analgesia as carprofen and ketoprofen
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Comparação da eficácia analgésica do Vedaprofeno, do carprofeno ou do cetoprofeno após ovariohisterectomia em cadelas
'FapUNIFESP (SciELO)', 2009Co-Authors: Selmi, André Luis, Lins, Bruno Testoni, Cesar, Fernanda Bicudo, Figueiredo, Juliana Peboni, Moreno, Juan Carlos DuqueAbstract:Submitted by Franciele Moreira (francielemoreyra@gmail.com) on 2017-11-27T17:38:49Z No. of bitstreams: 2 Artigo - André Luis Selmi - 2008.pdf: 55409 bytes, checksum: a61b588fca8e765395e9f85eecfb1c1d (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)Rejected by Luciana Ferreira (lucgeral@gmail.com), reason: A data na citação e no nome do arquivo está errada. on 2017-11-29T11:05:26Z (GMT)Submitted by Franciele Moreira (francielemoreyra@gmail.com) on 2017-11-29T11:54:53Z No. of bitstreams: 2 Artigo - André Luis Selmi - 2009.pdf: 55409 bytes, checksum: a61b588fca8e765395e9f85eecfb1c1d (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)Approved for entry into archive by Luciana Ferreira (lucgeral@gmail.com) on 2017-11-29T14:23:20Z (GMT) No. of bitstreams: 2 Artigo - André Luis Selmi - 2009.pdf: 55409 bytes, checksum: a61b588fca8e765395e9f85eecfb1c1d (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)Made available in DSpace on 2017-11-29T14:23:20Z (GMT). No. of bitstreams: 2 Artigo - André Luis Selmi - 2009.pdf: 55409 bytes, checksum: a61b588fca8e765395e9f85eecfb1c1d (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Previous issue date: 2009-06In this study the authors aimed to compare the efficiency of carprofen, ketoprofen and Vedaprofen for alleviating postoperative pain in bitches submitted to ovariohysterectomy (OH). Pre- and postoperative assessment of pain was made using serum levels of cortisol and glucose, the visual analogue scale (VAS) and the University of Melbourne pain scale (UMPS) in twenty-one bitches undergoing OH. Dogs were randomly assigned to one of three groups: Vedaprofen at 0.5mg kg-1, carprofen at 2.2mg kg-1 or ketoprofen at 2.2mg kg-1. All analgesics were given orally 2 hour before surgery. Assessments were made before surgery and at 1, 2, 3, 4, 5, 6, 7, 8, 12 and 24 hours post-extubation. No dog of this study required additional doses of analgesics. There were no significant differences on serum cortisol and glucose concentrations among groups or from basal values, excepted one hour after extubation. No significant differences on pain scores were observed. It was concluded that Vedaprofen provided as good a level of postoperative analgesia as carprofen and ketoprofen.Objetivo deste estudo foi comparar a eficiência do carprofeno, do cetoprofeno e do Vedaprofeno no alívio da dor pós-operatória em cadelas submetidas à ovariohisterectomia (OH) eletiva. Para tal, foram realizadas avaliações pré e pós-operatórias de cortisol e glicose séricos e foram usadas a escala análoga visual (VAS) e a escala da Universidade de Melbourne (University of Melbourne Pain Scale – UMPS). Vinte e uma cadelas foram distribuídas aleatoriamente em três grupos de sete animais cada: Vedaprofeno 0,5mg kg-1, carprofeno 2,2mg kg-1 ou cetoprofeno 2,2mg kg-1. Todos os analgésicos foram administrados pela via oral, duas horas antes da cirurgia. As avaliações foram realizadas antes da cirurgia e uma, duas, três, quatro, cinco, seis, sete, oito, 12 e 24 horas após a extubação. Nenhum dos cães precisou de analgesia de resgate. Com exceção dos valores observados uma hora após a extubação, não houve diferenças significativas nas concentrações séricas de cortisol e glicose entre grupos ou quando foram comparadas aos valores basais. Tampouco houve diferenças significativas nos escores de dor entre as escalas usadas, nos tempos de avaliação para cada grupo, nem entre os grupos. Concluiu-se que o Vedaprofeno fornece analgesia pós-operatória de qualidade similar à obtida com carprofeno e com cetoprofeno
Juan Carlos Duque - One of the best experts on this subject based on the ideXlab platform.
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A comparison of the analgesic efficacy of Vedaprofeno, carprofen or ketofen after ovariohysterectomy in bitches Comparação da eficácia analgésica do Vedaprofeno, do carprofeno ou do cetoprofeno após ovariohisterectomia em cadelas
Universidade Federal de Santa Maria, 2009Co-Authors: André Luis Selmi, Bruno Testoni Lins, Fernanda Bicudo Cesar, Juliana Peboni Figueiredo, Juan Carlos DuqueAbstract:In this study the authors aimed to compare the efficiency of carprofen, ketoprofen and Vedaprofen for alleviating postoperative pain in bitches submitted to ovariohysterectomy (OH). Pre- and postoperative assessment of pain was made using serum levels of cortisol and glucose, the visual analogue scale (VAS) and the University of Melbourne pain scale (UMPS) in twenty-one bitches undergoing OH. Dogs were randomly assigned to one of three groups: Vedaprofen at 0.5mg kg-1, carprofen at 2.2mg kg-1 or ketoprofen at 2.2mg kg-1. All analgesics were given orally 2 hour before surgery. Assessments were made before surgery and at 1, 2, 3, 4, 5, 6, 7, 8, 12 and 24 hours post-extubation. No dog of this study required additional doses of analgesics. There were no significant differences on serum cortisol and glucose concentrations among groups or from basal values, excepted one hour after extubation. No significant differences on pain scores were observed. It was concluded that Vedaprofen provided as good a level of postoperative analgesia as carprofen and ketoprofen.O objetivo deste estudo foi comparar a eficiência do carprofeno, do cetoprofeno e do Vedaprofeno no alívio da dor pós-operatória em cadelas submetidas à ovariohisterectomia (OH) eletiva. Para tal, foram realizadas avaliações pré e pós-operatórias de cortisol e glicose séricos e foram usadas a escala análoga visual (VAS) e a escala da Universidade de Melbourne (University of Melbourne Pain Scale - UMPS). Vinte e uma cadelas foram distribuídas aleatoriamente em três grupos de sete animais cada: Vedaprofeno 0,5mg kg-1, carprofeno 2,2mg kg-1 ou cetoprofeno 2,2mg kg-1. Todos os analgésicos foram administrados pela via oral, duas horas antes da cirurgia. As avaliações foram realizadas antes da cirurgia e uma, duas, três, quatro, cinco, seis, sete, oito, 12 e 24 horas após a extubação. Nenhum dos cães precisou de analgesia de resgate. Com exceção dos valores observados uma hora após a extubação, não houve diferenças significativas nas concentrações séricas de cortisol e glicose entre grupos ou quando foram comparadas aos valores basais. Tampouco houve diferenças significativas nos escores de dor entre as escalas usadas, nos tempos de avaliação para cada grupo, nem entre os grupos. Concluiu-se que o Vedaprofeno fornece analgesia pós-operatória de qualidade similar à obtida com carprofeno e com cetoprofeno
Moreno, Juan Carlos Duque - One of the best experts on this subject based on the ideXlab platform.
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Comparação da eficácia analgésica do Vedaprofeno, do carprofeno ou do cetoprofeno após ovariohisterectomia em cadelas
'FapUNIFESP (SciELO)', 2009Co-Authors: Selmi, André Luis, Lins, Bruno Testoni, Cesar, Fernanda Bicudo, Figueiredo, Juliana Peboni, Moreno, Juan Carlos DuqueAbstract:Submitted by Franciele Moreira (francielemoreyra@gmail.com) on 2017-11-27T17:38:49Z No. of bitstreams: 2 Artigo - André Luis Selmi - 2008.pdf: 55409 bytes, checksum: a61b588fca8e765395e9f85eecfb1c1d (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)Rejected by Luciana Ferreira (lucgeral@gmail.com), reason: A data na citação e no nome do arquivo está errada. on 2017-11-29T11:05:26Z (GMT)Submitted by Franciele Moreira (francielemoreyra@gmail.com) on 2017-11-29T11:54:53Z No. of bitstreams: 2 Artigo - André Luis Selmi - 2009.pdf: 55409 bytes, checksum: a61b588fca8e765395e9f85eecfb1c1d (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)Approved for entry into archive by Luciana Ferreira (lucgeral@gmail.com) on 2017-11-29T14:23:20Z (GMT) No. of bitstreams: 2 Artigo - André Luis Selmi - 2009.pdf: 55409 bytes, checksum: a61b588fca8e765395e9f85eecfb1c1d (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)Made available in DSpace on 2017-11-29T14:23:20Z (GMT). No. of bitstreams: 2 Artigo - André Luis Selmi - 2009.pdf: 55409 bytes, checksum: a61b588fca8e765395e9f85eecfb1c1d (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Previous issue date: 2009-06In this study the authors aimed to compare the efficiency of carprofen, ketoprofen and Vedaprofen for alleviating postoperative pain in bitches submitted to ovariohysterectomy (OH). Pre- and postoperative assessment of pain was made using serum levels of cortisol and glucose, the visual analogue scale (VAS) and the University of Melbourne pain scale (UMPS) in twenty-one bitches undergoing OH. Dogs were randomly assigned to one of three groups: Vedaprofen at 0.5mg kg-1, carprofen at 2.2mg kg-1 or ketoprofen at 2.2mg kg-1. All analgesics were given orally 2 hour before surgery. Assessments were made before surgery and at 1, 2, 3, 4, 5, 6, 7, 8, 12 and 24 hours post-extubation. No dog of this study required additional doses of analgesics. There were no significant differences on serum cortisol and glucose concentrations among groups or from basal values, excepted one hour after extubation. No significant differences on pain scores were observed. It was concluded that Vedaprofen provided as good a level of postoperative analgesia as carprofen and ketoprofen.Objetivo deste estudo foi comparar a eficiência do carprofeno, do cetoprofeno e do Vedaprofeno no alívio da dor pós-operatória em cadelas submetidas à ovariohisterectomia (OH) eletiva. Para tal, foram realizadas avaliações pré e pós-operatórias de cortisol e glicose séricos e foram usadas a escala análoga visual (VAS) e a escala da Universidade de Melbourne (University of Melbourne Pain Scale – UMPS). Vinte e uma cadelas foram distribuídas aleatoriamente em três grupos de sete animais cada: Vedaprofeno 0,5mg kg-1, carprofeno 2,2mg kg-1 ou cetoprofeno 2,2mg kg-1. Todos os analgésicos foram administrados pela via oral, duas horas antes da cirurgia. As avaliações foram realizadas antes da cirurgia e uma, duas, três, quatro, cinco, seis, sete, oito, 12 e 24 horas após a extubação. Nenhum dos cães precisou de analgesia de resgate. Com exceção dos valores observados uma hora após a extubação, não houve diferenças significativas nas concentrações séricas de cortisol e glicose entre grupos ou quando foram comparadas aos valores basais. Tampouco houve diferenças significativas nos escores de dor entre as escalas usadas, nos tempos de avaliação para cada grupo, nem entre os grupos. Concluiu-se que o Vedaprofeno fornece analgesia pós-operatória de qualidade similar à obtida com carprofeno e com cetoprofeno
