The Experts below are selected from a list of 70935 Experts worldwide ranked by ideXlab platform
Joseph H. Levine - One of the best experts on this subject based on the ideXlab platform.
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Double sequential external shocks for refractory Ventricular Fibrillation
Journal of the American College of Cardiology, 1994Co-Authors: David H. Hoch, William P. Batsford, Steven M. Greenberg, Craig M. Mcpherson, Lynda E. Rosenfeld, Mark Marieb, Joseph H. LevineAbstract:Abstract Objectives. A technique for terminating refractory Ventricular Fibrillation is described. Background. Refractory Ventricular Fibrillation can occur in up to 0.1% of electrophysiologic studies. Animal studies have shown that rapid sequential shocks may reduce Ventricular Fibrillation threshold. Methods. Five patients of 2,990 consecutive patients in a 3-year period experienced refractory Ventricular Fibrillation during 5,450 routine electrophysiologic studies. Multiple shocks were delivered by means of a single defibrillator. Double sequential shocks were delivered externally 0.5 to 4.5 s apart by means of two defibrillators with separate pairs of electrodes. Results. In all patients, standard deFibrillation was unsuccessful, but all were successfully resuscitated using the double sequential shocks. Conclusions. This report stresses the importance of an additional defibrillator being readily available during electrophysiologic testing. This technique of rapid, double sequential external shocks may have general applicability, providing a simple and potentially lifesaving approach to refractory Ventricular Fibrillation.
Michel Haïssaguerre - One of the best experts on this subject based on the ideXlab platform.
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Editorial Radiofrequency Ablation In Ventricular Fibrillation
2008Co-Authors: Jayachandran Thejus, Johnson Francis, Michel HaïssaguerreAbstract:Ventricular Fibrillation, radiofrequency catheter ablation Ventricular Fibrillation (VF) is the most common arrhythmic cause of sudden cardiac death. The present recommendation for prevention of VF is ICD implantation. However, ICDs are costly; the shocks they give are often very uncomfortable for the patient and they may need reimplantation if there is battery depletion. Radiofrequency ablation of VF was pioneered by Haissaguerre
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mapping and ablation of idiopathic Ventricular Fibrillation
Circulation, 2002Co-Authors: Michel Haïssaguerre, Morio Shoda, Thomas Arentz, Dietrich Kalushe, Dipen C. Shah, Josef Kautzner, Pierre Jais, Akihiko Nogami, Dominique Lamaison, Michael GriffithAbstract:Background— Ventricular Fibrillation is the main mechanism of sudden cardiac death. The feasibility of eliminating recurrent episodes by catheter ablation has not been reported. Methods and Results— Twenty-seven patients without known heart disease (13 men, 14 women, 41±14 years of age) were studied after being resuscitated from recurrent (10±12) episodes of primary idiopathic Ventricular Fibrillation; 23 had received a defibrillator. The first initiating beat of Ventricular Fibrillation had an identical electrocardiographic morphology and coupling interval (297±41 ms) to preceding isolated premature beats typically noted in the aftermath of resuscitation. These triggers were localized by mapping the earliest electrical activity and ablated by local radiofrequency delivery. Outcome was assessed by Holter and defibrillator memory interrogation. Premature beats were elicited from the Purkinje conducting system in 23 patients: from the left Ventricular septum in 10, from the anterior right ventricle in 9, an...
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Role of Purkinje conducting system in triggering of idiopathic Ventricular Fibrillation
The Lancet, 2002Co-Authors: Michel Haïssaguerre, Morio Shoda, Thomas Arentz, Dietrich Kalushe, Dipen C. Shah, Josef Kautzner, Pierre Jais, Michael J. Griffith, Alan H. Kadish, Fiorenzo GaitaAbstract:Ventricular Fibrillation is the main mechanism of sudden cardiac death, but the source of its spontaneous initiation has not been mapped. 16 patients were investigated by electrography and radiofrequency ablation after resuscitation from recurrent idiopathic Ventricular Fibrillation. Triggers of Ventricular Fibrillation originated from various locations within the Purkinje system in 12 patients and from the ordinary myocardial muscle in four. The accuracy of mapping was confirmed by acute elimination of triggers by radiofrequency delivery, and there was no recurrence of Ventricular Fibrillation in 14 patients. Long-term follow-up is necessary to establish that ablation is curative and avoids use of a defibrillator.
David H. Hoch - One of the best experts on this subject based on the ideXlab platform.
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Double sequential external shocks for refractory Ventricular Fibrillation
Journal of the American College of Cardiology, 1994Co-Authors: David H. Hoch, William P. Batsford, Steven M. Greenberg, Craig M. Mcpherson, Lynda E. Rosenfeld, Mark Marieb, Joseph H. LevineAbstract:Abstract Objectives. A technique for terminating refractory Ventricular Fibrillation is described. Background. Refractory Ventricular Fibrillation can occur in up to 0.1% of electrophysiologic studies. Animal studies have shown that rapid sequential shocks may reduce Ventricular Fibrillation threshold. Methods. Five patients of 2,990 consecutive patients in a 3-year period experienced refractory Ventricular Fibrillation during 5,450 routine electrophysiologic studies. Multiple shocks were delivered by means of a single defibrillator. Double sequential shocks were delivered externally 0.5 to 4.5 s apart by means of two defibrillators with separate pairs of electrodes. Results. In all patients, standard deFibrillation was unsuccessful, but all were successfully resuscitated using the double sequential shocks. Conclusions. This report stresses the importance of an additional defibrillator being readily available during electrophysiologic testing. This technique of rapid, double sequential external shocks may have general applicability, providing a simple and potentially lifesaving approach to refractory Ventricular Fibrillation.
Michiel J Janse - One of the best experts on this subject based on the ideXlab platform.
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Vulnerability to Ventricular Fibrillation.
Chaos, 1998Co-Authors: Michiel J JanseAbstract:One of the factors that favors the development of Ventricular Fibrillation is an increase in the dispersion of refractoriness. Experiments will be described in which an increase in dispersion in the recovery of excitability was determined during brief episodes of enhanced sympathetic nerve activity, known to increase the risk of Fibrillation. Whereas in the normal heart Ventricular Fibrillation can be induced by a strong electrical shock, a premature stimulus of moderate intensity only induces Fibrillation in the presence of regional ischemia, which greatly increases the dispersion of refractoriness. One factor that is of importance for the transition of reentrant Ventricular tachycardia to Ventricular Fibrillation during acute regional ischemia is the subendocardial Purkinje system. After selective destruction of the Purkinje network by lugol, reentrant tachycardias still develop in the ischemic region, but they do not degenerate into Fibrillation. Finally, attempts were made to determine the minimal mas...
Erin L Simon - One of the best experts on this subject based on the ideXlab platform.
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refractory Ventricular Fibrillation in patient taking lamictal
American Journal of Emergency Medicine, 2018Co-Authors: Andrew Dream, Helena Holmgren, Rebecca Merrill, Erin L SimonAbstract:Abstract Refractory Ventricular Fibrillation occurs when there are three or more episodes of Ventricular Fibrillation within a 24-hour period. We report the first case of a 35-year-old woman without prior medical or family cardiac history who sustained refractory Ventricular Fibrillation while taking Lamictal for bipolar depression. She presented to the Emergency Department (ED) after a syncopal episode at work. She then sustained a cardiac arrest and required deFibrillation in the ED multiple times due to recurrent Ventricular Fibrillation. The patient received a Subcutaneous Implantable Cardio-Defibrillator and was discharged home. There was no identifiable cardiac or medical cause of her Ventricular Fibrillation and the electrophysiologist suspected Lamictal caused her refractory Ventricular Fibrillation.
