The Experts below are selected from a list of 1536 Experts worldwide ranked by ideXlab platform

Akira Ishiyama - One of the best experts on this subject based on the ideXlab platform.

  • temporal bone Verrucous Carcinoma outcomes and treatment controversy
    European Archives of Oto-rhino-laryngology, 2010
    Co-Authors: Mia E Miller, Neil A Martin, Guy Juillard, Sunita Bhuta, Akira Ishiyama
    Abstract:

    Verrucous Carcinoma is a rare tumor that presents in the head and neck with the most common sites being the oral cavity and larynx. Fourteen cases of Verrucous Carcinoma of the temporal bone have been described in literature; this study aims to examine treatment outcomes and discuss the controversy surrounding postoperative radiation. The study design included a literature review along with individual case report in the setting of a tertiary care medical center. Outcome analysis of all cases of Verrucous Carcinoma of the temporal bone, which are documented in the English literature, and presentation of a single patient report including gross, histologic and radiologic analyses were performed. The longest recorded survival for Verrucous Carcinoma of the temporal bone occurs in patients treated with surgery alone. Poorer outcomes for patients treated with adjuvant (chemo)radiation may be due to more advanced stage of disease at the time of treatment. Early reports of radiation leading to tumor dedifferentiation or early recurrence are not supported by more recent studies. Whether adjuvant radiation therapy is indicated in Verrucous Carcinoma of the temporal bone remains controversial.

  • temporal bone Verrucous Carcinoma outcomes and treatment controversy
    Laryngoscope, 2010
    Co-Authors: Mia E Miller, Neil A Martin, Guy Juillard, Sunita Bhuta, Akira Ishiyama
    Abstract:

    OBJECTIVES: Verrucous Carcinoma is a rare tumor that presents in the head and neck with the most common sites in the larynx and oral cavity. Fourteen cases of Verrucous Carcinoma of the temporal bone have been described in the literature; this study aims to examine treatment outcomes and discuss the controversy surrounding postoperative radiation. STUDY DESIGN: A literature review along with individual case report in the setting of a tertiary care medical center. METHODS: Outcomes analysis of all cases of Verrucous Carcinoma of the temporal bone which are documented in the English literature; presentation of a single patient report including gross, histologic, and radiologic analyses. RESULTS: The longest recorded survival for Verrucous Carcinoma of the temporal bone occurs in patients treated with surgery alone. Poorer outcomes for patients treated with adjuvant (chemo)radiation may be due to more advanced stage disease at the time of treatment. Early reports of radiation leading to tumor dedifferentiation or early recurrence are not supported by more recent studies. Whether adjuvant radiation therapy is indicated in Verrucous Carcinoma of the temporal bone remains a controversial.

Afaf Amarti - One of the best experts on this subject based on the ideXlab platform.

  • Verrucous Carcinoma arising in an extended giant condyloma acuminatum buschke lowenstein tumor a case report and review of the literature
    Journal of Medical Case Reports, 2013
    Co-Authors: Mustapha Ahsaini, Yasser Tahiri, Mohammed Fadl Tazi, Jallaledine Elammari, Soufiane Mellas, Abdelhak Khallouk, Mohammed Jamal El Fassi, My Hassan Farih, Hind Elfatmi, Afaf Amarti
    Abstract:

    Verrucous Carcinoma of the external genitalia and perianal region is a rare variant of well-differentiated squamous cell Carcinoma. It has been reported to have limited metastatic potential. We report the case of a 54 year-old Moroccan man who presented with locally advanced giant condyloma acuminatum (Buschke–Lowenstein tumor) after prolonged intervals of neglect (approximately 10 years). The disease covered his suprapubic, external genitalia and perianal region. It was locally aggressive with extensive tissue destruction. After a biopsy of the lesion, the diagnosis of Verrucous Carcinoma was confirmed. He initially received chemoradiotherapy, followed by extensive local excision, but he developed septic shock and died a few days later. The purpose of this case report is to present a case of Verrucous Carcinoma arising in an extensive giant condyloma acuminatum (Buschke–Lowenstein tumor) and discuss the literature on its diagnosis and management.

  • Verrucous Carcinoma arising in an extended giant condyloma acuminatum buschke lowenstein tumor a case report and review of the literature
    Journal of Medical Case Reports, 2013
    Co-Authors: Mustapha Ahsaini, Yasser Tahiri, Mohammed Fadl Tazi, Jallaledine Elammari, Soufiane Mellas, Abdelhak Khallouk, Mohammed Jamal El Fassi, My Hassan Farih, Hind Elfatmi, Afaf Amarti
    Abstract:

    Introduction Verrucous Carcinoma of the external genitalia and perianal region is a rare variant of well-differentiated squamous cell Carcinoma. It has been reported to have limited metastatic potential.

Mia E Miller - One of the best experts on this subject based on the ideXlab platform.

  • temporal bone Verrucous Carcinoma outcomes and treatment controversy
    European Archives of Oto-rhino-laryngology, 2010
    Co-Authors: Mia E Miller, Neil A Martin, Guy Juillard, Sunita Bhuta, Akira Ishiyama
    Abstract:

    Verrucous Carcinoma is a rare tumor that presents in the head and neck with the most common sites being the oral cavity and larynx. Fourteen cases of Verrucous Carcinoma of the temporal bone have been described in literature; this study aims to examine treatment outcomes and discuss the controversy surrounding postoperative radiation. The study design included a literature review along with individual case report in the setting of a tertiary care medical center. Outcome analysis of all cases of Verrucous Carcinoma of the temporal bone, which are documented in the English literature, and presentation of a single patient report including gross, histologic and radiologic analyses were performed. The longest recorded survival for Verrucous Carcinoma of the temporal bone occurs in patients treated with surgery alone. Poorer outcomes for patients treated with adjuvant (chemo)radiation may be due to more advanced stage of disease at the time of treatment. Early reports of radiation leading to tumor dedifferentiation or early recurrence are not supported by more recent studies. Whether adjuvant radiation therapy is indicated in Verrucous Carcinoma of the temporal bone remains controversial.

  • temporal bone Verrucous Carcinoma outcomes and treatment controversy
    Laryngoscope, 2010
    Co-Authors: Mia E Miller, Neil A Martin, Guy Juillard, Sunita Bhuta, Akira Ishiyama
    Abstract:

    OBJECTIVES: Verrucous Carcinoma is a rare tumor that presents in the head and neck with the most common sites in the larynx and oral cavity. Fourteen cases of Verrucous Carcinoma of the temporal bone have been described in the literature; this study aims to examine treatment outcomes and discuss the controversy surrounding postoperative radiation. STUDY DESIGN: A literature review along with individual case report in the setting of a tertiary care medical center. METHODS: Outcomes analysis of all cases of Verrucous Carcinoma of the temporal bone which are documented in the English literature; presentation of a single patient report including gross, histologic, and radiologic analyses. RESULTS: The longest recorded survival for Verrucous Carcinoma of the temporal bone occurs in patients treated with surgery alone. Poorer outcomes for patients treated with adjuvant (chemo)radiation may be due to more advanced stage disease at the time of treatment. Early reports of radiation leading to tumor dedifferentiation or early recurrence are not supported by more recent studies. Whether adjuvant radiation therapy is indicated in Verrucous Carcinoma of the temporal bone remains a controversial.

S L Johansson - One of the best experts on this subject based on the ideXlab platform.

  • penile Verrucous Carcinoma a clinicopathologic human papillomavirus typing and flow cytometric analysis
    Modern Pathology, 1992
    Co-Authors: A S Masih, M H Stoler, G M Farrow, T N Wooldridge, S L Johansson
    Abstract:

    The relationship of various verruciform squamous cell proliferations of the penis such as Verrucous Carcinoma, with or without anaplasia and giant condyloma, is uncertain. We conducted clinicopathologic, flow cytometric, and HPV typing studies on 15 cases of penile Verrucous Carcinoma to investigate its place in the spectrum of genital squamous proliferations. The results show a high degree of morphologic uniformity with respect to Ackerman's original diagnostic criteria, as well as to several other histopathologic features evaluated. The latter include polygonal squamous cells with glassy cytoplasm, centrally located vesicular nuclei, intercellular edema, well-formed cellular bridges, and absence or paucity of koilocytes, true fibrovascular cores, and keratohyalin granules. Intraepithelial abscesses and crust-formation were present in many cases. Four cases contained microscopic foci of cellular anaplasia. These hybrid Verrucous-squamous Carcinomas presented and behaved similarly to the pure Verrucous Carcinomas. Tumor recurrence was correlated with extent of initial surgical management. DNA ploidy analysis by flow cytometry performed on eight pure and two hybrid tumors showed uniform diploid populations with similar G1/G2 fractions in both groups. Eight pure and two hybrid tumors evaluated for HPV by isotopic in situ hybridization were uniformly negative for HPV types 6, 11, 16, 18, and 31. The results show that penile Verrucous Carcinoma demonstrates characteristic and uniform morphologic features and does not contain the HPV types typically associated with condyloma acuminatum, giant condyloma of Buschke-Lowenstein, and condylomatous Carcinoma.

Mustapha Ahsaini - One of the best experts on this subject based on the ideXlab platform.

  • Verrucous Carcinoma arising in an extended giant condyloma acuminatum buschke lowenstein tumor a case report and review of the literature
    Journal of Medical Case Reports, 2013
    Co-Authors: Mustapha Ahsaini, Yasser Tahiri, Mohammed Fadl Tazi, Jallaledine Elammari, Soufiane Mellas, Abdelhak Khallouk, Mohammed Jamal El Fassi, My Hassan Farih, Hind Elfatmi, Afaf Amarti
    Abstract:

    Verrucous Carcinoma of the external genitalia and perianal region is a rare variant of well-differentiated squamous cell Carcinoma. It has been reported to have limited metastatic potential. We report the case of a 54 year-old Moroccan man who presented with locally advanced giant condyloma acuminatum (Buschke–Lowenstein tumor) after prolonged intervals of neglect (approximately 10 years). The disease covered his suprapubic, external genitalia and perianal region. It was locally aggressive with extensive tissue destruction. After a biopsy of the lesion, the diagnosis of Verrucous Carcinoma was confirmed. He initially received chemoradiotherapy, followed by extensive local excision, but he developed septic shock and died a few days later. The purpose of this case report is to present a case of Verrucous Carcinoma arising in an extensive giant condyloma acuminatum (Buschke–Lowenstein tumor) and discuss the literature on its diagnosis and management.

  • Verrucous Carcinoma arising in an extended giant condyloma acuminatum buschke lowenstein tumor a case report and review of the literature
    Journal of Medical Case Reports, 2013
    Co-Authors: Mustapha Ahsaini, Yasser Tahiri, Mohammed Fadl Tazi, Jallaledine Elammari, Soufiane Mellas, Abdelhak Khallouk, Mohammed Jamal El Fassi, My Hassan Farih, Hind Elfatmi, Afaf Amarti
    Abstract:

    Introduction Verrucous Carcinoma of the external genitalia and perianal region is a rare variant of well-differentiated squamous cell Carcinoma. It has been reported to have limited metastatic potential.