The Experts below are selected from a list of 4374 Experts worldwide ranked by ideXlab platform
J J Verlaan - One of the best experts on this subject based on the ideXlab platform.
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extensive thoracolumbosacral Vertebral Osteomyelitis after lemierre syndrome
European Spine Journal, 2015Co-Authors: D H R Kempen, M Van Dijk, A I M Hoepelman, F C Oner, J J VerlaanAbstract:Purpose To present a unique case of multilevel Vertebral Osteomyelitis after Lemierre syndrome.
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Extensive thoracolumbosacral Vertebral Osteomyelitis after Lemierre syndrome.
European spine journal : official publication of the European Spine Society the European Spinal Deformity Society and the European Section of the Cerv, 2014Co-Authors: D H R Kempen, M Van Dijk, A I M Hoepelman, F C Oner, J J VerlaanAbstract:To present a unique case of multilevel Vertebral Osteomyelitis after Lemierre syndrome. A previously healthy 27-year-old man presented in the Emergency Department in septic shock because of Lemierre syndrome for which he was subsequently treated with intravenous benzylpenicillin for 2 months. Two and a half months later, the patient was readmitted with severe back pain without neurological deficits or fever. Imaging revealed an extensive Vertebral Osteomyelitis of the complete thoracic, lumbar and sacral spine. Although the blood cultures obtained at the initial admission for Lemierre syndrome revealed Fusobacterium species and Streptococcus milleri, the cultures from the spinal biopsies remained negative. Histology of the spinal biopsies showed a purulent sclerosing Osteomyelitis. The patient was successfully treated with intravenous piperacillin and tazobactam. Despite persisting back pain, no recurrence of infection was seen at 3 years of follow-up. Lemierre syndrome and an extensive thoracolumbosacral Vertebral Osteomyelitis are rare but serious infections. Clinicians must maintain a high index of suspicion for infectious metastases leading to Vertebral Osteomyelitis when a patient presents with back pain after an episode of life-threatening septicaemia caused by Lemierre syndrome.
Bente Danneskiold-samsøe - One of the best experts on this subject based on the ideXlab platform.
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Bacteremia complicated by Vertebral Osteomyelitis due to Streptococcus bovis.
European Journal of Clinical Microbiology & Infectious Diseases, 1999Co-Authors: I. Hechmann Wittrup, M. L. Chenoufi Schaadt, Magnus Arpi, Bente Danneskiold-samsøeAbstract:The diagnosis of Vertebral Osteomyelitis is easily missed, especially in the elderly in whom clinical signs of bacteremia might not be manifest. Spontaneously occurring disc-space infection in adults often has an insidious presentation. The infecting microorganism can be difficult to identify. Although discitis due to Streptococcus bovis is occasionally found, it is often difficult to fully confirm the diagnosis. Here, a case of Vertebral Osteomyelitis due to this microorganism is reported.
D H R Kempen - One of the best experts on this subject based on the ideXlab platform.
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extensive thoracolumbosacral Vertebral Osteomyelitis after lemierre syndrome
European Spine Journal, 2015Co-Authors: D H R Kempen, M Van Dijk, A I M Hoepelman, F C Oner, J J VerlaanAbstract:Purpose To present a unique case of multilevel Vertebral Osteomyelitis after Lemierre syndrome.
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Extensive thoracolumbosacral Vertebral Osteomyelitis after Lemierre syndrome.
European spine journal : official publication of the European Spine Society the European Spinal Deformity Society and the European Section of the Cerv, 2014Co-Authors: D H R Kempen, M Van Dijk, A I M Hoepelman, F C Oner, J J VerlaanAbstract:To present a unique case of multilevel Vertebral Osteomyelitis after Lemierre syndrome. A previously healthy 27-year-old man presented in the Emergency Department in septic shock because of Lemierre syndrome for which he was subsequently treated with intravenous benzylpenicillin for 2 months. Two and a half months later, the patient was readmitted with severe back pain without neurological deficits or fever. Imaging revealed an extensive Vertebral Osteomyelitis of the complete thoracic, lumbar and sacral spine. Although the blood cultures obtained at the initial admission for Lemierre syndrome revealed Fusobacterium species and Streptococcus milleri, the cultures from the spinal biopsies remained negative. Histology of the spinal biopsies showed a purulent sclerosing Osteomyelitis. The patient was successfully treated with intravenous piperacillin and tazobactam. Despite persisting back pain, no recurrence of infection was seen at 3 years of follow-up. Lemierre syndrome and an extensive thoracolumbosacral Vertebral Osteomyelitis are rare but serious infections. Clinicians must maintain a high index of suspicion for infectious metastases leading to Vertebral Osteomyelitis when a patient presents with back pain after an episode of life-threatening septicaemia caused by Lemierre syndrome.
Albert Pahissa - One of the best experts on this subject based on the ideXlab platform.
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Spontaneous pyogenic Vertebral Osteomyelitis and endocarditis: Incidence, risk factors, and outcome
The American journal of medicine, 2005Co-Authors: Carlos Pigrau, Benito Almirante, Xavier Flores, Vicenç Falcó, Dolors Rodríguez, I. Gasser, Carlos Villanueva, Albert PahissaAbstract:Abstract Purpose The relationship between pyogenic Vertebral Osteomyelitis and infectious endocarditis is uncertain. This study investigates the incidence and risk factors of infectious endocarditis in patients with pyogenic Vertebral Osteomyelitis, and the outcome of pyogenic Vertebral Osteomyelitis with and without associated infectious endocarditis. Methods A retrospective record review was conducted of all cases of Vertebral Osteomyelitis from January 1986 to June 2002, occurring in a tertiary referral hospital. Patients were followed for at least 6 months with careful attention to detection of infectious endocarditis and relapses. Results Among 606 patients with infectious endocarditis, 28 (4.6%) had pyogenic Vertebral Osteomyelitis. Among 91 cases of pyogenic Vertebral Osteomyelitis, 28 (30.8%) had infectious endocarditis. In 6 patients with no clinical signs of infectious endocarditis, the disease was established by routine echocardiography. Infectious endocarditis was more common in patients with predisposing heart conditions and streptococcal pyogenic Vertebral Osteomyelitis infection. Overall, pyogenic Vertebral Osteomyelitis in-hospital mortality was 11% (7.1% with infectious endocarditis). Twelve of 25 patients with infectious endocarditis with uncomplicated pyogenic Vertebral Osteomyelitis were treated for 4 to 6 weeks (endocarditis protocol), with no pyogenic Vertebral Osteomyelitis relapses. Conclusions When specifically sought, the incidence of infectious endocarditis is high in patients with pyogenic Vertebral Osteomyelitis. Oral therapy may be an option for uncomplicated pyogenic Vertebral Osteomyelitis; nevertheless, in gram-positive infections, this approach should only be considered after excluding infectious endocarditis. Favorable outcome with shorter treatment in uncomplicated pyogenic Vertebral Osteomyelitis associated with infectious endocarditis suggests that prolonged therapy may not be needed in this subgroup except for those infected by difficult to treat microorganisms, such as methicillin-resistant Staphylococcus aureus or Candida spp.
I. Hechmann Wittrup - One of the best experts on this subject based on the ideXlab platform.
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Bacteremia complicated by Vertebral Osteomyelitis due to Streptococcus bovis.
European Journal of Clinical Microbiology & Infectious Diseases, 1999Co-Authors: I. Hechmann Wittrup, M. L. Chenoufi Schaadt, Magnus Arpi, Bente Danneskiold-samsøeAbstract:The diagnosis of Vertebral Osteomyelitis is easily missed, especially in the elderly in whom clinical signs of bacteremia might not be manifest. Spontaneously occurring disc-space infection in adults often has an insidious presentation. The infecting microorganism can be difficult to identify. Although discitis due to Streptococcus bovis is occasionally found, it is often difficult to fully confirm the diagnosis. Here, a case of Vertebral Osteomyelitis due to this microorganism is reported.
