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Ann M. Burgess - One of the best experts on this subject based on the ideXlab platform.
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the ocular Vestibular evoked myogenic potential to air conducted sound probable superior Vestibular Nerve origin
Clinical Neurophysiology, 2011Co-Authors: Ian S. Curthoys, Munetaka Ushio, Shin-ichi Iwasaki, Yasuhiro Chihara, Leigh A. Mcgarvie, Ann M. BurgessAbstract:Abstract Objective Intense air-conducted sound (ACS) elicits an ocular Vestibular-evoked myogenic potential (oVEMP), and it has been suggested that it does so by stimulating saccular receptors and afferents in the inferior Vestibular Nerve and so activating a crossed sacculo-ocular pathway. Bone conducted vibration (BCV) also elicits an oVEMP probably by activating utricular receptors and a crossed utriculo-ocular pathway. Are there two separate pathways mediating oVEMPs for ACS and BCV? If saccular receptors and afferents are primarily responsible for the oVEMP to ACS, then the oVEMP to ACS should be normal in patients with reduced or absent utricular function – unilateral superior Vestibular neuritis (SVN). If utricular receptors and afferents are primarily responsible for oVEMP n10, then oVEMP to ACS should be reduced or absent in SVN patients, and in these patients there should be a close relationship between the size of the oVEMP n10 to BCV and to ACS. Methods The n10 component of the oVEMP to 500 Hz BCV and to 500 Hz ACS was recorded in 10 patients with unilateral SVN but who had saccular and inferior Vestibular Nerve function preserved, as shown by their normal cVEMP responses to ACS. Results In SVN patients with normal saccular and inferior Vestibular Nerve function, the oVEMP n10 in response to ACS was reduced or absent. Across SVN patients there was a very close correspondence between the size of oVEMP n10 for ACS and for BCV. Conclusions The n10 component of the oVEMP to ACS is probably mediated predominantly by the superior Vestibular Nerve and so most likely by utricular receptors and afferents. Significance The n10 component of the oVEMP to either ACS or BCV probably indicates mainly superior Vestibular Nerve function.
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The ocular Vestibular-evoked myogenic potential to air-conducted sound; probable superior Vestibular Nerve origin
Clinical Neurophysiology, 2011Co-Authors: Ian S. Curthoys, Munetaka Ushio, Shin-ichi Iwasaki, Yasuhiro Chihara, Leigh A. Mcgarvie, Ann M. BurgessAbstract:Objective: Intense air-conducted sound (ACS) elicits an ocular Vestibular-evoked myogenic potential (oVEMP), and it has been suggested that it does so by stimulating saccular receptors and afferents in the inferior Vestibular Nerve and so activating a crossed sacculo-ocular pathway. Bone conducted vibration (BCV) also elicits an oVEMP probably by activating utricular receptors and a crossed utriculo-ocular pathway. Are there two separate pathways mediating oVEMPs for ACS and BCV? If saccular receptors and afferents are primarily responsible for the oVEMP to ACS, then the oVEMP to ACS should be normal in patients with reduced or absent utricular function - unilateral superior Vestibular neuritis (SVN). If utricular receptors and afferents are primarily responsible for oVEMP n10, then oVEMP to ACS should be reduced or absent in SVN patients, and in these patients there should be a close relationship between the size of the oVEMP n10 to BCV and to ACS. Methods: The n10 component of the oVEMP to 500. Hz BCV and to 500. Hz ACS was recorded in 10 patients with unilateral SVN but who had saccular and inferior Vestibular Nerve function preserved, as shown by their normal cVEMP responses to ACS. Results: In SVN patients with normal saccular and inferior Vestibular Nerve function, the oVEMP n10 in response to ACS was reduced or absent. Across SVN patients there was a very close correspondence between the size of oVEMP n10 for ACS and for BCV. Conclusions: The n10 component of the oVEMP to ACS is probably mediated predominantly by the superior Vestibular Nerve and so most likely by utricular receptors and afferents. Significance: The n10 component of the oVEMP to either ACS or BCV probably indicates mainly superior Vestibular Nerve function. © 2010 International Federation of Clinical Neurophysiology.
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the role of the superior Vestibular Nerve in generating ocular Vestibular evoked myogenic potentials to bone conducted vibration at fz
Clinical Neurophysiology, 2009Co-Authors: Shin-ichi Iwasaki, Y. E. Smulders, Ann M. Burgess, Yasuhiro Chihara, Gabor Michael Halmagyi, Ian S. Curthoys, Toshiaki MurofushiAbstract:Objective: The n10 component (n10) of the ocular Vestibular evoked myogenic potential (oVEMP) to brief bone conducted vibration (BCV) of the forehead at Fz is probably caused by the vibration selectively activating Vestibular otolithic receptors. If the n10 is due primarily to utricular activation then diseases which affect only the superior division of the Vestibular Nerve (SVN) should reduce or eliminate n10. Methods: The n10 component of the oVEMP was measured in 13 patients with unilateral SVN but with inferior Vestibular Nerve function preserved. Results: We compared the n10 to BCV of these 13 SVN patients to previously published data for healthy subjects and patients after complete unilateral Vestibular loss. We found that in 12 out of the 13 patients with SVN, n10 was markedly reduced or absent under the contralesional eye. Conclusion: Since all utricular afferents course in the superior Vestibular Nerve and in 12/13 of these patients the n10 was reduced we conclude that the n10 component of the oVEMP to BCV is probably mediated by the superior Vestibular Nerve and probably due to activation of mainly utricular receptors. Significance: The n10 appears to be a simple new test of superior Vestibular Nerve and probably mainly utricular function.
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The role of the superior Vestibular Nerve in generating ocular Vestibular-evoked myogenic potentials to bone conducted vibration at Fz
Clinical Neurophysiology, 2009Co-Authors: Shin-ichi Iwasaki, Y. E. Smulders, Ann M. Burgess, Yasuhiro Chihara, Gabor Michael Halmagyi, Ian S. Curthoys, Toshiaki MurofushiAbstract:Objective: The n10 component (n10) of the ocular Vestibular evoked myogenic potential (oVEMP) to brief bone conducted vibration (BCV) of the forehead at Fz is probably caused by the vibration selectively activating Vestibular otolithic receptors. If the n10 is due primarily to utricular activation then diseases which affect only the superior division of the Vestibular Nerve (SVN) should reduce or eliminate n10. Methods: The n10 component of the oVEMP was measured in 13 patients with unilateral SVN but with inferior Vestibular Nerve function preserved. Results: We compared the n10 to BCV of these 13 SVN patients to previously published data for healthy subjects and patients after complete unilateral Vestibular loss. We found that in 12 out of the 13 patients with SVN, n10 was markedly reduced or absent under the contralesional eye. Conclusion: Since all utricular afferents course in the superior Vestibular Nerve and in 12/13 of these patients the n10 was reduced we conclude that the n10 component of the oVEMP to BCV is probably mediated by the superior Vestibular Nerve and probably due to activation of mainly utricular receptors. Significance: The n10 appears to be a simple new test of superior Vestibular Nerve and probably mainly utricular function. © 2008 International Federation of Clinical Neurophysiology.
Ian S. Curthoys - One of the best experts on this subject based on the ideXlab platform.
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the ocular Vestibular evoked myogenic potential to air conducted sound probable superior Vestibular Nerve origin
Clinical Neurophysiology, 2011Co-Authors: Ian S. Curthoys, Munetaka Ushio, Shin-ichi Iwasaki, Yasuhiro Chihara, Leigh A. Mcgarvie, Ann M. BurgessAbstract:Abstract Objective Intense air-conducted sound (ACS) elicits an ocular Vestibular-evoked myogenic potential (oVEMP), and it has been suggested that it does so by stimulating saccular receptors and afferents in the inferior Vestibular Nerve and so activating a crossed sacculo-ocular pathway. Bone conducted vibration (BCV) also elicits an oVEMP probably by activating utricular receptors and a crossed utriculo-ocular pathway. Are there two separate pathways mediating oVEMPs for ACS and BCV? If saccular receptors and afferents are primarily responsible for the oVEMP to ACS, then the oVEMP to ACS should be normal in patients with reduced or absent utricular function – unilateral superior Vestibular neuritis (SVN). If utricular receptors and afferents are primarily responsible for oVEMP n10, then oVEMP to ACS should be reduced or absent in SVN patients, and in these patients there should be a close relationship between the size of the oVEMP n10 to BCV and to ACS. Methods The n10 component of the oVEMP to 500 Hz BCV and to 500 Hz ACS was recorded in 10 patients with unilateral SVN but who had saccular and inferior Vestibular Nerve function preserved, as shown by their normal cVEMP responses to ACS. Results In SVN patients with normal saccular and inferior Vestibular Nerve function, the oVEMP n10 in response to ACS was reduced or absent. Across SVN patients there was a very close correspondence between the size of oVEMP n10 for ACS and for BCV. Conclusions The n10 component of the oVEMP to ACS is probably mediated predominantly by the superior Vestibular Nerve and so most likely by utricular receptors and afferents. Significance The n10 component of the oVEMP to either ACS or BCV probably indicates mainly superior Vestibular Nerve function.
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The ocular Vestibular-evoked myogenic potential to air-conducted sound; probable superior Vestibular Nerve origin
Clinical Neurophysiology, 2011Co-Authors: Ian S. Curthoys, Munetaka Ushio, Shin-ichi Iwasaki, Yasuhiro Chihara, Leigh A. Mcgarvie, Ann M. BurgessAbstract:Objective: Intense air-conducted sound (ACS) elicits an ocular Vestibular-evoked myogenic potential (oVEMP), and it has been suggested that it does so by stimulating saccular receptors and afferents in the inferior Vestibular Nerve and so activating a crossed sacculo-ocular pathway. Bone conducted vibration (BCV) also elicits an oVEMP probably by activating utricular receptors and a crossed utriculo-ocular pathway. Are there two separate pathways mediating oVEMPs for ACS and BCV? If saccular receptors and afferents are primarily responsible for the oVEMP to ACS, then the oVEMP to ACS should be normal in patients with reduced or absent utricular function - unilateral superior Vestibular neuritis (SVN). If utricular receptors and afferents are primarily responsible for oVEMP n10, then oVEMP to ACS should be reduced or absent in SVN patients, and in these patients there should be a close relationship between the size of the oVEMP n10 to BCV and to ACS. Methods: The n10 component of the oVEMP to 500. Hz BCV and to 500. Hz ACS was recorded in 10 patients with unilateral SVN but who had saccular and inferior Vestibular Nerve function preserved, as shown by their normal cVEMP responses to ACS. Results: In SVN patients with normal saccular and inferior Vestibular Nerve function, the oVEMP n10 in response to ACS was reduced or absent. Across SVN patients there was a very close correspondence between the size of oVEMP n10 for ACS and for BCV. Conclusions: The n10 component of the oVEMP to ACS is probably mediated predominantly by the superior Vestibular Nerve and so most likely by utricular receptors and afferents. Significance: The n10 component of the oVEMP to either ACS or BCV probably indicates mainly superior Vestibular Nerve function. © 2010 International Federation of Clinical Neurophysiology.
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the role of the superior Vestibular Nerve in generating ocular Vestibular evoked myogenic potentials to bone conducted vibration at fz
Clinical Neurophysiology, 2009Co-Authors: Shin-ichi Iwasaki, Y. E. Smulders, Ann M. Burgess, Yasuhiro Chihara, Gabor Michael Halmagyi, Ian S. Curthoys, Toshiaki MurofushiAbstract:Objective: The n10 component (n10) of the ocular Vestibular evoked myogenic potential (oVEMP) to brief bone conducted vibration (BCV) of the forehead at Fz is probably caused by the vibration selectively activating Vestibular otolithic receptors. If the n10 is due primarily to utricular activation then diseases which affect only the superior division of the Vestibular Nerve (SVN) should reduce or eliminate n10. Methods: The n10 component of the oVEMP was measured in 13 patients with unilateral SVN but with inferior Vestibular Nerve function preserved. Results: We compared the n10 to BCV of these 13 SVN patients to previously published data for healthy subjects and patients after complete unilateral Vestibular loss. We found that in 12 out of the 13 patients with SVN, n10 was markedly reduced or absent under the contralesional eye. Conclusion: Since all utricular afferents course in the superior Vestibular Nerve and in 12/13 of these patients the n10 was reduced we conclude that the n10 component of the oVEMP to BCV is probably mediated by the superior Vestibular Nerve and probably due to activation of mainly utricular receptors. Significance: The n10 appears to be a simple new test of superior Vestibular Nerve and probably mainly utricular function.
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The role of the superior Vestibular Nerve in generating ocular Vestibular-evoked myogenic potentials to bone conducted vibration at Fz
Clinical Neurophysiology, 2009Co-Authors: Shin-ichi Iwasaki, Y. E. Smulders, Ann M. Burgess, Yasuhiro Chihara, Gabor Michael Halmagyi, Ian S. Curthoys, Toshiaki MurofushiAbstract:Objective: The n10 component (n10) of the ocular Vestibular evoked myogenic potential (oVEMP) to brief bone conducted vibration (BCV) of the forehead at Fz is probably caused by the vibration selectively activating Vestibular otolithic receptors. If the n10 is due primarily to utricular activation then diseases which affect only the superior division of the Vestibular Nerve (SVN) should reduce or eliminate n10. Methods: The n10 component of the oVEMP was measured in 13 patients with unilateral SVN but with inferior Vestibular Nerve function preserved. Results: We compared the n10 to BCV of these 13 SVN patients to previously published data for healthy subjects and patients after complete unilateral Vestibular loss. We found that in 12 out of the 13 patients with SVN, n10 was markedly reduced or absent under the contralesional eye. Conclusion: Since all utricular afferents course in the superior Vestibular Nerve and in 12/13 of these patients the n10 was reduced we conclude that the n10 component of the oVEMP to BCV is probably mediated by the superior Vestibular Nerve and probably due to activation of mainly utricular receptors. Significance: The n10 appears to be a simple new test of superior Vestibular Nerve and probably mainly utricular function. © 2008 International Federation of Clinical Neurophysiology.
Shin-ichi Iwasaki - One of the best experts on this subject based on the ideXlab platform.
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characteristics of vertigo and the affected Vestibular Nerve systems in idiopathic bilateral vestibulopathy
Acta Oto-laryngologica, 2016Co-Authors: Chisato Fujimoto, Makoto Kinoshita, Teru Kamogashira, Naoya Egami, Keiko Sugasawa, Tatsuya Yamasoba, Shin-ichi IwasakiAbstract:AbstractConclusion: Vertigo attacks in IBV patients involving both the superior and inferior Vestibular Nerve systems were significantly more severe than vertigo attacks in patients with selective involvement of the inferior Vestibular Nerve system alone. Objective: To investigate the relationship between the frequency and duration of vertigo and the affected Vestibular Nerve system in idiopathic bilateral vestibulopathy (IBV). Methods: This study categorized 44 IBV patients into the following three sub-groups according to the affected Vestibular Nerve system: superior, inferior, and mixed type. These patients were also categorized into the following three sub-groups according to their clinical time course: progressive type showing no episodes of vertigo, sequential type showing recurrent vertigo attacks and single-attack type showing a single episode of vertigo. Results: Ten, 11 and 23 patients were classified as the superior, the inferior, and the mixed type, respectively. Seventeen, 23, and four patien...
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the ocular Vestibular evoked myogenic potential to air conducted sound probable superior Vestibular Nerve origin
Clinical Neurophysiology, 2011Co-Authors: Ian S. Curthoys, Munetaka Ushio, Shin-ichi Iwasaki, Yasuhiro Chihara, Leigh A. Mcgarvie, Ann M. BurgessAbstract:Abstract Objective Intense air-conducted sound (ACS) elicits an ocular Vestibular-evoked myogenic potential (oVEMP), and it has been suggested that it does so by stimulating saccular receptors and afferents in the inferior Vestibular Nerve and so activating a crossed sacculo-ocular pathway. Bone conducted vibration (BCV) also elicits an oVEMP probably by activating utricular receptors and a crossed utriculo-ocular pathway. Are there two separate pathways mediating oVEMPs for ACS and BCV? If saccular receptors and afferents are primarily responsible for the oVEMP to ACS, then the oVEMP to ACS should be normal in patients with reduced or absent utricular function – unilateral superior Vestibular neuritis (SVN). If utricular receptors and afferents are primarily responsible for oVEMP n10, then oVEMP to ACS should be reduced or absent in SVN patients, and in these patients there should be a close relationship between the size of the oVEMP n10 to BCV and to ACS. Methods The n10 component of the oVEMP to 500 Hz BCV and to 500 Hz ACS was recorded in 10 patients with unilateral SVN but who had saccular and inferior Vestibular Nerve function preserved, as shown by their normal cVEMP responses to ACS. Results In SVN patients with normal saccular and inferior Vestibular Nerve function, the oVEMP n10 in response to ACS was reduced or absent. Across SVN patients there was a very close correspondence between the size of oVEMP n10 for ACS and for BCV. Conclusions The n10 component of the oVEMP to ACS is probably mediated predominantly by the superior Vestibular Nerve and so most likely by utricular receptors and afferents. Significance The n10 component of the oVEMP to either ACS or BCV probably indicates mainly superior Vestibular Nerve function.
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The ocular Vestibular-evoked myogenic potential to air-conducted sound; probable superior Vestibular Nerve origin
Clinical Neurophysiology, 2011Co-Authors: Ian S. Curthoys, Munetaka Ushio, Shin-ichi Iwasaki, Yasuhiro Chihara, Leigh A. Mcgarvie, Ann M. BurgessAbstract:Objective: Intense air-conducted sound (ACS) elicits an ocular Vestibular-evoked myogenic potential (oVEMP), and it has been suggested that it does so by stimulating saccular receptors and afferents in the inferior Vestibular Nerve and so activating a crossed sacculo-ocular pathway. Bone conducted vibration (BCV) also elicits an oVEMP probably by activating utricular receptors and a crossed utriculo-ocular pathway. Are there two separate pathways mediating oVEMPs for ACS and BCV? If saccular receptors and afferents are primarily responsible for the oVEMP to ACS, then the oVEMP to ACS should be normal in patients with reduced or absent utricular function - unilateral superior Vestibular neuritis (SVN). If utricular receptors and afferents are primarily responsible for oVEMP n10, then oVEMP to ACS should be reduced or absent in SVN patients, and in these patients there should be a close relationship between the size of the oVEMP n10 to BCV and to ACS. Methods: The n10 component of the oVEMP to 500. Hz BCV and to 500. Hz ACS was recorded in 10 patients with unilateral SVN but who had saccular and inferior Vestibular Nerve function preserved, as shown by their normal cVEMP responses to ACS. Results: In SVN patients with normal saccular and inferior Vestibular Nerve function, the oVEMP n10 in response to ACS was reduced or absent. Across SVN patients there was a very close correspondence between the size of oVEMP n10 for ACS and for BCV. Conclusions: The n10 component of the oVEMP to ACS is probably mediated predominantly by the superior Vestibular Nerve and so most likely by utricular receptors and afferents. Significance: The n10 component of the oVEMP to either ACS or BCV probably indicates mainly superior Vestibular Nerve function. © 2010 International Federation of Clinical Neurophysiology.
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the role of the superior Vestibular Nerve in generating ocular Vestibular evoked myogenic potentials to bone conducted vibration at fz
Clinical Neurophysiology, 2009Co-Authors: Shin-ichi Iwasaki, Y. E. Smulders, Ann M. Burgess, Yasuhiro Chihara, Gabor Michael Halmagyi, Ian S. Curthoys, Toshiaki MurofushiAbstract:Objective: The n10 component (n10) of the ocular Vestibular evoked myogenic potential (oVEMP) to brief bone conducted vibration (BCV) of the forehead at Fz is probably caused by the vibration selectively activating Vestibular otolithic receptors. If the n10 is due primarily to utricular activation then diseases which affect only the superior division of the Vestibular Nerve (SVN) should reduce or eliminate n10. Methods: The n10 component of the oVEMP was measured in 13 patients with unilateral SVN but with inferior Vestibular Nerve function preserved. Results: We compared the n10 to BCV of these 13 SVN patients to previously published data for healthy subjects and patients after complete unilateral Vestibular loss. We found that in 12 out of the 13 patients with SVN, n10 was markedly reduced or absent under the contralesional eye. Conclusion: Since all utricular afferents course in the superior Vestibular Nerve and in 12/13 of these patients the n10 was reduced we conclude that the n10 component of the oVEMP to BCV is probably mediated by the superior Vestibular Nerve and probably due to activation of mainly utricular receptors. Significance: The n10 appears to be a simple new test of superior Vestibular Nerve and probably mainly utricular function.
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The role of the superior Vestibular Nerve in generating ocular Vestibular-evoked myogenic potentials to bone conducted vibration at Fz
Clinical Neurophysiology, 2009Co-Authors: Shin-ichi Iwasaki, Y. E. Smulders, Ann M. Burgess, Yasuhiro Chihara, Gabor Michael Halmagyi, Ian S. Curthoys, Toshiaki MurofushiAbstract:Objective: The n10 component (n10) of the ocular Vestibular evoked myogenic potential (oVEMP) to brief bone conducted vibration (BCV) of the forehead at Fz is probably caused by the vibration selectively activating Vestibular otolithic receptors. If the n10 is due primarily to utricular activation then diseases which affect only the superior division of the Vestibular Nerve (SVN) should reduce or eliminate n10. Methods: The n10 component of the oVEMP was measured in 13 patients with unilateral SVN but with inferior Vestibular Nerve function preserved. Results: We compared the n10 to BCV of these 13 SVN patients to previously published data for healthy subjects and patients after complete unilateral Vestibular loss. We found that in 12 out of the 13 patients with SVN, n10 was markedly reduced or absent under the contralesional eye. Conclusion: Since all utricular afferents course in the superior Vestibular Nerve and in 12/13 of these patients the n10 was reduced we conclude that the n10 component of the oVEMP to BCV is probably mediated by the superior Vestibular Nerve and probably due to activation of mainly utricular receptors. Significance: The n10 appears to be a simple new test of superior Vestibular Nerve and probably mainly utricular function. © 2008 International Federation of Clinical Neurophysiology.
Toshiaki Murofushi - One of the best experts on this subject based on the ideXlab platform.
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the role of the superior Vestibular Nerve in generating ocular Vestibular evoked myogenic potentials to bone conducted vibration at fz
Clinical Neurophysiology, 2009Co-Authors: Shin-ichi Iwasaki, Y. E. Smulders, Ann M. Burgess, Yasuhiro Chihara, Gabor Michael Halmagyi, Ian S. Curthoys, Toshiaki MurofushiAbstract:Objective: The n10 component (n10) of the ocular Vestibular evoked myogenic potential (oVEMP) to brief bone conducted vibration (BCV) of the forehead at Fz is probably caused by the vibration selectively activating Vestibular otolithic receptors. If the n10 is due primarily to utricular activation then diseases which affect only the superior division of the Vestibular Nerve (SVN) should reduce or eliminate n10. Methods: The n10 component of the oVEMP was measured in 13 patients with unilateral SVN but with inferior Vestibular Nerve function preserved. Results: We compared the n10 to BCV of these 13 SVN patients to previously published data for healthy subjects and patients after complete unilateral Vestibular loss. We found that in 12 out of the 13 patients with SVN, n10 was markedly reduced or absent under the contralesional eye. Conclusion: Since all utricular afferents course in the superior Vestibular Nerve and in 12/13 of these patients the n10 was reduced we conclude that the n10 component of the oVEMP to BCV is probably mediated by the superior Vestibular Nerve and probably due to activation of mainly utricular receptors. Significance: The n10 appears to be a simple new test of superior Vestibular Nerve and probably mainly utricular function.
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The role of the superior Vestibular Nerve in generating ocular Vestibular-evoked myogenic potentials to bone conducted vibration at Fz
Clinical Neurophysiology, 2009Co-Authors: Shin-ichi Iwasaki, Y. E. Smulders, Ann M. Burgess, Yasuhiro Chihara, Gabor Michael Halmagyi, Ian S. Curthoys, Toshiaki MurofushiAbstract:Objective: The n10 component (n10) of the ocular Vestibular evoked myogenic potential (oVEMP) to brief bone conducted vibration (BCV) of the forehead at Fz is probably caused by the vibration selectively activating Vestibular otolithic receptors. If the n10 is due primarily to utricular activation then diseases which affect only the superior division of the Vestibular Nerve (SVN) should reduce or eliminate n10. Methods: The n10 component of the oVEMP was measured in 13 patients with unilateral SVN but with inferior Vestibular Nerve function preserved. Results: We compared the n10 to BCV of these 13 SVN patients to previously published data for healthy subjects and patients after complete unilateral Vestibular loss. We found that in 12 out of the 13 patients with SVN, n10 was markedly reduced or absent under the contralesional eye. Conclusion: Since all utricular afferents course in the superior Vestibular Nerve and in 12/13 of these patients the n10 was reduced we conclude that the n10 component of the oVEMP to BCV is probably mediated by the superior Vestibular Nerve and probably due to activation of mainly utricular receptors. Significance: The n10 appears to be a simple new test of superior Vestibular Nerve and probably mainly utricular function. © 2008 International Federation of Clinical Neurophysiology.
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absent Vestibular evoked myogenic potentials in Vestibular neurolabyrinthitis an indicator of inferior Vestibular Nerve involvement
Archives of Otolaryngology-head & Neck Surgery, 1996Co-Authors: Toshiaki Murofushi, Gabor Michael Halmagyi, R A Yavor, James G ColebatchAbstract:Background: Benign paroxysmal positioning vertigo (BPPV) is generally thought to be caused by canalolithiasis in the posterior semicircular canal, an organ that is innervated by the inferior Vestibular Nerve. We hypothesized that absent Vestibular evoked myogenic potentials (VEMPs) would indicate involvement of the inferior Vestibular Nerve and that posterior semicircular canal—type BPPV could not develop after Vestibular neurolabyrinthitis (VNL) in patients with absent VEMPs. Objective: To find out if VEMPs could be helpful in evaluating involvement of the inferior Vestibular Nerve in acute VNL. Design: We reviewed the VEMP findings in 47 patients (34 men and 13 women) with acute VNL, 10 of whom had then developed posterior semicircular canal—type BPPV. Results: While p13-n23, the first positive-negative peak of the VEMP, was ipsilaterally present on stimulation of the unaffected side in all patients, it was absent on the affected side in 16 patients (34%). The absence or presence of p13-n23 was independent of the results of caloric tests, pure tone audiometry, and auditory brain-stem responses. Typical posterior semicircular canal BPPV developed in 10 of the 47 patients after the acute attack of VNL, always on the same side as the neurolabyrinthitis. The p13-n23 potentials were preserved on stimulation of the affected ear in all 10 patients with BPPV. Conclusions: These results suggest that if VEMPs are absent from an ear that has suffered acute VNL, then posterior semicircular canal BPPV is unlikely to develop as a consequence of the VNL. The reason for this appears to be that the absence of VEMPs is due to involvement of the inferior Vestibular Nerve or involvement of the structures that it innervates. Arch Otolaryngol Head Neck Surg. 1996;122:845-848
Yasuhiro Chihara - One of the best experts on this subject based on the ideXlab platform.
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the ocular Vestibular evoked myogenic potential to air conducted sound probable superior Vestibular Nerve origin
Clinical Neurophysiology, 2011Co-Authors: Ian S. Curthoys, Munetaka Ushio, Shin-ichi Iwasaki, Yasuhiro Chihara, Leigh A. Mcgarvie, Ann M. BurgessAbstract:Abstract Objective Intense air-conducted sound (ACS) elicits an ocular Vestibular-evoked myogenic potential (oVEMP), and it has been suggested that it does so by stimulating saccular receptors and afferents in the inferior Vestibular Nerve and so activating a crossed sacculo-ocular pathway. Bone conducted vibration (BCV) also elicits an oVEMP probably by activating utricular receptors and a crossed utriculo-ocular pathway. Are there two separate pathways mediating oVEMPs for ACS and BCV? If saccular receptors and afferents are primarily responsible for the oVEMP to ACS, then the oVEMP to ACS should be normal in patients with reduced or absent utricular function – unilateral superior Vestibular neuritis (SVN). If utricular receptors and afferents are primarily responsible for oVEMP n10, then oVEMP to ACS should be reduced or absent in SVN patients, and in these patients there should be a close relationship between the size of the oVEMP n10 to BCV and to ACS. Methods The n10 component of the oVEMP to 500 Hz BCV and to 500 Hz ACS was recorded in 10 patients with unilateral SVN but who had saccular and inferior Vestibular Nerve function preserved, as shown by their normal cVEMP responses to ACS. Results In SVN patients with normal saccular and inferior Vestibular Nerve function, the oVEMP n10 in response to ACS was reduced or absent. Across SVN patients there was a very close correspondence between the size of oVEMP n10 for ACS and for BCV. Conclusions The n10 component of the oVEMP to ACS is probably mediated predominantly by the superior Vestibular Nerve and so most likely by utricular receptors and afferents. Significance The n10 component of the oVEMP to either ACS or BCV probably indicates mainly superior Vestibular Nerve function.
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The ocular Vestibular-evoked myogenic potential to air-conducted sound; probable superior Vestibular Nerve origin
Clinical Neurophysiology, 2011Co-Authors: Ian S. Curthoys, Munetaka Ushio, Shin-ichi Iwasaki, Yasuhiro Chihara, Leigh A. Mcgarvie, Ann M. BurgessAbstract:Objective: Intense air-conducted sound (ACS) elicits an ocular Vestibular-evoked myogenic potential (oVEMP), and it has been suggested that it does so by stimulating saccular receptors and afferents in the inferior Vestibular Nerve and so activating a crossed sacculo-ocular pathway. Bone conducted vibration (BCV) also elicits an oVEMP probably by activating utricular receptors and a crossed utriculo-ocular pathway. Are there two separate pathways mediating oVEMPs for ACS and BCV? If saccular receptors and afferents are primarily responsible for the oVEMP to ACS, then the oVEMP to ACS should be normal in patients with reduced or absent utricular function - unilateral superior Vestibular neuritis (SVN). If utricular receptors and afferents are primarily responsible for oVEMP n10, then oVEMP to ACS should be reduced or absent in SVN patients, and in these patients there should be a close relationship between the size of the oVEMP n10 to BCV and to ACS. Methods: The n10 component of the oVEMP to 500. Hz BCV and to 500. Hz ACS was recorded in 10 patients with unilateral SVN but who had saccular and inferior Vestibular Nerve function preserved, as shown by their normal cVEMP responses to ACS. Results: In SVN patients with normal saccular and inferior Vestibular Nerve function, the oVEMP n10 in response to ACS was reduced or absent. Across SVN patients there was a very close correspondence between the size of oVEMP n10 for ACS and for BCV. Conclusions: The n10 component of the oVEMP to ACS is probably mediated predominantly by the superior Vestibular Nerve and so most likely by utricular receptors and afferents. Significance: The n10 component of the oVEMP to either ACS or BCV probably indicates mainly superior Vestibular Nerve function. © 2010 International Federation of Clinical Neurophysiology.
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the role of the superior Vestibular Nerve in generating ocular Vestibular evoked myogenic potentials to bone conducted vibration at fz
Clinical Neurophysiology, 2009Co-Authors: Shin-ichi Iwasaki, Y. E. Smulders, Ann M. Burgess, Yasuhiro Chihara, Gabor Michael Halmagyi, Ian S. Curthoys, Toshiaki MurofushiAbstract:Objective: The n10 component (n10) of the ocular Vestibular evoked myogenic potential (oVEMP) to brief bone conducted vibration (BCV) of the forehead at Fz is probably caused by the vibration selectively activating Vestibular otolithic receptors. If the n10 is due primarily to utricular activation then diseases which affect only the superior division of the Vestibular Nerve (SVN) should reduce or eliminate n10. Methods: The n10 component of the oVEMP was measured in 13 patients with unilateral SVN but with inferior Vestibular Nerve function preserved. Results: We compared the n10 to BCV of these 13 SVN patients to previously published data for healthy subjects and patients after complete unilateral Vestibular loss. We found that in 12 out of the 13 patients with SVN, n10 was markedly reduced or absent under the contralesional eye. Conclusion: Since all utricular afferents course in the superior Vestibular Nerve and in 12/13 of these patients the n10 was reduced we conclude that the n10 component of the oVEMP to BCV is probably mediated by the superior Vestibular Nerve and probably due to activation of mainly utricular receptors. Significance: The n10 appears to be a simple new test of superior Vestibular Nerve and probably mainly utricular function.
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The role of the superior Vestibular Nerve in generating ocular Vestibular-evoked myogenic potentials to bone conducted vibration at Fz
Clinical Neurophysiology, 2009Co-Authors: Shin-ichi Iwasaki, Y. E. Smulders, Ann M. Burgess, Yasuhiro Chihara, Gabor Michael Halmagyi, Ian S. Curthoys, Toshiaki MurofushiAbstract:Objective: The n10 component (n10) of the ocular Vestibular evoked myogenic potential (oVEMP) to brief bone conducted vibration (BCV) of the forehead at Fz is probably caused by the vibration selectively activating Vestibular otolithic receptors. If the n10 is due primarily to utricular activation then diseases which affect only the superior division of the Vestibular Nerve (SVN) should reduce or eliminate n10. Methods: The n10 component of the oVEMP was measured in 13 patients with unilateral SVN but with inferior Vestibular Nerve function preserved. Results: We compared the n10 to BCV of these 13 SVN patients to previously published data for healthy subjects and patients after complete unilateral Vestibular loss. We found that in 12 out of the 13 patients with SVN, n10 was markedly reduced or absent under the contralesional eye. Conclusion: Since all utricular afferents course in the superior Vestibular Nerve and in 12/13 of these patients the n10 was reduced we conclude that the n10 component of the oVEMP to BCV is probably mediated by the superior Vestibular Nerve and probably due to activation of mainly utricular receptors. Significance: The n10 appears to be a simple new test of superior Vestibular Nerve and probably mainly utricular function. © 2008 International Federation of Clinical Neurophysiology.
