The Experts below are selected from a list of 105 Experts worldwide ranked by ideXlab platform
Kiyoshi Togawa - One of the best experts on this subject based on the ideXlab platform.
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Effect of unilateral section of cervical afferent nerve upon optokinetic response and Vestibular Nystagmus induced by sinusoidal rotation in guinea pigs.
Acta Oto-Laryngologica, 1998Co-Authors: Kazuo Ishikawa, Zensei Matsuzaki, Michinori Yokomizo, Nobuhisa Terada, Soichiroh Miyazaki, Kiyoshi TogawaAbstract:An experiment was carried out in guinea pigs to clarify the effect of unilateral section of cervical afferent nerve (C1-C3) upon optokinetic Nystagmus and Vestibular Nystagmus induced by sinusoidal rotation. To produce optokinetic Nystagmus and optokinetic after-Nystagmus, a random dot pattern was utilized as visual stimulation at a speed of 30°/s. As for Vestibular Nystagmus, sinusoidal rotation at a frequency of 0.1 Hz with an amplitude of 120° was used. Results showed that for about a week after the surgical section of the C1-C3 nerves, directional preponderance of the Vestibular Nystagmus was found toward the lesion side, whereas no significant change was obtained in optokinetic Nystagmus and optokinetic after Nystagmus. This asymmetric change of the Vestibular Nystagmus was compensated for within a week or two. Thus, unilateral section of the cervical afferent nerve produced only a temporary effect on the vestibulo-ocular reflex but it had no significant effect on the optokinetic response.
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Effect of unilateral section of cervical afferent nerve upon optokinetic response and Vestibular Nystagmus induced by sinusoidal rotation in guinea pigs.
Acta oto-laryngologica. Supplementum, 1998Co-Authors: Kazuo Ishikawa, Zensei Matsuzaki, Michinori Yokomizo, Nobuhisa Terada, Soichiroh Miyazaki, Kiyoshi TogawaAbstract:An experiment was carried out in guinea pigs to clarify the effect of unilateral section of cervical afferent nerve (C1-C3) upon optokinetic Nystagmus and Vestibular Nystagmus induced by sinusoidal rotation. To produce optokinetic Nystagmus and optokinetic after-Nystagmus, a random dot pattern was utilized as visual stimulation at a speed of 30 degrees/s. As for Vestibular Nystagmus, sinusoidal rotation at a frequency of 0.1 Hz with an amplitude of 120 degrees was used. Results showed that for about a week after the surgical section of the C1-C3 nerves, directional preponderance of the Vestibular Nystagmus was found toward the lesion side, whereas no significant change was obtained in optokinetic Nystagmus and optokinetic after Nystagmus. This asymmetric change of the Vestibular Nystagmus was compensated for within a week or two. Thus. unilateral section of the cervical afferent nerve produced only a temporary effect on the vestibulo-ocular reflex but it had no significant effect on the optokinetic response.
D. S. Zee - One of the best experts on this subject based on the ideXlab platform.
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Evidence of Normal Cerebellar Control of the Vestibulo-Ocular Reflex (VOR) in Children with High-Functioning Autism
Journal of Autism and Developmental Disorders, 2000Co-Authors: Melissa C. Goldberg, R. Landa, A. Lasker, L. Cooper, D. S. ZeeAbstract:The effect of “tilt-suppression” on post-rotatory Vestibular Nystagmus was investigated to assess the function of the caudal cerebellar vermis (lobules IX and X, or nodulus and uvula) in 13 school-age children with high-functioning autism (HFA) and 10 normal controls. Tilt-suppression of the vestibulo-ocular reflex (VOR) refers to the decreasing of the duration of post-rotatory Vestibular Nystagmus that occurs when the head is moved out of the plane in which it was located during the previous sustained constant-velocity rotation. The participant is rotated in a Vestibular chair with the head upright and then the head is tilted forward just after the chair stops rotating. Such tilt-suppression is impaired with lesions of the cerebellar nodulus and portions of the uvula. Results show that children with HFA have normal post-rotatory nystasmus with the head upright and normal attenuation of post-rotatory Nystagmus induced by head tilt. These behavioral findings suggest that lobules IX and X of the cerebellum are spared in high-functioning autism.
J Van Der Steen - One of the best experts on this subject based on the ideXlab platform.
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shortening of Vestibular Nystagmus in response to velocity steps by microinjection of carbachol in the rabbit s cerebellar flocculus
Experimental Brain Research, 1993Co-Authors: H S Tan, H Collewijn, J Van Der SteenAbstract:It has been proposed that a common velocity-storage mechanism is responsible for the prolongation of Vestibular Nystagmus beyond the duration of the change in firing frequency of primary Vestibular fibers in response to a step in velocity, and for the production of optokinetic afterNystagmus (OKAN). In a previous study, bilateral injection of the aselective cholinergic agonist carbachol in the flocculus shortened the duration of buildup of optokinetic Nystagmus (OKN) and the duration of OKAN, suggesting floccular involvement in velocity storage (Tan et al. 1992). In extension to that study of OKN, the present study assesses the effects of floccular carbachol on Vestibular Nystagmus in response to velocity steps. Our results show that injection of carbachol shortens the duration of Vestibular Nystagmus from about 13 to about 8 s; a finding which supports a common velocity-storage mechanism for optokinetic and Vestibular signals. We propose that the indistinguishable effects of carbachol on OKAN and Vestibular Nystagmus are due to modification of the transmission of an oculomotor corollary signal, which has been identified electrophysiologically in the flocculus.
Kazuo Ishikawa - One of the best experts on this subject based on the ideXlab platform.
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Effect of unilateral section of cervical afferent nerve upon optokinetic response and Vestibular Nystagmus induced by sinusoidal rotation in guinea pigs.
Acta Oto-Laryngologica, 1998Co-Authors: Kazuo Ishikawa, Zensei Matsuzaki, Michinori Yokomizo, Nobuhisa Terada, Soichiroh Miyazaki, Kiyoshi TogawaAbstract:An experiment was carried out in guinea pigs to clarify the effect of unilateral section of cervical afferent nerve (C1-C3) upon optokinetic Nystagmus and Vestibular Nystagmus induced by sinusoidal rotation. To produce optokinetic Nystagmus and optokinetic after-Nystagmus, a random dot pattern was utilized as visual stimulation at a speed of 30°/s. As for Vestibular Nystagmus, sinusoidal rotation at a frequency of 0.1 Hz with an amplitude of 120° was used. Results showed that for about a week after the surgical section of the C1-C3 nerves, directional preponderance of the Vestibular Nystagmus was found toward the lesion side, whereas no significant change was obtained in optokinetic Nystagmus and optokinetic after Nystagmus. This asymmetric change of the Vestibular Nystagmus was compensated for within a week or two. Thus, unilateral section of the cervical afferent nerve produced only a temporary effect on the vestibulo-ocular reflex but it had no significant effect on the optokinetic response.
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Effect of unilateral section of cervical afferent nerve upon optokinetic response and Vestibular Nystagmus induced by sinusoidal rotation in guinea pigs.
Acta oto-laryngologica. Supplementum, 1998Co-Authors: Kazuo Ishikawa, Zensei Matsuzaki, Michinori Yokomizo, Nobuhisa Terada, Soichiroh Miyazaki, Kiyoshi TogawaAbstract:An experiment was carried out in guinea pigs to clarify the effect of unilateral section of cervical afferent nerve (C1-C3) upon optokinetic Nystagmus and Vestibular Nystagmus induced by sinusoidal rotation. To produce optokinetic Nystagmus and optokinetic after-Nystagmus, a random dot pattern was utilized as visual stimulation at a speed of 30 degrees/s. As for Vestibular Nystagmus, sinusoidal rotation at a frequency of 0.1 Hz with an amplitude of 120 degrees was used. Results showed that for about a week after the surgical section of the C1-C3 nerves, directional preponderance of the Vestibular Nystagmus was found toward the lesion side, whereas no significant change was obtained in optokinetic Nystagmus and optokinetic after Nystagmus. This asymmetric change of the Vestibular Nystagmus was compensated for within a week or two. Thus. unilateral section of the cervical afferent nerve produced only a temporary effect on the vestibulo-ocular reflex but it had no significant effect on the optokinetic response.
John E Fitzgerald - One of the best experts on this subject based on the ideXlab platform.
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The effect of mental alerting on peripheral Vestibular Nystagmus during spontaneous, gaze (30 degrees left, 30 degrees right) and body positional (left & right lateral lying) testing using electronystagmography (ENG).
International journal of audiology, 2008Co-Authors: Tracey N. Mcgovern, John E FitzgeraldAbstract:The performance of mental alerting during caloric testing has always been considered important, however its use/benefit during electronystagmography (ENG)/videonystagmography (VNG) testing has been questioned. The aim of this study was to investigate the effect of mental alerting tasks on peripheral type Vestibular Nystagmus recorded during ENG. Thirty patients with significant spontaneous/gaze or positional Nystagmus (slow phase velocity >or= 6 degrees /s) were recruited from consecutive referrals for Vestibular assessment. Nystagmus was recorded by ENG both in the presence and absence of mental alerting for each patient. Investigation of Nystagmus by analysis of variance (ANOVA) revealed significantly larger Nystagmus (higher value SPV) with mental alerting than with no alerting (p
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the effect of mental alerting on peripheral Vestibular Nystagmus during spontaneous gaze 30 degrees left 30 degrees right and body positional left right lateral lying testing using electronystagmography eng
International Journal of Audiology, 2008Co-Authors: Tracey N. Mcgovern, John E FitzgeraldAbstract:The performance of mental alerting during caloric testing has always been considered important, however its use/benefit during electronystagmography (ENG)/videonystagmography (VNG) testing has been questioned. The aim of this study was to investigate the effect of mental alerting tasks on peripheral type Vestibular Nystagmus recorded during ENG. Thirty patients with significant spontaneous/gaze or positional Nystagmus (slow phase velocity >or= 6 degrees /s) were recruited from consecutive referrals for Vestibular assessment. Nystagmus was recorded by ENG both in the presence and absence of mental alerting for each patient. Investigation of Nystagmus by analysis of variance (ANOVA) revealed significantly larger Nystagmus (higher value SPV) with mental alerting than with no alerting (p<0.001), and for some patients Nystagmus traces were reduced to a flat line (no Nystagmus) with no alerting. The study demonstrates the importance of mental alerting in helping overcome central suppression of Nystagmus and highlights its importance to help identify peripheral type Nystagmus during ENG.
