The Experts below are selected from a list of 609 Experts worldwide ranked by ideXlab platform
Baoan Song - One of the best experts on this subject based on the ideXlab platform.
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Synthesis and Antiviral Bioactivity of Novel (1E, 4E)‐1‐Aryl‐5‐(2‐(quinazolin‐4‐yloxy)phenyl)‐1,4‐pentadien‐3‐one Derivatives.
ChemInform, 2013Co-Authors: Hui Luo, Jiaju Liu, Linhong Jin, Zhen Chen, Song Yang, Baoan SongAbstract:For the first time it is demonstrates that the title compounds can be used to develop potential Virucides for plants.
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Synthesis and antiviral bioactivity of novel (1E, 4E)-1-aryl-5-(2-(quinazolin-4-yloxy)phenyl)-1,4-pentadien-3-one derivatives
European Journal of Medicinal Chemistry, 2013Co-Authors: Hui Luo, Jiaju Liu, Linhong Jin, Zhen Chen, Song Yang, Baoan SongAbstract:Abstract A series of novel (1E, 4E)-1-aryl-5-[2-(quinazolin-4-yloxy)phenyl]-1,4-pentadien-3-one derivatives were designed and synthesized by reacting substituent aldehyde with intermediates 4a–f. Antiviral bioassays indicated that most of the compounds exhibited promising ex vivo antiviral bioactivities against tobacco mosaic virus (TMV) and cucumber mosaic virus (CMV) at 500 μg/mL. The relationship between structure and antiviral activity was also discussed. Compounds 5a, 6e, and 6g could possess appreciable protective bioactivities on TMV ex vivo by approximately 50% (EC50) at 257.7, 320.7 and 243.3 μg/mL. This study is the first to demonstrate that (1E, 4E)-1-aryl-5-(2-(quinazolin-4-yloxy)phenyl)-1,4-pentadien-3-one can be used to develop potential Virucides for plants.
Hui Luo - One of the best experts on this subject based on the ideXlab platform.
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Synthesis and Antiviral Bioactivity of Novel (1E, 4E)‐1‐Aryl‐5‐(2‐(quinazolin‐4‐yloxy)phenyl)‐1,4‐pentadien‐3‐one Derivatives.
ChemInform, 2013Co-Authors: Hui Luo, Jiaju Liu, Linhong Jin, Zhen Chen, Song Yang, Baoan SongAbstract:For the first time it is demonstrates that the title compounds can be used to develop potential Virucides for plants.
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Synthesis and antiviral bioactivity of novel (1E, 4E)-1-aryl-5-(2-(quinazolin-4-yloxy)phenyl)-1,4-pentadien-3-one derivatives
European Journal of Medicinal Chemistry, 2013Co-Authors: Hui Luo, Jiaju Liu, Linhong Jin, Zhen Chen, Song Yang, Baoan SongAbstract:Abstract A series of novel (1E, 4E)-1-aryl-5-[2-(quinazolin-4-yloxy)phenyl]-1,4-pentadien-3-one derivatives were designed and synthesized by reacting substituent aldehyde with intermediates 4a–f. Antiviral bioassays indicated that most of the compounds exhibited promising ex vivo antiviral bioactivities against tobacco mosaic virus (TMV) and cucumber mosaic virus (CMV) at 500 μg/mL. The relationship between structure and antiviral activity was also discussed. Compounds 5a, 6e, and 6g could possess appreciable protective bioactivities on TMV ex vivo by approximately 50% (EC50) at 257.7, 320.7 and 243.3 μg/mL. This study is the first to demonstrate that (1E, 4E)-1-aryl-5-(2-(quinazolin-4-yloxy)phenyl)-1,4-pentadien-3-one can be used to develop potential Virucides for plants.
Jiaju Liu - One of the best experts on this subject based on the ideXlab platform.
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Schisanhenol derivatives and their biological evaluation against tobacco mosaic virus (TMV).
Fitoterapia, 2015Co-Authors: Qing-yao Wang, Jiaju Liu, Lu‐lu Deng, Jian-xin Zhang, Xiao-jiang HaoAbstract:Abstract Schisanhenol (Sol) was isolated from Schisandra rubriflora, and a series of derivatives (1–16, 15a-16a, and 15b-16b) were designed and prepared by chemical modification. The curative and protective effects of these dibenzocyclooctadiene lignan analogues against tobacco mosaic virus (TMV) were evaluated. Most analogues exhibited stronger protective effects than the positive control ningnanmycin. Dibromoschisanhenol (6) at 0.25 mM exhibited the strongest protective activity (83.5 ± 1.8% at 0.25 mM), and 14-(3, 5-dibenzyloxy)-benzoyloxyschisanhenol (16) showed a significant curative effect (78.0 ± 3.8% at 0.15 mM) that was much stronger than that of the commercial virucide ningnanmycin. This study is the first to demonstrate that natural dibenzocyclooctadiene lignans and analogues are active against plant viruses.
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Synthesis and Antiviral Bioactivity of Novel (1E, 4E)‐1‐Aryl‐5‐(2‐(quinazolin‐4‐yloxy)phenyl)‐1,4‐pentadien‐3‐one Derivatives.
ChemInform, 2013Co-Authors: Hui Luo, Jiaju Liu, Linhong Jin, Zhen Chen, Song Yang, Baoan SongAbstract:For the first time it is demonstrates that the title compounds can be used to develop potential Virucides for plants.
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Synthesis and antiviral bioactivity of novel (1E, 4E)-1-aryl-5-(2-(quinazolin-4-yloxy)phenyl)-1,4-pentadien-3-one derivatives
European Journal of Medicinal Chemistry, 2013Co-Authors: Hui Luo, Jiaju Liu, Linhong Jin, Zhen Chen, Song Yang, Baoan SongAbstract:Abstract A series of novel (1E, 4E)-1-aryl-5-[2-(quinazolin-4-yloxy)phenyl]-1,4-pentadien-3-one derivatives were designed and synthesized by reacting substituent aldehyde with intermediates 4a–f. Antiviral bioassays indicated that most of the compounds exhibited promising ex vivo antiviral bioactivities against tobacco mosaic virus (TMV) and cucumber mosaic virus (CMV) at 500 μg/mL. The relationship between structure and antiviral activity was also discussed. Compounds 5a, 6e, and 6g could possess appreciable protective bioactivities on TMV ex vivo by approximately 50% (EC50) at 257.7, 320.7 and 243.3 μg/mL. This study is the first to demonstrate that (1E, 4E)-1-aryl-5-(2-(quinazolin-4-yloxy)phenyl)-1,4-pentadien-3-one can be used to develop potential Virucides for plants.
Linhong Jin - One of the best experts on this subject based on the ideXlab platform.
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Synthesis and Antiviral Bioactivity of Novel (1E, 4E)‐1‐Aryl‐5‐(2‐(quinazolin‐4‐yloxy)phenyl)‐1,4‐pentadien‐3‐one Derivatives.
ChemInform, 2013Co-Authors: Hui Luo, Jiaju Liu, Linhong Jin, Zhen Chen, Song Yang, Baoan SongAbstract:For the first time it is demonstrates that the title compounds can be used to develop potential Virucides for plants.
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Synthesis and antiviral bioactivity of novel (1E, 4E)-1-aryl-5-(2-(quinazolin-4-yloxy)phenyl)-1,4-pentadien-3-one derivatives
European Journal of Medicinal Chemistry, 2013Co-Authors: Hui Luo, Jiaju Liu, Linhong Jin, Zhen Chen, Song Yang, Baoan SongAbstract:Abstract A series of novel (1E, 4E)-1-aryl-5-[2-(quinazolin-4-yloxy)phenyl]-1,4-pentadien-3-one derivatives were designed and synthesized by reacting substituent aldehyde with intermediates 4a–f. Antiviral bioassays indicated that most of the compounds exhibited promising ex vivo antiviral bioactivities against tobacco mosaic virus (TMV) and cucumber mosaic virus (CMV) at 500 μg/mL. The relationship between structure and antiviral activity was also discussed. Compounds 5a, 6e, and 6g could possess appreciable protective bioactivities on TMV ex vivo by approximately 50% (EC50) at 257.7, 320.7 and 243.3 μg/mL. This study is the first to demonstrate that (1E, 4E)-1-aryl-5-(2-(quinazolin-4-yloxy)phenyl)-1,4-pentadien-3-one can be used to develop potential Virucides for plants.
Zhen Chen - One of the best experts on this subject based on the ideXlab platform.
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Synthesis and Antiviral Bioactivity of Novel (1E, 4E)‐1‐Aryl‐5‐(2‐(quinazolin‐4‐yloxy)phenyl)‐1,4‐pentadien‐3‐one Derivatives.
ChemInform, 2013Co-Authors: Hui Luo, Jiaju Liu, Linhong Jin, Zhen Chen, Song Yang, Baoan SongAbstract:For the first time it is demonstrates that the title compounds can be used to develop potential Virucides for plants.
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Synthesis and antiviral bioactivity of novel (1E, 4E)-1-aryl-5-(2-(quinazolin-4-yloxy)phenyl)-1,4-pentadien-3-one derivatives
European Journal of Medicinal Chemistry, 2013Co-Authors: Hui Luo, Jiaju Liu, Linhong Jin, Zhen Chen, Song Yang, Baoan SongAbstract:Abstract A series of novel (1E, 4E)-1-aryl-5-[2-(quinazolin-4-yloxy)phenyl]-1,4-pentadien-3-one derivatives were designed and synthesized by reacting substituent aldehyde with intermediates 4a–f. Antiviral bioassays indicated that most of the compounds exhibited promising ex vivo antiviral bioactivities against tobacco mosaic virus (TMV) and cucumber mosaic virus (CMV) at 500 μg/mL. The relationship between structure and antiviral activity was also discussed. Compounds 5a, 6e, and 6g could possess appreciable protective bioactivities on TMV ex vivo by approximately 50% (EC50) at 257.7, 320.7 and 243.3 μg/mL. This study is the first to demonstrate that (1E, 4E)-1-aryl-5-(2-(quinazolin-4-yloxy)phenyl)-1,4-pentadien-3-one can be used to develop potential Virucides for plants.
