Visceral Afferent Nerve

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Massimo Porena - One of the best experts on this subject based on the ideXlab platform.

  • botulinum a toxin injections into the detrusor muscle decrease Nerve growth factor bladder tissue levels in patients with neurogenic detrusor overactivity
    The Journal of Urology, 2006
    Co-Authors: Antonella Giannantoni, Savino M Di Stasi, Vincenza Nardicchi, Lara Macchioni, Vittorio Bini, Alessandro Zucchi, Gianfrancesco Goracci, Massimo Porena
    Abstract:

    Purpose: We investigated the effects of BTX-A on Visceral Afferent Nerve transmission by measuring bladder tissue NGF levels in patients with neurogenic detrusor overactivity before and after intravesical treatment with BTX-A. We also compared the bladder tissue NGF content with clinical and urodynamic data.Materials and Methods: A total of 23 patients underwent clinical evaluation and urodynamics with detection of the UDC threshold, maximum pressure and maximum cystometric capacity before, and at the 1 and 3-month followups. Endoscopic bladder wall biopsies were also obtained at the same time points. NGF levels were measured in tissue homogenate by enzyme-linked immunosorbent assay (Promega, Madison, Wisconsin).Results: At 1 and 3 months mean catheterization and incontinent episodes were significantly decreased (p <0.05 and <0.001, respectively). On urodynamics we detected a significant increase in the UDC threshold and maximum cystometric capacity, and a significant decrease in UDC maximum pressure at t...

  • Botulinum-A toxin injections into the detrusor muscle decrease Nerve growth factor bladder tissue levels in patients with neurogenic detrusor overactivity.
    The Journal of Urology, 2006
    Co-Authors: Antonella Giannantoni, Savino M Di Stasi, Vincenza Nardicchi, Lara Macchioni, Vittorio Bini, Alessandro Zucchi, Gianfrancesco Goracci, Massimo Porena
    Abstract:

    Purpose: We investigated the effects of BTX-A on Visceral Afferent Nerve transmission by measuring bladder tissue NGF levels in patients with neurogenic detrusor overactivity before and after intravesical treatment with BTX-A. We also compared the bladder tissue NGF content with clinical and urodynamic data.Materials and Methods: A total of 23 patients underwent clinical evaluation and urodynamics with detection of the UDC threshold, maximum pressure and maximum cystometric capacity before, and at the 1 and 3-month followups. Endoscopic bladder wall biopsies were also obtained at the same time points. NGF levels were measured in tissue homogenate by enzyme-linked immunosorbent assay (Promega, Madison, Wisconsin).Results: At 1 and 3 months mean catheterization and incontinent episodes were significantly decreased (p

Antonella Giannantoni - One of the best experts on this subject based on the ideXlab platform.

  • botulinum a toxin injections into the detrusor muscle decrease Nerve growth factor bladder tissue levels in patients with neurogenic detrusor overactivity
    The Journal of Urology, 2006
    Co-Authors: Antonella Giannantoni, Savino M Di Stasi, Vincenza Nardicchi, Lara Macchioni, Vittorio Bini, Alessandro Zucchi, Gianfrancesco Goracci, Massimo Porena
    Abstract:

    Purpose: We investigated the effects of BTX-A on Visceral Afferent Nerve transmission by measuring bladder tissue NGF levels in patients with neurogenic detrusor overactivity before and after intravesical treatment with BTX-A. We also compared the bladder tissue NGF content with clinical and urodynamic data.Materials and Methods: A total of 23 patients underwent clinical evaluation and urodynamics with detection of the UDC threshold, maximum pressure and maximum cystometric capacity before, and at the 1 and 3-month followups. Endoscopic bladder wall biopsies were also obtained at the same time points. NGF levels were measured in tissue homogenate by enzyme-linked immunosorbent assay (Promega, Madison, Wisconsin).Results: At 1 and 3 months mean catheterization and incontinent episodes were significantly decreased (p <0.05 and <0.001, respectively). On urodynamics we detected a significant increase in the UDC threshold and maximum cystometric capacity, and a significant decrease in UDC maximum pressure at t...

  • Botulinum-A toxin injections into the detrusor muscle decrease Nerve growth factor bladder tissue levels in patients with neurogenic detrusor overactivity.
    The Journal of Urology, 2006
    Co-Authors: Antonella Giannantoni, Savino M Di Stasi, Vincenza Nardicchi, Lara Macchioni, Vittorio Bini, Alessandro Zucchi, Gianfrancesco Goracci, Massimo Porena
    Abstract:

    Purpose: We investigated the effects of BTX-A on Visceral Afferent Nerve transmission by measuring bladder tissue NGF levels in patients with neurogenic detrusor overactivity before and after intravesical treatment with BTX-A. We also compared the bladder tissue NGF content with clinical and urodynamic data.Materials and Methods: A total of 23 patients underwent clinical evaluation and urodynamics with detection of the UDC threshold, maximum pressure and maximum cystometric capacity before, and at the 1 and 3-month followups. Endoscopic bladder wall biopsies were also obtained at the same time points. NGF levels were measured in tissue homogenate by enzyme-linked immunosorbent assay (Promega, Madison, Wisconsin).Results: At 1 and 3 months mean catheterization and incontinent episodes were significantly decreased (p

Savino M Di Stasi - One of the best experts on this subject based on the ideXlab platform.

  • botulinum a toxin injections into the detrusor muscle decrease Nerve growth factor bladder tissue levels in patients with neurogenic detrusor overactivity
    The Journal of Urology, 2006
    Co-Authors: Antonella Giannantoni, Savino M Di Stasi, Vincenza Nardicchi, Lara Macchioni, Vittorio Bini, Alessandro Zucchi, Gianfrancesco Goracci, Massimo Porena
    Abstract:

    Purpose: We investigated the effects of BTX-A on Visceral Afferent Nerve transmission by measuring bladder tissue NGF levels in patients with neurogenic detrusor overactivity before and after intravesical treatment with BTX-A. We also compared the bladder tissue NGF content with clinical and urodynamic data.Materials and Methods: A total of 23 patients underwent clinical evaluation and urodynamics with detection of the UDC threshold, maximum pressure and maximum cystometric capacity before, and at the 1 and 3-month followups. Endoscopic bladder wall biopsies were also obtained at the same time points. NGF levels were measured in tissue homogenate by enzyme-linked immunosorbent assay (Promega, Madison, Wisconsin).Results: At 1 and 3 months mean catheterization and incontinent episodes were significantly decreased (p <0.05 and <0.001, respectively). On urodynamics we detected a significant increase in the UDC threshold and maximum cystometric capacity, and a significant decrease in UDC maximum pressure at t...

  • Botulinum-A toxin injections into the detrusor muscle decrease Nerve growth factor bladder tissue levels in patients with neurogenic detrusor overactivity.
    The Journal of Urology, 2006
    Co-Authors: Antonella Giannantoni, Savino M Di Stasi, Vincenza Nardicchi, Lara Macchioni, Vittorio Bini, Alessandro Zucchi, Gianfrancesco Goracci, Massimo Porena
    Abstract:

    Purpose: We investigated the effects of BTX-A on Visceral Afferent Nerve transmission by measuring bladder tissue NGF levels in patients with neurogenic detrusor overactivity before and after intravesical treatment with BTX-A. We also compared the bladder tissue NGF content with clinical and urodynamic data.Materials and Methods: A total of 23 patients underwent clinical evaluation and urodynamics with detection of the UDC threshold, maximum pressure and maximum cystometric capacity before, and at the 1 and 3-month followups. Endoscopic bladder wall biopsies were also obtained at the same time points. NGF levels were measured in tissue homogenate by enzyme-linked immunosorbent assay (Promega, Madison, Wisconsin).Results: At 1 and 3 months mean catheterization and incontinent episodes were significantly decreased (p

Vincenza Nardicchi - One of the best experts on this subject based on the ideXlab platform.

  • botulinum a toxin injections into the detrusor muscle decrease Nerve growth factor bladder tissue levels in patients with neurogenic detrusor overactivity
    The Journal of Urology, 2006
    Co-Authors: Antonella Giannantoni, Savino M Di Stasi, Vincenza Nardicchi, Lara Macchioni, Vittorio Bini, Alessandro Zucchi, Gianfrancesco Goracci, Massimo Porena
    Abstract:

    Purpose: We investigated the effects of BTX-A on Visceral Afferent Nerve transmission by measuring bladder tissue NGF levels in patients with neurogenic detrusor overactivity before and after intravesical treatment with BTX-A. We also compared the bladder tissue NGF content with clinical and urodynamic data.Materials and Methods: A total of 23 patients underwent clinical evaluation and urodynamics with detection of the UDC threshold, maximum pressure and maximum cystometric capacity before, and at the 1 and 3-month followups. Endoscopic bladder wall biopsies were also obtained at the same time points. NGF levels were measured in tissue homogenate by enzyme-linked immunosorbent assay (Promega, Madison, Wisconsin).Results: At 1 and 3 months mean catheterization and incontinent episodes were significantly decreased (p <0.05 and <0.001, respectively). On urodynamics we detected a significant increase in the UDC threshold and maximum cystometric capacity, and a significant decrease in UDC maximum pressure at t...

  • Botulinum-A toxin injections into the detrusor muscle decrease Nerve growth factor bladder tissue levels in patients with neurogenic detrusor overactivity.
    The Journal of Urology, 2006
    Co-Authors: Antonella Giannantoni, Savino M Di Stasi, Vincenza Nardicchi, Lara Macchioni, Vittorio Bini, Alessandro Zucchi, Gianfrancesco Goracci, Massimo Porena
    Abstract:

    Purpose: We investigated the effects of BTX-A on Visceral Afferent Nerve transmission by measuring bladder tissue NGF levels in patients with neurogenic detrusor overactivity before and after intravesical treatment with BTX-A. We also compared the bladder tissue NGF content with clinical and urodynamic data.Materials and Methods: A total of 23 patients underwent clinical evaluation and urodynamics with detection of the UDC threshold, maximum pressure and maximum cystometric capacity before, and at the 1 and 3-month followups. Endoscopic bladder wall biopsies were also obtained at the same time points. NGF levels were measured in tissue homogenate by enzyme-linked immunosorbent assay (Promega, Madison, Wisconsin).Results: At 1 and 3 months mean catheterization and incontinent episodes were significantly decreased (p

Lara Macchioni - One of the best experts on this subject based on the ideXlab platform.

  • botulinum a toxin injections into the detrusor muscle decrease Nerve growth factor bladder tissue levels in patients with neurogenic detrusor overactivity
    The Journal of Urology, 2006
    Co-Authors: Antonella Giannantoni, Savino M Di Stasi, Vincenza Nardicchi, Lara Macchioni, Vittorio Bini, Alessandro Zucchi, Gianfrancesco Goracci, Massimo Porena
    Abstract:

    Purpose: We investigated the effects of BTX-A on Visceral Afferent Nerve transmission by measuring bladder tissue NGF levels in patients with neurogenic detrusor overactivity before and after intravesical treatment with BTX-A. We also compared the bladder tissue NGF content with clinical and urodynamic data.Materials and Methods: A total of 23 patients underwent clinical evaluation and urodynamics with detection of the UDC threshold, maximum pressure and maximum cystometric capacity before, and at the 1 and 3-month followups. Endoscopic bladder wall biopsies were also obtained at the same time points. NGF levels were measured in tissue homogenate by enzyme-linked immunosorbent assay (Promega, Madison, Wisconsin).Results: At 1 and 3 months mean catheterization and incontinent episodes were significantly decreased (p <0.05 and <0.001, respectively). On urodynamics we detected a significant increase in the UDC threshold and maximum cystometric capacity, and a significant decrease in UDC maximum pressure at t...

  • Botulinum-A toxin injections into the detrusor muscle decrease Nerve growth factor bladder tissue levels in patients with neurogenic detrusor overactivity.
    The Journal of Urology, 2006
    Co-Authors: Antonella Giannantoni, Savino M Di Stasi, Vincenza Nardicchi, Lara Macchioni, Vittorio Bini, Alessandro Zucchi, Gianfrancesco Goracci, Massimo Porena
    Abstract:

    Purpose: We investigated the effects of BTX-A on Visceral Afferent Nerve transmission by measuring bladder tissue NGF levels in patients with neurogenic detrusor overactivity before and after intravesical treatment with BTX-A. We also compared the bladder tissue NGF content with clinical and urodynamic data.Materials and Methods: A total of 23 patients underwent clinical evaluation and urodynamics with detection of the UDC threshold, maximum pressure and maximum cystometric capacity before, and at the 1 and 3-month followups. Endoscopic bladder wall biopsies were also obtained at the same time points. NGF levels were measured in tissue homogenate by enzyme-linked immunosorbent assay (Promega, Madison, Wisconsin).Results: At 1 and 3 months mean catheterization and incontinent episodes were significantly decreased (p